Knee Surgery Is Associated With Greater Odds of Knee Osteoarthritis Diagnosis

2019 ◽  
Vol 28 (7) ◽  
pp. 716-723
Author(s):  
Abbey C. Thomas ◽  
Janet E. Simon ◽  
Rachel Evans ◽  
Michael J. Turner ◽  
Luzita I. Vela ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Knee Injury ◽  
Online Survey ◽  
Disease Onset ◽  
Knee Surgery ◽  
Lower Extremity Injury ◽  
Odds Ratios ◽  
Cross Sectional Survey ◽  
Knee Oa ◽  
History Of

Context: Knee osteoarthritis (OA) frequently develops following knee injury/surgery. It is accepted that knee injury/surgery precipitates OA with previous studies examining this link in terms of years after injury/surgery. However, postinjury OA prevalence has not been examined by decade of life; thereby, limiting our understanding of the age at which patients are diagnosed with posttraumatic knee OA. Objective: Evaluate the association between the knee injury and/or surgical history, present age, and history of receiving a diagnosis of knee OA. Design: Cross-sectional survey. Setting: Online survey. Participants: A total of 3660 adults were recruited through ResearchMatch©. Of these, 1723 (47.1%) were included for analysis due to history of (1) knee surgery (SURG: n = 276; age = 53.8 [15.3] y; and body mass index [BMI] = 29.9 [8.0] kg/m2), (2) nonsurgical knee injury (INJ: n = 449; age = 46.0 [15.6] y; and BMI = 27.5 [6.9] kg/m2), or (3) no knee injury (CTRL: n = 998; age = 44.0 [25.2] y; and BMI = 26.9 [6.6] kg/m2). Respondents were subdivided by decade of life (20–29 through 70+). Intervention: An electronic survey regarding knee injury history, treatment, and diagnosis of knee OA. Main Outcome Measures: Binary logistic regression determined the association between knee surgical status and OA by decade of life. Participants with no histories of OA or lower-extremity injury were the referent categories. BMI was a covariate in all analyses. Results: SURG respondents were more likely to report having knee OA than CTRL for all age groups (odds ratios: 11.43–53.03; P < .001). INJ respondents aged 30 years and older were more likely to have OA than CTRL (odds ratios: 2.99–14.22; P < .04). BMI influenced associations for respondents in their 50s (P = .001) and 60s (P < .001) only. Conclusions: INJ increased the odds of reporting a physician diagnosis of knee OA in adults as young as 30 to 39 years. Importantly, SURG yielded 3 to 4 times greater odds of being diagnosed with knee OA compared with INJ in adults as young as 20 to 29 years. Delaying disease onset in these young adults is imperative to optimize the quality of life long term after surgery.

The Long-Term Impact of Osteoarthritis Following Knee Surgery in Former College Athletes

2019 ◽  
Vol 28 (1) ◽  
pp. 33-38 ◽  
Author(s):  
Janet E. Simon ◽  
Dustin R. Grooms ◽  
Carrie L. Docherty
Keyword(s):  
Knee Injury ◽  
College Athletes ◽  
Short Form ◽  
Knee Surgery ◽  
Mean Difference ◽  
Short Form 36 ◽  
Knee Oa ◽  
Quality Of Life Scale ◽  
History Of

Context: Individuals who sustain a knee surgery have been shown to have an increased likelihood to develop osteoarthritis (OA). Objective: Identify the consequences of knee surgery in a cohort of former college athletes. Design: Cross-sectional. Setting: Research laboratory. Participants: A group of 100 former Division I college athletes aged 40–65 years (60 males and 40 females) participated in the study. Interventions: All individuals self-reported whether they sustained a knee injury during college requiring surgery and if they have been diagnosed with knee OA by a medical physician post knee injury. Individuals were categorized into 3 groups: no history of knee injury requiring surgery (33 males and 24 females; 54.53 [5.95] y), history of knee surgery in college with no diagnosis of OA later in life (4 males and 6 females; 51.26 [7.29] y), and history of knee surgery in college with physician diagnosed OA later in life (23 males and 10 females; 54.21 [7.64] y). All individuals completed the knee injury and osteoarthritis outcome score (KOOS) and short form-36 version 2. Main Outcome Measures: Scores on the KOOS and short form-36 version 2. Results: A majority (76.7%) of individuals who had a knee surgery in college did develop OA. The largest mean differences were between the healthy knee and surgical knee/OA groups on the KOOS-quality of life scale (mean difference: 49.76; χ2(3) = 44.65; P < .001) and KOOS-sports scale (mean difference: 43.69; χ2(3) = 28.69; P < .001), with the surgical knee/OA group scoring worse. Conclusions: Later in life functional limitations were observed in individuals who sustained a knee injury requiring surgery and developed OA. These findings support increased efforts toward prevention of knee injuries and consideration of the long-term implication when making treatment and return to activity decisions.

