Current Status of the ASME Materials Properties Database Development

Author(s):  
Weiju Ren ◽  
Lianshan Lin

The ASME Materials Properties Database has been under development in the past few years to support the ASME Codes and Standards under the supervision of the Boiler and Pressure Vessel Code Committee on Materials. With the guidance of its Working Group on Materials Database, the project has completed the Phase I development for the Data File Warehouse that offers a depository for various files containing ASME Code Week records, materials test data from codification inquiries, and information associated with code rules development. While the database is in operation, the development has continued into Phase II to create a relational Digital Database that offers customized and relational schemas with advanced software functionalities and tools facilitating digital data processing and management. This paper discusses the current status of the project including its development management, database components and features, business operation, and future growth. Some issues and prospective resolutions for meeting the needs and requirements from Codes and Standards are also discussed.

1971 ◽  
Vol 11 ◽  
pp. 185-187
Author(s):  
J. B. Hutchings

In the past several years many, if not most, observatory microphotometers have been made or adapted to give digital output. At the same time, astronomers have been faced with the task of specifying exactly all the folk lore and experience necessary to reduce microphotometer output, so that the task can be performed by a computer. In addition to the speed and accuracy gains therefore, we have also been obliged to separate the subjective from the objective in this processing, and this may be the most important improvement of all.Knowing that many other observatories have developed similar programming systems, this paper presumably does not contain much that is startlingly new, but it is hoped that it may promote the exchange of ideas desirable to overcome common difficulties and avoid duplication (or multiplication) of effort.


Author(s):  
H. Yokoyama ◽  
H. Chikatsu

Recently, laser scanning has been receiving greater attention as a useful tool for real-time 3D data acquisition, and various applications such as city modelling, DTM generation and 3D modelling of cultural heritage sites have been proposed. And, former digital data processing were demanded in the past digital archive techniques for cultural heritage sites. However, robust filtering method for distinguishing on- and off-terrain points by terrestrial laser scanner still have many issues. In the past investigation, former digital data processing using air-bone laser scanner were reported. Though, efficient tree removal methods from terrain points for the cultural heritage are not considered. In this paper, authors describe a new robust filtering method for cultural heritage using terrestrial laser scanner with "the echo digital processing technology" as latest data processing techniques of terrestrial laser scanner.


2003 ◽  
Vol 1 (1) ◽  
pp. 87-90 ◽  
Author(s):  
Chris Garvey

Asthma rates in the US have risen during the past 25 years, as have asthma-related morbidity and healthcare costs. Professional organizations involved in asthma care have identified the need to assure that an advanced level of asthma knowledge and skill is available to patients with asthma, their families, and insurers. This need led to development of the certification for asthma educators. The Certified Asthma Educator (AE-C) must meet specific clinical criteria and pass a standardized examination designed to evaluate knowledge and skill for providing competent asthma education and coordination. The development and current status of the Certified Asthma Educator examination process and content are discussed, as are goals of the certification


1995 ◽  
Vol 32 (9-10) ◽  
pp. 267-272 ◽  
Author(s):  
A. Angelakis ◽  
E. Diamadopoulos

The basic aim of this paper is to present the existing conditions and problems of water resources management in Greece. Water demand has increased tremendously over the past 30 years. Despite adequate precipitation, water imbalance is often experienced, due to temporal and regional variations of the precipitation, the increased water demand during the summer months and the difficulty of transporting water due to the mountainous terrain. Integration of reclaimed wastewater originating from the wastewater treatment plant effluents into the water resources management is proposed. This plan exhibits the potential for reducing the pollution loads entering sea or inland waters, while at the same time providing water for irrigation.


2020 ◽  
Vol 15 ◽  
Author(s):  
Geeta Aggarwal ◽  
Manju Nagpal ◽  
Ameya Sharma ◽  
Vivek Puri ◽  
Gitika Arora Dhingra

Background: Biopharmaceuticals such as Biologic medicinal products have been in clinical use over the past three decades and have benefited towards the therapy of degenerative and critical metabolic diseases. It is forecasted that market of biologics will be going to increase at a rate of 20% per year, and by 2025, more than ˃ 50% of new drug approvals may be biological products. The increasing utilization of the biologics necessitates for cost control, especially for innovators products that have enjoyed a lengthy period of exclusive use. As the first wave of biopharmaceuticals is expired or set to expire, it has led to various opportunities for the expansion of bio-similars i.e. copied versions of original biologics with same biologic activity. Development of biosimilars is expected to promote market competition, meet worldwide demand, sustain the healthcare systems and maintain the incentives for innovation. Methods: Appraisal of published articles from peer reviewed journals, PubMed literature, latest news and guidelines from European Medicine Agency, US Food Drug Administration (FDA) and India are used to identify data for review. Results: Main insight into the quality requirements concerning biologics, current status of regulation of biosimilars and upcoming challenges lying ahead for the upgrading of marketing authorization of bio-similars has been incorporated. Compiled literature on therapeutic status, regulatory guidelines and the emerging trends and opportunities of biosimilars has been thoroughly stated. Conclusion: Updates on biosimilars will support to investigate the possible impact of bio-similars on healthcare market.


