Mechanism of Synergistic Inhibition of Listeria monocytogenes Growth by Lactic Acid, Monolaurin, and Nisin
2008 ◽
Vol 74
(23)
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pp. 7126-7129
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Keyword(s):
ABSTRACT The combined lactic acid, monolaurin, and nisin effects on time-to-detection (optical density at 600 nm) extension were greater (P < 0.05) than any single or paired combination effect, which demonstrates a synergistic interaction among the antimicrobials. Monolaurin exposure caused C12:0 cell membrane incorporation. Lactic acid caused increased monolaurin C12:0 membrane incorporation, while nisin had no influence. We postulate that lactic acid-enhanced monolaurin C12:0 incorporation into the cell membrane increased membrane fluidity resulting in increased nisin activity.
2020 ◽
Vol 65
(No. 1)
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pp. 23-30
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2014 ◽
Vol 171
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pp. 147-153
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2001 ◽
Vol 25
(2)
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pp. 157-170
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Keyword(s):
2015 ◽
Vol 61
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pp. 27-31
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1989 ◽
Vol 52
(8)
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pp. 571-573
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Keyword(s):