Sidewall Imaging of Microarray-based Biosensor Using an Orthogonal Cantilever Probe

Author(s):  
Junyuan Geng ◽  
Hao Zhang ◽  
Xianghe Meng ◽  
Weibin Rong ◽  
Hui Xie
Keyword(s):  
Soft Matter ◽  
2021 ◽  
Author(s):  
Ruri Hidema ◽  
Ken-ya Fujito ◽  
Hiroshi Suzuki

The drag force of polyethyleneglycol thiol (mPEG-SH) attached to a cantilever probe in the flows of glycerol and polyethyleneglycol (PEG) solutions was measured. The effects of the molecular weights of...


2001 ◽  
Vol 40 (28) ◽  
pp. 5040 ◽  
Author(s):  
Gregor Schürmann ◽  
Wilfried Noell ◽  
Urs Staufer ◽  
Nico F. de Rooij ◽  
Rolf Eckert ◽  
...  

Author(s):  
Andrew J. Dick

The dynamic behavior of an atomic force microscope cantilever probe is studied for dual frequency excitation. By using the Euler-Bernoulli beam equation with a multi-mode approximation, the system is modeled with base excitation and tip-sample interaction forces obtain from molecular dynamics simulations. The dynamic response of the cantilever probe is simulated for a range of separation distance values and analyzed using Poincare´ sections, bifurcation diagrams, and spectral analysis. The response of the cantilever probe is found to display a qualitative change when influenced by surface forces. The frequency component at half of the fundamental frequency provides an effective way to monitor the amount of force that the probe is applying to the surface of the sample. With this frequency component, an amplitude modulation operation mode is proposed in order to maintain near-grazing behavior during imaging.


Author(s):  
Dale J. Meier

The invention of the scanning tunneling microscope (STM) by Binnig and Rohrer in 1982 demonstrated an unparalleled ability to image materials at the sub-nanometer scale. The invention rapidly lead to an explosion of applications of STM in a wide variety of fields. However, imaging by an STM is essentially limited to materials which are conductive, or could be made conductive, so many materials of interest could not be imaged by STM. This limitation was removed a few years later (1985) by the invention of the atomic force microscope (AFM) by Binnig, Quate and Gerber, in which imaging is based on the response of a soft cantilever beam to the contact forces between an ultra-fine probe tip and a sample. The cantilever/probe systems could be made sensitive enough to enable the AFM to easily resolve atomic or molecular level features.


2004 ◽  
Vol 35 (5) ◽  
pp. 479-483 ◽  
Author(s):  
Zunxian Yang ◽  
Xinxin Li ◽  
Yuelin Wang ◽  
Haifei Bao ◽  
Min Liu

Sign in / Sign up

Export Citation Format

Share Document