scholarly journals Update on Cyclospora cayetanensis, a Food-Borne and Waterborne Parasite

2010 ◽  
Vol 23 (1) ◽  
pp. 218-234 ◽  
Author(s):  
Ynés R. Ortega ◽  
Roxana Sanchez
Keyword(s):  
Environmental Samples ◽  
Clinical Presentation ◽  
The United States ◽  
Coccidian Parasite ◽  
Emerging Pathogen ◽  
Cyclospora Cayetanensis ◽  
Diagnostic Assays ◽  
The Public ◽  
Food Borne ◽  
And Control

SUMMARY The coccidian parasite Cyclospora cayetanensis is recognized as an emerging pathogen that causes protracted diarrhea in humans. The first cases of Cyclospora infection were reported in the late 1970s and were observed among expatriates and travelers in regions where infections are endemic. Since then, Cyclospora has been considered a cause of traveler's diarrhea. Epidemiological investigations were reported and examined in areas of endemicity even before the true identity of Cyclospora was elucidated. Cyclospora was fully characterized in the early 1990s, but it was not until the 1995 Cyclospora outbreak in the United States and Canada that it caught the attention of the public and physicians. The biology, clinical presentation, epidemiology, diagnosis, treatment, and control of cyclosporiasis are reviewed, with a focus on diagnostic assays currently being used for clinical and environmental samples. Challenges and limitations in working with Cyclospora are also discussed.

Will Routine Annual Influenza Prevention and Control Systems Serve the United States Well in a Pandemic?

2009 ◽  
Vol 3 (S2) ◽  
pp. S160-S165 ◽  
Author(s):  
Jeanne S. Ringel ◽  
Melinda Moore ◽  
John Zambrano ◽  
Nicole Lurie
Keyword(s):  
Public Health ◽  
United States ◽  
Prevention And Control ◽  
The United States ◽  
Qualitative Assessment ◽  
Full Potential ◽  
Pandemic Preparedness ◽  
The Public ◽  
Influenza Prevention ◽  
And Control

ABSTRACTObjective: To assess the extent to which the systems in place for prevention and control of routine annual influenza could provide the information and experience needed to manage a pandemic.Methods: The authors conducted a qualitative assessment based on key informant interviews and the review of relevant documents.Results: Although there are a number of systems in place that would likely serve the United States well in a pandemic, much of the information and experience needed to manage a pandemic optimally is not available.Conclusions: Systems in place for routine annual influenza prevention and control are necessary but not sufficient for managing a pandemic, nor are they used to their full potential for pandemic preparedness. Pandemic preparedness can be strengthened by building more explicitly upon routine influenza activities and the public health system’s response to the unique challenges that arise each influenza season (eg, vaccine supply issues, higher than normal rates of influenza-related deaths). (Disaster Med Public Health Preparedness. 2009;3(Suppl 2):S160–S165)

21st Century Citizen Pharma: The FDA & Patient-Focused Product Development

2018 ◽  
Vol 44 (2-3) ◽  
pp. 309-327 ◽  
Author(s):  
Jordan Paradise
Keyword(s):  
Product Development ◽  
Health And Safety ◽  
The United States ◽  
The Public ◽  
United States Food ◽  
Recent Developments ◽  
States Food ◽  
And Control ◽  
Patient Advocacy Groups

Perpetual debate regarding the delicate balance between access and innovation and the protection of the public health and safety dominate discussions of the United States Food and Drug Administration (“FDA”). Established chiefly as a command and control federal administrative agency, iterative changes in legislation have shaped the FDA's activity in drug, biologic, and medical device regulation over the course of the last one hundred plus years. The most recent fundamental reframing of the agency's authority and directive presented itself in the 21st Century Cures Act, reflecting an important role for patient perspectives in the regulatory process. This Article explores recent developments in patient-focused product development efforts at the FDA and offers modest insights on the increasing role of patients, and patient advocacy groups, in agency decision-making. The Article terms this era “21st century citizen pharma.”

