An Investigation on the Minimum Inventory of Human System Interfaces for Plant’s Safe Operation

2010 ◽  
Author(s):  
Chih-Wei Yang ◽  
Tzu-Chung Yenn ◽  
Tsung-Chieh Cheng ◽  
Ming-Huei Chen ◽  
Tung-Ming Wu
Keyword(s):  
Safe Operation ◽  
Human System ◽  
Analytic Procedure ◽  
Digital Instrumentation ◽  
The Status ◽  
Design Requirements ◽  
Failure Conditions ◽  
Safe Condition ◽  
System Interfaces ◽  
And Control

This paper investigates the minimum inventory (MI) of human system interfaces (HSIs) (i.e. alarms, controls, and displays) for plant’s safe operation and represents the analytic procedure on the MI of HSIs developed for the digital instrumentation and control (I&C) equipments in the main control room (MCR). The MI of HSIs in the MCR indicates the HSIs that the operator always needs available to: (1) monitor the status; (2) perform and confirm a reactor trip; (3) perform and confirm a controlled shutdown of the reactor; (4) actuate safety related systems; (5) analyze failure conditions of the normal HSIs; (6) implement the plant’s emergency operating procedures (EOPs); (7) bring the plant to a safe condition; (8) carry out those operator actions shown to be risk important by the probabilistic risk assessment (PRA). The proposed analytic procedure on the MI of HSIs in this study can be used to (1) identify the MI of HSIs and their design requirements; and (2) addresses design requirements and implementation for the MI of HSIs. The contribution of this study is to describe the MI of HSIs needed to implement the plant’s EOPs, to bring the plant to a safe condition, and to carry out those operator actions shown to be risk important by the PRA.

Efficacy of Ovsynch and Ovsynch Plus Protocol for Improvement of Fertility in Postpartum Sahiwal Cows

2019 ◽  
Vol 14 (04) ◽  
Author(s):  
J. P. Lakher ◽  
M. K. Awasthi ◽  
J. R. Khan ◽  
M. R. Poyam
Keyword(s):  
Fixed Time ◽  
Conception Rate ◽  
Control Group ◽  
Group Iii ◽  
Treatment Groups ◽  
Group I ◽  
Early Postpartum ◽  
The Status ◽  
Sahiwal Cows ◽  
And Control

The present study was conducted to investigate the efficacy of Ovsynch and Ovsynch plus protocol in postpartum (day 60) Sahiwal cows (n=18). Animals were randomly divided into three equal groups, viz., Ovsynch group Ovsynch plus group and Control group. Animals of group I (n = 6) were treated with traditional Ovsynch protocol. The animals (n = 6) of group II were treated with Ovsynch plus protocol which consisted of an initial intramuscular injection of eCG (Folligon) @ 250 IU on day 60 postpartum followed 3 days later by GPG (Ovsynch) protocol. In group-III Control, no treatment was given to animals (n = 6). Treated animals were inseminated at a fixed time between 14 and 20 hrs after second GnRH injection, irrespective of estrus detection. Blood samples were collected from each animal on days 50 and 60 postpartum to determine the status of cyclicity in animals based on serum concentrations of progesterone (P4). A third blood sample was collected on the day of prostaglandin treatment to determine the response of first GnRH injection. Four animals each were cyclic, and two were acyclic in both treatment groups. Four animals each responded to first GnRH treatment in both treatment groups. Similarly, two animals each got conceived giving conception rate of 50% (2/4) in each treatment. In the control group, one out of 6 animals got conceived yielding 16.66 % conception rate (1/6) during the study period. It may be thus concluded that Ovsynch and Ovsynch plus protocol may be used during the early postpartum period to improve the reproductive efficiency in postpartum Sahiwal cows.

scholarly journals Post hoc analysis of ellipsoid zone changes beyond the central subfield in symptomatic vitreomacular adhesion patients from the OASIS trial

2021 ◽  
Vol 6 (1) ◽  
pp. e000648
Author(s):  
Swetha Bindu Velaga ◽  
Muneeswar Gupta Nittala ◽  
Michael S Ip ◽  
Luc Duchateau ◽  
SriniVas R Sadda
Keyword(s):  
Time Course ◽  
Vitreomacular Adhesion ◽  
Ellipsoid Zone ◽  
Post Hoc Analysis ◽  
Link Type ◽  
Phase Iiib ◽  
The Status ◽  
Registration Number ◽  
Post Hoc ◽  
And Control

