The Clinical Investigator as Fiduciary: Discarding a Misguided Idea

2005 ◽  
Vol 33 (3) ◽  
pp. 586-598 ◽  
Author(s):  
E. Haavi Morreim
Keyword(s):  
Clinical Research ◽  
Standard Care ◽  
Standard Treatment ◽  
Medical Community ◽  
Clinical Equipoise ◽  
Medical Patients ◽  
Research Subjects ◽  
Clinical Investigator ◽  
The People ◽  
The Relationship

One of the most important questions in the ethics of human clinical research asks what obligations investigators owe the people who enroll in their studies. Research differs in many ways from standard care - the added uncertainties, for instance, and the nontherapeutic interventions such as diagnostic tests whose only purpose is to measure the effects of the research intervention. Hence arises the question whether a physician engaged in clinical research has the same obligations toward research subjects that he owes his medical patients, or whether they differ in any fundamental way.Perhaps the most common answer is that the relationship is the same. Investigators, like physicians, are said to be fiduciaries of the volunteers who enroll in research trials. Each owes the best available medical care, which means that a physician can only justify enrolling his patient in research if the study meets the requirements of clinical equipoise, namely, that there is legitimate disagreement within the medical community as to whether the standard treatment or the investigational intervention is superior.

Pediatric Assent: Subject Protection Issues among Adolescent Females Enrolled in Research

2006 ◽  
Vol 34 (2) ◽  
pp. 451-459 ◽  
Author(s):  
Theresa O'Lonergan ◽  
John J. Zodrow
Keyword(s):  
Clinical Research ◽  
Randomized Clinical Trials ◽  
Ethical Issues ◽  
Pediatric Population ◽  
Medical Community ◽  
Research Subjects ◽  
Regulatory Requirements ◽  
Number Of Factors ◽  
Clinical Investigations ◽  
Scientific Attention

Randomized Clinical Trials (RCTs) in the medical community are generally lasting longer due to a number of factors, including an increase in the total volume of biomedical research, expanded federal regulatory requirements, and a rise in patient interest in participating as research subjects. Leading national and international initiatives promote clinical research in children. The primary impetus for these initiatives is the need for adequate data for clinical application of new products and treatment approaches in the pediatric population. Clinical investigations must maintain ethical conduct as an essential component of pediatric research.Ethical issues associated with clinical research in general have received prominent public and scientific attention. Of particular interest is informed consent, or assent, as applied to pediatrics. There is little practical guidance concerning pediatric assent from legal and ethical disciplines; the law has played only a small role in few cases.

Fiduciary Obligation in Clinical Research

2006 ◽  
Vol 34 (2) ◽  
pp. 424-440 ◽  
Author(s):  
Paul B. Miller ◽  
Charles Weijer
Keyword(s):  
Clinical Research ◽  
Recent Work ◽  
Legal Theory ◽  
Duty Of Care ◽  
Clinical Equipoise ◽  
Legal Norms ◽  
The Law ◽  
The Relationship

Bioethics is currently witnessing unprecedented debate over the moral and legal norms governing the conduct of clinical research. At the center of this debate is the duty of care in clinical research, and its most widely accepted specification, clinical equipoise. In recent work, we have argued that equipoise and cognate concepts central to the ethics of clinical research have been left unnecessarily vulnerable to criticism. We have suggested that the vulnerability lies in the conspicuous absence of an articulated foundation in moral and legal theory of the physician-researcher's duty of care to the patient-subject. We have repeatedly suggested that the requisite foundation is in the ethics of trust and the law of fiduciaries.Curiously, despite the absence of a published thorough exposition of our position, some have preemptively criticized our suggestion that the relationship between physician-researcher and patient-subject is fiduciary. Others have offered their own accounts of the implications of fiduciary law for the relationship.

scholarly journals KEARIFAN LOKAL DALAM MEMBANGUN KERUKUNAN ISLAM DAN HINDU DI DESA ADAT KUTA BADUNG

2021 ◽  
Vol 31 (2) ◽  
pp. 237
Author(s):  
Yantos Yantos ◽  
Putriana Putriana
Keyword(s):  
Social Integration ◽  
Qualitative Method ◽  
Community Leaders ◽  
Integration Theory ◽  
Religious Leaders ◽  
Research Subjects ◽  
The People ◽  
The Government ◽  
The Relationship ◽  
Mutual Agreement

This study aims to determine the local wisdom of the people of Desa Adat Kuta, Badung Regency, Bali Province, in building harmony between Muslims and Hindus. This study uses social integration theory as a basis for seeing the assimilation and unification of Muslims and Hindus. This study used a qualitative method with the research subjects of village officials, Muslim and Hindu religious leaders, and community leaders. The results showed that the community's wisdom in the Desa Adat Kuta is a hereditary tradition, in the form of mutual agreement in regulating the relationship between Muslims and Hindus, based on the teachings and principles of their respective religions. The sense of kinship in the Desa Adat Kuta is woven through the Nyama Selam and Nyama Hindu traditions. The harmony of Muslims and Hindus is manifested in the freedom to practice worship, Muslims based on the teachings and principles of Ukhuwah Insaniyah and Hindus based on the teachings and principles of Tri Hita Karana. The existence of equality and tolerance does not lead to conflict, including in establishing places of worship because they are regulated by the government and there is intense communication in the Forum for Religious Harmony.

