Sensitivity Analysis of Zwart-Gerber-Belamri Model Parameters on the Numerical Simulation of Francis Runner Cavitation

2018 ◽  
pp. 911-914
Keyword(s):  
Numerical Simulation ◽  
Sensitivity Analysis ◽  
Model Parameters

scholarly journals The Lituya Bay landslide-generated mega-tsunami. Numerical simulation and sensitivity analysis

2018 ◽  
Author(s):  
José Manuel González-Vida ◽  
Jorge Macías ◽  
Manuel Jesús Castro ◽  
Carlos Sánchez-Linares ◽  
Marc de la Asunción ◽  
...  
Keyword(s):  
Numerical Simulation ◽  
Sensitivity Analysis ◽  
Numerical Model ◽  
Shallow Water ◽  
Extreme Event ◽  
Fluid Model ◽  
Model Parameters ◽  
Water Type ◽  
Bathymetric Data ◽  
Run Up

Abstract. The 1958 Lituya Bay landslide-generated mega-tsunami is simulated using the Landslide-HySEA model, a recently developed finite volume Savage-Hutter Shallow Water coupled numerical model. Two factors are crucial if the main objective of the numerical simulation is to reproduce the maximal run-up, with an accurate simulation of the inundated area and a precise re-creation of the known trimline of the 1958 mega-tsunami of Lituya Bay. First, the accurate reconstruction of the initial slide. Then, the choice of a suitable coupled landslide-fluid model able to reproduce how the energy released by the landslide is transmitted to the water and then propagated. Given the numerical model, the choice of parameters appears to be a point of major importance, this leads us to perform a sensitivity analysis. Based on public domain topo-bathymetric data, and on information extracted from the work of Miller (1960), an approximation of Gilbert Inlet topo-bathymetry was set up and used for the numerical simulation of the mega-event. Once optimal model parameters were set, comparisons with observational data were performed in order to validate the numerical results. In the present work, we demonstrate that a shallow water type of model is able to accurately reproduce such an extreme event as the Lituya Bay mega-tsunami. The resulting numerical simulation is one of the first successful attempts (if not the first) at numerically reproducing in detail the main features of this event in a realistic 3D basin geometry, where no smoothing or other stabilizing factors in the bathymetric data are applied.

scholarly journals The Lituya Bay landslide-generated mega-tsunami – numerical simulation and sensitivity analysis

2019 ◽  
Vol 19 (2) ◽  
pp. 369-388 ◽  
Author(s):  
José Manuel González-Vida ◽  
Jorge Macías ◽  
Manuel Jesús Castro ◽  
Carlos Sánchez-Linares ◽  
Marc de la Asunción ◽  
...  
Keyword(s):  
Numerical Simulation ◽  
Sensitivity Analysis ◽  
Numerical Model ◽  
Shallow Water ◽  
Extreme Event ◽  
Fluid Model ◽  
Model Parameters ◽  
Water Type ◽  
Bathymetric Data ◽  
Run Up

Abstract. The 1958 Lituya Bay landslide-generated mega-tsunami is simulated using the Landslide-HySEA model, a recently developed finite-volume Savage–Hutter shallow water coupled numerical model. Two factors are crucial if the main objective of the numerical simulation is to reproduce the maximal run-up with an accurate simulation of the inundated area and a precise recreation of the known trimline of the 1958 mega-tsunami of Lituya Bay: first, the accurate reconstruction of the initial slide and then the choice of a suitable coupled landslide–fluid model able to reproduce how the energy released by the landslide is transmitted to the water and then propagated. Given the numerical model, the choice of parameters appears to be a point of major importance, which leads us to perform a sensitivity analysis. Based on public domain topo-bathymetric data, and on information extracted from the work of Miller (1960), an approximation of Gilbert Inlet topo-bathymetry was set up and used for the numerical simulation of the mega-event. Once optimal model parameters were set, comparisons with observational data were performed in order to validate the numerical results. In the present work, we demonstrate that a shallow water type of model is able to accurately reproduce such an extreme event as the Lituya Bay mega-tsunami. The resulting numerical simulation is one of the first successful attempts (if not the first) at numerically reproducing, in detail, the main features of this event in a realistic 3-D basin geometry, where no smoothing or other stabilizing factors in the bathymetric data are applied.