Background/aimsOASIS is a Phase IIIb trial (NCT01429441) assessing long-term outcomes in subjects with symptomatic vitreomacular adhesion (VMA). The purpose of this study is to report on the frequency, severity, location and time course of ellipsoid zone (EZ) alterations in ocriplasmin-treated and sham control eyes in the OASIS study.Methods220 patients (146 ocriplasmin, 74 sham) subjects with VMA were enrolled in this masked post hoc analysis phase IIIb, randomised, sham-controlled double-masked multicentre clinical trial. A masked post hoc analysis of OCT images was performed at the Doheny Image Reading Center from subjects enrolled in the OASIS trial. The status of the EZ band was assessed in three different macular regions: the central subfield (CS) (≤1 mm diameter), the parafoveal area (PAA) (>1 to ≤3 mm) and the perifoveal area (PEA) (>3 to ≤6 mm). The EZ band was rated as normal/intact, full thickness macular hole (FTMH), abnormal but continuous, discontinuous/disrupted or absent at visits from baseline (pretreatment) to week 1 (day 7), month 1 (day 28), month 3, month 6, month 12 and the final follow-up at month 24. EZ band status was compared in both study and control eyes.ResultsA total of 208 patients (138 ocriplasmin, 70 sham) were included in this analysis. At baseline, FTMH was present in 48.6%, 8.0%, 0% and 52.8%, 2.9%, 0% in the CS, PAA and PEA of the ocriplasmin and sham groups, respectively. The EZ was graded to be abnormal but continuous, discontinuous/disrupted or absent at Baseline in 21.0%, 4.3%, 2.8% in the CS, PAA and PEA, respectively, of the ocriplasmin group; and 12.9%, 10.0%, 4.3% in the CS, PAA and PEA of the sham group. For the ocriplasmin group in the PAA, this frequency increased to 6.6% at week 1, was 9.8% at month 1, but improved to 3.8% at month 3, and remained stable to 1.6% at month 24. These differences, however, were not statistically significant.ConclusionsOcriplasmin treatment for symptomatic VMA was associated with EZ abnormalities in a small percentage of patients that was best assessed in regions (PEA) relatively unaffected by the VM interface disease at baseline. The EZ abnormalities were apparent by week 1, persisted at month 1, and appeared to resolve in the majority of cases by month 3.Trial registration numberNCT01429441

Perceived Social Mobility and Political Trust in China

2015 ◽  
Vol 14 (4) ◽  
pp. 315-336 ◽  
Author(s):  
Zhenhua Su ◽  
Yang Cao ◽  
Jingkai He ◽  
Waibin Huang
Keyword(s):  
Economic Growth ◽  
Social Mobility ◽  
Social Order ◽  
Political Trust ◽  
Traditional Culture ◽  
Status Quo ◽  
World Values Survey ◽  
Reform Era ◽  
The Status ◽  
And Control

Existing studies have traced China’s high political trust to three sources: traditional culture, the state’s success in fostering economic growth, and ideological propaganda. We identify a fourth source: perceived social mobility. We argue that when people perceive a reasonable chance for upward mobility based on personal initiatives and efforts, the status quo becomes more justifiable because individuals are responsible for their own successes and failures. Perceived social mobility thus instills a sense of optimism and fairness and exonerates the regime from many blames, thereby enhancing political trust. Regression analysis of the China portion of the 2007 World Values Survey data shows that respondents who saw themselves as having choices and control in life were indeed more likely to trust the ruling communist party. The respondents’ overall level of perceived social mobility is also high, which is consistent with the massive shake-up of the preexisting social order in China’s reform era.

Overview of Path-Planning and Obstacle Avoidance Algorithms for UAVs: A Comparative Study

2018 ◽  
Vol 06 (02) ◽  
pp. 95-118 ◽  
Author(s):  
Mohammadreza Radmanesh ◽  
Manish Kumar ◽  
Paul H. Guentert ◽  
Mohammad Sarim
Keyword(s):  
Path Planning ◽  
Comparative Study ◽  
Operating Conditions ◽  
Computational Time ◽  
Safe Operation ◽  
Sense And Avoid ◽  
Planning Algorithms ◽  
And Control ◽  
Global And Local ◽  
Further Development

Unmanned aerial vehicles (UAVs) have recently attracted the attention of researchers due to their numerous potential civilian applications. However, current robot navigation technologies need further development for efficient application to various scenarios. One key issue is the “Sense and Avoid” capability, currently of immense interest to researchers. Such a capability is required for safe operation of UAVs in civilian domain. For autonomous decision making and control of UAVs, several path-planning and navigation algorithms have been proposed. This is a challenging task to be carried out in a 3D environment, especially while accounting for sensor noise, uncertainties in operating conditions, and real-time applicability. Heuristic and non-heuristic or exact techniques are the two solution methodologies that categorize path-planning algorithms. The aim of this paper is to carry out a comprehensive and comparative study of existing UAV path-planning algorithms for both methods. Three different obstacle scenarios test the performance of each algorithm. We have compared the computational time and solution optimality, and tested each algorithm with variations in the availability of global and local obstacle information.

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