How Well Does a Musculoskeletal Model Predict GH-Joint Contact Forces? Comparison With In-Vivo Data

Author(s):  
A. Asadi Nikooyan ◽  
H. E. J. Veeger ◽  
P. Westerhoff ◽  
F. Graichen ◽  
G. Bergmann ◽  
...  

The Delft Shoulder and Elbow Model (DSEM), a large-scale musculoskeletal model, allows for estimation of individual muscle and joint reaction forces in the shoulder and elbow complex. Although the model has been qualitatively verified previously using EMG signals, quantitative validation has not yet been feasible. In this paper we report on the validation of the DSEM by comparing the GH-joint contact forces estimated by the DSEM with the in-vivo forces measured by a recently developed instrumented shoulder endoprosthesis, capable of measuring the glenohumeral (GH) joint contact forces in-vivo [1]. To validate the model, two patients with instrumented shoulder hemi-arthroplasty were measured. The measurement process included the collection of motion data as well as in-vivo joint reaction forces. Segment and joint angles were used as the model inputs to estimate the GH-joint contact forces. The estimated and recorded GH-joint contact forces for Range of Motion (RoM) and force tasks were compared based on the magnitude of the resultant forces. The results show that the estimated force follows the measured force for abduction and anteflexion motions up to 80 and 50 degrees arm elevations, respectively, while they show different behaviors for angles above 90 degrees (decrease is estimated but increase is measured). The DSEM underestimates the peak force for RoM (up to 38% for abduction motion and 64% for anteflexion motion), while overestimates the peak forces (up to 90%) for most directions of performing the force tasks.

2018 ◽  
Vol 140 (7) ◽  
Author(s):  
Quental Carlos ◽  
Azevedo Margarida ◽  
Ambrósio Jorge ◽  
Gonçalves S. B. ◽  
Folgado João

Abstract Most dynamic simulations are based on inverse dynamics, being the time-dependent physiological nature of the muscle properties rarely considered due to numerical challenges. Since the influence of muscle physiology on the consistency of inverse dynamics simulations remains unclear, the purpose of the present study is to evaluate the computational efficiency and biological validity of four musculotendon models that differ in the simulation of the muscle activation and contraction dynamics. Inverse dynamic analyses are performed using a spatial musculoskeletal model of the upper limb. The muscle force-sharing problem is solved for five repetitions of unloaded and loaded motions of shoulder abduction and shoulder flexion. The performance of the musculotendon models is evaluated by comparing muscle activation predictions with electromyography (EMG) signals, measured synchronously with motion for 11 muscles, and the glenohumeral joint reaction forces estimated numerically with those measured in vivo. The results show similar muscle activations for all muscle models. Overall, high cross-correlations are computed between muscle activations and the EMG signals measured for all movements analyzed, which provides confidence in the results. The glenohumeral joint reaction forces estimated compare well with those measured in vivo, but the influence of the muscle dynamics is found to be negligible. In conclusion, for slow-speed, standard movements of the upper limb, as those studied here, the activation and musculotendon contraction dynamics can be neglected in inverse dynamic analyses without compromising the prediction of muscle and joint reaction forces.