scholarly journals A Sensitivity Analysis of the SPACSYS Model

Agriculture ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 624
Author(s):  
Yan Shan ◽  
Mingbin Huang ◽  
Paul Harris ◽  
Lianhai Wu
Keyword(s):  
Sensitivity Analysis ◽  
Wheat Yield ◽  
Climatic Conditions ◽  
Water Dynamics ◽  
Ecological Modelling ◽  
Soil Conditions ◽  
Model Parameters ◽  
Nutrient Inputs ◽  
Nutrient Pool ◽  
Wheat Field

A sensitivity analysis is critical for determining the relative importance of model parameters to their influence on the simulated outputs from a process-based model. In this study, a sensitivity analysis for the SPACSYS model, first published in Ecological Modelling (Wu, et al., 2007), was conducted with respect to changes in 61 input parameters and their influence on 27 output variables. Parameter sensitivity was conducted in a ‘one at a time’ manner and objectively assessed through a single statistical diagnostic (normalized root mean square deviation) which ranked parameters according to their influence of each output variable in turn. A winter wheat field experiment provided the case study data. Two sets of weather elements to represent different climatic conditions and four different soil types were specified, where results indicated little influence on these specifications for the identification of the most sensitive parameters. Soil conditions and management were found to affect the ranking of parameter sensitivities more strongly than weather conditions for the selected outputs. Parameters related to drainage were strongly influential for simulations of soil water dynamics, yield and biomass of wheat, runoff, and leaching from soil during individual and consecutive growing years. Wheat yield and biomass simulations were sensitive to the ‘ammonium immobilised fraction’ parameter that related to soil mineralization and immobilisation. Simulations of CO2 release from the soil and soil nutrient pool changes were most sensitive to external nutrient inputs and the process of denitrification, mineralization, and decomposition. This study provides important evidence of which SPACSYS parameters require the most care in their specification. Moving forward, this evidence can help direct efficient sampling and lab analyses for increased accuracy of such parameters. Results provide a useful reference for model users on which parameters are most influential for different simulation goals, which in turn provides better informed decision making for farmers and government policy alike.

scholarly journals Global Sensitivity Analysis of a Homogenized Constrained Mixture Model of Arterial Growth and Remodeling

2021 ◽  
Author(s):  
Sebastian Brandstaeter ◽  
Sebastian L. Fuchs ◽  
Jonas Biehler ◽  
Roland C. Aydin ◽  
Wolfgang A. Wall ◽  
...  
Keyword(s):  
Sensitivity Analysis ◽  
Global Sensitivity Analysis ◽  
Model Parameters ◽  
Computational Studies ◽  
Growth And Remodeling ◽  
Global Sensitivity ◽  
Output Variability ◽  
Constrained Mixture ◽  
The One ◽  
Influential Parameters

AbstractGrowth and remodeling in arterial tissue have attracted considerable attention over the last decade. Mathematical models have been proposed, and computational studies with these have helped to understand the role of the different model parameters. So far it remains, however, poorly understood how much of the model output variability can be attributed to the individual input parameters and their interactions. To clarify this, we propose herein a global sensitivity analysis, based on Sobol indices, for a homogenized constrained mixture model of aortic growth and remodeling. In two representative examples, we found that 54–80% of the long term output variability resulted from only three model parameters. In our study, the two most influential parameters were the one characterizing the ability of the tissue to increase collagen production under increased stress and the one characterizing the collagen half-life time. The third most influential parameter was the one characterizing the strain-stiffening of collagen under large deformation. Our results suggest that in future computational studies it may - at least in scenarios similar to the ones studied herein - suffice to use population average values for the other parameters. Moreover, our results suggest that developing methods to measure the said three most influential parameters may be an important step towards reliable patient-specific predictions of the enlargement of abdominal aortic aneurysms in clinical practice.

