Transmission of hepatitis C virus by needle-stick injury in community settings

2007 ◽  
Vol 22 (11) ◽  
pp. 1882-1885 ◽  
Author(s):  
Paul S Haber ◽  
Margaret M Young ◽  
Lloyd Dorrington ◽  
Andrew Jones ◽  
John Kaldor ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Needle Stick Injury ◽  
Community Settings ◽  
Needle Stick

scholarly journals PENULARAN PENYAKIT TERHADAP PERAWAT AKIBAT KECELAKAAN KERJA

2020 ◽  
Author(s):  
Azmal Umara Siregar
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Needle Stick Injury ◽  
Needle Stick ◽  
B Virus ◽  
Immunodeficiency Virus ◽  
Bloodborne Pathogen

Rumah sakit merupakan suatu tempat yang berisiko terjadinya cedera. Hal ini disebabkan karena berbagai kegiatan dirumah sakit sangat berhubungan dengan penyakit-penyakit berbahaya, prosedur kritis dengan alat atau benda tajam. WHO (1995) memperkirakan 10% petugas kesehatan mengalami injury benda tajam. Kecelakaan dalam bekerja dapat diakibatkan oleh kelalaian pekerja, bekerja melebihi batas kemampuan atau ergonomis yang buruk dalam bekerja. Dalam bidang kesehatan, kelalaian dalam bekerja bisa terjadi apa saja. Salah satunya adalah tertusuk jarum atau benda tajam di rumah sakit. Jarum suntik dan alat medis yang tajam merupakan alat medis yang bersentuhan langsung dengan jaringan tubuh dan darah pasien. Tenaga kesehatan yang lalai dapat tertular melalui jarum suntik yang terkontaminasi cairan tubuh pasien yang terinfeksi. Petugas kesehatan berisiko terpapar darah dan cairan tubuh yang terinfeksi (bloodborne pathogen) yang dapat menimbulkan infeksi HBV (Hepatitis B Virus), HCV (Hepatitis C Virus) dan HIV (Human Immunodeficiency Virus) melalui berbagai cara, salah satunya melalui luka tusuk jarum atau yang dikenal dengan istilah Needle Stick Injury atau NSI (Hermana, 2006). Luka atau cidera akibat tertusuk jarum atau benda tajam lainnya merupakan hal yang sangat perlu diperhatikan. Apabila seorang petugas kesehatan tanpa sengaja terluka akibat tertusuk jarum yang sudah terkontaminasi cairan tubuh orang yang sakit maka beresiko terjadi penularan sekurang-kurangnya 20 patogen potensial. Dua patogen yang sangat berbahaya adalah Hepatitis B (HBV) dan Human Immunodefidiensy Virus (HIV). Hepatitis B (HBV) adalah infeksi pada hati atau liver. Penyakit ini sering ditemui dan penyebaran nya 100 kali lebih cepat dari HIV dan dapat menyebabkan kematian.

Simultaneous Transmission of Human Immunodeficiency Virus and Hepatitis C Virus from a Needle-Stick Injury

1997 ◽  
Vol 336 (13) ◽  
pp. 919-922 ◽  
Author(s):  
Renée Ridzon ◽  
Kathleen Gallagher ◽  
Carol Ciesielski ◽  
Eric E. Mast ◽  
Michael B. Ginsberg ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Needle Stick Injury ◽  
Needle Stick ◽  
Immunodeficiency Virus ◽  
Simultaneous Transmission

36 Induction of hepatitis C virus specific T cells by needle stick injury in the absence of HCV-viremia

Hepatology ◽  
2003 ◽  
Vol 38 ◽  
pp. 173-173 ◽  
Author(s):  
A KUBITSCHKE ◽  
M BAHR ◽  
N ASLAN ◽  
C SARAZZIN ◽  
H TILLMANN ◽  
...  
Keyword(s):  
T Cells ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Needle Stick Injury ◽  
Needle Stick

Induction of hepatitis C virus (HCV)-specific T cells by needle stick injury in the absence of HCV-viraemia

