Dietary patterns and knowledge perception of breast cancer risk patients

2017 ◽  
Vol 47 (2) ◽  
pp. 270-287 ◽  
Author(s):  
Suvasish Das Shuvo ◽  
Tanvir Ahmad ◽  
Dipak Kumar Paul ◽  
Md. Ashrafuzzaman Zahid
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Dietary Patterns ◽  
Principal Component ◽  
Marginal Effect ◽  
Poor Knowledge ◽  
Content Type ◽  
Increased Risk ◽  
Risk Patients

Purpose Breast cancer is the most increasing female cancer worldwide, including Bangladesh. The purpose of this study was to investigate the association between dietary patterns and knowledge perception of breast cancer risk patients in Bangladesh. Design/methodology/approach A questionnaire survey about 27 frequently consumed food items was conducted among 140 patients in Amader Gram Cancer Care & Research Center. A logistic regression was applied to estimate breast cancer risk. Dietary patterns were analyzed by the principal component analysis: the fat-rich foods (meat, oil, etc.), fruits, vegetables, sugar, tea, coffee, eggs and fish patterns. Findings The marginal effect of the logit model estimated an increased risk of breast cancer for a“Fatty Diet”, characterized by a higher consumption of milk (1.2 per cent, p < 0.01), vegetable oils and fats, butter (3.7 per cent, p < 0.05) and red meat (4.9 per cent, p < 0.05), but a decreased risk of breast cancer for a “Fruity and Vegetable Diet”, characterized by a higher consumption of fish (1.3 per cent, p < 0.01), chicken and eggs (5.1 per cent, p < 0.05), fruits (0.05 per cent, p < 0.01) and vegetables (2.9 per cent, p < 0.05). The findings of this study also suggested that weight (0.07 per cent, p < 0.01) and age (19 per cent, p < 0.05) were associated with an increased risk of breast cancer, but exercise (13 per cent, p < 0.05) reduced breast cancer risk. The findings also showed that maximum patients had inadequate knowledge on dietary and clinical factors of breast cancer risk, in addition to poor cancer screening practice. Poor knowledge and practice of breast screening were likely to lead to late stage presentation of breast cancer. Originality/value The authors found an association between the prudent dietary patterns and breast cancer risk and poor knowledge on nutrition and breast cancer.

scholarly journals Dietary Patterns and Breast Cancer Risk in Black Urban South African Women: The SABC Study

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4106
Author(s):  
Inarie Jacobs ◽  
Christine Taljaard-Krugell ◽  
Mariaan Wicks ◽  
Herbert Cubasch ◽  
Maureen Joffe ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
South African ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Conditional Logistic Regression ◽  
Principal Component ◽  
Processed Food ◽  
Food Groups

A total of 396 breast cancer cases and 396 population-based controls from the South African Breast Cancer study (SABC) matched on age and demographic settings was included. Validated questionnaires were used to collect dietary and epidemiological data. Dietary patterns were derived using principal component analysis with a covariance matrix from 33 food groups. Odds ratios and 95% confidence intervals were estimated using conditional logistic regression. A traditional, a cereal-dairy breakfast and a processed food dietary pattern were identified, which together explained 40.3% of the total variance in the diet. After adjusting for potential confounders, the traditional dietary pattern and cereal-dairy breakfast dietary pattern were inversely associated with breast cancer risk (highest tertile versus lowest tertile) (OR = 0.72, 95%CI: 0.57–0.89, p-trend = 0.004 and OR = 0.73, 95%CI: 0.59–0.90, p-trend = 0.004, respectively). The processed food dietary pattern was not significantly associated with breast cancer risk. The results of this study show that a traditional dietary pattern and a cereal-dairy breakfast dietary pattern may reduce the risk of developing breast cancer in this population.

scholarly journals Dietary pattern and breast cancer risk in Japanese women: the Japan Public Health Center-based Prospective Study (JPHC Study)

2016 ◽  
Vol 115 (10) ◽  
pp. 1769-1779 ◽  
Author(s):  
Sangah Shin ◽  
Eiko Saito ◽  
Manami Inoue ◽  
Norie Sawada ◽  
Junko Ishihara ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Menopausal Status ◽  
Japanese Women ◽  
Hazard Ratios ◽  
Increased Risk