Problematic Internet Use digunakan Ketika Kesepian pada Remaja

2020 ◽  
Vol 14 (1) ◽  
pp. 45-60
Author(s):  
Yashinta Yashinta ◽  
Dwi Hurriyati
Keyword(s):  
Internet Use ◽  
Hypothesis Test ◽  
Problematic Internet Use ◽  
Coefficient Of Determination ◽  
Test Results ◽  
Research Subjects ◽  
Significance Level ◽  
Relationship Of ◽  
The Relationship ◽  
Effective Contribution

This study aims to determine the relationship of loneliness with problematic internet use on boarding students on Silaberanti street in Siantan jaya Opposite Ulu 1 Palembang city. Research subjects numbered 220 people using random sampling methods. Data was collected using a 60 item problematic internet use scale and a 60 item loneliness. Realibility is generated on scale of problematic internet use of 0,955 and loneliness of 0,946.Hypothesis testing uses product moment correlation analysis techniques. Hypothesis test results showed a positive relationshif between loneliness with problematic internet use on boarding students on Silaberanti street in Siantan jaya Opposite Ulu 1 Palembang city r= 0,684 with a significance level of 0,000 (p<0,01). Loneliness in this study made an effective contribution of 46,8% to problematic internet use which can be seen from the coefficient of determination (r²) that is equel to 0,468.

PERSOALAN KEHIDUPAN KONTEMPORER: MENGGAGAS KAJIAN SACHEDINA TENTANG THEOLOGI PLURALISME

EMPIRISMA ◽  
2017 ◽  
Vol 26 (1) ◽  
Author(s):  
Limas Dodi
Keyword(s):  
Religious Pluralism ◽  
Main Argument ◽  
Religious Groups ◽  
Common View ◽  
The Public ◽  
The People ◽  
Muslim Majority ◽  
The Common ◽  
The Relationship ◽  
Religious Differences

According to Abdulaziz Sachedina, the main argument of religious pluralism in the Qur’an based on the relationship between private belief (personal) and public projection of Islam in society. By regarding to private faith, the Qur’an being noninterventionist (for example, all forms of human authority should not be disturb the inner beliefs of individuals). While the public projection of faith, the Qur’an attitude based on the principle of coexistence. There is the willingness of the dominant race provide the freedom for people of other faiths with their own rules. Rules could shape how to run their affairs and to live side by side with the Muslims. Thus, based on the principle that the people of Indonesia are Muslim majority, it should be a mirror of a societie’s recognizion, respects and execution of religious pluralism. Abdul Aziz Sachedina called for Muslims to rediscover the moral concerns of public Islam in peace. The call for peace seemed to indicate that the existence of increasingly weakened in the religious sense of the Muslims and hence need to be reaffi rmed. Sachedina also like to emphasize that the position of peace in Islam is parallel with a variety of other doctrines, such as: prayer, fasting, pilgrimage and so on. Sachedina also tried to show the argument that the common view among religious groups is only one religion and traditions of other false and worthless. “Antipluralist” argument comes amid the reality of human religious differences. Keywords: Theology, Pluralism, Abdulaziz Sachedina

Administrasi Hubungan Sekolah dan Masyarakat (HUSEMAS)

2020 ◽  
Author(s):  
Rifa Nirmala ◽  
Hade Afriansyah
Keyword(s):  
Personal Growth ◽  
Clear Picture ◽  
Public And Private ◽  
Community Needs ◽  
The People ◽  
Good Will ◽  
Relationship Of ◽  
The Relationship

Thus can drawing conclusions about the relationship of the school with the community is essentially a very decisive tool in fostering and developing the personal growth of students in schools. If the relationship between the school and the community goes well, the sense of responsibility and participation of the community to advance the school will also be good and high. In order to create relationships and cooperation between schools and the community, the community needs to know and have a clear picture of the school they have obtained.The presence of schools is based on the good will of the country and the people who support it. Therefore people who work in schools inevitably have to work with the community. The community here can be in the form of parents of students, agencies, organizations, both public and private. One reason schools need help from the community where schools are because schools must be funded.

‘Nature Has Its Own Soul and Speaks Its Own Language’

2010 ◽  
Vol 19 (2) ◽  
pp. 62-73
Author(s):  
Helena Ruotsala
Keyword(s):  
National Park ◽  
Tourism Industry ◽  
Reindeer Herding ◽  
Nature Protection ◽  
Economic Interests ◽  
Finnish Lapland ◽  
The People ◽  
Heated Debate ◽  
The 1960S ◽  
The Relationship

