Effect of Peptide Bioregulation on the State of Secretory Immunity in the Saliva of Elderly Patients with Chronic Generalized Periodontitis

2021 ◽  
Vol 11 (2) ◽  
pp. 218-222
Author(s):  
N. N. Bedelov ◽  
A. K. Iordanishvili ◽  
M. E. Malyshev ◽  
M. A. Vasiliev ◽  
K. A. Kerimhanov
Keyword(s):  
Elderly Patients ◽  
The State ◽  
Secretory Immunity

scholarly journals Blueberry Extracts Supplementation Improves Cognitive Function in Elderly Patients with Mild Cognitive Impairment (P14-013-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Yugang Jiang ◽  
Shoudan Sun
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Function ◽  
Elderly Patients ◽  
Natural Science ◽  
Intervention Study ◽  
The Elderly ◽  
The State ◽  
Control Group ◽  
Cognitive Aptitude

Abstract Objectives An intervention study was performed to determine if supplement containing blueberry extracts could improve cognitive function in the elderly patients with mild cognitive impairment (MCI). Methods Forty six MCI patients participated in the intervention study were paired based on their age, education level and initial the basic cognitive aptitude test (BCAT) scores and then randomly assigned to the intervention group (n = 23, which received 1.0 g/day of blueberry extracts) or blank control group (n = 23) . The endpoint was the improvement in cognitive function as evaluated by BCATs. All parameters were measured before and after the treatment period of 12 weeks. Results After 12 weeks of intervention, we observed significant improvement in their total BCAT score, space imagery efficiency, working memory and recognition memory of subjects in patients with blueberry extracts supplementation comparing to those in the control group (P = 0.006, 0.023, 0.000, 0.005, respectively). However the levels of inflammatory factors (IL-6 and TNF-α in serum) showed no significant changes after intervention. Conclusions The data indicated that blueberry has a beneficial effect on cognitive function of the elderly MCI patients, which might provide therapeutic potential for Alzheimer's disease. Funding Sources This work was supported by the State Key Program of National Natural Science Foundation of China and the State Key Program of National Natural Science Foundation of Tianjin. Supporting Tables, Images and/or Graphs

scholarly journals Dinamika Penerimaan Diri (Self Acceptance) Pada Lansia Penderita Diabetes Mellitus Tipe II DI Posyandu Lansia Desa Tasikhargo Jatisrono Wonogiri Tahun 2015

2017 ◽  
Vol 2 (1) ◽  
Author(s):  
Hanna Hanindyastiti ◽  
Insiyah Insiyah
Keyword(s):  
Diabetes Mellitus ◽  
Elderly Patients ◽  
Diabetes Management ◽  
Environmental Influence ◽  
The State ◽  
Diabetes Mellitus Type ◽  
Geriatric Syndrome ◽  
Type Ii ◽  
Diabetes Mellitus Type Ii ◽  
Self Acceptance

Abstract: Dynamics, Self-Acceptance, Elderly Patients, Diabetes Mellitus Type II. As getting older, an elderly suffered from many physical and mental consequences. The characteristics of geriatric syndrome most often experienced by diabetes mellitus depression, withdrawl and away from social activities. Some of them are suffering from severe and long diabetes mellitus. This research aims to describe how the dynamics of self-acceptance in elderly patients type II of Diabetes Mellitus in Posyandu Tasikhargo, Jatisrono, Wonogiri district in 2015.The research method used is qualitative method with the collection of data using in-depth interviews and Focus Group Discussion (FGD). The sample comprised 9 respondents with the inclusion criteria. According the results of the research on the results of the dynamics of self-acceptance to elderly patients with diabetes mellitus type 2, seven of the nine respondents able doing the good dynamics of research self. The good Self-acceptance backed by two. The inside factor including the state of his own altruistic, feeling confident, capable of receiving the advantages and the rest after suffering from diabetes mellitus. The outside factors are the environment and support social. The good dynamics of self- acceptance in elderly patients with type II of diabetes mellitus in posyandu Tasikhargo, Jatisrono, Wonogiri is by doing diabetes management, pray and genuinely accept the state of being experienced by patients. Social support and environmental influence self-acceptance. Lack of education is a factor make the difficult of self-acceptance, so the family support is actually useful to improve health. However, this support sometimes is perceived negatively by the patients as a restraint for themself, because they feel set up and was not released. For nurses with more emphasis on health education about diabetes mellitus that diabetics have sufficient knowledge of the conditions experienced.

