scholarly journals Decoding the neural dynamics of free choice in humans

2019 ◽  
Author(s):  
Thomas Thiery ◽  
Anne-Lise Saive ◽  
Etienne Combrisson ◽  
Arthur Dehgan ◽  
Julien Bastin ◽  
...  
Keyword(s):  
Decision Making ◽  
Working Memory ◽  
Free Choice ◽  
Temporal Dynamics ◽  
Motor Planning ◽  
Decision Task ◽  
Neural Activation ◽  
List Type ◽  
High Gamma ◽  
Eeg Recordings

SummaryHow do we choose a particular action among equally valid alternatives? Non-human primate findings have shown that decision-making implicates modulations in unit firing rates and local field potentials (LFPs) across frontal and parietal cortices. Yet the electrophysiological brain mechanisms that underlie free choice in humans remain ill defined. Here, we address this question using rare intracerebral EEG recordings in surgical epilepsy patients performing a delayed oculomotor decision task. We find that the temporal dynamics of high gamma (HG, 60-140 Hz) neural activity in distinct frontal and parietal brain areas robustly discriminate free choice from instructed saccade planning at the level of single trials. Classification analysis was applied to the LFP signals to isolate decision-related activity from sensory and motor planning processes. Compared to instructed saccades, free choice trials exhibited delayed and longer-lasting HG activity. The temporal dynamics of these sustained decision-related responses distinguished deliberation-related from working memory processes. Taken together, these findings provide the first direct electrophysiological evidence in humans for the role of sustained high-frequency neural activation in fronto-parietal cortex in mediating the intrinsically driven process of freely choosing among competing behavioral alternatives.HighlightsFirst intracerebral recordings in humans performing an oculomotor decision-making taskMachine learning analytics unravel underlying spectral and temporal brain dynamicsFree choice trials exhibit sustained fronto-parietal high gamma (HG) activity during the delayMaking a decision and maintaining it in working memory are associated with distinct sustained HG dynamics

scholarly journals Decoding the neural dynamics of free choice in humans

PLoS Biology ◽  
2020 ◽  
Vol 18 (12) ◽  
pp. e3000864
Author(s):  
Thomas Thiery ◽  
Anne-Lise Saive ◽  
Etienne Combrisson ◽  
Arthur Dehgan ◽  
Julien Bastin ◽  
...  
Keyword(s):  
Free Choice ◽  
Temporal Dynamics ◽  
Motor Planning ◽  
Decision Task ◽  
Neural Activation ◽  
Deliberation Process ◽  
High Gamma ◽  
Planning Processes ◽  
Eeg Recordings ◽  
Parietal Cortices

How do we choose a particular action among equally valid alternatives? Nonhuman primate findings have shown that decision-making implicates modulations in unit firing rates and local field potentials (LFPs) across frontal and parietal cortices. Yet the electrophysiological brain mechanisms that underlie free choice in humans remain ill defined. Here, we address this question using rare intracerebral electroencephalography (EEG) recordings in surgical epilepsy patients performing a delayed oculomotor decision task. We find that the temporal dynamics of high-gamma (HG, 60–140 Hz) neural activity in distinct frontal and parietal brain areas robustly discriminate free choice from instructed saccade planning at the level of single trials. Classification analysis was applied to the LFP signals to isolate decision-related activity from sensory and motor planning processes. Compared with instructed saccades, free-choice trials exhibited delayed and longer-lasting HG activity during the delay period. The temporal dynamics of the decision-specific sustained HG activity indexed the unfolding of a deliberation process, rather than memory maintenance. Taken together, these findings provide the first direct electrophysiological evidence in humans for the role of sustained high-frequency neural activation in frontoparietal cortex in mediating the intrinsically driven process of freely choosing among competing behavioral alternatives.

scholarly journals Noninvasively Decoding the Contents of Visual Working Memory in the Human Prefrontal Cortex within High-gamma Oscillatory Patterns

2012 ◽  
Vol 24 (2) ◽  
pp. 304-314 ◽  
Author(s):  
Rafael Polanía ◽  
Walter Paulus ◽  
Michael A. Nitsche
Keyword(s):  
Working Memory ◽  
Visual Working Memory ◽  
Animal Studies ◽  
Gamma Oscillations ◽  
Specific Information ◽  
Top Down ◽  
Population Activity ◽  
High Gamma ◽  
Long Time ◽  
Eeg Recordings