2007 ◽  
Vol 37 (1) ◽  
pp. 54-64 ◽  
Author(s):  
A. Kubitschke ◽  
M. J. Bahr ◽  
N. Aslan ◽  
C. Bader ◽  
H. L. Tillmann ◽  
...  
Keyword(s):  
T Cells ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Needle Stick Injury ◽  
Needle Stick

scholarly journals Change in hepatitis C virus positivity among needle-stick injury source patients: a 10-year experience in a Japanese tertiary hospital

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Kazuya Okushin ◽  
Rie Suzuki ◽  
Takeya Tsutsumi ◽  
Koh Okamoto ◽  
Kazuhiko Ikeuchi ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Liver Diseases ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Hcv Rna ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Needle Stick

Abstract Background As a blood-borne pathogen, hepatitis C virus (HCV) has long been a major threat associated with needle-stick injuries (NSIs) mainly because no vaccine is available for HCV. Following an NSI, we usually test the source patient for HCV antibody (HCV-Ab). Since HCV-Ab positivity does not necessarily indicate current infection, HCV RNA is further examined in patients positive for HCV-Ab. Direct-acting antivirals (DAAs) have enabled us to treat most HCV-infected patients; therefore, we speculate that the rate of HCV RNA positivity among HCV-Ab-positive patients decreased after the emergence of DAAs. This cross-sectional study was performed to investigate the change in the actual HCV RNA positivity rate in source patients before and after the interferon (IFN)-free DAA era. Methods This was a cross-sectional study of NSI source patients at a tertiary academic hospital in Japan from 2009 to 2019. IFN-free DAA regimens were first introduced in Japan in 2014. Accordingly, we compared HCV status of NSI source patients that occurred between 2009 and 2014 (the era before IFN-free DAAs) with those that occurred between 2015 and 2019 (the era of IFN-free DAAs) in a tertiary care hospital in Japan. Results In total, 1435 NSIs occurred, and 150 HCV-Ab-positive patients were analyzed. The proportion of HCV RNA-positive patients significantly changed from 2009 through 2019 (p = 0.005, Cochran–Armitage test). Between 2009 and 2014, 102 source patients were HCV-Ab-positive, 78 of whom were also positive for HCV RNA (76.5%; 95%CI, 67.4–83.6%). Between 2015 and 2019, 48 patients were HCV-Ab-positive, 23 of whom were also positive for HCV RNA (47.9%; 95%CI, 34.5–61.7%; p = 0.0007 compared with 2009–2014). In the era of IFN-free DAAs, 9 of 23 HCV RNA-negative patients (39.1%) and 2 of 22 HCV RNA-positive patients (9.1%) were treated with an IFN-free combination of DAAs (p = 0.0351). Regarding the departments where NSIs occurred, HCV RNA-negative patients were predominant in departments not related to liver diseases in the era of IFN-free DAAs (p = 0.0078, compared with 2009–2014). Conclusions Actual HCV RNA positivity in source patients of NSIs decreased after the emergence of IFN-free DAAs. IFN-free DAAs might have contributed to this reduction, and HCV RNA-negative patients were predominant in departments not related to liver diseases in the era of IFN-free DAAs.

scholarly journals FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KECELAKAAN KERJA TERTUSUK JARUM SUNTIK ATAU BENDA TAJAM LAINNYA PADA PERAWAT DI RSUD LEUWILIANG KABUPATEN BOGOR TAHUN 2018

PROMOTOR ◽  
2019 ◽  
Vol 2 (2) ◽  
pp. 163
Author(s):  
Sylvia Puspitasari ◽  
Supriyanto . ◽  
Rubi Ginanjar
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Random Sampling ◽  
Simple Random Sampling ◽  
P Value ◽  
Needle Stick Injury ◽  
Cross Sectional ◽  
B Virus ◽  
Immunodeficiency Virus

