PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL PROPERTIES OF ALLIUM ROSEUM L., A WILD EDIBLE SPECIES IN NORTH AFRICA

2011 ◽  
Vol 35 (3) ◽  
pp. 699-714 ◽  
Author(s):  
HANEN NAJJAA ◽  
SAMI ZOUARI ◽  
EMNA AMMAR ◽  
MOHAMED NEFFATI
Keyword(s):  
North Africa ◽  
Antibacterial Properties ◽  
Phytochemical Screening ◽  
Edible Species

scholarly journals Phytochemical Screening, Antioxidant and Antibacterial Activities of the Root Extract of Cyphostemma adenocaule (Steud. ex A. Rich.) Wild & R.B.Drumm

2021 ◽  
Vol 10 (2) ◽  
pp. 105-110
Author(s):  
Abdulbasit Haliru Yakubu ◽  
Mohammed Mustapha Mohammed ◽  
Abdulqadir Bukar Bababe ◽  
Hassan Yesufu Braimah
Keyword(s):  
Scientific Evidence ◽  
Antibacterial Properties ◽  
Plant Secondary Metabolites ◽  
Biological Properties ◽  
Chloroform Extract ◽  
Chemical Diversity ◽  
Root Extract ◽  
Moderate Activity ◽  
Phytochemical Screening ◽  
Test Organisms

Plant secondary metabolites have provided important bioactive principles for developing new lead compounds. Within their confinement, they exhibit unique chemical diversity, which influences their diverse biological properties. The Vitaceae family is known for its potent antioxidant and antibacterial phytoconstituents, among other biological properties. Cyphostemma adenocaule is one of the family members explored for its ethnomedicinal properties. This study undertook the evaluation of the phytochemical, antioxidant, and antibacterial properties of the root extract of Cyphostemma adenocaule. Preliminary phytochemical screening revealed the presence of flavonoids, alkaloids, carbohydrates & glycoside, saponins, and tannins. The methanol root extract had the highest activity in the DPPH assay, providing IC50 (50% inhibition) of 10.87µg/ml, followed by n-Hexane (IC50 74.10µg/ml) and chloroform (IC50 74.31µg/ml) extract. In the antibacterial assay, the chloroform extract was active against E. coli (24.00±0.15) and had moderate activity against Staph. aureus (12.5±0.18). The n-Hexane extract was completely inactive against the test organisms while the methanol extract showed poor activity against the test organisms. The present study adds to the existing literature on Cyphostemma adenocaule with scientific evidence into its biological properties.

scholarly journals Phytochemical Screening: Antioxidant and Antibacterial Properties of Potamogeton Species in Order to Obtain Valuable Feed Additives

2015 ◽  
Vol 64 (10) ◽  
pp. 1111-1123 ◽  
Author(s):  
Paul Lupoae ◽  
Victor Cristea ◽  
Daniela Borda ◽  
Mariana Lupoae ◽  
Gabriela Gurau ◽  
...  
Keyword(s):  
Antibacterial Properties ◽  
Feed Additives ◽  
Phytochemical Screening

scholarly journals Evaluation of the Antibacterial Properties of the Hydro-Ethanolic Leaf and Stembark of Psidium guajava (Myrtaceae) on Cariogenic and Periodontopathic Bacteria

2021 ◽  
pp. 34-49
Author(s):  
Fowedlung Ngufor Agafina ◽  
Ashu Michael Agbor ◽  
Fotsing Kwetche Pierre René ◽  
Tembe Fokunang Estella ◽  
Pilipili Charles ◽  
...  
Keyword(s):  
Bacterial Resistance ◽  
Periodontal Diseases ◽  
Financial Burden ◽  
Antibacterial Properties ◽  
Stem Bark ◽  
Psidium Guajava ◽  
Total Phenol Content ◽  
Phytochemical Screening ◽  
Coarse Powder ◽  
Periodontopathic Bacteria

