Non-Invasive Temperature Measurement for Polyimid-Based Microstructured Devices

Author(s):  
Jens Bobers ◽  
Felix Reichmann ◽  
Jakob Zimmermann ◽  
Norbert Kockmann

Abstract Besides the common benefits of micro-structured reactors such as enhanced mass and heat transfer caused by a high specific surface and enhanced mixing, they have also drawbacks due to their tiny dimensions. Non-invasive temperature measurement is an important issue for micro process engineering regarding to process control and safety issues. High resolution and robustness are requirements which should be met by the temperature measuring method. Thin film technology combines the possibility to manufacture micro scaled structures with great flexibility in choosing material and geometry of the structures. Layers of aluminum with a thickness in nanometer range are deposited on flexible polyimide foil and structured lithographically to obtain electrical conductor tracks which are used as temperature sensors based on their electrical resistance. The produced temperature sensors were calibrated in the range from 20 to 70 °C and the accuracy of the sensors was checked.

1995 ◽  
Vol 73 (04) ◽  
pp. 592-596 ◽  
Author(s):  
Sabina Villalta ◽  
Paolo Prandoni ◽  
Alberto Cogo ◽  
Paola Bagatella ◽  
Andrea Piccioli ◽  
...  

SummaryBackground. Despite the availability of several diagnostic methods for the detection of deep-vein thrombosis (DVT), the identification of previous episodes of DVT remains a diagnostic challenge.Study objective. To assess the reliability of a combination of a standardized clinical score with three non-invasive tests: compression ultrasonography (CUS), Doppler ultrasound (DUS), and photoplethysmography (PPG), in determining the presence or the absence of previous proximal DVT.Methods. One hundred consecutive unselected outpatients were identified, who had undergone contrast venography six to nine years previously because of the clinical suspicion of DVT (confirmed in 43). They were blindly reinvestigated by a panel of trained operators unaware of venography results. They underwent a clinical evaluation of the lower limb, by applying a standardized score to five symptoms and six signs (grading each item from 0 to 3); a PPG test to determine the venous refilling time; a DUS test to determine the venous reflux separately in the common femoral and the popliteal vein; and a CUS test to determine vein compressibility in the same regions.Results. An abnormal CUS test and/or the demonstration of venous reflux in the popliteal region and/or a high clinical score (≥ 8) identified twenty-four of the 43 (56%) DVT + patients with a specificity of 89%. The combination of normal CUS with the absence of venous reflux in both the common femoral and popliteal vein and a low clinical score excluded previous thrombosis in 45 (79%) of the 57 DVT- patients (negative predictive value, 78%). Abnormal venous reflux in the isolated common femoral vein did not reliably predict the presence or absence of previous DVT. However, this occurred in only 13 (13%) patients. The PPG determination of venous refilling time did not improve the results obtained with the other tests.Conclusions. The combination of a standardized clinical evaluation with the results of CUS and DUS can reliably diagnose or exclude previous proximal-vein thrombosis in almost 90% of patients with previous episodes of suspected DVT.


2020 ◽  
pp. 49-52
Author(s):  
Trine Aabo Andersen

A new fast measuring method for process optimization of sucrose crystallization using image analysis based on high quality images and algorithms is introduced. With the mobile, non-invasive at-line system all steps of the sucrose crystallization can be measured to determine the crystal size distribution. The image analysis system is easy to operate and is as well an efficient laboratory solution with user-friendly and customized software. In comparison to sieve analysis, image analyses performed with the ParticleTech Solution have been proven to be reliable.


2020 ◽  
Vol 87 (9) ◽  
pp. 553-563
Author(s):  
Jörg Gebhardt ◽  
Guruprasad Sosale ◽  
Subhashish Dasgupta

AbstractAccurate and responsive non-invasive temperature measurements are enablers for process monitoring and plant optimization use cases in the context of Industry 4.0. If their performance is proven for large classes of applications, such measurement principles can replace traditional invasive measurements. In this paper we describe a two-step model to estimate the process temperature from a pipe surface temperature measurement. This static case model is compared to and enhanced by computational fluid dynamic (CFD) calculations to predict transient situations. The predictions of the approach are validated by means of controlled experiments in a laboratory environment. The experimental results demonstrate the efficacy of the model, the responsiveness of the pipe surface temperature, and that state of the art industrial non-invasive sensors can achieve the performance of invasive thermowells. The non-invasive sensors are then used to demonstrate the performance of the model in industrial applications for cooling fluids and steam.


2021 ◽  
Vol 19 (1) ◽  
pp. 15-21
Author(s):  
S. L. Morozov ◽  
◽  
V. V. Dlin ◽  

The global task of the recent decade is to search for clinical and laboratory markers accurately showing a patient’s reaction to steroid therapy and other immunosuppressive drugs. It is important the applied methods and tests to be non-invasive and simple to use. The article considers various biomarkers used to verify the type of nephrotic syndrome depending on the sensitivity to steroid therapy. Besides the common markers, which are used in clinical practice or have shown a significant result, the work highlights the molecular- genetic markers of resistance to steroid therapy, which are of special clinical importance today. Also, the article presents authors’ own results in diagnosing the steroid resistance of the primary nephrotic syndrome.


2012 ◽  
Vol 38 (6) ◽  
pp. 523-530 ◽  
Author(s):  
Susan Barnason ◽  
Jennifer Williams ◽  
Jean Proehl ◽  
Carla Brim ◽  
Melanie Crowley ◽  
...  

2022 ◽  
pp. 41-66
Author(s):  
Muhammad Haseeb Ahmad ◽  
Amna Sahar ◽  
Muhammad Imran ◽  
Muhammad Kamran Khan ◽  
Rabia Shabir Ahmad ◽  
...  

In this modern era of digitalization and consumer awareness regarding food safety issues, it has become important to build proper strategies that can ensure the quality and safety of the food items from farm to forks. People love to eat at restaurants not only during business meetings but also with their family for fun and entertainment. The choice and safety of the food is vital to attract the consumer in this competitive environment. Previously, conventional methods have been employed for assurance of quality and safety parameters of the food. But in this modern era, there are many potential alternatives that can serve the purpose rapidly and non-destructively. Hence, this chapter describes the rapid and non-destructive methodologies such as fluorescence, NIRS, MIR, and Raman spectroscopy that can be used for the food safety evaluations.


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