scholarly journals Hospitalizations of the elderly for reasons related to human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) infection, Rondônia, Brazil, 2010-2018

2021 ◽  
Vol 33 ◽  
Author(s):  
Welliton Repiso Burgarelli ◽  
Luan Acas Serigiolli ◽  
Gabriel Pandolfo Marmentini ◽  
Luciano Teixeira Gomes ◽  
Cor Jesus Fernandes Fontes
Keyword(s):  
Human Immunodeficiency Virus ◽  
Elderly Patients ◽  
Acquired Immunodeficiency Syndrome ◽  
Hiv Transmission ◽  
The Elderly ◽  
Progressive Increase ◽  
The State ◽  
Immunodeficiency Virus ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

Introduction: For the elderly, cultural factors and social paradigms predispose to the rejection of condom use, which favors human immunodeficiency virus (HIV) transmission. The North region was the last area for the spread of HIV in Brazil. Rondônia, although with a slight decline in the HIV detection rate in recent years, is still among the states with high mortality rate due to HIV/acquired immunodeficiency syndrome (AIDS) in Brazil. Objective: To describe the demographic and clinical characteristics of the elderly patients who were hospitalized for reasons related to HIV infection in the state of Rondônia, Brazil. Methods: Descriptive study of secondary data recorded from 2010 to 2018. The cause of hospitalization was identified in the field referring to the main and secondary diagnoses of the hospitalization authorization form. Results: Between 2010 and 2018, Rondônia recorded 1,073,932 hospitalizations for any cause in the state’s public hospitals. Out of these, 183,803 (17.1%) were of elderly patients over 60 years of age and 249 (0.13%) were due to HIV/AIDS. There was a progressive increase in the number of hospitalizations during the study period, as well as a predominance of younger elderly men (67.1±6.0 years old). The mean length of hospitalizations was 21.3±21.1 days and 57 (24.1%) elderly patients died. Conclusion: Despite all the progress made in HIV prevention and treatment, the state of Rondônia still has a progressive increase in hospitalizations of elderly people for reasons related to HIV/AIDS. HIV transmission prevention strategies should be emphasized in the elderly population in the state.

scholarly journals Unconventional Care at a Convention Center: An Overview of Patient Focused Care at a COVID-19 Alternative Care Site in New Orleans

2021 ◽  
pp. 1-18
Author(s):  
Meghan Maslanka ◽  
John C. Carlson ◽  
Estaban Gershanik ◽  
Yanti Turang ◽  
Jacob Hurwitz ◽  
...  
Keyword(s):  
Elderly Patients ◽  
New Orleans ◽  
The State ◽  
Monitoring Station ◽  
Medical Monitoring ◽  
Alternative Care ◽  
Medical Needs ◽  
Convention Center ◽  
Basic Medical

ABSTRACT In March 2020, the State of Louisiana opened an alternative care site at the New Orleans Convention Center, known as the Medical Monitoring Station (MMS). The facility was designed, constructed, and staffed to serve a population with basic medical needs as they recovered from COVID-19. As the MMS prepared to open, local hospitals indicated a greater need for assistance with patients requiring a higher acuity of care and populations unable to be discharged due to infection risks. In response to this, the capabilities of the facility were altered to accommodate primarily elderly patients, with significant comorbidities, requiring extensive care. This manuscript presents the demographics of the first 250 patients seen at the MMS, and describes the most critical policies/protocols, interventions, and resources that proved successful in adjusting to effectively serve its population.

scholarly journals HIV/AIDS in the elderly: epidemiological impact and associated risk factors in the State of Piauí, Brazil

2020 ◽  
Vol 9 (8) ◽  
pp. e460985906
Author(s):  
Evaldo Hipólito de Oliveira ◽  
Roseane Mara Cardoso Lima Verde ◽  
Aldemir Branco Oliveira Filho ◽  
Leonardo Ferreira Soares ◽  
Francisco Tiago dos Santos Silva Júnior ◽  
...  
Keyword(s):  
Risk Factors ◽  
Elderly Patients ◽  
Family Income ◽  
The Elderly ◽  
The State ◽  
Behavioral Risk ◽  
Factors Associated ◽  
Associated Risk Factors ◽  
Hiv 1 ◽  
Hiv Aids

