Tongue atrophy as a neurological finding in hereditary polyneuropathy in Alaskan malamutes

Objective: During the late 2019, a group of patients had unexplained chest infections in Wuhan which turned out to be the new pandemic coronavirus disease 2019 (COVID-19). New neurological symptoms have been reported in COVID-19 patients. Posterior reversible encephalopathy syndrome (PRES) is a new neurological finding and is associated or caused by COVID-19. Case Presentation: A 32-year-old lady, with no medical background had COVID-19 infection and needed mechanical ventilation. After surviving the intensive care, she started to have multiple seizures that required general anesthesia to be aborted. The patient turned out to have PRES. Conclusion: PRES is a neurological syndrome causing seizures, headaches, and blurred vision. It is usually associated with high blood pressure, renal failure, and other risk factors. The patient in this case had nearly normal blood pressure, but still had a diagnosis of PRES. The new reported neurological symptoms associated with COVID-19 infection need further research and attention from the academic society to predict and prevent the morbidity and mortality of COVID-19 patients.

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Isolated convergence-retraction nystagmus secondary to intralesional haemorrhage of a pineal cyst: an easily missed neurological finding with potentially life-threatening consequences

BMJ Case Reports ◽

10.1136/bcr-2019-233469 ◽

2020 ◽

Vol 13 (9) ◽

pp. e233469

Author(s):

Kristine Woodward ◽

Amith Sitaram ◽

Steven Peters

Keyword(s):

Case Report ◽

Stable Condition ◽

Visual Disturbance ◽

Clinical Findings ◽

Close Monitoring ◽

Pineal Cyst ◽

Haemorrhagic Transformation ◽

Neurological Finding ◽

Life Threatening ◽

Secondary Haemorrhage

This case report describes a patient who presented to the emergency department with intermittent visual disturbance and was found to have convergence-retraction nystagmus. This occurred in the setting of supratherapeutic anticoagulation on warfarin for an aortic dissection graft repair. Urgent imaging demonstrated haemorrhagic transformation of a previously identified incidental pineal cyst. After close monitoring given the risk of secondary hydrocephalus, the patient was discharged in stable condition with symptom resolution and without any further significant complications. This case report highlights the importance of identifying subtle clinical findings and the risk of secondary haemorrhage of pineal cysts when on anticoagulation. While the risk of secondary hydrocephalus is a significant concern, clinically stable patients can be followed without need for neurosurgical intervention.

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Man-in-the-barrel syndrome after thoracoilium fusion

Journal of Neurosurgery Spine ◽

10.3171/spi.2008.8.08485 ◽

2008 ◽

Vol 9 (6) ◽

pp. 566-569 ◽

Cited By ~ 1

Author(s):

Andrei F. Joaquim ◽

Catherine C. Shaffrey ◽

Charles A. Sansur ◽

Christopher I. Shaffrey

Keyword(s):

Back Pain ◽

Cerebral Ischemia ◽

Early Postoperative Period ◽

Sagittal Imbalance ◽

Lumbar Stenosis ◽

Degenerative Scoliosis ◽

Neurological Finding ◽

Brachial Diplegia ◽

Junctional Kyphosis ◽

Difficulty Walking

The authors report a case of man-in-the-barrel (MIB) syndrome occurring after an extensive revision involving thoracoilium instrumentation and fusion for iatrogenic and degenerative scoliosis, progressive kyphosis, and sagittal imbalance. Isolated brachial diplegia is a rare neurological finding often attributed to cerebral ischemia. It has not been previously reported in patients undergoing complex spine surgery. This 70-year-old woman, who had previously undergone T11–S1 fusion for lumbar stenosis and scoliosis, presented with increased difficulty walking and with back pain. She had junctional kyphosis and L5–S1 pseudarthrosis and required revision fusion extending from T-3 to the ilium. In the early postoperative period, she experienced a 30-minute episode of substantial hypotension. She developed delirium and isolated brachial diplegia, consistent with MIB syndrome. Multiple studies were performed to assess the origin of this brachial diplegia. There was no definitive radiological evidence of any causative lesion. After a few days, her cognitive function returned to normal and she regained the ability to move her arms. After several weeks of rehabilitation, she recovered completely. Man-in-the-barrel syndrome is a rare neurological entity. It can result from various mechanisms but most commonly seems to be related to ischemia and is potentially reversible.

