Characterization of the individual glucose uptake systems ofLactococcus lactis: mannose-PTS, cellobiose-PTS and the novel GlcU permease

A Multipoint Diffraction Strain Sensor (MISS) with the novel feature of simultaneous strain measurement at multiple points is characterized. Unlike conventional interferometry based systems, this patented sensor uses principles of diffraction to directly measure strain at large number of points. In this sensor, a high-frequency diffraction grating is illuminated by two symmetric laser beams and the diffracted beams are sampled on a CCD camera via a micro-lens array into an array of dots. The shift of the individual dots is sensed and strains or rigid body tilt are calculated directly. This novel technique is expected to be very valuable in numerous industrial applications.

Download Full-text

Species Thinking Without Agency: The Afterlife of Slavery, Clones, and Blurring Subject and Object in the Anthropocene

Orbit Writing Around Pynchon ◽

10.20919/exs.11.2021.310 ◽

2021 ◽

Vol 11 (1) ◽

pp. 23-45

Author(s):

Joey Song

Keyword(s):

Climate Change ◽

Nineteenth Century ◽

Political Rhetoric ◽

The Novel ◽

Kazuo Ishiguro ◽

The Earth ◽

The Individual ◽

And Control ◽

Afterlife Of Slavery

The overwhelming scale of climate change demands new ways of bridging national, cultural, and taxonomic differences. However, ecocritical frameworks that emphasise non-human agency in an attempt to make human individuals empathise with other people, other species, and the earth are haunted by the tenacious spectre of nineteenth-century classical liberalism’s characterization of personhood through specious, fragile dichotomies that can largely fall under the general rubric of agency versus determinism. The putatively opposed terms of these binaries are malleable, and control of their designation is a key element of control societies. Contemporary scholarship has identified several ways subjects bleed into objects, but, even though the ‘individual’ should theoretically collapse under its own ontological pressure in our current biopolitical age, neoliberalism largely holds onto classical liberalism’s central dogma of a person as an agential individual. I analyse the novel Never Let Me Go (2005) by Kazuo Ishiguro and its critical analyses to show how the plight to recognise agency is a prison of analysis that upholds an ideal of the individual as the bastion of personhood. As seen through the afterlife of slavery post-emancipation, those in power can discursively recognise the humanity in people formerly designated 'things' while still perpetuating systematic exploitation and dehumanisation. The metric of ‘agency’ as a unit of hope is an epistemic barrier to effective political rhetoric regarding climate change and species thinking.

Download Full-text

FUNKCIJA SELEKCIJE, KARAKTERIZACIJE I KONSTELACIJE LIKOVA U ROMANU VOLFGANGA HERNDORFA „ČIK“

Nasledje Kragujevac ◽

10.46793/naskg2149.303p ◽

2021 ◽

Vol 18 (49) ◽

pp. 303-320

Author(s):

Ivana Pajić ◽

Keyword(s):

Developmental Process ◽

Methodological Approach ◽

The Novel ◽

Social Image ◽

Award Winning ◽

Self Development ◽

The Subject ◽

The Individual ◽

Selection Of

The subject of the present work is Wolfgang Herrndorf’s award-winning youth novel Tsch- ick (i.e. “German Youth Literature Prize” (2011) and “Clemens Brentano Prize” (2012)). The novel, released in 2010, has sold more than two million copies to date and has been translated into more than 25 languages. In the novel, the story is told by Maik Klingenberg, a fourteen- year-old teenager who is left devastated by the surrounding circumstances and his outsider position before the summer holidays, but through his friendship with Tschick (during the summer holidays) experiences a solution and development process that changes his view of the world and his positioning to his environment and to himself in a positive way. The main focus of the work lies on the (explicit and implicit) character selection, characterization and constellation in the text. The methodological approach to textual analysis is based on insights from narratology, sociology and psychoanalysis. After a theoretical-introductory part, the text-analytical part begins with the selection of the staff of the fictitious world depicted in the novel and shows that the author’s novel gives a pluralistic-heterogeneous-inter- or transcul- tural social image of the German capital Berlin and its (wider) environment. In the following chapter of the work, the introductory characterization of the main character and the related figure constellations will be discussed in more detail. It is shown that Herrndorf uses these constellations to address the complex interrelation between the individual and various col- lective identities, such as those into which the subject is born (Maik’s parents), and those to whom the subject belongs based on the present circumstances of life (Maik’s teacher and the other students of the school). The focus of analysis of the following part lies on those figure constellations that have arisen as a result of Maik’s escape from the structures crushing him (Maik’s voluntary social interactions and friendly ties) and by which the author refers to the dynamic constitution of personal identity, of which the developmental process defies static defining and reveals the possibility of self-change and self-development. Based on the pre- viously given text analysis, the last part of the thesis gives a conclusion corresponding to the analysis results.