scholarly journals Resilience, well-being, depression symptoms and concussion levels in equestrian athletes

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Annika McGivern ◽  
Stephen Shannon ◽  
Gavin Breslin
Keyword(s):  
Mental Health ◽  
Online Survey ◽  
Well Being ◽  
Depression Symptoms ◽  
Physical And Mental Health ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Content Type ◽  
Mental Health Support ◽  
History Of

Purpose This paper aims to conduct the first cross-sectional survey on depression, Resilience, well-being, depression symptoms and concussion levels in equestrian athletes and to assess whether past concussion rates were associated with depression, resilience and well-being. Design/methodology/approach In total, 511 participants from Canada, Republic of Ireland, UK, Australia and USA took part in an international cross-sectional, online survey evaluating concussion history, depression symptoms, resilience and well-being. Findings In total, 27.1% of athletes met clinically relevant symptoms of major depressive disorder. Significant differences were shown in the well-being and resilience scores between countries. Significant relationships were observed between reported history of concussion and both high depression scores and low well-being scores. Practical implications Findings highlight the need for mental health promotion and support in equestrian sport. Social implications Results support previous research suggesting a need for enhanced mental health support for equestrians. There is reason to believe that mental illness could still be present in riders with normal levels of resilience and well-being. Originality/value This study examined an understudied athlete group: equestrian athletes and presents important findings with implications for the physical and mental health of this population.

scholarly journals The effect of COVID-19 on medical students’ education and wellbeing: a cross-sectional survey

2021 ◽  
Author(s):  
Hassan ElHawary ◽  
Ali Salimi ◽  
Natasha Barone ◽  
Peter Alam ◽  
Stephanie Thibaudeau
Keyword(s):  
Medical Students ◽  
Online Survey ◽  
Leisure Activities ◽  
Prior History ◽  
Cross Sectional Survey ◽  
Health Habits ◽  
Cross Sectional ◽  
Canadian Medical School ◽  
History Of

Background: Canadian medical school curriculums have undergone major restructuring during the COVID-19 pandemic. This study’s goal was to assess the perceived impact of COVID-19 on medical students’ education and wellbeing.  Methods: An online survey was distributed to Canadian medical students.  Descriptive analyses and ANOVAs were used to assess changes in mental health, health habits and quality of education during the pandemic. Results: 248 medical students from 13 schools across Canada participated in this study. 74% reported a reduction in the quality of their education since COVID-19. 58% of students found online to be inferior to in-person teaching. 65% of students had more time for wellness and leisure activities, about half of the cohort felt more depressed (48%) and lonelier (52%). Student’s overall health habits worsened after the start of the pandemic (F=37.4, p < 0.001). Alcohol drinking, time spent seated, and screen time also increased since the pandemic (p < 0.001). During the pandemic, students with a prior history of depression or anxiety expressed increased depressive symptoms (66% vs. 42%, p =0.003), increased anxiety (69% vs. 41%, p < 0001), worse sleep quality (34% vs. 18%, p = 0.031), and poorer quality of life (55% vs. 65%, p = 0.024) versus those with no prior history. Conclusion: Canadian medical student’s education and wellbeing has been negatively impacted during the pandemic.

scholarly journals AB0879 DOES BODY WEIGHT INFLUENCE THE KNEE INJURY AND OSTEOARTHRITIS OUTCOME SCORE IN PERSONS WITH SYMPTOMATIC KNEE OSTEOARTHRITIS?