The temporal maintenance and subsequent retrieval of information that no longer exists in the environment is called working memory. It is believed that this type of memory is controlled by the persistent activity of neuronal populations, including the prefrontal, temporal, and parietal cortex. For a long time, it has been controversially discussed whether, in working memory, the PFC stores past sensory events or, instead, its activation is an extramnemonic source of top–down control over posterior regions. Recent animal studies suggest that specific information about the contents of working memory can be decoded from population activity in prefrontal areas. However, it has not been shown whether the contents of working memory during the delay periods can be decoded from EEG recordings in the human brain. We show that by analyzing the nonlinear dynamics of EEG oscillatory patterns it is possible to noninvasively decode with high accuracy, during encoding and maintenance periods, the contents of visual working memory information within high-gamma oscillations in the human PFC. These results are thus in favor of an active storage function of the human PFC in working memory; this, without ruling out the role of PFC in top–down processes. The ability to noninvasively decode the contents of working memory is promising in applications such as brain computer interfaces, together with computation of value function during planning and decision making processes.

scholarly journals Mindfulness meditators show enhanced working memory performance concurrent with different brain region engagement patterns during recall

2019 ◽  
Author(s):  
NW Bailey ◽  
G Freedman ◽  
K Raj ◽  
KN Spierings ◽  
LR Piccoli ◽  
...  
Keyword(s):  
Working Memory ◽  
Neural Activity ◽  
Memory Performance ◽  
Event Related Potentials ◽  
Response Strength ◽  
Neural Response ◽  
Neural Activation ◽  
List Type ◽  
Alpha Oscillations ◽  
Related Potentials

AbstractMindfulness meditation has been shown to improve working memory (WM). However, the altered brain activity underpinning these improvements is underexplored. In non-meditating individuals, modulation of theta and alpha oscillations and 1/f aperiodic activity during WM has been found to be related to WM performance. Resting theta and alpha oscillations have been found to differ in meditators, but WM related oscillation changes and 1/f aperiodic activity have not yet been examined. Additionally, WM event-related-potentials (ERPs) are modulated by attention, which is also enhanced by meditation, so these neural measures are candidates for exploring neural activity underpinning WM improvement in meditators. We recorded EEG from 29 controls and 29 meditators during a modified Sternberg WM task and compared theta, alpha, and 1/f aperiodic activity during the WM delay, and ERPs time-locked to the WM probe. Meditators responded more accurately (p = 0.008, Cohen’s d = 0.688). Meditators also showed different ERP distributions with earlier left-temporal activation and more frontal distribution of activity (FDR-p = 0.0186, η2 = 0.0903), as well as a reduction in overall neural response strength (FDR-p = 0.0098, η2 = 0.1251). While a higher proportion of meditators showed theta oscillations during the WM delay, no other differences in theta, alpha or 1/f aperiodic activity were present. These results suggest that increased WM performance in meditators might not be the result of higher amplitudes of typical WM activity, but instead due to an alternative neural strategy during WM decision making, which may allow more accurate responses with less neural activation.Highlights-Long term mindfulness meditators showed improved working memory (WM) accuracy-This was concurrent with earlier left temporal activation following probe stimuli-As well as a more frontal distribution and reduced overall neural response strength-No oscillation differences were present in the working memory delay period-Improved WM from altered neural strategy rather than increased neural activity

scholarly journals Prefrontal spatial working memory network predicts animal's decision making in a free choice saccade task

2016 ◽  
Vol 115 (1) ◽  
pp. 127-142 ◽  
Author(s):  
Kei Mochizuki ◽  
Shintaro Funahashi
Keyword(s):  
Decision Making ◽  
Working Memory ◽  
Network Architecture ◽  
Free Choice ◽  
Spatial Information ◽  
Spatial Working Memory ◽  
Visual Response ◽  
Memory Network ◽  
Saccade Direction ◽  
Saccade Task