<p>Petugas kesehatan berisiko tertular penyakit dari darah/cairan tubuh (bloodborne pathogen) melalui berbagai cara, salah satunya melalui luka tusuk jarum atau yang dikenal dengan istilah Needle Stick Injury (NSI). Risiko yang dapat terjadi jika tertusuk jarum dapat menimbulkan infeksi HBV<br />(Hepatitis B Virus), HCV (Hepatitis C Virus) dan HIV (Human Immunodeficiency Virus). Tujuan dari penelitian ini adalah untuk mengetahui faktor-faktor yang berhubungan dengan kecelakaan kerja tertusuk jarum suntik atau benda tajam lainnya pada Perawat di RSUD Leuwiliang Kabupaten Bogor tahun 2018. Penelitian ini menggunakan desain studi cross sectional. Teknik pengambilan sampel menggunakan simple random sampling dengan jumlah responden sebanyak 71 orang. Pengambilan data dalam penelitian ini menggunakan kuesioner dan menganalisis data dengan uji statistik chisquare<br />menggunakan perangkat lunak aplikasi statistic (SPSS 16). Hasil penelitian menunjukkan bahwa tidak ada hubungan antara tindakan tidak aman (p-value = 0,461), kondisi tidak aman (p-value = 0,301, masa kerja (p-value = 0,757), pengetahuan (p-value = 0,190), pengawasan (p-value = 0,090)<br />dengan kecelakaan kerja tertusuk jarum suntik atau benda tajam lainnya. Sedangkan untuk variabel lainnya, ada hubungan antara keterampilan (p-value = 0,010) OR = 0,237 (95% CI: 0,085-0,662), pelatihan (p value = 0,022) OR = 3,566 (95% CI: 1,313-9,688) dengan kecelakaan kerja tertusuk<br />jarum suntik atau benda tajam lainnya. Kesimpulan penelitian ini adalah kurangnya keterampilan dan pelatihan mempengaruhi perawat dalam kecelakaan kerja, karena keterampilan dan pelatihan dibutuhkan seseorang dalam setiap pekerjaan untuk meningkatkan kemampuan dan keahliannya<br />sehingga mampu menyelesaikan tugas dengan baik dan dapat terhindar dari risiko kecelakaan kerja</p>

Risk of needle-stick injuries in the transmission of hepatitis C virus in hospital personnel

1992 ◽  
Vol 16 (1-2) ◽  
pp. 56-58 ◽  
Author(s):  
M. Eugenia Hernandez ◽  
Miguel Bruguera ◽  
Trinidad Puyuelo ◽  
José M. Barrera ◽  
José M. Sanchez Tapias ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Hospital Personnel ◽  
Needle Stick ◽  
Needle Stick Injuries

scholarly journals Seroprevalence of Hepatitis C Virus among Health Care Workers

1970 ◽  
Vol 18 (1) ◽  
pp. 70-74 ◽  
Author(s):  
MR Uddin ◽  
MMS Islam ◽  
MZ Hossain ◽  
MN Sarker ◽  
ASM Salimullah ◽  
...  
Keyword(s):  
Health Care ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Health Care Workers ◽  
Kidney Diseases ◽  
Public Health Problem ◽  
Needle Stick Injury ◽  
Major Public Health Problem ◽  
Key Words Hepatitis C ◽  
Care Workers

Context: Hepatitis C virus is one of the leading causes of liver disease and represents a major public health problem. It is a common cause of cirrhosis and hepatocellular carcinoma (HCC) as well as the most common reason for liver transplantation. Methods: A cross sectional study was carried out during the period of April 2007 to April 2008 among health care workers including phlebotomists, dialysis staffs and laboratory personnel handling blood and blood products. Total 200 health care workers from phlebotomists working at one stop collection centre of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka Medical College Hospital (DMCH), Dialysis staff working at haemodialysis units of BSMMU, Bangladesh Institute of Rehabilitation for Diabetes, Endocrine & Metabolic Diseases (BIRDEM), DMCH, National Institute of Kidney Diseases & Urology (NIKDU) had at least more than one year working exposure was enrolled in this study. After taking informed written consent detailed history was taken, clinical examination was done. 0.3 ml of venous blood was collected from each patient and tested for anti HCV by commercial kit, confirmed by ELISA method. Result: Among 200 patients majority (55.5%) of patients were below 30 years of age and there was equal prevalence among male and female. Out of 200 health care workers 1% was found to be anti HCV positive. All positive patient had duration of exposure of >5 years and had history of needle stick injury. Key words: Hepatitis C virus; seroprevalence; health care workers. DOI: 10.3329/jdmc.v18i1.6310 J Dhaka Med Coll. 2009; 18(1) : 70-74

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