On the Natural Lubrication of Synovial Joints: Normal and Degenerate

1977 ◽  
Vol 99 (2) ◽  
pp. 163-172 ◽  
Author(s):  
Joseph M. Mansour ◽  
Van C. Mow

Fluid flow and mass transport mechanisms associated with articular cartilage function are important biomechanical processes of normal and pathological synovial joints. A three-layer permeable, two-phase medium of an incompressible fluid and a linear elastic solid are used to model the flow and deformational behavior of articular cartilage. The frictional resistance of the relative motion of the fluid phase with respect to the solid phase is given by a linear diffusive dissipation term. The subchondral bony substrate is represented by an elastic solid. The three-layer model of articular cartilage is chosen because of the known histological, ultrastructural, and biomechanical variations of the tissue properties. The calculated flow field shows that for material properties of normal healthy articular cartilage the tissue creates a naturally lubricated surface. The movement of the interstitial fluid at the surface is circulatory in manner, being exuded in front and near the leading half of the moving surface load and imbibed behind and near the trailing half of the moving load. The flow fields of healthy tissues are capable of sustaining a film of fluid at the articular surface whereas pathological tissues cannot.

1978 ◽  
Vol 100 (3) ◽  
pp. 105-115 ◽  
Author(s):  
M. J. Askew ◽  
V. C. Mow

An inhomogeneous, layered, anisotropic, continuum model of the in-situ articular cartilage-on-bone structure is developed. The model, based on the collagen fibril ultra-structure of the tissue, incorporates an anisotropic (transversely isotropic) layer modeling the superficial tangential zone. The stresses, strains and displacements generated in this model by a static, axisymmetric, parabolically distributed shear-free surface load are determined, using integral transforms and numerical methods. The predicted deformation under the modeled normal physiological loading condition is examined along with deformation changes resulting from abnormal changes in loading geometry and material properties. The results of this analysis of the modeled, layered, inhomogeneous structure, when extrapolated to normal in-vivo conditions, imply that the articular surface is not exposed to continuum tensile stresses, but may be predisposed to possible long term damage due to fatigue by tensile strains. Abnormal decreases in the loaded area of the joint, perhaps due to loss of congruency or degeneration in the joint, cause changes in the magnitude and in the character of the deformational quantities that are detrimental to the long-term survival of the tissue.


Author(s):  
Adam Griebel ◽  
Stephen Trippel ◽  
Corey P. Neu

Osteoarthritis (OA) is a degenerative disease of articular cartilage in synovial joints. The mechanical function of cartilage declines during OA progression, including the softening of the tissue coupled with increased friction and wear [1,2]. Structurally, cartilage wear is regionally nonuniform over the entire articular surface, and load-bearing regions often show more OA severity compared to non-load-bearing regions in the same joint [2].


2015 ◽  
Vol 1753 ◽  
Author(s):  
Md. Mehedi Hasan ◽  
Corina S. Drapaca

ABSTRACTThe brain, a mixture of neural and glia cells, vasculature, and cerebrospinal fluid (CSF), is one of the most complex organs in the human body. To understand brain responses to traumatic injuries and diseases of the central nervous system it is necessary to develop accurate mathematical models and corresponding computer simulations which can predict brain biomechanics and help design better diagnostic and therapeutic protocols. So far brain tissue has been modeled as either a poroelastic mixture saturated by CSF or as a (visco)-elastic solid. However, it is not obvious which model is more appropriate when investigating brain mechanics under certain physiological and pathological conditions. In this paper we study brain’s mechanics by using a Kelvin-Voight (KV) model for a one-phase viscoelastic solid and a Kelvin-Voight-Maxwell-Biot (KVMB) model for a two-phase (solid and fluid) mixture, and explore the limit between these two models. To account for brain’s evolving microstructure, we replace in the equations of motion the classic integer order time derivatives by Caputo fractional order derivatives and thus introduce corresponding fractional KV and KVMB models. As in soil mechanics we use the displacements of the solid phase in the classic (fractional) KVMB model and respectively of the classic (fractional) KV model to define a poroelastic-viscoelastic limit. Our results show that when the CSF and brain tissue in the classic (fractional) KVMB model have similar speeds, then the model is indistinguishable from its equivalent classic (fractional) KV model.


Author(s):  
David M. Pierce ◽  
Werner Trobin ◽  
Siegfried Trattnig ◽  
Horst Bischof ◽  
Gerhard A. Holzapfel

Within the articular cartilage (composed of fluid, electrolytes, chondrocytes, collagen fibers, proteoglycans and other glycoproteins) fibers of predominantly Type II collagen provide tensile strength and stiffness to the solid phase, a proteoglycan gel. Collagen fibers exhibit a high level of structural organization usually consisting of three sub-tissue zones: (i) a superficial tangent zone with fibers which are tangential to the articular surface, (ii) a middle zone with fibers isotropically oriented, (iii) a deep zone with fibers oriented perpendicular to the subchondral bone [1]. Given the importance of this collagen fiber fabric in the mechanical properties of articular cartilage, many destructive and nondestructive experimental methods have been pursued to characterize fiber orientation and density.


