scholarly journals Coffee consumption is associated with a reduced risk of venous thrombosis that is mediated through hemostatic factor levels

2012 ◽  
Vol 10 (12) ◽  
pp. 2519-2525 ◽  
Author(s):  
R. E. J. ROACH ◽  
B. SIEGERINK ◽  
S. le CESSIE ◽  
F. R. ROSENDAAL ◽  
S. C. CANNEGIETER ◽  
...  
Keyword(s):  
Venous Thrombosis ◽  
Coffee Consumption ◽  
Hemostatic Factor ◽  
Reduced Risk

scholarly journals Coffee consumption and risk of renal cell carcinoma in the NIH-AARP Diet and Health Study

2021 ◽  
Author(s):  
Jongeun Rhee ◽  
Erikka Loftfield ◽  
Neal D Freedman ◽  
Linda M Liao ◽  
Rashmi Sinha ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Cox Regression ◽  
Coffee Consumption ◽  
Health Study ◽  
Coffee Intake ◽  
Decaffeinated Coffee ◽  
Incident Cases ◽  
Reduced Risk

Abstract Background Coffee consumption has been associated with a reduced risk of some cancers, but the evidence for renal cell carcinoma (RCC) is inconclusive. We investigated the relationship between coffee and RCC within a large cohort. Methods Coffee intake was assessed at baseline in the National Institutes of Health–American Association of Retired Persons Diet and Health Study. Among 420 118 participants eligible for analysis, 2674 incident cases were identified. We fitted Cox-regression models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for coffee consumption vs non-drinkers. Results We observed HRs of 0.94 (95% CI 0.81, 1.09), 0.94 (0.81, 1.09), 0.80 (0.70, 0.92) and 0.77 (0.66, 0.90) for usual coffee intake of <1, 1, 2–3 and ≥4 cups/day, respectively (Ptrend = 0.00003). This relationship was observed among never-smokers (≥4 cups/day: HR 0.62, 95% CI 0.46, 0.83; Ptrend = 0.000003) but not ever-smokers (HR 0.85, 95% CI 0.70, 1.05; Ptrend = 0.35; Pinteraction = 0.0009) and remained in analyses restricted to cases diagnosed >10 years after baseline (HR 0.65, 95% CI 0.51, 0.82; Ptrend = 0.0005). Associations were similar between subgroups who drank predominately caffeinated or decaffeinated coffee (Pinteraction = 0.74). Conclusion In this investigation of coffee and RCC, to our knowledge the largest to date, we observed a 20% reduced risk for intake of ≥2 cups/day vs not drinking. Our findings add RCC to the growing list of cancers for which coffee consumption may be protective.

scholarly journals The Impact of Green Tea and Coffee Consumption on the Reduced Risk of Stroke Incidence in Japanese Population

Stroke ◽  
2013 ◽  
Vol 44 (5) ◽  
pp. 1369-1374 ◽  
Author(s):  
Yoshihiro Kokubo ◽  
Hiroyasu Iso ◽  
Isao Saito ◽  
Kazumasa Yamagishi ◽  
Hiroshi Yatsuya ◽  
...  
Keyword(s):  
Green Tea ◽  
Japanese Population ◽  
Coffee Consumption ◽  
Stroke Incidence ◽  
The Impact ◽  
Reduced Risk

Alcohol consumption is associated with a decreased risk of venous thrombosis

2008 ◽  
Vol 99 (01) ◽  
pp. 59-63 ◽  
Author(s):  
Frits R Rosendaal ◽  
Carine J. M Doggen ◽  
Elisabeth R Pomp
Keyword(s):  
Alcohol Consumption ◽  
Venous Thrombosis ◽  
Protective Factor ◽  
Large Population ◽  
Coagulation Factors ◽  
Population Based ◽  
Anticoagulation Clinics ◽  
Maximum Decrease ◽  
Control Study ◽  
Reduced Risk

SummaryModerate alcohol consumption is associated with lower levels of several coagulation factors. It is an established protective factor for cardiovascular disease; however, the effect on venous thrombosis is unknown. In a large population-based case-control study, we evaluated the association between alcohol consumption and the risk of venous thrombosis. The MEGA study included consecutive patients with a first venous thrombosis between March 1999 and September 2004 from six anticoagulation clinics in the Netherlands. Partners of patients were asked to participate, and additional controls were recruited using a random digit dialling method. All participants completed a standardized questionnaire, and blood samples were collected. A total of 4,423 patients and 5,235 controls were included in the analyses. Alcohol consumption was associated with a reduced risk of venous thrombosis, with 2–4 glasses per day resulting in the largest beneficial effect (odds ratio [OR] 0.67, 95% confidence interval [CI95] 0.58–0.77) compared to abstainers. The effect was more pronounced in women (OR 0.66, CI95 0.53–0.84) than men (OR 0.82, CI95 0.63–1.07) and also more striking for pulmonary embolism (OR 0.56, CI95 0.46–0.70) than for deep venous thrombosis of the leg (OR 0.74, CI95 0.63–0.88). Compared to abstainers, fibrinogen levels were decreased in individuals who consumed alcohol (maximum decrease: 0.30 g/l). FactorVII and vonWillebrand levels were mildly decreased in these individuals but not consistently over the categories of alcohol consumption. In conclusion, alcohol consumption is associated with a reduced risk of venous thrombosis, which may be in part mediated by decreased fibrinogen levels. Thromb

Coffee consumption associated with reduced risk of oral cancer: a meta-analysis

2016 ◽  
Vol 121 (4) ◽  
pp. 381-389.e1 ◽  
Author(s):  
Ya-Min Li ◽  
Juan Peng ◽  
Le-Zhi Li
Keyword(s):  
Oral Cancer ◽  
Meta Analysis ◽  
Coffee Consumption ◽  
Reduced Risk

scholarly journals Coffee consumption and reduced risk of hepatocellular carcinoma: findings from the Singapore Chinese Health Study

2011 ◽  
Vol 22 (3) ◽  
pp. 503-510 ◽  
Author(s):  
Shane Johnson ◽  
Woon-Puay Koh ◽  
Renwei Wang ◽  
Sugantha Govindarajan ◽  
Mimi C. Yu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Coffee Consumption ◽  
Health Study ◽  
Singapore Chinese ◽  
Reduced Risk

scholarly journals Coffee consumption and reduced risk of developing type 2 diabetes: a systematic review with meta-analysis

2018 ◽  
Vol 76 (6) ◽  
pp. 395-417 ◽  
Author(s):  
Mattias Carlström ◽  
Susanna C Larsson
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Meta Analysis ◽  
Coffee Consumption ◽  
Reduced Risk

Long-term coffee consumption associated with reduced risk of total and cause-specific mortality

2012 ◽  
Vol 18 (3) ◽  
pp. 116-117 ◽  
Author(s):  
Esther Lopez-Garcia
Keyword(s):  
Coffee Consumption ◽  
Specific Mortality ◽  
Reduced Risk

Diet in alcohol withdrawal - coffee consumption is associated with reduced risk of alcohol-induced liver fibrosis and steatosis

2021 ◽  
Author(s):  
L Gatterer ◽  
C Grander ◽  
M Riederer ◽  
W Grander ◽  
J Marksteiner ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Alcohol Withdrawal ◽  
Coffee Consumption ◽  
Reduced Risk
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