scholarly journals Spotlight on… multiple pregnancy

2021 ◽  
Vol 23 (4) ◽  
pp. 236-236
Author(s):  
George Attilakos
Keyword(s):  
Multiple Pregnancy

Multiple pregnancy after IVF: A retrospective study

1995 ◽  
Author(s):  
R. Berkhout ◽  
F. J. Snoek ◽  
R. Schats
Keyword(s):  
Retrospective Study ◽  
Multiple Pregnancy

Repeat abortion: Personal, interpersonal, and situational correlates of multiple pregnancy termination

2004 ◽  
Author(s):  
Paul Shuper ◽  
William Fisher ◽  
Sony Singh ◽  
Jennifer Gunter ◽  
Mark Carey
Keyword(s):  
Pregnancy Termination ◽  
Multiple Pregnancy

The role of inflammatory cytokines in the pathogenesis of premature labor in multiple pregnancy as a result of ART

2016 ◽  
pp. 73-76
Author(s):  
B.M. Ventskivskiy ◽  
◽  
I.V. Poladych ◽  
S.O. Avramenko ◽  
◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Inflammatory Cytokines ◽  
Proinflammatory Cytokines ◽  
Local Level ◽  
Multiple Pregnancy ◽  
Reproductive Technology ◽  
System Level ◽  
Premature Labor ◽  
Pro Inflammatory Cytokines

In recent years there has been an increase in the frequency of multiple pregnancies and the associated perinatal losses. It is a result of multiple pregnancy in ART refers to a high-risk gestation, at which premature births occur in 2 times more often than in singleton pregnancies. The objective: to determine the role of pro-inflammatory cytokines in the pathogenesis of premature labor in multiple pregnancy, as a result of assisted reproductive technology. Patients and methods. to determine the pro-inflammatory cytokines that all pregnant with bagtopliddyam held immunosorbent assay, defined concentrations of interleukin (IL) in serum and cervical mucus. Results. The analysis of the levels of pro-inflammatory cytokines (IL-1, IL-8) in the test environment, found high concentrations in the surveyed women with multiple pregnancy, due to the use of ART, compared with spontaneous multiple and singleton pregnancy. Increased concentration of proinflammatory cytokines in patients with multiple pregnancy by ART is associated with their synthesis at the system level, it stimulated foci of inflammation in the female genitals and extragenital localization. This correlates with the clinical data and statistical analysis, patients with multiple pregnancy as a result of ART had weighed infectious-inflammatory history. Conclusion. The study showed that elevated levels of proinflammatory cytokines in the systemic and local level in patients with multiple pregnancy due to ART, typical for women with miscarriage, because of the physiological course of pregnancy characterized by the predominance of anti-inflammatory cytokines that prevent rejection of the fetus as a foreign factor. Based on the data obtained proved the role of systemic inflammatory factors in the genesis of preterm labor in women with a multiple pregnancy, as a result of assisted reproductive technology. Key words: multiple pregnancy, assisted reproductive technology, premature birth, interleukine-1, interleukine-8.

Delayed interval delivery of the second and third fetuses in multiple pregnancy triplet (Сase report)

2016 ◽  
pp. 148-152
Author(s):  
Y. Dubossarskaya ◽  
◽  
L. Padalko ◽  
L. Zakharchenko ◽  
E. Savel’eva ◽  
...  
Keyword(s):  
Preterm Delivery ◽  
Multiple Pregnancy ◽  
Bed Rest ◽  
Perinatal Morbidity ◽  
Perinatal Complications ◽  
Triplet Pregnancy ◽  
Satisfactory Condition ◽  
Nulliparous Women ◽  
Perinatal Center ◽  
Delayed Interval Delivery

This article describes a clinical case of vaginal delivery in nulliparous women 24 years old delayed interval delivery of the second and third fetuses in spontaneous multiple pregnancy dichorionic triamniotic triplet in a tertiary perinatal center. After preterm delivery in 27+5 weeks of gestation the first fetus to reduce perinatal morbidity and mortality of two fetuses that are left in the uterus, with informed consent of the woman preterm delivery the second and third fetuses occurred at intervals of 38 days, in 33+1 weeks of gestation. Careful monitoring of the state of the mother and fetuses was conducted. To increase the interval between the birth of the first fetus and the second and the third fetuses, prevention of obstetric and perinatal complications used tocolysis, antibiotics, progesterone, the prevention of respiratory distress syndrome of the newborn by corticosteroids and bed rest. Three girls were born alive with a weight of 980, 1800 and 1950 grams correspondingly. Childbirth complicated second degree perineal laceration and retained portions of placenta and membranes, puerperal period was uneventful. After 1.5 months, all infants discharged with her mother in a satisfactory condition with a weight of more than 3000 grams. Key words: multiple pregnancy, triplet pregnancy, delayed interval delivery in triplet pregnancy, preterm delivery.

