Antioxidant properties of methanolic extracts from Diospyros mespiliformis (jackal berry), Flacourtia indica (Batoka plum), Uapaca kirkiana (wild loquat) and Ziziphus mauritiana (yellow berry) fruits

Diabetes mellitus is a serious health problem worldwide that has adverse and long-lasting consequences for individuals, families, and communities. Hence, this study sought to investigate the inhibitory potential of rosemary extracts on key-enzymes related to diabetes such as α-amylase and pancreatic lipase activities, as well as to assess their antioxidant properties in vitro. The IC50 values of Rosemary essential oil, ethyl acetate and methanolic extracts against α-amylase were 28.36, 34.11 and 30.39 µg/mL respectively, and those against pancreatic lipase were 32.25, 36.64 and 34.07 µg/mL, suggesting strong anti-diabetic and anti-obesity effects of Rosemary. The methanolic extract was found to be the highest in levels of phenolic (282.98 µgGAE/mg extract) and flavonoids (161.05 µg QE /mg extract) contents as well as in the antioxidant activity (IC50 = 15.82 µg/mL) as compared to other extracts ethyl acetate (IC50 = 32.23 µg/mL) and essential oil (IC50 = 96.12 µg/mL).Antioxidant efficacy of Rosemary extracts has been estimated in the stabilization of sunflower oil (SFO) at three different concentrations, i.e. 200 (SFO-200), 500 (SFO-500) and 1000 ppm (SFO-1000). Results showed the highest efficiency of SFO-1000.The results obtained in this study demonstrated for the first time that Rosemary is a potent source of natural inhibitors of α-amylase and pancreatic lipase with powerful antioxidants proprieties that might be used in the food stabilization and the prevention of diabetes and obesity complications as a complementary pharmacological drug.

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Comparison of Morphological, Antidiabetic and Antioxidant Properties of Goji Fruits

Acta Universitatis Cibiniensis Series E Food Technology ◽

10.2478/aucft-2020-0001 ◽

2020 ◽

Vol 24 (1) ◽

pp. 1-14

Author(s):

Arleta Kruczek ◽

Ireneusz Ochmian ◽

Marcelina Krupa-Małkiewicz ◽

Sabina Lachowicz

Keyword(s):

Antioxidant Activity ◽

Positive Impact ◽

Antioxidant Properties ◽

Total Content ◽

Point Of View ◽

Bioactive Substances ◽

Health Promoting ◽

Berry Fruits ◽

North Western ◽

Nitrite Content

AbstractThere is a growing public interest in fruits labeled as „superfood” (functional food). A “superfood” should have a high content of bioactive substances with a positive impact on human health. Seven different cultivars of goji berry fruits (Lycium chinense Mill.) grown in north-western Poland were evaluated for its physicochemical parameters, antidiabetic and antioxidant activity, and polyphenol content. The length of 1-year-old shoots ranged from 36 cm (‘Big Lifeberry’) to 82 cm (‘Korean Big’). Cultivars from the group of Big were characterized by the biggest fruits (17.3-24.2 mm) with the greatest weight of 100 fruits (96.7122.1 g). ‘Big Lifeberry’ contained high amounts of L-ascorbic acid (408 mg 1000/g) and provitamin A (190 mg 1000/g) and showed high antidiabetic (α-amylase IC50=33.4 mg/mL; α-glucosidase IC50=9.9 mg/mL) and antioxidant activity (ABTS·+ 6.21 and FRAP 5.58 mmol T/100 g). ‘Big Lifeberry’ was also characterized by a high total content of polyphenols (43.64 mg 100/g). Furthermore, the nitrite content in all the cultivars tested was at a relatively low level. Among the examined cultivars, the most attractive one concerning the consumers’ point of view of the size, weight and high content of health-promoting compounds is ‘Big Lifeberry’.

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EVALUATION OF HYPOGLYCAEMIC, HYPOLIPIDAEMIC AND NON TOXIC EFFECT OF HYDRO-METHANOLIC EXTRACTS OF ZIZIPHUS MAURITIANA, ZIZIPHUS SPINA CHRISTI FRUIT AND GLIBENCLAMIDE ON ALLOXAN INDUCED DIABETIC RATS

Journal of Drug Delivery and Therapeutics ◽

10.22270/jddt.v8i3.1711 ◽

2018 ◽

Vol 8 (3) ◽

Author(s):

Salisu M Abubakar ◽

Sufyan A Umar ◽

Idoko Alexander ◽

Nura Abubakar ◽

Mansurah A Abdulazeez ◽

...