scholarly journals Gaussian Processes Proxy Model with Latent Variable Models and Variogram-Based Sensitivity Analysis for Assisted History Matching

Energies ◽  
2020 ◽  
Vol 13 (17) ◽  
pp. 4290
Author(s):  
Dongmei Zhang ◽  
Yuyang Zhang ◽  
Bohou Jiang ◽  
Xinwei Jiang ◽  
Zhijiang Kang
Keyword(s):  
Sensitivity Analysis ◽  
Gaussian Processes ◽  
Latent Variable ◽  
History Matching ◽  
Latent Variable Models ◽  
High Dimensional ◽  
Model Parameters ◽  
Variable Model ◽  
Assisted History Matching ◽  
Proxy Models

Reservoir history matching is a well-known inverse problem for production prediction where enormous uncertain reservoir parameters of a reservoir numerical model are optimized by minimizing the misfit between the simulated and history production data. Gaussian Process (GP) has shown promising performance for assisted history matching due to the efficient nonparametric and nonlinear model with few model parameters to be tuned automatically. Recently introduced Gaussian Processes proxy models and Variogram Analysis of Response Surface-based sensitivity analysis (GP-VARS) uses forward and inverse Gaussian Processes (GP) based proxy models with the VARS-based sensitivity analysis to optimize the high-dimensional reservoir parameters. However, the inverse GP solution (GPIS) in GP-VARS are unsatisfactory especially for enormous reservoir parameters where the mapping from low-dimensional misfits to high-dimensional uncertain reservoir parameters could be poorly modeled by GP. To improve the performance of GP-VARS, in this paper we propose the Gaussian Processes proxy models with Latent Variable Models and VARS-based sensitivity analysis (GPLVM-VARS) where Gaussian Processes Latent Variable Model (GPLVM)-based inverse solution (GPLVMIS) instead of GP-based GPIS is provided with the inputs and outputs of GPIS reversed. The experimental results demonstrate the effectiveness of the proposed GPLVM-VARS in terms of accuracy and complexity. The source code of the proposed GPLVM-VARS is available at https://github.com/XinweiJiang/GPLVM-VARS.

scholarly journals Cost-effectiveness of TAS-102 plus bevacizumab versus TAS-102 monotherapy in patients with metastatic colorectal cancer

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Kiyoaki Sugiura ◽  
Yuki Seo ◽  
Takayuki Takahashi ◽  
Hideyuki Tokura ◽  
Yasuhiro Ito ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Health Care ◽  
Sensitivity Analysis ◽  
Cost Effectiveness ◽  
Combination Therapy ◽  
Metastatic Colorectal Cancer ◽  
Cost Effective ◽  
Model Parameters ◽  
Combination Regimen ◽  
The Cost

Abstract Background TAS-102 plus bevacizumab is an anticipated combination regimen for patients who have metastatic colorectal cancer. However, evidence supporting its use for this indication is limited. We compared the cost-effectiveness of TAS-102 plus bevacizumab combination therapy with TAS-102 monotherapy for patients with chemorefractory metastatic colorectal cancer. Method Markov decision modeling using treatment costs, disease-free survival, and overall survival was performed to examine the cost-effectiveness of TAS-102 plus bevacizumab combination therapy and TAS-102 monotherapy. The Japanese health care payer’s perspective was adopted. The outcomes were modeled on the basis of published literature. The incremental cost-effectiveness ratio (ICER) between the two treatment regimens was the primary outcome. Sensitivity analysis was performed and the effect of uncertainty on the model parameters were investigated. Results TAS-102 plus bevacizumab had an ICER of $21,534 per quality-adjusted life-year (QALY) gained compared with TAS-102 monotherapy. Sensitivity analysis demonstrated that TAS-102 monotherapy was more cost-effective than TAS-102 and bevacizumab combination therapy at a willingness-to-pay of under $50,000 per QALY gained. Conclusions TAS-102 and bevacizumab combination therapy is a cost-effective option for patients who have metastatic colorectal cancer in the Japanese health care system.

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