AbstractEvidence that diet is associated with breast cancer risk is inconsistent. Most of the studies have focused on risks associated with specific foods and nutrients, rather than overall diet. In this study, we aimed to evaluate the association between dietary patterns and breast cancer risk in Japanese women. A total of 49 552 Japanese women were followed-up from 1995 to 1998 (5-year follow-up survey) until the end of 2012 for an average of 14·6 years. During 725 534 person-years of follow-up, 718 cases of breast cancer were identified. We identified three dietary patterns (prudent, westernised and traditional Japanese). The westernised dietary pattern was associated with a 32 % increase in breast cancer risk (hazard ratios (HR) 1·32; 95 % CI 1·03, 1·70; Ptrend=0·04). In particular, subjects with extreme intake of the westernised diet (quintile (Q) Q5_5th) had an 83 % increase in risk of breast cancer in contrast to those in the lowest Q1 (HR 1·83; 95 % CI 1·25, 2·68; Ptrend=0·01). In analyses stratified by menopausal status, postmenopausal subjects in the highest quintile of the westernised dietary pattern had a 29 % increased risk of breast cancer (HR 1·29; 95 % CI 0·99, 1·76; Ptrend=0·04). With regard to hormone receptor status, the westernised dietary pattern was associated with an increased risk of oestrogen receptor-positive/progesterone receptor-positivetumours (HR 2·49; 95 % CI 1·40, 4·43; Ptrend<0·01). The other dietary patterns were not associated with the risk of breast cancer in Japanese women. A westernised dietary pattern is associated with an increased risk of breast cancer in Japanese women.

scholarly journals Dietary Patterns and Breast Cancer Risk: A KCPS-II Cohort Study

2021 ◽  
Author(s):  
Ji-Young Lee ◽  
Hae in Cho ◽  
Sun ha Jee
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Dietary Factors ◽  
Korean Women ◽  
High Intake ◽  
The Third ◽  
Increased Risk

Abstract Background: There have been inconsistencies in the evidence for a role of dietary risk factors in the development of breast cancer. In this study, we used a large-scale cohort (Korean Cancer Prevention Study-II [KCPS-II]) to examine the association between dietary patterns and breast cancer risk in Korean women.Methods: The dietary patterns of 14,807 women from the KCPS-II were derived by factor analysis and 135 cases of breast cancer were diagnosed during the follow-up period. Cox proportional models were used to estimate the hazard ratios (HR) and 95% confidence intervals (CI) for the risk of breast cancer. Results: The following three major dietary factors were identified: “Korean dietary pattern” (high intake of Kimchi, vegetables, and rice); “Sweet dietary pattern” (high intake of soda and sugar); and “Western-like dietary pattern” (high intake of dairy products, eggs, oil, fruits, and bread). After adjusting for potential confounders, neither the Korean (HR for the highest compared with the lowest tertile, 1.04; 95% CI 0.53−2.06) nor the Sweet dietary patterns were associated with the risk of breast cancer. In contrast, the Western-like dietary pattern was found to be significantly associated with an increased risk of breast cancer with an HR (95% CI) of 1.01 (0.65−1.60) for the second tertile and 1.61 (1.04−2.50) for the third tertile as compared with the lowest tertile. After stratifying by menopausal status, these effects were only statistically significant among premenopausal women for the third tertile, compared with those in the bottom tertile (HR 1.69; 95% CI 1.06−2.68; p = 0.028). No significant association was observed between the Korean or Sweet dietary pattern and breast cancer among either pre- or postmenopausal women.Conclusions: Our findings revealed that a greater consumption of a Western-like diet was associated with an increased breast cancer risk and consequently offer a potential prevention strategy for Korean women.

СONTRIBUTION OF POLYMORPHIC VARIATION OF ТP53 AND XRCC1 GENES TO THE SUSCEPTIBILITY TO BREAST CANCER FOR WOMEN OF KYRGYZ AND BELARUSIAN NATIONALITY - A COMPARATIVE STUDY ON MULTIFACTOR DIMENSIONALITY REDUCTION METHODS

2018 ◽  
Vol 64 (1) ◽  
pp. 95-101
Author(s):  
Nazira Aldasheva ◽  
Vyacheslav Kipen ◽  
Zhaynagul Isakova ◽  
Sergey Melnov ◽  
Raisa Smolyakova ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Dimensionality Reduction ◽  
Multifactor Dimensionality Reduction ◽  
Rflp Analysis ◽  
Kyrgyz Republic ◽  
Increased Risk ◽  
Polymorphic Variants ◽  
The Republic