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Oto-Neurological Finding in Post-Traumatic Encephalopathy

Acta Oto-Laryngologica ◽

10.3109/00016486309127449 ◽

1963 ◽

Vol 56 (2-6) ◽

pp. 546-554 ◽

Cited By ~ 2

Author(s):

Jaakko S. Lumio ◽

Juhani Aho

Keyword(s):

Neurological Finding ◽

Post Traumatic

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Temporal changes in the documentation of neurological findings among patients with acute ischaemic stroke in a single centre in Japan: a retrospective cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2017-019480 ◽

2017 ◽

Vol 7 (12) ◽

pp. e019480

Author(s):

Junpei Komagamine ◽

Tomoko Komagamine

Keyword(s):

Ischaemic Stroke ◽

Acute Ischaemic Stroke ◽

Cranial Nerves ◽

Stroke Care ◽

Temporal Changes ◽

Sensory Function ◽

Cross Sectional ◽

The Third ◽

Neurological Findings ◽

Neurological Finding

ObjectiveTo evaluate temporal differences in the documentation of neurological findings by the same physicians in patients with ischaemic stroke while in hospital. We also investigated differences in the rate of documentation of neurological findings in patients with stroke between internists and neurosurgeons.DesignA retrospective medical chart review.ParticipantsHospitalised adult patients with acute ischaemic stroke who stayed 7 or more days in our hospital. Neurosurgeons (n=8) and internists (n=19) caring for these patients (including up to 10 patients per physician).Main outcome measuresThe documentation rate of any neurological finding in the patients on each day (from day 1 to 7 and on discharge). The documentation rates of eight neurological finding components (consciousness, mental status, cranial nerves, motor function, sensory function, coordination, reflexes and gait). We included only documentation by the same physician. Fisher’s exact test was used to evaluate differences in outcomes between neurosurgeons and internists.ResultsDuring the study period, we identified 172 patients with stroke who were cared for by 27 physicians. The documentation rates of any neurological findings were 94% (day 1), 58% (day 2), 35% (day 3), 40% (day 4), 32% (day 5), 30% (day 6) and 23% (day 7). On discharge, all eight neurological finding components were documented in less than 10% of all cases. The documentation rate was significantly higher by internists than that by neurosurgeons on each day but not on discharge.ConclusionsThe documentation rate of neurological findings by physicians during usual stroke care decreased to less than 50% after the third hospital day. Given the importance of temporal changes in the neurological symptoms of patients with stroke, further study is needed to determine whether this low documentation rate after the third hospital day was due to a lack of physician interest in neurological findings or other factors.

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The frequency-amplitude gradient in the sleep EEG of children and its diagnostic significance

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2007000200004 ◽

2007 ◽

Vol 65 (2A) ◽

pp. 206-211 ◽

Cited By ~ 2

Author(s):

Carlos Nogueira Aucélio ◽

Ernst Niedermeyer ◽

Áurea Nogueira de Melo

Keyword(s):

Neurological Disorder ◽

Sleep Stage ◽

Strong Association ◽

Age Group ◽

Chi Square ◽

Diagnostic Significance ◽

Neurological Findings ◽

Neurological Finding ◽

Age Dependent ◽

Chi Square Test

OBJECTIVE: 1014 EEGs of children in the 3-months to 12-years age group were obtained during sleep with the purpose of assessing the frequency and amplitude gradient (FAG) its absence thought to be an indicator of neurological disorder. METHOD: FAG findings were divided into present/absent. The neurological findings were classified according to the presence (abnormal neurological finding-ANF) or absence (normal neurological finding-NNF) of neurological disorder. The association and significance between FAG and neurological findings was determined by prevalence ration (PR) and chi-square test (chi2). RESULTS: FAG showed a characteristic distributions of voltage output during non-REM sleep, stage II, in the 3-months to 5-years age group with NNF. The PR and the chi2 test demonstrated a strong association between FAG absent and ANF. CONCLUSION: FAG is an age-dependent EEG sleep parameter and absence of FAG in the 3-months to 5-years age group is highly suggestive of neurological disorder.

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HIV-related neurological finding in drug users

Biological Psychiatry ◽

10.1016/0006-3223(89)91673-9 ◽

1989 ◽

Vol 25 (7) ◽

pp. A92

Author(s):

J. Weiner ◽

L. Handelsman ◽

A.J. Rowan ◽

M. Aronson ◽

T. Horvath

Keyword(s):

Drug Users ◽

Neurological Finding

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THE NEUROLOGICAL FACE OF CELIAC DISEASE

Arquivos de Gastroenterologia ◽

10.1590/s0004-28032015000300002 ◽

2015 ◽

Vol 52 (3) ◽

pp. 167-170 ◽

Cited By ~ 11

Author(s):

Sedat IŞIKAY ◽

Halil KOCAMAZ

Keyword(s):

