New Mutation in ParE in a Pneumococcal In Vitro Mutant Resistant to Fluoroquinolones
2001 ◽
Vol 45
(3)
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pp. 952-955
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Keyword(s):
ABSTRACT For an in vitro mutant of Streptococcus pneumoniaeselected on moxifloxacin four- to eightfold-increased MICs of new fluoroquinolones, only a twofold-increased MIC of ciprofloxacin, and a twofold-decreased MIC of novobiocin were observed. This phenotype was conferred by two mutations: Ser81Phe in GyrA and a novel undescribed His103Tyr mutation in ParE, outside the quinolone resistance-determining region, in the putative ATP-binding site of topoisomerase IV.
2005 ◽
Vol 187
(4)
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pp. 1536-1540
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Keyword(s):
2003 ◽
Vol 185
(20)
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pp. 6137-6146
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2019 ◽
Vol 19
(11)
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pp. 914-926
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Keyword(s):
2000 ◽
Vol 44
(2)
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pp. 320-325
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1996 ◽
Vol 23
(5)
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pp. 424-427
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Keyword(s):
2002 ◽
Vol 46
(6)
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pp. 1651-1657
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Keyword(s):
2020 ◽
Keyword(s):
2013 ◽
Vol 13
(4)
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pp. 546-554
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