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1745.2-1745
Author(s):  
A. Ben Tekaya ◽  
L. Rouached ◽  
A. Slimi ◽  
J. Galalou ◽  
E. Bahlouli ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Functional Impairment ◽  
Knee Injury ◽  
Short Form ◽  
Normal Weight ◽  
Knee Oa ◽  
Outcome Score ◽  
Symptomatic Knee Osteoarthritis ◽  
Symptomatic Knee ◽  
Grade Iii

Background:Overweight is a major risk factor for the development and progression of knee osteoarthritis (OA). Weight loss for patients with knee OA has been associated with improvement in self-reported pain and function and is recommended by EULAR as part of the therapeutic management.Objectives:The aim of the study was to evaluate the relation between overweight and functional impairment in adults with knee OA.Methods:It was a prospective study conducted in a rheumatologic department over a 4 months period. Patients with symptomatic knee OA based on the ACR criteria, were included. A screening of body mass index (BMI) was carried out for all patients. It was categorized following the WHO classification into: normal (<25 kg/m2), overweight (25 to <30), obese (up to 30).Pain level was evaluated using the Visual Analogue Scale (VAS). Function was assessed by the short form of the Knee injury and Osteoarthritis Outcome Score (KOOS-PS) (KOOS-PS scores to 0 representing no difficulty and 100 representing extreme difficulty). The patients’ knee radiographies were graded according to Kellgren Lawrence criteria (KL). The patients were allocated in two groups; as grade I-II KL (Group 1) and grade III-IV KL (Group 2).Results:We included 143 patients with a mean age of 65.17± 10.7 years and 88.1% of women. Patients were from low socio-economic class in 30.8% of cases. Mean disease duration of the KOA was 5.4 years [3months-20 years] and mean BMI was 31.8±5.6kg/m2. Patients were with normal weight in 16.1%, overweight in 19.6% and obese in 64.3%.Knee OA was bilateral in 85.3% and other OA sites were associated in 37.8% of patients. Mean VAS pain of knee OA was 6.6±1.5 and KOOS-PS was 48.8±16.5/100. Concerning the radiographic damage; we found grade I-II (KL) in 22.6% and grade III-IV (KL) in 77.4%.High BMI (BMI≥25 kg/m2was not significantly associated with worse KOOS score (p=0.9), more pain (p=0.5) or an increasing severity of radiological knee osteoarthritis (p=0.14). Moreover, the level BMI was not associated with the presence of other OA sites (p=0.9) or a bilateral KOA (p=0.07).Conclusion:These data, from a subset of participants with symptomatic radiographic knee OA, demonstrate no correlation between obesity and pain, functional impairment and radiographic severity.Acknowledgments:noneDisclosure of Interests:None declared

scholarly journals Risk factors of knee osteoarthritis: A case-control study

2019 ◽  
Vol 35 (3) ◽  
Author(s):  
Nasrin Moghimi ◽  
Khaled Rahmani ◽  
Ali Delpisheh ◽  
Afshin Saidi ◽  
Namam Ali Azadi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Knee Osteoarthritis ◽  
Lower Limb ◽  
Knee Injury ◽  
Case Control Study ◽  
Case Control ◽  
Stage I ◽  
Limb Fracture ◽  
History Of ◽  
Control Study

Background and Objective: Knee osteoarthritis is one of the most common rheumatologic problems. To investigate risk factors related to the knee osteoarthritis a case-control study was performed using cases diagnosed in the Community Oriented Program for Control of Rheumatic Diseases (COPCORD) study, stage I. Methods: Using data from the 2012 COPCORD study, stage-I that was conducted in Sanandaj, northwestern of Iran, we runned a case-control study in 2014-2015. Cases were 700 knee osteoarthritis using American College of Rheumatology (ACR) criteria, frequency matched with 700 healthy controls that were randomly selected from the general population. Results: In multivariate analysis, statistical significant relation was observed between knee OA and some studied factors such as body mass index (P <0.001), lodging (living in highland vs. plain) (P <0.001), type of used toilet (regular vs. toilet) (P <0.001), history of using high-heeled shoes (>3 cm) (P = 0.005), history of knee Injury (P = 0.04), history of lower limb fracture (P = 0.02), Number of pregnancies (P <0.001) and history of pain and swelling (lasting for one months) (P = 0.04). Conclusions: Living in highland area, using regular toilet, having knee injury and lower limb fracture in the past were most significant associated factors with occurrence of knee osteoarthritis. doi: https://doi.org/10.12669/pjms.35.3.277 How to cite this:Moghimi N, Rahmani K, Delpisheh A, Saidi A, Azadi NA, Afkhamzadeh A. Risk factors of knee osteoarthritis: A case-control study. Pak J Med Sci. 2019;35(3):---------. doi: https://doi.org/10.12669/pjms.35.3.277 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Determination of Pain Phenotypes in Knee Osteoarthritis Using Latent Profile Analysis