2019 ◽  
Author(s):  
◽  
Swithin Samuel Razu

"The goal of this dissertation is to develop a musculoskeletal model and corroborate model predictions to experimentally measured in vivo knee contact forces, in order to study the biomechanical consequences of two different total knee arthroplasty designs. The two main contributions of this dissertation are: (1) Corroboration to experimental data: The development of an EMG-driven, full-body, musculoskeletal model with subject-specific leg geometries including deformable contacts, ligaments, 6DOF knee joint, and a shoe-floor model that can concurrently predict muscle forces, ligament forces, and joint contact forces. Model predictions of tibiofemoral joint contact forces were evaluated against the subject-specific in vivo measurements from the instrumented TKR for three distinctly different styles of over ground gait. (2) Virtual surgery in TKA: The musculoskeletal modeling methodology was then used to develop a model for one healthy participant with a native knee and then virtually replacing the native knee with fixed-bearing and mobile-bearing total knee arthroplasty designs performing gait and step-up tasks. This approach minimized the biomechanical impact of variations in sex, geometry, implant size, design and positioning, ligament location and tension, and muscle forces found across patients. The differences in biomechanics were compared for the two designs. 1.2 Significance of this Research The world health organization ranks musculoskeletal disorders as the second largest contributor to disability worldwide. Conservative estimates put the national cost of direct care for musculoskeletal disease at $212.7 billion a year [1]. Many people who suffer from neuromuscular or musculoskeletal diseases may benefit from the insights gained from surgery simulations, since musculoskeletal reconstructions are commonly performed on these individuals. Improved surgical outcomes will benefit these individuals not only in the short-term, but also in the long-term, since their future rehabilitation needs may be reduced. For example, although total knee arthroplasty is a common surgical procedure for the treatment of osteoarthritis with over 700,000 procedures performed each year [2], many patients are unhappy with the ultimate results [3]. Ten to 30% of patients report [4] pain, dissatisfaction with function, and the need for further surgery such as revision after the initial surgery resulting in costs exceeding $11 billion [5]. Potentially, simulation studies that quantify the important biomechanical variables will reduce the need for revision surgeries in patients."--Introduction.


Author(s):  
Koichi Kobayashi ◽  
Guoan Li

The load transfer mechanics across the patellofemoral (PF) joint during weight-bearing conditions is important for treatment of the knee pathology, such as knee OA, ACL deficiency as well as TKA. Many studies have characterized the PF joint reaction forces using equilibriums of the quadriceps and ground reaction forces at the knee joint [1,2,3]. However, this simplification does not consider other muscle function as well as 3D knee joint contact location when calculate moment arms of the involved forces.


2016 ◽  
Vol 138 (2) ◽  
Author(s):  
Florent Moissenet ◽  
Laurence Chèze ◽  
Raphaël Dumas

While recent literature has clearly demonstrated that an extensive personalization of the musculoskeletal models was necessary to reach high accuracy, several components of the generic models may be further investigated before defining subject-specific parameters. Among others, the choice in muscular geometry and thus the level of muscular redundancy in the model may have a noticeable influence on the predicted musculotendon and joint contact forces. In this context, the aim of this study was to investigate if the level of muscular redundancy can contribute or not to reduce inaccuracies in tibiofemoral contact forces predictions. For that, the dataset disseminated through the Sixth Grand Challenge Competition to Predict In Vivo Knee Loads was applied to a versatile 3D lower limb musculoskeletal model in which two muscular geometries (i.e., two different levels of muscular redundancy) were implemented. This dataset provides tibiofemoral implant measurements for both medial and lateral compartments and thus allows evaluation of the validity of the model predictions. The results suggest that an increase of the level of muscular redundancy corresponds to a better accuracy of total tibiofemoral contact force whatever the gait pattern investigated. However, the medial and lateral contact forces ratio and accuracy were not necessarily improved when increasing the level of muscular redundancy and may thus be attributed to other parameters such as the location of contact points. To conclude, the muscular geometry, among other components of the generic model, has a noticeable impact on joint contact forces predictions and may thus be correctly chosen even before trying to personalize the model.


Author(s):  
Gang Wang ◽  
Zhaohui Qi

In this study, a drive system connected by rolling bearings and double universal joints is modeled as a closed-loop multibody system. Because of the existence of redundant constraints, the joint reaction forces cannot be determined uniquely through dynamic analysis. Based on the physical mechanism where the joint reaction forces are the resultants of contact forces at the joint definition point, a methodology of frictionless contact analysis is presented to identify joint reaction forces. In terms of D’Alembert’s principle, the dynamic equations of constrained multibody systems are equivalent to the equilibrium equations of all bodies composed of joint contact forces, externally applied forces, and inertial forces. The equivalent equilibrium equations provide a set of complementary equations to identify the contact positions and contact forces in the rolling bearings and double universal joints. The drive system is also simulated using ADAMS software, where all the joints are released and the corresponding constraint functions are replaced by the impact forces between the joint components. Some conclusions are obtained through the comparison of numerical examples between the proposed method and the ADAMS model. In the double universal joints, the equations are adequate and independent, which results in that the corresponding contact positions and contact forces can be solved uniquely. Then, the correlation between the data produced by these two models is acceptable in the engineering practices. Furthermore, contact details in the double universal joints can be obtained without the calculation of the relative motion between the cross-pin and yokes. However, the reaction forces in the rolling bearings are indeterminate due to that their complementary equations are not independent. The proposed method has high efficiency and acceptable precision.