Background: Caries and periodontal diseases are major public health problems. Due to increase in bacterial resistance to antibiotics, there is a need to promote the known potential of plants and search for new anti-infectious substances as therapeutic alternatives to antibiotics. Aims: This study was aimed at evaluating the antibacterial property of the hydro-ethanolic leaf and stem bark extracts of Psidium guajava on cariogenic and periodontopathic bacteria. Methodology: This was an experimental study that took place in the Laboratory of Chemistry and Microbiology (Clinique Universitaires des Montagne (CUM)) of Bangangté between January to June 2020. They were dried in shade for 3 weeks and ground to obtain a coarse powder. The dried powders were macerated for 72 hours in a water-ethanol mixture (30:70). Then, the phytochemical screening and quantification of the total polyphenol content followed. Microdilutions were used to determine the minimum inhibitory concentrations (MIC) of guava. Müller Hinton agar was used for obtaining the minimum bactericidal concentrations (MBC) and the determination of inhibition diameters of the bacteria. Results: Extraction yields of 17.36g and 42.55g were obtained for leaf and stem bark, respectively. The phytochemical screening revealed the presence of various secondary metabolites among which the total phenol content was quantified at 236.1878 and 255.7682 mg equivalent of gallic acid per gram for leaf and stem bark, respectively. The carious bacteria isolated were: Streptococcus mutans, Actinomycetes viscosus and Lactobacillus acidophilus.While, the periodontal bacteria were: Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum ,Tannerella forsythensis. The results obtained showed that the combined extracts of leaf and stem bark had an activity higher than that of the stem bark which in turn had a higher activity than the leaves.  Conclusion: Non-invasive independent predictors for screening esophageal varices may decrease medical as well as financial burden, hence improving the management of cirrhotic patients. These predictors, however, need further work to validate reliability.

scholarly journals Phytochemical Screening, Liver Toxicity and Antibacterial Properties of Aqueous and Ethanol Extracts of a Local Herbal Mixture “Aju Mbaise”

2020 ◽  
Vol 4 (6) ◽  
pp. 237-242
Author(s):  
Oprah Evbakhavbokun ◽  
◽  
Taidi Ekrakene ◽  
Ebakota Daniel ◽  
Frances Olisaka ◽  
...  
Keyword(s):  
Liver Toxicity ◽  
Antibacterial Properties ◽  
Phytochemical Screening ◽  
Herbal Mixture ◽  
Ethanol Extracts

scholarly journals Herbology, Antibacterial and Antihaemorrhagic Effect of Allium sativum Linn (Lilliaceae) Extracts against Bacterial Meningitis Pathogens

2021 ◽  
pp. 10-18
Author(s):  
Kokori Bajeh Tijani ◽  
Abdullahi Attah Alfa ◽  
O. D. Omotoso ◽  
Yahaya Junaidu ◽  
Umar Sabdat Unoyiza
Keyword(s):  
Bacterial Meningitis ◽  
Cardiac Glycosides ◽  
Antibacterial Properties ◽  
Scientific Basis ◽  
Sub Saharan Africa ◽  
Phytochemical Screening ◽  
Neurologic Disorders ◽  
Sub Saharan ◽  
Pharmacologically Active ◽  
Ethnomedicinal Uses

Bacterial Meningitis pathogen (BMP) causes cellular hemorrhagic sepsis, metabolic, endocrine and neurologic disorders in human systems. This burden of the disease is highest in the developing countries and especially in the immunity compromised rural populations in Sub-Saharan Africa. The A. sativum bulb extracts (JEAS, EEAS and AEAS) contain valuable pharmacologically active principles for antihaemorrhagic and antibacterial properties against bacterial meningitis pathogens. It extracts were evaluated in Wistar rats to provide scientific basis for ethnomedicinal uses. The phytochemical screening was conducted using standard method prescribed. Anti-haemorrhagic activity was evaluated using sterilized blade lancet to cut 2mm long and 2mm deep in the rat groin model. The coagulative effects of time were significantly at P<0.05 reduced by the bulb extracts applied as compared to that of the control. The phytochemical screening revealed the presence of alkaloids, cardiac glycosides, carbohydrates, flavonoids, saponins, steroids and tannins. The result of this study revealed that A. sativum bulb extracts possessed good secondary metabolites with bioactive principles, biological and pharmacological functions. This provide scientific basis for the plant in the management of haemorrhagic sepsis and infectious disease.

