In VitroandIn VivoEfficacy of Amphotericin B Combined with Posaconazole against Experimental Disseminated Sporotrichosis
2015 ◽
Vol 59
(8)
◽
pp. 5018-5021
◽
Keyword(s):
ABSTRACTWe evaluated the combination of posaconazole with amphotericin Bin vitroand in a murine model of systemic infections caused bySporothrix brasiliensisandSporothrix schenckiisensu stricto.In vitrodata demonstrated a synergistic effect, and although posaconazole alone was effective against sporotrichosis, efficacy in terms of survival and burden reduction was increased with the combination. This combination might be an option against disseminated sporotrichosis, especially when itraconazole or amphotericin B at optimal doses are contraindicated.
2012 ◽
Vol 56
(5)
◽
pp. 2273-2277
◽
Keyword(s):
Keyword(s):
2018 ◽
Vol 18
(2)
◽
pp. 164-171
◽
2015 ◽
Vol 59
(5)
◽
pp. 2479-2487
◽
Keyword(s):
2012 ◽
Vol 56
(11)
◽
pp. 6044-6047
◽
2018 ◽
Vol 63
(2)
◽
pp. e00904-18
◽
Keyword(s):
Keyword(s):