Celiac Disease ◽

Medical Records ◽

Laboratory Data ◽

Cross Sectional Study ◽

Breath Holding ◽

Neurological Manifestations ◽

Cross Sectional ◽

Hyperactivity Disorder ◽

Neurological Finding ◽

Significant Difference

BackgroundSeveral neurological disorders have also been widely described in celiac disease patients.ObjectiveThe aim of this study was to determine the incidence of accompanying different neurologic manifestations in children with celiac disease at the time of diagnosis and to discuss these manifestations in the light of the recent literature.MethodsThis prospective cross sectional study included 297 children diagnosed with celiac disease. The medical records of all patients were reviewed.ResultsIn neurological evaluation, totally 40 (13. 5%) of the 297 celiac patients had a neurological finding including headache, epilepsy, migraine, mental retardation, breath holding spells, ataxia, cerebral palsy, attention deficit hyperactivity disorder, Down syndrome and Turner syndrome in order of frequency. There was not any significant difference between the laboratory data of the patients with and without neurological manifestations. However; type 3a biopsy was statistically significantly more common among patients without neurological manifestations, while type 3b biopsy was statistically significantly more common among patients with neurological manifestations.ConclusionIt is important to keep in mind that in clinical course of celiac disease different neurological manifestations may be reported.

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Hypoxic-ischemic encefalopathy: Clinical course and prognosis

Vojnosanitetski pregled ◽

10.2298/vsp0303291c ◽

2003 ◽

Vol 60 (3) ◽

pp. 291-297

Author(s):

Natasa Cosic-Cerovac ◽

Slobodanka Todorovic ◽

Nebojsa Jovic ◽

Milica Prostran

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Neurological Disorders ◽

Clinical Course ◽

Newborn Infants ◽

Neurological Development ◽

Resonance Imaging ◽

Neurological Finding ◽

The Brain ◽

Ischemic Encephalopathy

Background. Establishing the value of neurological examination, and additional diagnostic methods (ultrasonography and magnetic resonance imaging of the brain) in the diagnosis and prognosis of hypoxic-ischemic encephalopathy and its treatment, tracking the clinical course, and making the prognosis of neurological development in newborn infants with hypoxic-ischemic encefalopathy. Methods. The group of 40 term newborn infants with suspected intrauterine asphyxia was examined. All the infants were prospectivelly followed untill the 3rd year of age at the Clinic for Neurology and Psychiatry for Children and Youth in order to estimate their neurological development and to diagnose the occurence of persistent neurological disorders. All the infants were analyzed by their gestational age and Apgar score in the 1st and the 5th minute of life. They were all examined neurologically and by ultrasonography in the first week of life and, repeatedly, at the age of 1, 3, 6, 9, 12, 18, as well as in the 24th month of life. They were treated by the standard methods for this disease. Finally, all the infants were examined neurologically and by magnetic resonance imaging of the brain in their 3rd year of age. On the basis of neurological finding infants were devided into 3 groups: infants with normal neurological finding, infants with mild neurological symptomatology, and infants with severe neurological disorders. Results. It was shown that neurological finding, ultrasonography and magnetic resonance imaging of the brain positively correlated with the later neurological development of the infants with hypoxic-ischemic encephalopathy. Conclusion. Only the combined use of these techniques had full diagnostic and prognostic significance emphasizing that the integrative approach was very important in the diagnosis of brain lesions in infants.

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Correlation between neurological finding and gestational maturity of newborns determined by neurosonography

Medicinski pregled ◽

10.2298/mpns0806281i ◽

2008 ◽

Vol 61 (5-6) ◽

pp. 281-285 ◽

Cited By ~ 1

Author(s):

Nevenka Ilic ◽

Slobodan Obradovic ◽

Jasmina Djindjic ◽

Gordana Kostic ◽

Olivera Laban ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Neurological Status ◽

Functional Condition ◽

Hypoxic Ischemic Encephalopathy ◽

Premature Babies ◽

Neurological Finding ◽

Vital Functions ◽

Gestation Age ◽

Ischemic Encephalopathy

Introduction Maturity is a complex functional condition influenced especially by the development of the vital functions of a fetus, primarily by the degree of the development of its central nervous system. The aim of this investigation was to establish the gestational maturity of the nervous system by neurosonography and neurological status. Material and methods The parameter of the neurological maturity, compared in this research are a neurological status and the degree of girification established by the ultrasound. Results All the coefficients of correlation between the gestation age determined by the ultrasound and the establishing of the gestation based on the neurological findings show a statistically significant correlation for p<0.01. Of particular parametres of the neurological evaluation , the most appropriate ones appeared to be reflexes (the reflex of crossed extension, Moro reflex and the reflex of the main points), then volar flexion of a hand and the poplietal corner as the indicator of the passive tonus, whereas within the area of the evaluation of the active tonus, the motility was the most valid for establishing the maturity of a neonatal. The lowest coefficients of the correlations were in the automatic walk and the active tonus of the neck flexor, which are the ones of the most common neurological indicators of hypoxic ischemic encephalopathy of a neonatal. Conclusions Bearing in mind that the premature babies are a risky group for existence of perinatal brain damages, we believe the neurosonographic establishing of the gestation age to be a precise and comfortable indicator of the maturity of the nervous system.

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