Interaction of Vav with ENX-1, a putative transcriptional regulator of homeobox gene expression.
1996 ◽
Vol 16
(6)
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pp. 3066-3073
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Keyword(s):
The proto-oncogene product Vav plays a critical role in hematopoietic signal transduction. By using the yeast two-hybrid system, we identified a novel human protein, ENX-1, which interacts specifically with Vav both in vitro and in vivo. ENX-1 represents the human homolog of the Drosophila Enhancer of zeste gene, a member of the Polycomb group of genes, which are transcriptional regulators of homeobox gene expression. Interaction with ENX-1 suggests that Vav functions as an upstream element in the transcriptional regulation of homeobox genes, known to be important effectors in the hematopoietic system.
2001 ◽
Vol 276
(15)
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pp. 11980-11987
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Keyword(s):
2003 ◽
Vol 77
(1)
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pp. 769-775
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Keyword(s):
2003 ◽
Vol 185
(8)
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pp. 2393-2401
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2003 ◽
Vol 23
(19)
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pp. 6944-6957
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2001 ◽
Vol 183
(4)
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pp. 1423-1433
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Keyword(s):
2001 ◽
Vol 183
(10)
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pp. 3041-3049
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Keyword(s):
2005 ◽
Vol 79
(18)
◽
pp. 11824-11836
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Keyword(s):
Keyword(s):
Keyword(s):