scholarly journals Suppression of Proinflammatory Cytokines by Etlingera alba (A.D.) Poulsen Rhizome Extract and Its Antibacterial Properties

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Rini Hamsidi ◽  
Wahyuni Wahyuni ◽  
Idin Sahidin ◽  
Evi Apriyani ◽  
Harsono Harsono ◽  
...  
Keyword(s):  
Antibacterial Properties ◽  
Chemical Constituent ◽  
Test Tube ◽  
Phytochemical Screening ◽  
Pharmacological Activities ◽  
E Coli ◽  
Edema Volume ◽  
Tnf Α ◽  
Cytokine Levels ◽  
Anti Inflammatory

Etlingera alba is one of the Etlingera plants that has not been studied intensively. Plants that belong to the same genus have similar constituents and pharmacological activities. Thus, we aim to investigate the chemical composition and pharmacological activities, namely, anti-inflammatory and antibacterial properties, of E. alba rhizome extract (EA). The chemical constituent was detected using the test tube method. The inflammatory model rats were obtained by inducing them with 1% carrageenan, and their palm edema volume and cytokine levels, namely, IL-6, IL-12, and TNF-α, were measured. Antibacterial activity was performed with broth microdilution. The phytochemical screening of EA was detecting alkaloids, flavonoids, tannins, steroids, and phenols. The EA has anti-inflammatory activity by reducing the palms’ edema volume and cytokine levels (IL-6, IL-12, and TNF-α), and the optimal concentration was 400 mg/kg body weight (BW). On the other hand, EA also exhibited antibacterial properties against E. coli and S. enterica. In conclusion, similar to other Etlingera plants, EA also demonstrates pharmacological activities, namely, anti-inflammatory and antibacterial properties.

scholarly journals Phytochemical Screening, Antioxidant and Antibacterial Activities of Pollen Extracts from Micromeria fruticosa, Achillea fragrantissima, and Phoenix dactylifera

Plants ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 676
Author(s):  
Omar Sadeq ◽  
Hamza Mechchate ◽  
Imane Es-safi ◽  
Mohamed Bouhrim ◽  
Fatima zahra Jawhari ◽  
...  
Keyword(s):  
Radical Scavenging ◽  
Antibacterial Properties ◽  
Male Flower ◽  
Phoenix Dactylifera ◽  
Antibacterial Activities ◽  
Total Phenolic ◽  
Phytochemical Screening ◽  
Antioxidant Power ◽  
Achillea Fragrantissima ◽  
Micromeria Fruticosa

Pollen is a male flower gametophyte located in the anthers of stamens in angiosperms and a considerable source of compounds with health protective potential. In the present work, phytochemical screening was carried out as well as analysis of the antioxidant and antibacterial properties of pollen extracts from Micromeria fruticosa, Achillea fragrantissima, and Phoenix dactylifera growing wild in Palestine. Phytochemical screening examined the total flavonol, flavone and phenolic content. The DPPH (1,2-Diphenyl-1-Picrylhydrazyl) and FRAP (ferric reducing antioxidant power) methods were used to assess antioxidant propriety, and disc diffusion, minimum inhibitory and bactericidal concentration tests were used to test the pollen extract’s antibacterial activity against multidrug-resistant (MDR) clinical isolates. The highest level of total phenolic was found in the extract of Micromeria fruticosa (56.78 ± 0.49 mg GAE (Gallic Acid Equivalent)/g). The flavone and flavonol content of samples ranged from 2.48 ± 0.05 to 8.03 ± 0.01 mg QE (Quercetin Equivalent)/g. Micromeria fruticosa pollen with IC50 values of 0.047 and 0.039 mg/mL in the DPPH and FRAP assays, respectively, showed the greatest radical scavenging action. In addition, this pollen showed a mild antibacterial action against the microorganisms studied, with MICs varying from 0.625 to 10 mg/mL and inhibition diameters ranging from 13.66 ± 1.5 to 16.33 ± 1.5 mm.

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