REPRODUCTIVE QUALITIES OF PIGS AT CROSSING

2020 ◽  
Keyword(s):  
Milk Production ◽  
Multiple Pregnancy ◽  
Average Weight ◽  
High Fertility ◽  
Agricultural Producers ◽  
Pig Farm ◽  
Safe Food

Providing the population with quality and safe food, in particular meat, is one of the main tasks facing agricultural producers. An important role is assigned to pig breeding, since pigs are characterized by high fertility and precocity [1, p. 25]. The aim of the work was to assess the productive qualities ofpure-bred and hybrid sows when crossing with purebred boars. The studies were conducted in the pig farm "Slavyanka". Productive qualities of sows were assessed by multiple pregnancy, large young, milk production, weight of the nest at birth and on the 30th day at weaning, as well as by the level ofpigs’ safety. These studies showed that hybrid sows outperformed purebred sows (13.70±0.40) in multiple pregnancy (14.6±0.04 piglets). The milk content of purebred sows was lower by 4.73 kg or 10.50 % than that of two-breed hybrids. The mass ofpiglets’ nest at birth in crossbred sows when crossing with Pietrain boar outperformed the mass ofpurebred sows’ nests by 3.4 kg, or 17,60%. The output of business piglets was almost the same and amounted to 13.01 heads have hybrid sows and 12.05 heads purebred. Safety of piglets was, respectively, 90% and 87%. Two-breed hybrids significantly outperformed purebred sows by nest weight at weaning by 14.3%, the average weight of one pig by 9.42%. Thus, studies have shown that crossbred sows crossed by terminal boar of Pietren breed, outperformed purebred ones on many para-metres.

scholarly journals Physical Activity Patterns of Women with a Twin Pregnancy—A Cross-Sectional Study

2021 ◽  
Vol 18 (15) ◽  
pp. 7724
Author(s):  
Katarzyna Kwiatkowska ◽  
Katarzyna Kosińska-Kaczyńska ◽  
Izabela Walasik ◽  
Agnieszka Osińska ◽  
Iwona Szymusik
Keyword(s):  
Physical Activity ◽  
Pregnant Women ◽  
Twin Pregnancy ◽  
Activity Patterns ◽  
Multiple Pregnancy ◽  
Cross Sectional Study ◽  
Sources Of Information ◽  
Sectional Study ◽  
Cross Sectional ◽  
Physically Active

Background: No specific physical activity guidelines are available for women in multiple pregnancy. Aim of the study was to assess the knowledge and experience of women regarding physical activity during their latest twin pregnancy. Methods: A cross-sectional study including women after a twin delivery was conducted in Poland. A questionnaire was distributed in 2018 via web pages and Facebook groups designed for pregnant women. Results: 652 women filled out the questionnaire completely. Only 25% of women performed any physical exercises during twin gestation. The frequency of preterm delivery was similar in physically active and non-active participants. 35% of the respondents claimed to have gained information on proper activity from obstetricians during antenatal counselling while 11% claimed to be unable to identify the reliable sources of information. 7% of women admitted to feel discriminated by social opinion on exercising during a twin pregnancy. Conclusions: The population of women with a twin gestation is not sufficiently physically active and is often discouraged from performing exercises during gestation. Therefore, it is crucial to inform obstetricians to recommend active lifestyle during a twin gestation and to provide reliable information on physical activity to pregnant women. Further research on this topic is necessary in order for obstetric providers to counsel women on appropriate exercise with a twin pregnancy.

scholarly journals Controlled ovarian stimulation should not be preferred for male infertility treated with intrauterine insemination: a retrospective study

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Yan Tang ◽  
Qian-Dong He ◽  
Ting-Ting Zhang ◽  
Jing-Jing Wang ◽  
Si-Chong Huang ◽  
...  
Keyword(s):  
Ectopic Pregnancy ◽  
Pregnancy Rate ◽  
Ovarian Stimulation ◽  
Intrauterine Insemination ◽  
Multiple Pregnancy ◽  
Clinical Pregnancy ◽  
Male Factor Infertility ◽  
Male Factor ◽  
Ovulatory Follicles ◽  
Multiple Pregnancy Rate