While neurons in the lateral prefrontal cortex (PFC) encode spatial information during the performance of working memory tasks, they are also known to participate in subjective behavior such as spatial attention and action selection. In the present study, we analyzed the activity of primate PFC neurons during the performance of a free choice memory-guided saccade task in which the monkeys needed to choose a saccade direction by themselves. In trials when the receptive field location was subsequently chosen by the animal, PFC neurons with spatially selective visual response started to show greater activation before cue onset. This result suggests that the fluctuation of firing before cue presentation prematurely biased the representation of a certain spatial location and eventually encouraged the subsequent choice of that location. In addition, modulation of the activity by the animal's choice was observed only in neurons with high sustainability of activation and was also dependent on the spatial configuration of the visual cues. These findings were consistent with known characteristics of PFC neurons in information maintenance in spatial working memory function. These results suggest that precue fluctuation of spatial representation was shared and enhanced through the working memory network in the PFC and could finally influence the animal's free choice of saccade direction. The present study revealed that the PFC plays an important role in decision making in a free choice condition and that the dynamics of decision making are constrained by the network architecture embedded in this cortical area.

scholarly journals Age-related deficits in rapid visuomotor decision-making

2021 ◽  
Author(s):  
Ana Gómez-Granados ◽  
Deborah A. Barany ◽  
Margaret Schrayer ◽  
Isaac Kurtzer ◽  
Cédrick Bonnet ◽  
...  
Keyword(s):  
Older Adults ◽  
Decision Making ◽  
Task Demands ◽  
Decision Task ◽  
List Type ◽  
Perceptual Decision Making ◽  
Perceptual Decision ◽  
Initial Decision ◽  
Age Related ◽  
Decision Errors

AbstractMany goal-directed actions that require rapid visuomotor planning and perceptual decision-making are affected in older adults, causing difficulties in execution of many functional activities of daily living. Visuomotor planning and perceptual decision-making are mediated by the dorsal and ventral visual streams, respectively, but it is unclear how age-induced changes in sensory processing in these streams contribute to declines in goal-directed actions. Previously, we have shown that in healthy adults task demands affect the integration of sensory information between the two streams and more motorically demanding tasks induce earlier decisions and more decision errors. Here, we asked the question if older adults would exhibit larger declines in interactions between the two streams during demanding motor tasks. Older adults (n=15) and young controls (n=26) performed a simple reaching task and a more demanding interception task towards virtual objects. In some blocks of trials, participants also had to select an appropriate movement based on the shape of the object. Our results showed that older adults made a similar number of initial decision errors during both the reaching and interception tasks but corrected fewer of those errors during movement. During the more demanding interception decision task, older adults made more decision- and execution-related errors than young adults, which were related to early initiation of their movements. Together, these results suggest that older adults have a reduced ability to integrate new perceptual information to guide online action, which may reflect impaired ventral-dorsal stream interactions.HighlightsOlder adults showed reduced performance in a visuomotor decision-making taskInitial decision errors were similar between young and older adultsOlder adults were less likely to correct initial decision errorsMore demanding movements were associated with earlier and less accurate decisions

A Bird in the Hand Isn’t Good for Long

2018 ◽  
Vol 65 (1) ◽  
pp. 23-31 ◽  
Author(s):  
Stefan Scherbaum ◽  
Simon Frisch ◽  
Maja Dshemuchadse
Keyword(s):  
Decision Making ◽  
Cognitive Control ◽  
The Other ◽  
Decision Task ◽  
Short Term ◽  
Additional Time ◽  
Control Processes ◽  
Folk Wisdom ◽  
Study Participants ◽  
Insight Into

Abstract. Folk wisdom tells us that additional time to make a decision helps us to refrain from the first impulse to take the bird in the hand. However, the question why the time to decide plays an important role is still unanswered. Here we distinguish two explanations, one based on a bias in value accumulation that has to be overcome with time, the other based on cognitive control processes that need time to set in. In an intertemporal decision task, we use mouse tracking to study participants’ responses to options’ values and delays which were presented sequentially. We find that the information about options’ delays does indeed lead to an immediate bias that is controlled afterwards, matching the prediction of control processes needed to counter initial impulses. Hence, by using a dynamic measure, we provide insight into the processes underlying short-term oriented choices in intertemporal decision making.