Keyword(s):

Toxic Effect ◽

Diabetic Rats ◽

Ziziphus Mauritiana ◽

Methanolic Extracts

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Antioxidant Capacity and the Correlation with Major Phenolic Compounds, Anthocyanin, and Tocopherol Content in Various Extracts from the Wild EdibleBoletus edulisMushroom

BioMed Research International ◽

10.1155/2013/313905 ◽

2013 ◽

Vol 2013 ◽

pp. 1-11 ◽

Cited By ~ 30

Author(s):

Emanuel Vamanu ◽

Sultana Nita

Keyword(s):

Antioxidant Capacity ◽

Antioxidant Properties ◽

Reducing Power ◽

Ethanolic Extract ◽

Edible Mushroom ◽

Tocopherol Content ◽

Hot Water ◽

Antioxidant Compounds ◽

Methanolic Extracts ◽

Freeze Dried

Boletus edulisis a wild edible mushroom habitually consumed by rural populations. Ethanolic and methanolic extracts was obtained in cold and hot water from dried fruit bodies. The antioxidant activity of freeze-dried extracts fromB. eduliswere investigated using free radicals scavenging activity, reducing power, metal chelating effect, inhibition of lipid peroxidation, and the identification of antioxidant compounds. The levels of different compounds with antioxidant properties were higher in alcoholic extracts compared with aqueous extracts. Rosmarinic acid was the major phenolic compound, it being identified in a concentration between7±0.23and56±0.15 mg/100 g extract. A positive correlation between the content of total phenols, flavonoids, anthocyanins, and tocopherols, and the antioxidant capacity of the extracts was determined. The results showed that the ethanolic extract of Romanian wild mushroomB. edulisrepresents a natural source of functional compounds.

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Chelating and antioxidant activity of lignans from Chilean woods (Cupressaceae)

Holzforschung ◽

10.1515/hf.2009.123 ◽

2009 ◽

Vol 63 (5) ◽

Cited By ~ 8

Author(s):

César Donoso-Fierro ◽

José Becerra ◽

Evelyn Bustos-Concha ◽

Mario Silva

Keyword(s):

Antioxidant Activity ◽

Fungicidal Activity ◽

Extracellular Enzymes ◽

Antioxidant Properties ◽

Degradation Process ◽

Saprophytic Fungi ◽

Metal Chelating ◽

Methanolic Extracts ◽

Fitzroya Cupressoides

Abstract Wood species resistant to biodegradation by fungi contain phenolic compounds with proven fungicidal activity. Saprophytic fungi are able to colonize wood and later begin to break down its polymeric components through metal-dependent reactions. These generate free radicals at the onset of the degradation process. Later on, extracellular enzymes are active that use metallic cofactors. Five lignans were isolated from the methanolic extracts of the Chilean heartwoods (Austrocedrus chilensis, Fitzroya cupressoides, and Pilgerodendron uviferum) belonging to the Cupressaceae: isotaxiresinol, secoisolariciresinol, isolariciresinol, didemethylmatairesinol, and matairesinol. Their structures were determined spectroscopically. The antioxidant activity of the methanolic extracts and the isolated compounds was determined in vitro against the radical 1,1-diphenyl-2-picrylhydrazyl (DPPH) and their iron-chelating capacity was evaluated by the Chrome Azurol S assay. All isolated methanolic extracts and lignans exhibited antioxidant activity against DPPH and Fe-chelating capacity with values greater than 87%. This may be interpreted that the antioxidant properties and metal-chelating capacity of these compounds have a protective effect on the wood of these species when exposed to attacks by saprophytic fungi.

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Antioxidant properties of methanolic extracts from

Food Chemistry ◽

10.1016/j.foodchem.2004.10.043 ◽

2005 ◽

Vol 93 (4) ◽

pp. 641-649 ◽

Cited By ~ 46

Author(s):

J MAU ◽

S TSAI ◽

Y TSENG ◽

S HUANG

Keyword(s):

Antioxidant Properties ◽

Methanolic Extracts

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Antioxidant and cytotoxic activity of stems of Smilax zeylanica in vitro

Journal of Basic and Clinical Physiology and Pharmacology ◽

10.1515/jbcpp-2014-0114 ◽

2015 ◽

Vol 26 (5) ◽

Cited By ~ 2

Author(s):

Mohammad Nasir Uddin ◽

Taksim Ahmed ◽

Sanzida Pathan ◽

Md. Mamun Al-Amin ◽

Md. Sohel Rana

Keyword(s):

Petroleum Ether ◽

Methanolic Extract ◽

Antioxidant Properties ◽

In Vitro Assays ◽

Dpph Assay ◽

Cytotoxic Potential ◽

Phytochemical Study ◽

Methanolic Extracts ◽

Standard Procedures

AbstractPlant-derived phytochemicals consisting of phenols and flavonoids possess antioxidant properties, eventually rendering a lucrative tool to scavenge reactive oxygen species. This study was carried out to evaluate in vitro antioxidant and cytotoxic potential of methanolic extract and petroleum ether extracts ofPhytochemical screening was done following standard procedures. Antioxidant activity was tested using several in vitro assays, viz., 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay, NO assay, HPreliminary phytochemical study revealed the presence of flavonoids and glycosides in both extracts. Methanolic extract was found to possess stronger antioxidant potential than petroleum ether extracts in all assays. The ICThese findings demonstrate that methanolic extracts could be considered as potential sources of natural antioxidant, whereas petroleum ether extracts could be explored for promising anticancer molecules.

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