Pain Medicine ◽  
2020 ◽  
Author(s):  
Andrew J Kittelson ◽  
Sarah J Schmiege ◽  
Katrina Maluf ◽  
Steven Z George ◽  
Jennifer E Stevens-Lapsley
Keyword(s):  
Older Adults ◽  
Knee Osteoarthritis ◽  
Pain Sensitivity ◽  
Knee Injury ◽  
Latent Profile Analysis ◽  
Profile Analysis ◽  
Healthy Older Adults ◽  
Knee Oa ◽  
Leg Strength ◽  
Group 4

Abstract Objective To identify clinical phenotypes of knee osteoarthritis (OA) using measures from the following domains: 1) multimorbidity; 2) psychological distress; 3) pain sensitivity; and 4) knee impairment or pathology. Design Data were collected from 152 people with knee OA and from 31 pain-free individuals. In participants with knee OA, latent profile analysis (LPA) was applied to the following measures: normalized knee extensor strength, Functional Comorbidity Index (FCI), Pain Catastrophizing Scale (PCS), and local (knee) pressure pain threshold. Comparisons were performed between empirically derived phenotypes from the LPA and healthy older adults on these measures. Comparisons were also made between pheonotypes on pain intensity, functional measures, use of health care, and history of knee injury. Results LPA resulted in a four-group solution. Compared with all other groups, group 1 (9% of the study population) had higher FCI scores. Group 2 (63%) had elevated pain sensitivity and quadriceps weakness relative to group 4 and healthy older adults. Group 3 (11%) had higher PCS scores than all other groups. Group 4 (17%) had greater leg strength, except relative to healthy older adults, and reduced pain sensitivity relative to all groups. Groups 1 and 3 demonstrated higher pain and worse function than other groups, and group 4 had higher rates of knee injury. Conclusion Four phenotypes of knee OA were identified using psychological factors, comorbidity status, pain sensitivity, and leg strength. Follow-up analyses supported the replicability of this phenotype structure, but future research is needed to determine its usefulness in knee OA care.

scholarly journals Association of Obesity, Parity, and History of Knee Injury with Knee Osteoarthritis in Female

2015 ◽  
Vol 2 (4) ◽  
Author(s):  
Ade Triyadi ◽  
Riardi Pramudiyo ◽  
Januarsih Iwan A. Rachman
Keyword(s):  
Knee Osteoarthritis ◽  
Knee Injury ◽  
History Of

scholarly journals New Viscoelastic Hydrogel Hymovis MO.RE. Single Intra-articular Injection for the Treatment of Knee Osteoarthritis in Sportsmen: Safety and Efficacy Study Results

2021 ◽  
Vol 12 ◽  
Author(s):  
Andrea Bernetti ◽  
Francesco Agostini ◽  
Federica Alviti ◽  
Nicola Giordan ◽  
Federica Martella ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Daily Living ◽  
Knee Injury ◽  
Therapeutic Option ◽  
Knee Oa ◽  
Study Results ◽  
Pain Symptoms ◽  
And Function ◽  
Time Point

Viscosupplementation by hyaluronic acid (HA) is recommended for non-surgical management of knee osteoarthritis (OA). This study investigated the efficacy and safety of a single i.a. (32 mg/4 ml) Hymovis MO.RE. injection, a new HA derivative hydrogel, for the treatment of adult regular sports players affected by knee OA arising from overuse injuries. Patients were prospectively enrolled if regularly practicing sports and diagnosed with Kellgren-Lawrence grade I-III OA. They received a single Hymovis MO.RE. intra-articular (i.a.) injection and were evaluated 30, 90, 180, and 360 days thereafter. The assessment involved measuring changes in knee function, pain, the activity of daily living (ADL), and quality of life (QOL) by using the Knee injury and Osteoarthritis Outcome Score (KOOS), GAIT analysis, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores for knee pain (WOMAC A) and function (WOMAC C), and a visual analogue scale (VAS) pain score. The study involved thirty-one patients, 23 women and eight men, whose median age was 49. KOOS function subscore, as well as GAIT cadence and velocity, showed a statistically significant increase at each time-point after injection (p &lt; 0.0001). WOMAC, KOOS pain, symptoms, ADL, and QOL scores also significantly improved at all control visits. No severe adverse events or treatment-related events were detected. A single Hymovis MO.RE. (32 mg/4 ml) intra-articular injection provides a rapid, lasting, and safe response in regular sports players affected by knee OA, possibly representing a viable therapeutic option for this demanding patient subgroup. Further investigations are necessary to confirm these findings.

