scholarly journals Dietary grape seed proanthocyanidins improved growth, immunity, antioxidant, digestive enzymes activities, and intestinal microbiota of juvenile hybrid sturgeon ( Acipenser baeri Brandt ♀ ×  A. schrenckii Brandt ♂)

2021 ◽  
Author(s):  
Guanling Xu ◽  
Wei Xing ◽  
Tieliang Li ◽  
Huanhuan Yu ◽  
Shibo Wei ◽  
...  
Keyword(s):  
Intestinal Microbiota ◽  
Digestive Enzymes ◽  
Grape Seed ◽  
Enzymes Activities ◽  
Grape Seed Proanthocyanidins ◽  
Acipenser Baeri ◽  
Hybrid Sturgeon

scholarly journals Enteritis in hybrid sturgeon (Acipenser schrenckii♂ × Acipenser baeri♀) caused by intestinal microbiota disorder

2020 ◽  
Vol 18 ◽  
pp. 100456
Author(s):  
Xiaoli Huang ◽  
Liang Zhong ◽  
Wei Fan ◽  
Yang Feng ◽  
Guanqing Xiong ◽  
...  
Keyword(s):  
Intestinal Microbiota ◽  
Acipenser Baeri ◽  
Hybrid Sturgeon

scholarly journals Dietary grape seed proanthocyanidins (GSPs) improve weaned intestinal microbiota and mucosal barrier using a piglet model

Oncotarget ◽  
2016 ◽  
Vol 7 (49) ◽  
pp. 80313-80326 ◽  
Author(s):  
Meng Han ◽  
Peixia Song ◽  
Chang Huang ◽  
Arash Rezaei ◽  
Shabnam Farrar ◽  
...  
Keyword(s):  
Intestinal Microbiota ◽  
Grape Seed ◽  
Mucosal Barrier ◽  
Grape Seed Proanthocyanidins

Effects of Bacillus subtilis on growth, digestive enzyme activity, and non-specific immunity in hybrid sturgeon (Acipenser baeri ♂×Acipenser schrenkii ♀) juveniles

2013 ◽  
Vol 18 (6) ◽  
pp. 1315-1320 ◽  
Author(s):  
Xiaoyong LIU ◽  
Ying ZHANG ◽  
Qian QI ◽  
Mingjun ZHAO ◽  
Likai MAI ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Bacillus Subtilis ◽  
Digestive Enzyme ◽  
Digestive Enzyme Activity ◽  
Acipenser Baeri ◽  
Specific Immunity ◽  
Hybrid Sturgeon

Grape Seed Proanthocyanidins Protect N2a Cells against Ischemic Injury via Endoplasmic Reticulum Stress and Mitochondrial-associated Pathways

2019 ◽  
Vol 18 (4) ◽  
pp. 334-341 ◽  
Author(s):  
Kun Fu ◽  
Liqiang Chen ◽  
Lifeng Miao ◽  
Yan Guo ◽  
Wei Zhang ◽  
...  
Keyword(s):  
Membrane Potential ◽  
Cell Viability ◽  
Mitochondrial Membrane Potential ◽  
Mitochondrial Membrane ◽  
Grape Seed ◽  
Mrna Levels ◽  
Dependent Manner ◽  
Grape Seed Proanthocyanidins ◽  
N2a Cells ◽  
Caspase 12

Background/Objective: Grape seed proanthocyanidins (GSPs) are a group of polyphenolic bioflavonoids, which possess a variety of biological functions and pharmacological properties. We studied the neuroprotective effects of GSP against oxygen-glucose deprivation/reoxygenation (OGD/R) injury and the potential mechanisms in mouse neuroblastoma N2a cells. Methods: OGD/R was conducted in N2a cells. Cell viability was evaluated by CCK-8 and LDH release assay. Apoptosis was assessed by TUNEL staining and flow cytometry. Protein levels of cleaved caspase-3, Bax and Bcl-2 were detected by Western blotting. CHOP, GRP78 and caspase-12 mRNA levels were assessed by real-time PCR. JC-1 dying was used to detect mitochondrial membrane potential. ROS levels, activities of endogenous antioxidant enzymes and ATP production were examined to evaluate mitochondrial function. Results: GSP increased cell viability after OGD/R injury in a dose-dependent manner. Furthermore, GSP inhibited cell apoptosis, reduced the mRNA levels of CHOP, GRP78 and caspase-12 (ER stressassociated genes), restored mitochondrial membrane potential and ATP generation, improved activities of endogenous anti-oxidant ability (T-AOC, GXH-Px, and SOD), and decreased ROS level. Conclusion: Our findings suggest that GSP can protect N2a cells from OGD/R insult. The mechanism of anti-apoptotic effects of GSP may involve attenuating ER stress and mitochondrial dysfunction.

scholarly journals Impact of starvation on digestive enzymes activities and plasma metabolites in Siberian sturgeon ( Acipenser baerii , Brandt, 1869)

2020 ◽  
Vol 51 (4) ◽  
pp. 1689-1699
Author(s):  
Sedigheh Babaei ◽  
Abdolmohammad Abedian-Kenari ◽  
Mahmood Naseri ◽  
Mohammad Ali Yazdani-Sadati ◽  
Isidoro Metón
Keyword(s):  
Digestive Enzymes ◽  
Siberian Sturgeon ◽  
Plasma Metabolites ◽  
Acipenser Baerii ◽  
Enzymes Activities

scholarly journals Grape seed proanthocyanidins reactivate silenced tumor suppressor genes in human skin cancer cells by targeting epigenetic regulators

2012 ◽  
Vol 263 (1) ◽  
pp. 122-130 ◽  
Author(s):  
Mudit Vaid ◽  
Ram Prasad ◽  
Tripti Singh ◽  
Virginia Jones ◽  
Santosh K. Katiyar
Keyword(s):  
Skin Cancer ◽  
Tumor Suppressor ◽  
Cancer Cells ◽  
Human Skin ◽  
Tumor Suppressor Genes ◽  
Grape Seed ◽  
Suppressor Genes ◽  
Grape Seed Proanthocyanidins ◽  
Epigenetic Regulators

Grape seed proanthocyanidins repress the hepatic lipid regulators miR-33 and miR-122 in rats

2012 ◽  
Vol 56 (11) ◽  
pp. 1636-1646 ◽  
Author(s):  
Laura Baselga-Escudero ◽  
Cinta Bladé ◽  
Aleix Ribas-Latre ◽  
Ester Casanova ◽  
M. Josepa Salvadó ◽  
...  
Keyword(s):  
Grape Seed ◽  
Hepatic Lipid ◽  
Grape Seed Proanthocyanidins ◽  
Lipid Regulators
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