Expression Turnover Profiling To Monitor the Antifungal Activities of Amphotericin B, Voriconazole, and Micafungin against Aspergillus fumigatus
2012 ◽
Vol 56
(5)
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pp. 2770-2772
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Keyword(s):
ABSTRACTEight highly expressed candidate genes were selected for mRNA profiling to monitor the transcriptome kinetics ofAspergillus fumigatusstrains exposed to antifungal drugs as potential biomarkers of live cells to assess treatment efficacy. Mycelia were treated with fungicidal drugs amphotericin B and voriconazole, as well as the fungistatic drug micafungin. Transcription was monitored at 0, 4, 8, and 24 h posttreatment. The expression turnover profile provides a possible tool to assess antifungal therapy effects.
2012 ◽
Vol 57
(3)
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pp. 1275-1282
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2015 ◽
Vol 53
(7)
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pp. 2084-2094
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2014 ◽
Vol 80
(20)
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pp. 6465-6472
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Keyword(s):
2012 ◽
Vol 56
(11)
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pp. 6044-6047
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Keyword(s):
2015 ◽
Vol 59
(11)
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pp. 7097-7099
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