2020 ◽  
Vol 73 (1) ◽  
pp. 59-72
Author(s):  
Jingguang Qian ◽  
Yiling Mao ◽  
Xiao Tang ◽  
Zhaoxia Li ◽  
Chen Wen ◽  
...  

AbstractIn order to fully understand contact dynamics on a trampoline, a simulation approach using a musculoskeletal model coupled with a dynamic model of the trampoline is essential. The purpose of the study was to examine dynamics and selected lower extremity muscle forces in a landing and jumping movement on a trampoline, using a combination of finite element modeling and musculoskeletal modeling. The rigid frame of the trampoline was modeled in ADAMS and coupled with a finite element model of the elastic trampoline net surface in ANSYS. A musculoskeletal model of an elite trampoline athlete was further developed in LifeMod and combined with the finite element model of the trampoline. The results showed that the peak trampoline reaction forces (TRF) were 3400 N (6.6 BW) and 2900 N (5.6 BW) for the left and right limb, respectively. The right hip, knee and ankle joint reaction forces reached the maximum between 3000-4000 N (5.8 – 7.7 BW). The gluteus maximum and quadriceps reached the maximum muscle force of 380 N (0.7 BW) and 780 N (1.5 BW), respectively. Asymmetric loading patterns between left and right TRFs and lower extremities joint reaction forces were observed due to the need to generate the rotational movement during the takeoff. The observed rigid and erect body posture suggested that the hip and knee extensors played important roles in minimizing energy absorption and maximizing energy generation during the trampoline takeoff.


2020 ◽  
Vol 21 (6) ◽  
pp. 623
Author(s):  
Joanne Becker ◽  
Emmanuel Mermoz ◽  
Jean-Marc Linares

In biomechanical field, several studies used OpenSim software to compute the joint reaction forces from kinematics and ground reaction forces measurements. The bio-inspired joints design and their manufacturing need the usage of mechanical modeling and simulation software tools. This paper proposes a new hybrid methodology to determine biological joint reaction forces from in vivo measurements using both biomechanical and mechanical engineering softwares. The methodology has been applied to the horse forelimb joints. The computed joint reaction forces results would be compared to the results obtained with OpenSim in a previous study. This new hybrid model used a combination of measurements (bone geometry, kinematics, ground reaction forces…) and also OpenSim results (muscular and ligament forces). The comparison between the two models showed values with an average difference of 8% at trotting and 16% at jumping. These differences can be associated with the differences between the modelling strategies. Despite these differences, the mechanical modeling method allows the computation of advanced simulations to handle contact conditions in joints. In future, the proposed mechanical engineering methodology could open the door to define a biological digital twin of a quadruped limb including the real geometry modelling of the joint.


Micromachines ◽  
2021 ◽  
Vol 12 (11) ◽  
pp. 1430
Author(s):  
Elliott C. Leinauer ◽  
Hyunmin M. Kim ◽  
Jae W. Kwon

This work presents a polymer-based tactile capacitive sensor capable of measuring joint reaction forces of reverse total shoulder arthroplasty (RTSA). The capacitive sensor contains a polydimethylsiloxane (PDMS) dielectric layer with an array of electrodes. The sensor was designed in such a way that four components of glenohumeral contact forces can be quantified to help ensure proper soft tissue tensioning during the procedure. Fabricated using soft lithography, the sensor has a loading time of approximately 400 ms when a 14.13 kPa load is applied and has a sensitivity of 1.24 × 10−3 pF/kPa at a load of 1649 kPa. A replica RTSA prothesis was 3D printed, and the sensor was mounted inside the humeral cap. Four static right shoulder positions were tested, and the results provided an intuitive graphical description of the pressure distribution across four quadrants of the glenohumeral joint contact surface. It may help clinicians choose a right implant size and offset that best fit a patient’s anatomy and reduce postoperative biomechanical complications such as dislocation and stress fracture of the scapula.


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