Migraine Treatment in Pregnant Women Presenting to Acute Care: A Retrospective Observational Study

2018 ◽  
Vol 59 (2) ◽  
pp. 173-179 ◽  
Author(s):  
Katherine T. Hamilton ◽  
Matthew S. Robbins
BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e023654 ◽  
Author(s):  
Kana Yamamoto ◽  
Shuhei Nomura ◽  
Masaharu Tsubokura ◽  
Michio Murakami ◽  
Akihiko Ozaki ◽  
...  

ObjectivesThis study aimed to evaluate the internal cesium (Cs) level among pregnant women in Minamisoma City (the area straddling the evacuation zones) over a 5-year period after Japan’s 2011 Fukushima nuclear accident and assess the status and transition of their food-acquiring preferences during this period.DesignA retrospective observational study of a screening along with a questionnaire survey.SettingThis study was conducted in an obstetrics and gynaecology service in Minamisoma City in Fukushima, Japan.ParticipantsParticipants included pregnant women who applied for the voluntary internal radiation exposure screening programme.Primary and secondary outcome measuresInternal radiation exposure was evaluated using the whole-body counter (WBC) in the screening programme. Data from a food acquisition preference questionnaire administered to the participants were analysed and compared across the 5-year period after adjusting for covariates.ResultsOverall, 804 screening programmes were conducted with 579 participants during the study period. All participants had internal contamination levels below the detection limit of the WBC unit (220 and 250 Bq/body for Cs-134 and Cs-137, respectively). Based on the most conservative assumption, their maximum annual effective doses by Cs-134 and Cs-137 together were estimated at 16 µSv/year. Contrary to limited internal contamination risks and counter-dose initiatives by the government, a considerable number of pregnant women were still concerned about consuming potentially contaminated local food products when purchasing them at supermarkets between 2012 (78.4%) and 2015 (75.0%).ConclusionsHealth effects from post-accident internal radiation exposure were likely to be insignificant in pregnant women. National/local action is urgently needed to promote scientific understanding in pregnant women regarding limited internal exposure risks from local food products in the market. However, few mothers chose to participate in the internal radiation exposure screening programme, and thus, caution is required in interpreting the results of analyses.


2019 ◽  
Vol 48 (1) ◽  
pp. 46-52 ◽  
Author(s):  
Fathima Minisha ◽  
Mahmoud Mohamed ◽  
Dina Abdulmunem ◽  
Shaza El Awad ◽  
Mahmoud Zidan ◽  
...  

AbstractObjectivesTo explore the influence of ambient temperature and humidity on significant bacteriuria (SB) and urinary bacterial isolates in pregnant women.MethodsA retrospective observational study was conducted in the sole tertiary-care hospital in Doha, Qatar. A sample of 1588 pregnant women delivering between June 2012 and March 2013 was randomly selected. Meteorological variables including ambient average daily temperature and humidity were sourced from online meteorological data, and patient information such as demographic data, urine culture results and bacterial isolates were collected from patient files. The receptor operative curve (ROC) analysis was used to determine the cutoff for temperature and humidity. Statistical analyses of associations between SB and bacterial isolates with respect to the ambient temperature and humidity were performed using Pearson’s correlation, the chi-square (χ2) test and the Kruskal-Wallis test.ResultsOf the 21.24% positive cultures, 11.25% had SB. SB showed a significant strong positive (r = +0.677, n = 17, P = 0.003) and moderate negative (r = −0.587, n = 17, P = 0.013) correlation with average monthly temperature and humidity, respectively, with doubling of rates noted with temperatures ≥35°C (11.3% vs. 3.6%; P < 0.0001) and humidity ≤50% (10.6% vs. 3.2%; P < 0.0001). Escherichia coli and Group B Streptococcus (GBS) were the most common isolates.ConclusionThis is the first study in this region that demonstrates maternal risk with SB, with ambient temperatures of ≥35°C and humidity ≤50%. The effect of these variables on the growth of various urinary bacteria has also been shown.


Author(s):  
Shreetoma Datta ◽  
Sonali Jitendra Ingole ◽  
Jitendra R Ingole

Introduction: Pregnant women have also been affected globally due to the Coronavirus Disease 2019 (COVID-19) pandemic. As foeto-maternal unit is involved, hence it is important to know possible manifestations and outcome of COVID-19 affected pregnant women. The findings of the study can be a guide for betterment of COVID-19 affected antenatal patients care. Aim: To find the outcome of pregnancies affected by the COVID- 19 infection of the Antenatal care (ANC) patients who presented to the tertiary care hospital in terms of laboratory parameters, treatment of the infection, mode of delivery, adverse outcome if and presence of documented infection in newborn. Materials and Methods: This was a retrospective observational study done from May 2020 to December 2020 conducted on the admitted pregnant women to the tertiary care hospital who tested positive for the COVID-19 virus were included in the study. Data collection (symptoms, reports and treatment) from these pregnant COVID-19 positive patients was done. Patients who were discharged before delivery were contacted telephonically and were asked the relevant information. Results: During the study period, total 1150 COVID-19 positive patients were admitted to the hospital. Amongst these, there were 441 female patients including pregnant and non pregnant women. Amongst the 441 COVID-19 infected female patients, 20 were pregnant. Majority of the patients were in the age group of 21-30 years. An 85% of women were in their third trimester at the time of admission. Pre-eclampsia and Hypothyroidism were the major co-morbidities observed. Six maternal Intensive Care Unit (ICU) admissions were noted. Breathlessness was the main symptom seen followed by sore throat, fever and cough. Previous Lower Segment Caesarean Section (LSCS) and foetal distress were cited as the main reasons for undergoing LSCS. No vertical transmission of virus was seen in the study. There were two neonatal ICU admission. Low Molecular Weight Heparin (LMWH) was administered to 33% patients. Fifty percent of the patients were prescribed steroids. Conclusion: Advanced gestational age, pre-eclampsia, hypothyroidism, elevated levels of d-dimer, Neutrophil/Lymphocyte (NL) ratio and C-reactive protein were seen as the main findings. Mother to child transmission was not observed in this study.


PLoS ONE ◽  
2020 ◽  
Vol 15 (7) ◽  
pp. e0236130
Author(s):  
Masaki Tago ◽  
Naoko E. Katsuki ◽  
Yoshimasa Oda ◽  
Eiji Nakatani ◽  
Takashi Sugioka ◽  
...  

2012 ◽  
Vol 32 (S 01) ◽  
pp. S39-S42 ◽  
Author(s):  
S. Kocher ◽  
G. Asmelash ◽  
V. Makki ◽  
S. Müller ◽  
S. Krekeler ◽  
...  

SummaryThe retrospective observational study surveys the relationship between development of inhibitors in the treatment of haemophilia patients and risk factors such as changing FVIII products. A total of 119 patients were included in this study, 198 changes of FVIII products were evaluated. Results: During the observation period of 12 months none of the patients developed an inhibitor, which was temporally associated with a change of FVIII products. A frequent change of FVIII products didn’t lead to an increase in inhibitor risk. The change between plasmatic and recombinant preparations could not be confirmed as a risk factor. Furthermore, no correlation between treatment regimens, severity, patient age and comorbidities of the patients could be found.


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