Download Full-text

Characterization of the novel aspartic proteinases, BACE and BACE2

Neuroscience Research ◽

10.1016/s0168-0102(00)81592-8 ◽

2000 ◽

Vol 38 ◽

pp. S124

Author(s):

S Kametaka

Keyword(s):

The Novel ◽

Aspartic Proteinases

Download Full-text

Margaret Mahy: An Adlerian Reading

International Research in Children s Literature ◽

10.3366/ircl.2008.0006 ◽

2008 ◽

Vol 1 (2) ◽

pp. 187-199

Author(s):

KATHRYN WALLS

Keyword(s):

Young Female ◽

The Other ◽

Individual Psychology ◽

The Novel ◽

Alfred Adler ◽

Female Protagonists ◽

Magical Power ◽

Margaret Mahy ◽

The Individual

According to the ‘Individual Psychology’ of Alfred Adler (1870–1937), Freud's contemporary and rival, everyone seeks superiority. But only those who can adapt their aspirations to meet the needs of others find fulfilment. Children who are rejected or pampered are so desperate for superiority that they fail to develop social feeling, and endanger themselves and society. This article argues that Mahy's realistic novels invite Adlerian interpretation. It examines the character of Hero, the elective mute who is the narrator-protagonist of The Other Side of Silence (1995) , in terms of her experience of rejection. The novel as a whole, it is suggested, stresses the destructiveness of the neurotically driven quest for superiority. Turning to Mahy's supernatural romances, the article considers novels that might seem to resist the Adlerian template. Focusing, in particular, on the young female protagonists of The Haunting (1982) and The Changeover (1984), it points to the ways in which their magical power is utilised for the sake of others. It concludes with the suggestion that the triumph of Mahy's protagonists lies not so much in their generally celebrated ‘empowerment’, as in their transcendence of the goal of superiority for its own sake.

Download Full-text

The Free Responsible Action of the Individual

10.1093/oso/9780198824176.003.0014 ◽

2018 ◽

Author(s):

Michael P. DeJonge

Keyword(s):

The Novel ◽

Extreme Situation ◽

The Third ◽

Third Phase ◽

Responsible Action ◽

Action Type ◽

Two Phases ◽

The Individual ◽

The Church

If, as Chapter 12 argues, much of Bonhoeffer’s resistance thinking remains stable even as he undertakes the novel conspiratorial resistance, what is new in his resistance thinking in the third phase? What receives new theological elaboration is the resistance activity of the individual, which in the first two phases was overshadowed by the resistance role played by the church. Indeed, as this chapter shows, Bonhoeffer’s conspiratorial activity is associated with what he calls free responsible action (type 6), and this is the action of the individual, not the church, in the exercise of vocation. As such, the conspiratorial activity is most closely related to the previously developed type 1 resistance, which includes individual vocational action in response to state injustice. But the conspiratorial activity differs from type 1 resistance as individual vocational action in the extreme situation.

Download Full-text

Separation and Characterization of Standard Propoxyphene Diastereomers and Their Determination in Pharmaceutical and Illicit Preparations

Journal of AOAC INTERNATIONAL ◽

10.1093/jaoac/64.4.875 ◽

1981 ◽

Vol 64 (4) ◽

pp. 875-883

Author(s):

Shiv K Soni ◽

Daniel Van Gelder

Keyword(s):

High Pressure ◽

Optical Isomers ◽

Gold Chloride ◽

Melting Points ◽

Eutectic Melting ◽

Racemic Mixtures ◽

The Individual ◽

Isomeric Mixtures ◽

Asymmetric Carbon

Abstract Due to the existence of 2 asymmetric carbon atoms in: the propoxyphene molecule, there are 4 diastereomers: alpha dextro, alpha levo, beta dextro, and beta levo. Only α-d-propoxyphene is included under the federal Controlled Substances Act. Baseline separations of propoxyphene from various incipients (aspirin, caffeine, phenacetin, and acetaminophen) present in pharmaceutical and illicit preparations, and between the alpha and beta diastereomers, were achieved by high pressure liquid chromatography. The column eluant was collected and propoxyphene was extracted. The optical isomers were differentiated and characterized by melting points and by chemical microcrystalline tests. Using hot stage thermomicroscopy, the eutectic melting points of binary isomeric mixtures of propoxyphene bases and salts were found to be depressed about 10° and 15-30°C, respectively, below the individual isomer melting points. The characteristic microcrystals formed with the alpha racemic mixtures by using a glycerin-aqueous gold chloride reagent were not produced by the beta racemic mixtures.

Download Full-text

Does higher education properly prepare graduates for the growing artificial intelligence market? Gaps identification using text mining

Human Systems Management ◽

10.3233/hsm-211179 ◽

2021 ◽

pp. 1-13

Author(s):

Lamiae Benhayoun ◽

Daniel Lang

Keyword(s):

Artificial Intelligence ◽

Natural Language Processing ◽

Text Mining ◽

Natural Language ◽

Language Processing ◽

Academic Training ◽

Market Requirements ◽

Job Advertisements ◽

The Individual

BACKGROUND: The renewed advent of Artificial Intelligence (AI) is inducing profound changes in the classic categories of technology professions and is creating the need for new specific skills. OBJECTIVE: Identify the gaps in terms of skills between academic training on AI in French engineering and Business Schools, and the requirements of the labour market. METHOD: Extraction of AI training contents from the schools’ websites and scraping of a job advertisements’ website. Then, analysis based on a text mining approach with a Python code for Natural Language Processing. RESULTS: Categorization of occupations related to AI. Characterization of three classes of skills for the AI market: Technical, Soft and Interdisciplinary. Skills’ gaps concern some professional certifications and the mastery of specific tools, research abilities, and awareness of ethical and regulatory dimensions of AI. CONCLUSIONS: A deep analysis using algorithms for Natural Language Processing. Results that provide a better understanding of the AI capability components at the individual and the organizational levels. A study that can help shape educational programs to respond to the AI market requirements.

Download Full-text