Posthumous control of copyright, its limitations and the public interest

2021 ◽  
Vol 8 (2) ◽  
pp. 32-62
Author(s):  
Desmond Osaretin Oriakhogba ◽  
Gloria Kanwulia Adeola-Adedipe
Keyword(s):  
United States ◽  
South Africa ◽  
Public Interest ◽  
United States Of America ◽  
The United States ◽  
Policy Options ◽  
The Public ◽  
And Control ◽  
Desk Research ◽  
Shed Light

Conducted as a desk research, this paper examines the interface between copyright and succession laws, the notion of testamentary freedom, its limitations and justification for its restriction. The paper draws on this examination to discuss the freedom of authors to dispose their copyright under testate and intestate arrangements, and posthumously control the use of their works under the Nigerian Copyright Act. Following this discussion, the paper identifies and examines the relevant provisions of the Copyright Act that can limit the capacity of authors to posthumously control the use of their works in Nigeria. The paper contends that authors’ liberty to transfer their copyright by testamentary disposition or operation of law, and control the use of their works posthumously, without public interest friendly limitations, can create an imbalance within the copyright system. This paper addresses the issues of whether public interest objectives may be achieved through the limitation in the extant Copyright Act, especially given the propensity for copyright misuse by authors in death, as well as during their lifetime, and what policy options may align the public interest with authors’ posthumous control of copyright. In resolving these questions, the paper draws on instances of copyright misuse in the United States of America (USA) and South Africa and situates them within the Nigerian context to shed light on the issues discussed.

Acute Enteric Disease Outbreaks

2019 ◽  
pp. 421-436
Author(s):  
Ian T. Williams ◽  
Laura Whitlock ◽  
Matthew E. Wise
Keyword(s):  
Public Health ◽  
Disease Outbreaks ◽  
The United States ◽  
Foodborne Illness ◽  
The Public ◽  
Enteric Diseases ◽  
Health Community ◽  
Public Health Officials ◽  
And Control ◽  
Investigation Process

Public health officials investigate outbreaks to control them, to prevent additional illnesses, and to learn how to prevent similar outbreaks in the future. The process the public health community uses to detect, investigate, and control enteric (intestinal) disease outbreaks from food, water, and other sources involves certain procedural steps. These include detecting a possible outbreak, defining and finding cases, generating hypotheses about likely sources, testing the hypotheses and evaluating evidence, finding contamination sources, controlling the outbreak, and determining when the outbreak is over. Investigating outbreaks of acute enteric diseases can be a dynamic and complex undertaking involving multiple public health and regulatory partners in different jurisdictions. This chapter provides an overview of the investigation process with an emphasis on multijurisdictional foodborne illness investigations in the United States.

Who, When, and Where?

2020 ◽  
pp. 21-34
Author(s):  
Pamela K. Keel
Keyword(s):  
Public Health ◽  
United States ◽  
Clinical Presentation ◽  
The United States ◽  
Public Health Burden ◽  
The Public ◽  
Purging Disorder ◽  
Cultural Ideals ◽  
Health Burden ◽  
Insight Into

Answering “who, when, and where?” establishes the public health burden associated with purging disorder and gives us insight into why someone develops the illness. Right now, over 2 million girls and women in the United States have purging disorder, and they are joined by another half-million boys and men. Cases of hysterical vomiting from the late 1800s resemble purging disorder in some respects, but vomiting in purging disorder is intentional and directed toward influencing weight or shape, supporting the influence of modern idealization of thinness. Finally, we see the emergence of purging to control weight and purging disorder following the introduction of Western cultural ideals into non-Western contexts. Non-Western cultures further shape the clinical presentation of purging disorder with misuse of traditional herbal emetics to produce purging.

scholarly journals Outbreak of cyclosporiasis in British Columbia associated with imported Thai basil