Abstract Background Some studies have stated that intrauterine insemination (IUI) with controlled ovarian stimulation (COS) might increase the pregnancy rate, while others suggest that IUI in the natural cycle (NC) should be the first line of treatment. It remains unclear whether it is necessary to use COS at the same time when IUI is applied to treat isolated male factor infertility. Thus, we aimed to investigate efficacy of IUI with COS for isolated male factor infertility. Methods A total of 601 IUI cycles from 307 couples who sought medical care for isolated male factor infertility between January 2010 and February 2020 were divided into two groups: NC-IUI and COS-IUI. The COS-IUI group was further divided into two subgroups according to the number of pre-ovulatory follicles on the day of HCG: cycles with monofollicular development (one follicle group) and cycles with at least two pre-ovulatory follicles (≥ 2 follicles group). The IUI outcomes, including clinical pregnancy, live birth, spontaneous abortion, ectopic pregnancy, and multiple pregnancy rates were compared. Results The clinical pregnancy, live birth, spontaneous abortion, and ectopic pregnancy rates were comparable between the NC-IUI and COS-IUI group. Similar results were also observed among the NC-IUI, one follicle, and ≥ 2 follicles groups. However, with respect to the multiple pregnancy rate, a trend toward higher multiple pregnancy rate was observed in the COS-IUI group compared to the NC-IUI group (8.7% vs. 0, P = 0.091), and a significant difference was found between the NC-IUI and ≥ 2 follicles group (0 vs. 16.7%, P = 0.033). Conclusion In COS cycles, especially in those with at least two pre-ovulatory follicles, the multiple pregnancy rate increased without a substantial gain in overall pregnancy rate; thus, COS should not be preferred in IUI for isolated male factor infertility. If COS is required, one stimulated follicle and one healthy baby should be the goal considering the safety of both mothers and foetuses.

N-acetyl-cysteine as adjuvant therapy in female infertility: a systematic review and meta-analysis

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Nagita Devi ◽  
Chandrasekhar Boya ◽  
Manik Chhabra ◽  
Dipika Bansal
Keyword(s):  
Adjuvant Therapy ◽  
Randomized Controlled Trials ◽  
Pregnancy Rate ◽  
Multiple Pregnancy ◽  
Female Infertility ◽  
Cochrane Library ◽  
Controlled Trials ◽  
Miscarriage Rate ◽  
Randomized Controlled ◽  
Acetyl Cysteine

AbstractObjectivesThe objective of this study is to explore the efficacy and safety of N-acetyl-cysteine (NAC) as adjuvant therapy in female infertility.ContentWe performed a systematic literature search of PubMed, Cochrane Library, Embase, and Ovid databases through April 2019 for Randomized Controlled Trials (RCTs) evaluating the effectiveness and safety of NAC as adjuvant therapy in female infertility. The outcomes assessed were rates of ovulation, pregnancy, miscarriage and multiple pregnancy, presented as pooled odds ratio with 95% confidence interval (CI) using the random-effects model. Heterogeneity and inconsistency of the measurements were identified through Cochrane’s Q statistic and I2 statistic. We also performed a sensitivity analysis, publication bias (using funnel plot and Begg’s test), and subgroup analysis.SummaryFifteen RCTs recruiting 2330 female receiving NAC were included. The pooled estimate showed the statistically insignificant improvement in outcomes; clinical pregnancy rate 1.55 (95% CI 0.98–2.47; I2=68%; p<0.01), ovulation rate 1.77 (95% CI 0.76–4.14; I2=90%; p<0.01), multiple pregnancy rate 0.83 (95% CI 0.34–1.99; I2=10%; p=0.31) and miscarriage rate 0.76 (95% CI= 0.37, 1.53; I2=0%; p=0.69) . NAC was found less efficacious and safe than metformin in all outcomes. Overall, NAC showed statistically insignificant (OR=0.98–2.47).OutlookNAC can be an effective adjuvant in PCOS related and unexplained female infertility. The effect could be more profound in women with high BMI, insulin resistance, and oxidative stress. However, the findings need further confirmation in well-designed randomized controlled trials to examine clinical outcomes such as live birth rate in more extended follow-up periods.

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