7 Exploring healthcare professionals’ attitudes to future care planning with older adults in hospital: qualitative research co-design through multi-professional patient and carer involvement

2018 ◽  
Vol 8 (3) ◽  
pp. 362.2-362
Author(s):  
Anna-Maria Bielinska ◽  
Stephanie Archer ◽  
Catherine Urch ◽  
Ara Darzi
Keyword(s):  
Older Adults ◽  
Decision Making ◽  
End Of Life Care ◽  
Healthcare Professionals ◽  
List Type ◽  
Care Planning ◽  
Life Care ◽  
Topic Guide ◽  
Future Care ◽  
Advance Care

IntroductionDespite evidence that advance care planning in older hospital inpatients improves the quality of end-of-life care (Detering 2010) future care planning (FCP) with older adults remains to be normalised in hospital culture. It is therefore crucial to understand the attitudes of healthcare professionals to FCP in older patients in the hospital setting. Co-design with patients carers and healthcare professionals can generate more detailed meaningful data through better conversations.AimsTo co-design a semi-structured interview (SSI) topic guide to explore healthcare professionals’ attitudes to FCP with older adults in hospital.MethodsA multi-professional research group including a panel of patient and carer representatives co-designed an in-depth topic guide for a SSI exploring healthcare professionals’ attitudes to FCP with older adults in hospital.ResultsThe co-designed topic guide encourages participants to explore personal and system-level factors that may influence attitudes to FCP and practice in hospital amongst healthcare staff. Co-designed topics for inclusion in the SSI schedule include:Potential differences between specialist and generalist approaches to FCPThe influence of perceived hierarchy and emergency–decision making ability in professionals on FCP discussionsThe relevance to transitions of careAttitudes to FCP beyond the biomedical paradigm including perceived well–being and psychosocial aspects of careDigital FCP tools including patient–led FCP.ConclusionCo-designing qualitative research with older people and multi-disciplinary professionals may narrow translational gaps in implementing FCP by setting joint research priorities. Data generated from a co-designed study may expand understanding of hospital-based anticipatory decision-making with older adults.Reference. Detering KM, Hancock AD, Reade MC, Silvester W. The impact of advance care planning on end of life care in elderly patients: randomised controlled trial. BMJ23 March 2010;340:c1345.

The Legislative Decision-Making Process

1982 ◽  
Vol 32 ◽  
pp. 7-8
Author(s):  
Richard DeGraw ◽  
Bette F. DeGraw
Keyword(s):  
Decision Making ◽  
American Indians ◽  
Undergraduate Students ◽  
Community Organization ◽  
Role Play ◽  
The Political ◽  
Decision Making Process ◽  
List Type ◽  
Provision Of Services ◽  
Legislative Decision

The Legislative Decision Making Process is an educational role play for graduate or undergraduate students concerning the political and pressure relationships involved in the political decision-making process. The role play reviews the implications of the decision-making processes upon the provision of services by governmental agencies.The role play engages from twenty to sixty students in a simulated budget-making and lobbying experience and utilizes this experience to teach students:1.The values and pressures considered by bureaucracies and the Legislature in decision-making;2.The relationships which exist between clients, community groups, administrators and politicians;3.The various techniques of Community Organization for lobbying and Legislative influence.The role play consists of various groups of students in roles which include legislators, administrators of three major state departments, two minor state departments, parent groups, Concerned Citizen groups, American Indians disabled individuals and ex-clients.

Evaluating Risk-Propensity Assessment Methods: Patterns in Repeated Exposure to Emotional Stimuli

2020 ◽  
Vol 64 (1) ◽  
pp. 283-287
Author(s):  
Sahinya Susindar ◽  
Harrison Wissel-Littmann ◽  
Terry Ho ◽  
Thomas K. Ferris
Keyword(s):  
Decision Making ◽  
Emotion Regulation ◽  
Assessment Method ◽  
Decision Makers ◽  
Decision Task ◽  
Emotional States ◽  
Affective States ◽  
Risk Propensity ◽  
Emotional Stimuli ◽  
Comparison Results

In studying naturalistic human decision-making, it is important to understand how emotional states shape decision-making processes and outcomes. Emotion regulation techniques can improve the quality of decisions, but there are several challenges to evaluating these techniques in a controlled research context. Determining the effectiveness of emotion regulation techniques requires methodology that can: 1) reliably elicit desired emotions in decision-makers; 2) include decision tasks with response measures that are sensitive to emotional loading; and 3) support repeated exposures/trials with relatively-consistent emotional loading and response sensitivity. The current study investigates one common method, the Balloon Analog Risk Task (BART), for its consistency and reliability in measuring the risk-propensity of decision-makers, and specifically how the method’s effectiveness might change over the course of repeated exposures. With the PANASX subjective assessment serving for comparison, results suggest the BART assessment method, when applied over repeated exposures, is reduced in its sensitivity to emotional stimuli and exhibits decision task-related learning effects which influence the observed trends in response data in complex ways. This work is valuable for researchers in decision-making and to guide design for humans with consideration for their affective states.

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