2004 ◽  
Vol 133 (1) ◽  
pp. 23-27 ◽  
Author(s):  
L. M. N. HOANG ◽  
M. FYFE ◽  
C. ONG ◽  
J. HARB ◽  
S. CHAMPAGNE ◽  
...  
Keyword(s):  
British Columbia ◽  
Case Control Study ◽  
The United States ◽  
Case Control ◽  
Emerging Pathogen ◽  
Industrial Countries ◽  
Underdeveloped Countries ◽  
Trace Back ◽  
And Control ◽  
Control Study

Sporadic outbreaks of cyclosporiasis, a common cause of protracted diarrhoea in underdeveloped countries, are often undetected and undiagnosed in industrial countries. In May 2001, an outbreak of Cyclospora cayetanensis gastroenteritis was identified in British Columbia, Canada, with 17 reported cases. We conducted a case-control study involving 12 out of the 17 reported and confirmed case patients. Eleven (92%) of the patients had consumed Thai basil, an essential ingredient in Vietnamese cuisine, compared to 3 out of 16 (19%) of the control patients (P=0·003). Trace-back investigations implicated Thai basil imported via the United States as the vehicle for this outbreak. This is the first documented sporadic outbreak of cyclosporiasis linked to Thai basil in Canada, and the first outbreak of cyclosporiasis identified in an ethnic immigrant population. This outbreak provides the opportunity to increase our understanding of this emerging pathogen and improve on our prevention and control for future outbreaks.

scholarly journals Canine Leishmaniosis: tools for diagnosis in veterinary practice in Colombia

2015 ◽  
pp. 4822-4842
Author(s):  
Víctor Acero P ◽  
Perla Ángel B ◽  
Esther Fonseca B ◽  
Lluís Ferrer ◽  
Xavier Roura
Keyword(s):  
Clinical Presentation ◽  
Control Strategies ◽  
Clinical Manifestations ◽  
Disease Diagnosis ◽  
Canine Leishmaniosis ◽  
Veterinary Clinic ◽  
The Public ◽  
Scientific Papers ◽  
And Control ◽  
Different Parts

ABSTRACT The objective of this article is to perform a critical analysis and guide veterinarians in the management of canine Leishmaniosis. A systematic literature review was performed between 2005 and 2014 including scientific papers which take into account experiences and reports of: pathogenesis, diagnosis, clinical presentation, treatment, vaccination, prevention and control strategies. We discuss the different aspects of VL management and aspects that should be taken into account depending on the country, after a patient is suspected or confirmed as positive, including the possibility of euthanasia. We describe the different clinical manifestations of the disease, diagnosis, signs and treatment of canine leishmaniosis. Canine leishmaniosis is present in different parts of the country, therefore it must be considered as a possible differential diagnosis in the veterinary clinic, in patients with dermatological and systemic signs that are compatible with various diseases. In Colombia, the patients diagnosed with cutaneous leishmaniasis could be treated and have a favorable prognosis, whereas in canines with diagnosis of visceral leishmaniasis euthanasia should be considered because of the public health implications.

scholarly journals The main lobbying development trends in the United States of America

2019 ◽  
pp. 156-163
Author(s):  
Anastasiia Trofymenko ◽  
Dmytro Lubinets
Keyword(s):  
United States ◽  
House Of Representatives ◽  
United States Of America ◽  
The United States ◽  
Legal Framework ◽  
The Public ◽  
Government Relations ◽  
American Model ◽  
Standards Of Conduct ◽  
And Control