Basing on Multifactor Dimensionality Reduction method we showed that polymorphic variants p.Q399R (rs25487, XRCC1) and p.P72R (rs1042522, TP53) correlated with increased risk of breast cancer for women from the Kyrgyz Republic and the Republic of Belarus. Cohort for investigation included patients with clinically verified breast cancer: 117 women from the Kyrgyz Republic (nationality - Kyrgyz) and 169 - of the Republic of Belarus (nationality - Belarusians). Group for comparison included (healthy patients without history of cancer pathology at the time of blood sampling) 102 patients from the Kyrgyz Republic, 185 - from the Republic of Belarus. Respectively genotyping of polymorphic variants p.Q399R (rs25487, XRCC1) and p.P72R (rs1042522, TP53) was done by PCR-RFLP. Analysis of the intergenic interactions conducted with MDR 3.0.2 software. Both ethnic groups showed an increase of breast cancer risk in the presence of alleles for SNPs Gln p.Q399R (XRCC1) in the heterozygous state: for the group “Kyrgyz” - OR=2,78 (95% CI=[1,60-4,82]), p=0,001; for the group “Belarusians” - OR=1,85 (95% СІ=[1Д1-2,82], p=0,004. Carriers with combination of alleles Gln (p.Q399R, XRCC1) and Pro (p.P72R, TP53) showed statistically significance increases of breast cancer risk as for patients from the Kyrgyz Republic (OR=2,89, 95% CI=[1,33-6,31]), so as for patients from the Republic of Belarus (OR=3,01, 95% CI=[0,79-11,56]).

scholarly journals Transiently increased risk of breast cancer after childbirth: implications for fertility treatments and surrogacy

2020 ◽  
Vol 35 (6) ◽  
pp. 1253-1255
Author(s):  
Zeev Blumenfeld ◽  
Norbert Gleicher ◽  
Eli Y Adashi
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Meta Analysis ◽  
Small Degree ◽  
Short Term ◽  
Benefit Ratio ◽  
Professional Societies ◽  
Fertility Treatments ◽  
Increased Risk

Abstract Whereas longstanding dogma has purported that pregnancies protect women from breast cancer, a recent meta-analysis now mandates reconsideration since it reported an actual higher breast cancer risk for more than two decades after childbirth before the relative risk turns negative. Moreover, the risk of breast cancer appears higher for women having their first birth at an older age and with a family history and it is not reduced by breastfeeding. The process of obtaining informed consent for all fertility treatments, therefore, must make patients aware of the facts that every pregnancy, to a small degree, will increase the short-term breast cancer risk. This observation may be even more relevant in cases of surrogacy where women agree to conceive without deriving benefits of offspring from assuming the risk, thus creating a substantially different risk-benefit ratio. Consequently, it appears prudent for professional societies in the field to update recommendations regarding consent information for all fertility treatments but especially for treatments involving surrogacy.

Association of APC and MCC Polymorphisms with Increased Breast Cancer Risk in an Indian Population

2011 ◽  
Vol 26 (1) ◽  
pp. 43-49 ◽  
Author(s):  
Nupur Mukherjee ◽  
Nilanjana Bhattacharya ◽  
Satyabrata Sinha ◽  
Neyaz Alam ◽  
Runu Chakravarti ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Signaling Pathway ◽  
Wnt Signaling Pathway ◽  
Minor Allele ◽  
Nucleotide Polymorphisms ◽  
Breast Cancer Patients ◽  
Increased Risk ◽  
Risk Of Cancer

The adenomatous polyposis coli (APC) and mutated in colorectal cancer (MCC) genes are key regulatory genes of the Wnt/β-catenin signaling pathway, which are independently involved in maintaining low levels of β-catenin in the cell. In addition to genetic and epigenetic alterations, some genetic polymorphisms in the genes associated with the Wnt signaling pathway have been reported to be associated with an increased risk of cancer, including breast cancer. In the present study we analyzed the association of genotype and haplotype status of two single nucleotide polymorphisms (SNPs), rs2229992 and rs11283943, in the APC and MCC genes, respectively, with an increased risk of breast carcinogenesis in a breast cancer and control population from eastern India. We observed a significant association of the rs11283943 SNP with increased breast cancer risk. Two specific haplotypes involving the minor allele of rs11283943 were found to be associated with an increased breast cancer risk. Kaplan-Meier curves showed a significant association of the 2–2 genotype (genotype homozygous for the rs11283943 minor allele) with decreased survival (p=0.045) of the breast cancer patients in our study, in particular patients with early-onset BC.

Sign in / Sign up

Export Citation Format

Share Document