Deletion of a Cyclic AMP Receptor Protein Homologue Diminishes Germination and Affects Morphological Development of Streptomyces coelicolor
2004 ◽
Vol 186
(6)
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pp. 1893-1897
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ABSTRACT Open reading frame SCO3571 of Streptomyces coelicolor encodes a protein of the cyclic AMP (cAMP) receptor protein (CRP) superfamily of regulatory proteins. A mutant revealed a dramatic defect in germination, followed by growth delay and earlier sporulation. This phenotype correlates with those of an adenylate cyclase (cya) mutant that cannot synthesize cAMP. This finding suggests that S. coelicolor may use a Cya-cAMP-CRP system to trigger complex physiological processes such as morphogenesis.
1994 ◽
Vol 176
(3)
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pp. 905-912
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1991 ◽
Vol 173
(17)
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pp. 5419-5430
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1999 ◽
Vol 181
(2)
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pp. 689-694
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1998 ◽
Vol 180
(7)
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pp. 1777-1785
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2008 ◽
Vol 190
(20)
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pp. 6646-6659
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1997 ◽
Vol 179
(11)
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pp. 3458-3469
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2015 ◽
Vol 59
(5)
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pp. 2713-2719
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