The objective of the present study was to determine the prevalence, epidemiological and socioeconomic profile and risk factors associated with HIV-1 infection in elderly patients diagnosed with HIV/AIDS in the state of Piauí, Brazil. A total of 805 individuals seen at the Central Laboratory of Public Health of Piauí were included. The subjects were classified into two groups: a group of individuals 18 to 59 years old and a group of those 60 years or older. These individuals were tested for HIV-1 infection (ELISA), which was monitored by TCD4+/CD8+ lymphocyte count (flow cytometry) and viral load quantification (branched DNA method), and for coinfections with HBV, HCV and HTLV-1/2 (ELISA and PCR). They also answered an epidemiological questionnaire on socio-demographic, epidemiological and clinical characteristics. The frequency of HIV-1 infection in elderly patients was 3.7% (30/805). The majority of patients were male (66.6%), had a primary school education level (90%), were married (40%) and had a family income of 1 to 4 times the minimum wage (63.3%). The main behavioral risk factors associated with these individuals included lack of condom use (100%) and a history of Sexual Transmitted Diseases – STI (53.3%), surgery (63.3%) or blood transfusion (40%). The elderly patients also had a higher frequency of HIV-HTLV-1/2 co-infection (13.3%). Identifying the main characteristics related to HIV infection in the elderly is important to show that these individuals are also susceptible to HIV-1 infection and must be made aware of risk behaviors.

scholarly journals FEATURES OF THE DYNAMIC OF ACUTE C-REACTIVE PROTEIN AND INDICATORS OF THE BODY’S IMMUNE SYSTEM AND THEIR RELATIONSHIP WITH THE CLINICAL PICTURE IN ELDERLY PATIENTS WITH ULCERATIVE GASTROINTESTINAL BLEEDING

2021 ◽  
pp. 41-46
Author(s):  
A. V. Chukhriienko ◽  
M. V. Trofimov
Keyword(s):  
Immune System ◽  
Elderly Patients ◽  
Gastrointestinal Bleeding ◽  
Clinical Picture ◽  
The State ◽  
C Reactive Protein ◽  
Cardiovascular Pathology ◽  
Reactive Protein ◽  
Group A ◽  
Group B

The aim. Improve the effectiveness of treatment of elderly patients with ulcerative gastrointestinal bleeding by studying the dynamics of the level of C-reactive protein (CRP) and immune system parameters, their relationship with the clinical picture. Materials and methods. 35 elderly patients in the period from 2019 to 2021 (according to the WHO classification — 61-90 years) with ulcerative gastrointestinal bleeding complicated by cardiovascular pathology. The gender distribution is as follows: men — 19 (54%), women — 16 (46%). The average age of the patients was 76.3 years. This category of patients was divided according to the methods of treatment of concomitant cardiovascular pathology: group A — patients who received therapy according to the standard scheme (n = 20), B — double (n = 15). As a control category of patients (n = 50) was selected. There are relatively healthy (donors), who were similar to the study group in terms of age, gender, and the method for determining indicators. Results. The state of local endoscopic hemostasis in group “A” was investigated: Forrest II was detected in 14 (70%) patients, Forrest III — in 6 (30%) patients; in group “B”: Forrest I — in 7 (47%) patients, Forrest II — in 8 (53%) patients. These results indicate that using of dual therapy leads to a change in the rheological properties of blood, which, in turn, leads to a decrease in the stability of local endoscopic hemostasis and an increased risk of recurrent bleeding compared with standard antihypertensive therapy (the studied groups are represented, respectively, 100% each). Conclusions. We have analyzed the C-reactive protein, interleukin-6 and interleukin-4. The main result of the study was the identification of the dynamics of markers in groups A and B. On the seventh day, normalization of these indicators was not revealed (in group B, it was especially pronounced). But the state of the latter was influenced by the therapy of concomitant pathology in patients with cardiovascular pathology. The clinical significance of immune indicators has been proven in many clinical examples and can be one of the objective criteria for assessing the patient’s condition, predicting the disease and correcting the treatment started.

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