Nature and environment are important for the people earning their living from natural sources of livelihood. This article concentrates on the local perspective of the landscape in the Pallastunturi Fells, which are situated in Pallas-Ylläs National Park in Finnish Lapland. The Fells are both important pastures for reindeer and an old tourism area. The Pallastunturi Tourist Hotel is situated inside the national park because the hotel was built before the park was established 1938. Until the 1960s, the relationship between tourism and reindeer herding had been harmonious because the tourism activities did not disturb the reindeer herding, but offered instead ways to earn money by transporting the tourists from the main road to the hotel, which had been previously without any road connections. During recent years, tourism has been developed as the main source of livelihood in Lapland and huge investments have been made in several parts of Lapland. One example of this type of investment is the plan to replace the old Pallas Tourist hotel, which was built in 1948, with a newer and bigger one. It means that the state will allow a private enterprise to build more infrastructures for tourism inside a national park where nature should be protected and this has sparked a heated debate. Those who oppose the project criticise this proposal as the amendment of a law designed to promote the economic interests of one private tourism enterprise. The project's supporters claim that the needs of the tourism industry and nature protection can both be promoted and that it is important to develop a tourist centre which is already situated within the national park. This article is an attempt to try to shed light on why the local people are so loudly resisting the plans by a private tourism enterprise to touch the national park. It is based on my fieldwork among reindeer herding families in the area.

Waldaufseher und Waldfrevler in Chur zwischen 1750 und 1840 Durch die Analyse von interaktiven Konfliktfeldern zum besseren Verständnis des vorindustriellen Waldes | Forest wardens and forest offenders in Chur between 1750 and 1840. This analysis of interactive fields of conflict seeks to arrive at a better understanding of pre-industrial forests

2006 ◽  
Vol 157 (9) ◽  
pp. 408-412
Author(s):  
Jörg Spinatsch
Keyword(s):  
Cohesive Elements ◽  
Court Records ◽  
The People ◽  
The Relationship

This study is an attempt to unravel the complexity of preindustrial illicit forest abuse. By means of a survey on forest crime, together with associated existing fields of conflict,the importance of the forest for the people of the time, with particular emphasis on the illicit aspect, are illustrated. As an example, we have looked at the relationship between the forest wardens and forest offenders in Chur between 1750 and 1840. The focus of the analysis is on the ambivalence of this relationship, conditioned as it is by both conflictual and cohesive elements. Exerts taken from court records of the time illustrate the proximity of disagreements and collaboration.

SELF-HARM IN ADOLESCENCE

2020 ◽  
Author(s):  
Remus Runcan ◽  
Patricia Luciana Runcan ◽  
Cosmin Goian ◽  
Bogdan Nadolu ◽  
Mihaela Gavrilă Ardelean
Keyword(s):  
Substance Misuse ◽  
Deliberate Self Harm ◽  
The People ◽  
Self Harm ◽  
Relationship Of ◽  
The Relationship

This study provides the synonyms for the terms deliberate self-harm and self-destructive behaviour, together with a psychological portrait of self-harming adolescents, the consequence of self-harm, the purpose of self-harm, and the forms of self-harm. It also presents the results of a survey regarding the prevalence of people with non-suicidal self-harming behaviour, the gender of people with non-suicidal self-harming behaviour, the age of the first non-suicidal self-harming behaviour in these people, the frequency of non-suicidal self-harming behaviour in these people, the association of the non-suicidal self-harming behaviour with substance misuse in these people, the relationships of the people with non-suicidal self-harming behaviour with their fathers, mothers, and siblings, the relationships of the people with non-suicidal self-harming behaviour with their friends, the possible causes of self-harming behaviour in these people, and the relationship of people with non-suicidal self-harming behaviour with religion. Some of the results confirmed literature results, while others shed a new light on other aspects related to people with non-suicidal self-harming behaviour

Abilities of Physics Education Students in Constructing Graphics Based on Practicum Results and in Interpreting It

2020 ◽  
Vol 3 (1) ◽  
pp. 35-44
Author(s):  
Hariawan Hariawan ◽  
Muslimin Muslimin ◽  
I Komang Werdhiana
Keyword(s):  
Physics Education ◽  
Research Subjects ◽  
Education Students ◽  
Study Program ◽  
Thinking Aloud ◽  
Training And Education ◽  
Education Study ◽  
Basic Physics ◽  
Undergraduate Physics Education ◽  
The Relationship

The skills to construct and interpret graphs are a form of science skills and are an important component in learning physics. The purpose of this study was to describe the ability of undergraduate physics education students to construct graphs based on practicum data and interpret them. Data obtained through respondent answer sheets, thinking-aloud recordings, and interviews. The research was conducted at the Faculty of Teacher Training and Education (FKIP) Untad and the research subjects of the Physics Education Study Program students were 6 people obtained based on the values of Basic Physics I and Basic Physics practicum II then divided into three groups of levels (high, medium, and low) with each category as many as 2 people. The results of this study indicate: 1) in general, respondents in the high, medium, and low categories can construct graphs but are not based on the prerequisite ability to construct graphs, especially in determining the x-axis and y-axis variables, 2) on the ability to interpret graphs, respondents can interpret graphs the relationship between variables on the graph but not supported by an explanation or evaluation based on proper physics concepts, 3) The strategy used by respondents in constructing graphs, in general, is to convert data in decimal form or scientific notation and 4) The difficulties experienced by respondents when constructing graphs are converting data, determining the scale and how to determine the variables on each graph axis.    

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