2020 ◽  
Vol 19 ◽  
pp. 153473542095944
Author(s):  
Jing Guo ◽  
Lixia Pei ◽  
Lu Chen ◽  
Hao Chen ◽  
Dongmei Gu ◽  
...  

Purpose: Acupuncture has been used for managing cancer-related symptoms. However, there are still few studies concerning the overall trends in acupuncture therapy on cancer based on bibliometric analysis. This study aims to demonstrate the current status and trends in this field over the past 2 decades. Methods: Articles were retrieved from the Web of Science from 2000 to 2019. CiteSpace was used for co-authorship network of countries/institutions, dual-map analysis, and detecting the keywords with citation bursts. VOSviewer was used to construct networks based on co-authorship and co-citation analysis of authors, and co-occurrence of keywords. Results: A total of 927 articles and reviews were included in the final analysis. The number of publications has steadily increased with some fluctuations among years. The country and institution contributing most to this field are the USA and Memorial Sloan Kettering Cancer Center. Mao JJ was the most productive author and Molassiotis A ranked first in the cited authors. The co-occurrence analysis revealed 5 clusters (including “clinical trials,” “clinical studies on chemotherapy/radiation-induced symptoms,” “CAM therapy for cancer,” “clinical studies on vasomotor symptoms,” and “systematic reviews”). Most recent keyword bursts were “neuropathic pain,” “arthralgia,” “prevention,” “supportive care,” and “integrative medicine”. Conclusions: The annual publication output would increase rapidly in the next decade, which shows a promising future in this research field. Future research hotspots would focus on the role of acupuncture in neuropathic pain, arthralgia, prevention, supportive care, and integrative medicine.


Author(s):  
Yu Yao ◽  
Heng Liang ◽  
Xin Fang ◽  
Shengnan Zhang ◽  
Zikang Xing ◽  
...  

AbstractIndoleamine 2,3-dioxygenase 1 (IDO1), a monomeric heme-containing enzyme, catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan metabolism, which plays an important role in immunity and neuronal function. Its implication in different pathophysiologic processes including cancer and neurodegenerative diseases has inspired the development of IDO1 inhibitors in the past decades. However, the negative results of the phase III clinical trial of the would-be first-in-class IDO1 inhibitor (epacadostat) in combination with an anti-PD1 antibody (pembrolizumab) in patients with advanced malignant melanoma call for a better understanding of the role of IDO1 inhibition. In this review, the current status of the clinical development of IDO1 inhibitors will be introduced and the key pre-clinical and clinical data of epacadostat will be summarized. Moreover, based on the cautionary notes obtained from the clinical readout of epacadostat, strategies for the identification of reliable predictive biomarkers and pharmacodynamic markers as well as for the selection of the tumor types to be treated with IDO1inhibitors will be discussed.


2021 ◽  
Vol 11 (11) ◽  
pp. 5039
Author(s):  
Yosoon Choi ◽  
Yeanjae Kim

A smart helmet is a wearable device that has attracted attention in various fields, especially in applied sciences, where extensive studies have been conducted in the past decade. In this study, the current status and trends of smart helmet research were systematically reviewed. Five research questions were set to investigate the research status of smart helmets according to the year and application field, as well as the trend of smart helmet development in terms of types of sensors, microcontrollers, and wireless communication technology. A total of 103 academic research articles published in the past 11 years (2009–2020) were analyzed to address the research questions. The results showed that the number of smart helmet applications reported in literature has been increasing rapidly since 2018. The applications have focused mostly on ensuring the safety of motorcyclists. A single-board-based modular concept unit, such as the Arduino board, and sensor for monitoring human health have been used the most for developing smart helmets. Approximately 85% of smart helmets have been developed to date using wireless communication technology to transmit data obtained from smart helmets to other smart devices or cloud servers.


2014 ◽  
Author(s):  
C. Tenzer ◽  
A. Argan ◽  
A. Cros ◽  
Y. Favre ◽  
M. Gschwender ◽  
...  

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