The rapid development of economic globalization and the promotion of emerging technologies have spawned a Service-oriented logic that gradually dominates the contemporary industry, and the path for manufacturing companies to improve performance has become more and more complicated. Based on this background, the article uses the data of A-share listed companies in the manufacturing industry in the Yangtze River Delta and the Pearl River Delta in 2019, and uses the research method of fuzzy set qualitative comparative analysis to empirically study the core path and mechanism of multiple complex factors that affect corporate performance. The research results show that manufacturing companies can choose four paths to improve corporate performance (supply chain integration-driven based on internal control, servicing and market dual logic based on internal control-based integration-driven, relying on exploration and innovation-based integration-driven, Relying on the integration-driven type of dual innovation and balance), and found that the core role of supply chain integration and servicing level has become more prominent, becoming a key factor leading to high corporate performance. This research is helpful to identify the influence mechanism of supply chain integration, service level and other factors on corporate performance, and grasp the core of configuration, which has certain reference significance for corporate managers.