Fluoroquinolone Resistance Associated with Target Mutations and Active Efflux in Oropharyngeal Colonizing Isolates of Viridans Group Streptococci
2000 ◽
Vol 44
(8)
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pp. 2197-2200
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Keyword(s):
ABSTRACT Oropharyngeal samples from 60 hospitalized patients (30 fluoroquinolone [FQ]-treated and 30 non-FQ-treated patients) and 30 untreated nonhospitalized healthy control subjects yielded 20 isolates of viridans group streptococci with reduced susceptibility to FQ, mostly from the hospitalized patients. An efflux phenotype was commonly encountered, expressed either alone or with topoisomerase mutations. Interspecies transfer of the efflux phenotype was demonstrated via transformation of Streptococcus pneumoniae R6 with DNA fromS. mitis and S. oralis.
2004 ◽
Vol 48
(9)
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pp. 3491-3497
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2005 ◽
Vol 49
(10)
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pp. 4315-4326
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2003 ◽
Vol 47
(11)
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pp. 3542-3547
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2003 ◽
Vol 47
(7)
◽
pp. 2072-2081
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2001 ◽
Vol 45
(9)
◽
pp. 2631-2634
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1977 ◽
Vol 37
(02)
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pp. 329-338
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Keyword(s):
2021 ◽
Vol 49
(3)
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pp. 030006052199296