Reinforcement of Neuropixels probes for high-density neural recording in non-human primates**This work is supported by National Key RD Program of China (Grant No. 2017YFA0701102), Shanghai Science and Technology Committee, China (Grant No. 18JC1415102), Shanghai Municipal Science and Technology Major Project (Grant No. 2018SHZDZX05), National Natural Science Foundation of China (Grant No. 31800869), and Strategic Priority Research Program of Chinese Academy of Science (Grant No. XDB32040100).

2021 ◽  
Author(s):  
Qifan Wang ◽  
Jiapeng Yin ◽  
He Cui
Keyword(s):  
Research Program ◽  
Natural Science ◽  
Science And Technology ◽  
Neural Recording ◽  
High Density ◽  
Major Project

scholarly journals GAMTAMOKSLINIO IR TECHNOLOGINIO UGDYMO TOBULINIMAS: KELETAS ŠTRICHŲ [SCIENCE AND TECHNOLOGY EDUCATION DEVELOPMENT: SOME FEATURES]

2015 ◽  
Vol 7 (2) ◽  
pp. 56-58
Author(s):  
Vincentas Lamanauskas
Keyword(s):  
Technology Education ◽  
Science Teachers ◽  
Education System ◽  
Natural Science ◽  
Teaching And Learning ◽  
Rapid Development ◽  
Science And Technology ◽  
Scientific Conference ◽  
School Practice ◽  
Science And Technology Education

The perspectives of the improvement of natural science and technology education remains actual at all levels of an education system. Rapid development of science and technologies creates new challenges for an education system. Undoubtedly, natural science and technology education is a major factor of economic development of society. Deep concern is created by that fact that in some countries the tendency of decrease in the interest of youth to science in general is observed. It is obvious that it is necessary to reconsider the existing strategies of natural science and technology education. In this regard it is important to develop qualitatively new strategies and techniques of teaching and learning. A key task, there is a development of professional competences of science teachers, systemic improvement of teacher education in universities. Two important events are briefly presented in this editorial. The first Baltic Symposium on science and technology education was organized in Lithuania in June 2015. During the symposium participants shared experience, presented the latest scientific researches, and also examined some perspectives of natural science and technology education in the Baltic States. The second event is scientific methodical conference “Natural Science Education in a Comprehensive School” which is focused on school practice. It was organized in the Veisiejai gymnasium in April 2015. The presented scientific events undoubtedly have an influence on a development of science and technology education in general. Key words: science and technology education, scientific conference, school practice.

Nanotechnology and Their Applications in Science and Technology - Review

2021 ◽  
Vol 8 (1) ◽  
Keyword(s):  
Natural Science ◽  
Physical Science ◽  
Materials Science ◽  
Science And Technology ◽  
Nanometer Scale ◽  
Food Handling ◽  
Novel Materials ◽  
Food Applications ◽  
Nano Science ◽  
Technology Review

Nanotechnology is the investigation of tiny designs, having size of 0.1 to 100 nm. Nano medication is a generally new field of science and innovation. Brief clarification of different sorts of drug nano frameworks is given. Nanotechnology is serving to significantly improve, even alter, numerous innovation and industry areas: data innovation, energy, natural science, medication, country security, sanitation, and transportation, among numerous others. The present nanotechnology tackles current advancement in science, physical science, materials science, and biotechnology to make novel materials that have interesting properties on the grounds that their designs are resolved on the nanometer scale. Ongoing advances in Nano science and nanotechnology plan new and inventive applications in the food business. Nanotechnology presented to be a productive strategy in numerous fields, especially the food business and the space of utilitarian food varieties. However just like the condition with the development of any original food handling innovation, food bundling material, or food fixing, extra investigations are expected to exhibit the possible advantages of nanotechnologies and designed nanomaterial intended for use in food varieties without antagonistic wellbeing impacts. Nano emulsions show various benefits over customary emulsions because of the little beads size they contain: high optical lucidity, phenomenal actual consistency against gravitational parcel and drop aggregation, and further developed bio-availability of typified materials, which make them appropriate for food applications.

Natural Law and Mechanical Engineering

1984 ◽  
Vol 3 (1) ◽  
pp. 29-33
Author(s):  
P. C. Haarhoff
Keyword(s):  
Social Sciences ◽  
Natural Law ◽  
Natural Science ◽  
Mechanical Engineering ◽  
Science And Technology ◽  
Social Progress ◽  
Human Sciences ◽  
Technological Revolution ◽  
Social Standards ◽  
The Social

The first technological revolution, in the fourth millennium BC, was followed by immense social progress. The second revolution, which is now taking place, could lead to an even greater development in the human sciences, by setting men free from their daily struggle for existence while simultaneously exacting high social standards. Natural law - the “marriage between the ways of heaven and the ways of earth” of the Chinese - represents a route to such progress. In natural science and technology, natural law demands that conclusions be based on observation rather than speculation. The social sciences would do well to follow this example.