scholarly journals Worsening of Radiographic Knee Osteoarthritis Following Medial Meniscus Root Tears and Non-Root Tears

2019 ◽  
Vol 7 (7_suppl5) ◽  
pp. 2325967119S0025
Author(s):  
Caitlin C. Chambers ◽  
John A. Lynch ◽  
Brian T. Feeley ◽  
Michael C. Nevitt
Keyword(s):  
Knee Osteoarthritis ◽  
Knee Injury ◽  
Medial Meniscus ◽  
Meniscal Tear ◽  
Activity Level ◽  
Root Tear ◽  
Index Visit ◽  
Meniscus Root ◽  
History Of ◽  
Meniscus Root Tear

Objectives: Medial meniscus root tear has an established association with knee osteoarthritis (OA), but little is known about the time course of cartilage breakdown or the severity of cartilage damage when compared to meniscal tears which spare the root. The aims of this study were to compare early progressive radiographic degenerative changes in knees with medial meniscus root tears (RT) and medial meniscus tears sparing the root (non-root tears: NRT), and identify risk factors for osteoarthritic progression among patients with RT. Methods: A convenience sample of 3,121 knees from 2,656 participants was drawn from the NIH-funded multicenter Osteoarthritis Initiative (OAI) database. All knees with medial meniscus RT or NRT seen on initial baseline MRI (prevalent) or on subsequent visit MRI (incident) were included. Demographics including sex, age, body mass index (BMI), activity level, knee injury, and knee pain were recorded at index visit (visit at which meniscal injury was first seen) and compared between prevalent RT versus NRT and incident RT versus NRT groups. Radiographic OA worsening was defined as an increase in Kellgren-Lawrence Grade (KLG) at any time from the last normal MRI 12 months before meniscal tear diagnosis (T-12, available in incident tears only) to the index visit (T0), to follow-up MRI 12 months after meniscal tear diagnosis (T+12). Additionally, characteristics of RT patients with OA worsening were compared to those who did not have progressive degenerative changes. Continuous variables were compared using a student’s t-test. Categorical data were compared using Fisher’s exact and chi-squared tests. Results: Within the OAI database, 78 medial meniscus RTs (45 prevalent, 33 incident) were identified, along with 1,030 medial meniscus NRTs (775 prevalent, 255 incident). 75% of incident RTs and 40.9% of incident NRTs (p<0.0001) demonstrated radiographic OA worsening in the 24 months studied, most often concurrent with the medial meniscus root tear, progressing between the last pre-injury MRI (T-12) and the index visit (T0) (Figure 1). As compared to incident NRT, patients with incident RT were more often female, heavier, had a higher activity level, a history of knee injury, and a higher KLG (table 1). Prevalent RT and NRT groups were similar in demographics and rates of radiographic OA worsening. Demographics of patients with incident RT that underwent radiographic OA progression versus those which did not progress were similar with no significant difference in sex, age, BMI, activity level, or history of knee injury and frequent knee pain. The OA progression knees were significantly more likely to have KLG of 0 -1 on pre-RT radiographs than the group that did not progress (66.7% versus 12.5%, p=0.01). Conclusion: For participants with incident medial meniscus tear during the 4-years of OAI, RTs were associated with significantly more progression of radiographic OA than NRTs. A majority of individuals with RTs deny a severe knee injury in the twelve months preceding MRI diagnosis the tear. Compared to incident NRTs, incident RTs were significantly more likely to occur in overweight and more active women, in knees with more severe radiographic OA, and had substantially worse radiographic outcome. Knees which demonstrated radiographic OA progression after incident RT were more likely to have a normal baseline KLG than those which did not progress, but otherwise there were no significant demographic predictors of OA worsening following RT. [Table: see text][Figure: see text]

scholarly journals What is the risk of knee osteoarthritis after a history of knee injury in young adults? A population-based cohort study

2019 ◽  
Vol 27 ◽  
pp. S262-S263 ◽  
Author(s):  
B. Snoeker ◽  
A. Turkiewicz ◽  
K. Magnusson ◽  
R. Frobell ◽  
D. Yu ◽  
...  
Keyword(s):  
Young Adults ◽  
Cohort Study ◽  
Knee Osteoarthritis ◽  
Knee Injury ◽  
Population Based ◽  
History Of
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