Author(s):  
N. A. Bulychev

In this paper, the plasma discharge in a high-pressure fluid stream in order to produce gaseous hydrogen was studied. Methods and equipment have been developed for the excitation of a plasma discharge in a stream of liquid medium. The fluid flow under excessive pressure is directed to a hydrodynamic emitter located at the reactor inlet where a supersonic two-phase vapor-liquid flow under reduced pressure is formed in the liquid due to the pressure drop and decrease in the flow enthalpy. Electrodes are located in the reactor where an electric field is created using an external power source (the strength of the field exceeds the breakdown threshold of this two-phase medium) leading to theinitiation of a low-temperature glow quasi-stationary plasma discharge.A theoretical estimation of the parameters of this type of discharge has been carried out. It is shown that the lowtemperature plasma initiated under the flow conditions of a liquid-phase medium in the discharge gap between the electrodes can effectively decompose the hydrogen-containing molecules of organic compounds in a liquid with the formation of gaseous products where the content of hydrogen is more than 90%. In the process simulation, theoretical calculations of the voltage and discharge current were also made which are in good agreement with the experimental data. The reaction unit used in the experiments was of a volume of 50 ml and reaction capacity appeared to be about 1.5 liters of hydrogen per minute when using a mixture of oxygen-containing organic compounds as a raw material. During their decomposition in plasma, solid-phase products are also formed in insignificant amounts: carbon nanoparticles and oxide nanoparticles of discharge electrode materials.


2020 ◽  
Vol 3 (8) ◽  
pp. 28-34
Author(s):  
N. V. IVANITSKAYA ◽  
◽  
A. K. BAYBULOV ◽  
M. V. SAFRONCHUK ◽  
◽  
...  

In many countries economic policy has been paying increasing attention to the modernization and development of transport infrastructure as a measure of macroeconomic stimulation. Tunnels as an important component of transport infrastructure save a lot of logistical costs. It stimulates increasing freight and passenger traffic as well as the risks of the consequences of unforeseen overloads. The objective of the paper is to suggest the way to reduce operational risks of unforeseen moving load by modeling of the stress-strain state of a transport tunnel under growing load for different conditions and geophysical parameters. The article presents the results of a study of the stress-strain state (SSS) of a transport tunnel exposed to a mobile surface load. Numerical experiments carried out in the ANSYS software package made it possible to obtain diagrams showing the distribution of equivalent stresses (von Mises – stresses) according to the finite element model of the tunnel. The research results give grounds to assert that from external factors the stress state of the tunnel is mainly influenced by the distance to the moving load. The results obtained make it possible to predict in advance the parameters of the stress-strain state in the near-contour area of the tunnel and use the results in the subsequent design of underground facilities, as well as to increase their reliability and operational safety. This investigation gives an opportunity not only to reduce operational risks at the design stage, but to choose an optimal balance between investigation costs and benefits of safety usage period prolongation.


2003 ◽  
Vol 3 ◽  
pp. 266-270
Author(s):  
B.H. Khudjuyerov ◽  
I.A. Chuliev

The problem of the stability of a two-phase flow is considered. The solution of the stability equations is performed by the spectral method using polynomials of Chebyshev. A decrease in the stability region gas flow with the addition of particles of the solid phase. The analysis influence on the stability characteristic of Stokes and Archimedes forces.


2021 ◽  
Vol 6 (1) ◽  
pp. 247301142097570
Author(s):  
Mossub Qatu ◽  
George Borrelli ◽  
Christopher Traynor ◽  
Joseph Weistroffer ◽  
James Jastifer

Background: The intermetatarsal joint between the fourth and fifth metatarsals (4-5 IM) is important in defining fifth metatarsal fractures. The purpose of the current study was to quantify this joint in order to determine the mean cartilage area, the percentage of the articulation that is cartilage, and to give the clinician data to help understand the joint anatomy as it relates to fifth metatarsal fracture classification. Methods: Twenty cadaver 4-5 IM joints were dissected. Digital images were taken and the articular cartilage was quantified by calibrated digital imaging software. Results: For the lateral fourth proximal intermetatarsal articulation, the mean area of articulation was 188 ± 49 mm2, with 49% of the area composed of articular cartilage. The shape of the articular cartilage had 3 variations: triangular, oval, and square. A triangular variant was the most common (80%, 16 of 20 specimens). For the medial fifth proximal intermetatarsal articulation, the mean area of articulation was 143 ± 30 mm2, with 48% of the joint surface being composed of articular cartilage. The shape of the articular surface was oval or triangular. An oval variant was the most common (75%, 15 of 20 specimens). Conclusion: This study supports the notion that the 4-5 IM joint is not completely articular and has both fibrous and cartilaginous components. Clinical Relevance: The clinical significance of this study is that it quantifies the articular surface area and shape. This information may be useful in understanding fifth metatarsal fracture extension into the articular surface and to inform implant design and also help guide surgeons intraoperatively in order to minimize articular damage.


2021 ◽  
Vol 11 (12) ◽  
pp. 5705
Author(s):  
Adrian Stuparu ◽  
Romeo Susan-Resiga ◽  
Alin Bosioc

The present study examines the possibility of using an industrial stirred chemical reactor, originally employed for liquid–liquid mixtures, for operating with two-phase liquid–solid suspensions. It is critical when obtaining a high-quality chemical product that the solid phase remains suspended in the liquid phase long enough that the chemical reaction takes place. The impeller was designed for the preparation of a chemical product with a prescribed composition. The present study aims at finding, using a numerical simulation analysis, if the performance of the original impeller is suitable for obtaining a new chemical product with a different composition. The Eulerian multiphase model was employed along with the renormalization (RNG) k-ε turbulence model to simulate liquid–solid flow with a free surface in a stirred tank. A sliding-mesh approach was used to model the impeller rotation with the commercial CFD code, FLUENT. The results obtained underline that 25% to 40% of the solid phase is sedimented on the lower part of the reactor, depending on the initial conditions. It results that the impeller does not perform as needed; hence, the suspension time of the solid phase is not long enough for the chemical reaction to be properly completed.


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