The Role Of Epithelial To Mesenchymal Transition In The Remodeling Of Lung Injury Induced By Acute Graft-Versus-Host Disease

Blood ◽  
2013 ◽  
Vol 122 (21) ◽  
pp. 3257-3257
Author(s):  
Meiqing Wu ◽  
Can Liu ◽  
Ke Zhao ◽  
Xiuli Wu ◽  
Yu Zhang ◽  
...  
Keyword(s):  
Public Health ◽  
Lung Injury ◽  
Natural Science ◽  
Research Funding ◽  
Science And Technology ◽  
Alveolar Epithelial Cells ◽  
Control Group ◽  
Technology Program ◽  
Alveolar Epithelial ◽  
National Public Health

Abstract Background Noninfectious lung injury caused by graft-versus-graft disease (GVHD) is a life-threatening complication after allogeneic hematopoietic stem cell transplant (allo-HSCT). Epithelial injury is a central event in the pathogenesis of noninfectious lung injury. Recent studies have shown that alveolar epithelial cells are able to self-renew and reestablish a functional alveolar epithelium. In the inflammatory and fibrotic lung diseases, differentiated epithelia also can acquire a myofibroblast phenotype in the process termed epithelial to mesenchymal transition (EMT), which contributes to aberrant healing and fibrosis. Many factors such as inflammatory cytokine TGF-β have been suggested to induce EMT. However, the role of EMT in the remodeling of acute GVHD (aGVHD) induced lung injury is unclear. Methods BALB/c mice were lethally irradiated and transplanted T cell-deleted (TCD) bone marrow plus whole spleen cells from C57BL/6 mice as aGVHD group, and only transplanted TCD bone marrow cells as control group. Alveolar epithelial cells were isolated from mice of two groups and Ep-CAM expression was measured by flow cytometry. The mRNA expression of cytokines including IFN-γ, TNF-α and TGF-β was detected by RT-PCR. The mRNA and protein expressions of specific markers, including E-cadherin, vimentin, Snail and surfactant proteins (SP)-C in lung tissue, were detected by RT-PCR and western blot. Results All mice in the aGVHD group showed diffuse periluminal infiltrates and parenchymal pneumonitis by histopathology, while the mice in the control group did not show any lung injury evidence. IFN-γ, TNF-α, TGF-β mRNA expressions were markedly up-regulated in the lung injury group as compared to the control group (P=0.045, P=0.032, P=0.025). Alveolar epithelial cells of injured lung expressed higher Ep-CAM (P=0.017) and lower SP-C (P=0.023). RT-PCR and western blot analyses revealed a significant decrease in epithelial marker E-cadherin (P=0.029) and increase in mesenchymal marker vimentin (P=0.026) in the GVHD damaged lung. Snail, a key EMT related transcription factor, was significantly elevated at mRNA and protein level in comparison to control group (P=0.015). Conclusion EMT is involving in the remodeling of lung injury induced by aGVHD. TGF-β is demonstrated to induce EMT. Whether up-regulation of IFN-γ and TNF-α contributes to EMT is deserved to be further explored. Disclosures: Wu: 863 Program (No. 2011AA020105) and National Public Health Grand Research Foundation ( No. 201202017): Research Funding; National Natural Science Foundation of China (Grant No.81000231, No.81270647) and Science and Technology Program of Guangzhou of China (11A72121174): Research Funding. Liu:863 Program (No. 2011AA020105) and National Public Health Grand Research Foundation ( No. 201202017): Research Funding; National Natural Science Foundation of China (Grant No.81000231, No.81270647) and Science and Technology Program of Guangzhou of China (11A72121174): Research Funding. Zhao:863 Program (No. 2011AA020105) and National Public Health Grand Research Foundation ( No. 201202017): Research Funding; National Natural Science Foundation of China (Grant No.81000231, No.81270647) and Science and Technology Program of Guangzhou of China (11A72121174): Research Funding. Wu:863 Program (No. 2011AA020105) and National Public Health Grand Research Foundation ( No. 201202017): Research Funding; National Natural Science Foundation of China (Grant No.81000231, No.81270647) and Science and Technology Program of Guangzhou of China (11A72121174): Research Funding. Zhang:863 Program (No. 2011AA020105) and National Public Health Grand Research Foundation ( No. 201202017): Research Funding; National Natural Science Foundation of China (Grant No.81000231, No.81270647) and Science and Technology Program of Guangzhou of China (11A72121174): Research Funding. Fan:863 Program (No. 2011AA020105) and National Public Health Grand Research Foundation ( No. 201202017): Research Funding; National Natural Science Foundation of China (Grant No.81000231, No.81270647) and Science and Technology Program of Guangzhou of China (11A72121174): Research Funding. Fan:863 Program (No. 2011AA020105) and National Public Health Grand Research Foundation ( No. 201202017): Research Funding; National Natural Science Foundation of China (Grant No.81000231, No.81270647) and Science and Technology Program of Guangzhou of China (11A72121174): Research Funding. Yin:863 Program (No. 2011AA020105) and National Public Health Grand Research Foundation ( No. 201202017): Research Funding; National Natural Science Foundation of China (Grant No.81000231, No.81270647) and Science and Technology Program of Guangzhou of China (11A72121174): Research Funding. Zheng:863 Program (No. 2011AA020105) and National Public Health Grand Research Foundation ( No. 201202017): Research Funding; National Natural Science Foundation of China (Grant No.81000231, No.81270647) and Science and Technology Program of Guangzhou of China (11A72121174): Research Funding. Yi:863 Program (No. 2011AA020105) and National Public Health Grand Research Foundation ( No. 201202017): Research Funding; National Natural Science Foundation of China (Grant No.81000231, No.81270647) and Science and Technology Program of Guangzhou of China (11A72121174): Research Funding. Liu:863 Program (No. 2011AA020105) and National Public Health Grand Research Foundation ( No. 201202017): Research Funding; National Natural Science Foundation of China (Grant No.81000231, No.81270647) and Science and Technology Program of Guangzhou of China (11A72121174): Research Funding.

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