The relevance of the issue of decreasing corruption in Ukraine causes the scientific interest in the study of such a political institution as lobbyism. An analysis of the global lobbying experience allows us to distinguish the lessons Ukraine can apply in this field. The article presents an analysis of the American lobbying model, since the United States was the first country to acknowledge and determine lobbying, as well as to develop the most advanced lobbying methods and technologies on the legislative level. The authors specify the main trends in the establishment and functioning of lobbying in the United States of America through studying the requirements of legislation in this field, imposed both on lobbyists and officials, considering ethical norms that lobbyists should be guided by in their work, subject-object determination of American lobbyism, and prevailing forms thereof in the state. As a result of the study carried out, it was found out that the legal framework for lobbying in the United States is based on the following: the principles of compulsory accountability and reporting of lobbyists and their clients, foreign clients, in particular; ethical standards of conduct for employees; restriction of lobbying for former civil servants; lobbying in all the branches of power; lobbying supervision and control by government agencies (these functions are entrusted to the Secretary of the Senate and Secretary of the House of Representatives) and the public, by lobbyists as well through establishing a Code of Lobbying Ethics, mediation between the client and the authorities. Keywords: lobbyism, lobbying, American model, Association of Government Relations Professionals, Code of Lobbying Ethics, lobby register.

Americans in the China Market: Economic Opportunities and Economic Nationalism, 1890s-1931

1977 ◽  
Vol 51 (3) ◽  
pp. 277-307 ◽  
Author(s):  
Michael H. Hunt
Keyword(s):  
The United States ◽  
Case Histories ◽  
Economic Nationalism ◽  
Domestic Industry ◽  
Public Rhetoric ◽  
The Public ◽  
Market Economic ◽  
China Market ◽  
Business Opportunities ◽  
And Control

Historians of various “schools” have seen quite different things in the United States’ long years of business activity in China. The “realists” as Professor Hunt calls them, deny that significant business opportunities existed for Americans and point to obstacles that the Chinese put in the way of trade; the “Wisconsin school,” he says, emphasizes the public rhetoric of officials and businessmen who saw China as an outlet for capitalist surpluses. Citing three case histories — kerosene, cigarettes, and textiles — Professor Hunt shows that generalization is dangerous; that success depended more on businessmen's own skill, resources, and control of their domestic industry than on help derived from an imperialistically minded government.

scholarly journals Yersinia enterocolitica: the charisma continues.

1997 ◽  
Vol 10 (2) ◽  
pp. 257-276 ◽  
Author(s):  
E J Bottone
Keyword(s):  
Yersinia Enterocolitica ◽  
The United States ◽  
Oral Route ◽  
Control Measures ◽  
Bacterial Strains ◽  
Food Borne ◽  
Sporadic Cases ◽  
Prevention And Control Measures ◽  
And Control

Yersinia enterocolitica, a gram-negative coccobacillus, comprises a heterogeneous group of bacterial strains recovered from animal and environmental reservoirs. The majority of human pathogenic strains are found among distinct serogroups (e.g. O:3, O:5,27, O:8, O:9) and contain both chromosome- and plasmid (60 to 75 kb)-mediated virulence factors that are absent in "avirulent" strains. While Y. enterocolitica is primarily a gastrointestinal tract pathogen, it may produce extraintestinal infections in hosts with underlying predisposing factors. Postinfection sequelae include arthritis and erythema nodosum, which are seen mainly in Europe among patients with serogroups O:3 and O:9 infection and HLA-B27 antigen. Y. enterocolitica is acquired through the oral route and is epidemiologically linked to porcine sources. Bacteremia is prominent in the setting of immunosuppression or in patients with iron overload or those being treated with desferrioxamine. metastatic foci following bacteremia are common and often involve the liver and spleen. Of particular concern is blood transfusion-related bacteremia. Evidence has accumulated substantiating the role of Y. enterocolitica as a food-borne pathogen that has caused six major outbreaks in the United States. The diagnosis of Y. enterocolitica gastroenteritis is best achieved through isolation of the bacterium on routine or selective bacteriologic media. When necessary, serogrouping, biogrouping, and assessment for plasmid-encoded virulence traits may aid in distinguishing virulent from "avirulent" strains. Epidemiologically, outside of identified food-borne outbreaks, the source (reservoir) of Y. enterocolitica in sporadic cases is speculative. Therefore, prevention and control measures are difficult to institute.

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