Aggregate piers have been widely used to increase bearing pressure and reduce settlement under structural footings. The ultimate bearing capacity of aggregate pier-reinforced ground is affected by the soil strength, replacement ratio of piles, and construction conditions. Various prediction models have been proposed to predict the ultimate bearing capacity. However, existing models have shown a broad range of bias, variation, and error, and they are at times unsuitable for practical design. In this study, multiple regression analysis was performed using field loading test results to predict the ultimate bearing capacity of ground reinforced by aggregate piers, and the number and type of the most efficient input variables were evaluated to build a robust predictive model. Accordingly, a multiple regression equation for predicting the ultimate bearing capacity was proposed, and a sensitivity analysis was conducted to identify the effect of input variables. In addition, a deep neural network was applied to estimate the ultimate bearing capacity. The optimal structure was selected on the basis of cross-validation results to prevent overtraining. Prediction errors for two approaches were evaluated and then compared with those of existing models.
Establishment of In Silico Prediction Models for CYP3A4 and CYP2B6 Induction in Human Hepatocytes by Multiple Regression Analysis Using Azole Compounds
