SAT0165 Clinical and Laboratory Characteristics of Polyarteritis Nodosa (PAN) vs Other Systemic Necrotizing Vasculitis (SNV): Retrospective Study of 192 Patients in the North and Central Regions of Ukraine

2013 ◽  
Vol 72 (Suppl 3) ◽  
pp. A637.3-A637
Author(s):  
O. Iaremenko ◽  
L. Petelytska ◽  
T. Kharkevich
Keyword(s):  
Retrospective Study ◽  
Polyarteritis Nodosa ◽  
Necrotizing Vasculitis ◽  
The North ◽  
Central Regions

scholarly journals FRI0224 IDENTIFICATION OF RISK AND PROGNOSTIC FACTORS FOR POLYARTERITIS NODOSA PATIENTS WITH DIGITAL GANGRENE

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 695.2-695
Author(s):  
D. Xu ◽  
X. Tian ◽  
X. Zeng ◽  
F. Zhang ◽  
L. Zhao ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Prognostic Factors ◽  
Retrospective Study ◽  
Polyarteritis Nodosa ◽  
Lupus Erythematosus ◽  
Disease Duration ◽  
Response To Therapy ◽  
Smoking History ◽  
Systemic Lupus ◽  
Poor Outcomes

Background:Polyarteritis nodosa (PAN) is a segmental, necrotizing vascular disease that primarily impacts medium-sized muscle arteries. The estimated annual incidence of PAN is still lacking in China. Digital gangrene is an ischemic manifestation of the limb. However, the causes and the treatment methods vary from case to case, and the outcome is unpredictable. These features emphasize the need to identify measurable variables that accelerate digital gangrene development in PAN patients. However, little effort has been made to identify the clinical and laboratory factors that affect PAN patients with digital gangrene to anticipate their natural history and response to therapy.Objectives:Many patients with polyarteritis nodosa (PAN) complicated with digital gangrene have poor outcomes and related research information is limited. This study was carried out to identify the associated risk and prognostic factors.Methods:We conducted a retrospective study of 148 PAN patients admitted to Peking Union Medical College Hospital (PUMCH) from September 1986 to December 2018. The characteristics, therapeutic regimens, and outcome data for patients with and without gangrene were compared. The Kaplan–Meier method and Cox hazard regression model were used to evaluate the prognostic factors.Results:Forty-seven (31.8%) PAN patients had digital gangrene complications. The average age was 40.4±17.9 years and the average disease duration was 11 (4-27) months. The presence of digital gangrene was correlated with smoking history [odds ratio (OR), 4.27; 95% confidence interval (95% CI), 1.56-11.66] and eosinophil elevation (28.12; 10.30-76.8). Thirty-two (68.1%) gangrene patients received methylprednisolone pulse therapy and all of these patients were treated with cyclophosphamide. Nine patients suffered irreversible organ injury and two died. Disease duration ≥ 24 months and elevated serum C-reactive protein (CRP) were identified as hazardous factors for poor prognosis in patients with gangrene (P=0.003, HR=8.668, 95% CI 2.11, 35.55 andP=0.042, HR=27.062, 95% CI 1.13, 648.57, respectively).Conclusion:Smoking history and eosinophil elevation in PAN patients were more prone to digital gangrene and high serum CRP level predicted poor outcomes. PAN patients with smoking history and elevated eosinophils need to be seriously evaluated by clinicians. Furthermore, the CRP level should be efficiently controlled for good prognosis.References:[1]De Virgilio A, Greco A, Magliulo G, Gallo A, Ruoppolo G, Conte M, et al. Polyarteritis nodosa: A contemporary overview. Autoimmun Rev. 2016;15:564-70.[2]Pagnoux C, Seror R, Henegar C, Mahr A, Cohen P, Le Guern V, et al. Clinical features and outcomes in 348 patients with polyarteritis nodosa: a systematic retrospective study of patients diagnosed between 1963 and 2005 and entered into the French Vasculitis Study Group Database. Arthritis Rheum. 2010;62:616-26.[3]Xu D, You X, Wang Z, Zeng Q, Xu J, Jiang L, et al. Chinese Systemic Lupus Erythematosus Treatment and Research Group Registry VI: Effect of Cigarette Smoking on the Clinical Phenotype of Chinese Patients with Systemic Lupus Erythematosus. PLoS One. 2015;10:e0134451.Acknowledgments:NoDisclosure of Interests:Dong Xu: None declared, Xinping Tian: None declared, Xiaofeng Zeng Consultant of: MSD Pharmaceuticals, Fengchun Zhang: None declared, Lin Zhao: None declared, Shangzhu Zhang: None declared, Jiaxin Zhou: None declared, Jiu-liang Zhao: None declared, Xiaodan Kong: None declared

SPATIAL LAYOUT OF THE SOVIET UNION TIMBER PROCESSING COMPLEX: THE IDEA BEHIND THE FIRST FIVE-YEAR PLAN

2021 ◽  
Vol 7 (3) ◽  
pp. 131-154
Author(s):  
Ivan V. ZYKIN
Keyword(s):  
Soviet Union ◽  
Large Scale ◽  
Far East ◽  
Spatial Layout ◽  
Capital Investments ◽  
Wood Industry ◽  
North West ◽  
The North ◽  
The Soviet Union ◽  
Central Regions

During the years of Soviet power, principal changes took place in the country’s wood industry, including in spatial layout development. Having the large-scale crisis in the industry in the late 1980s — 2000s and the positive changes in its functioning in recent years and the development of an industry strategy, it becomes relevant to analyze the experience of planning the spatial layout of the wood industry during the period of Stalin’s modernization, particularly during the first five-year plan. The aim of the article is to analyze the reason behind spatial layout of the Soviet wood industry during the implementation of the first five-year plan. The study is based on the modernization concept. In our research we conducted mapping of the wood industry by region as well as of planned construction of the industry facilities. It was revealed that the discussion and development of an industrialization project by the Soviet Union party-state and planning agencies in the second half of the 1920s led to increased attention to the wood industry. The sector, which enterprises were concentrated mainly in the north-west, west and central regions of the country, was set the task of increasing the volume of harvesting, export of wood and production to meet the domestic needs and the export needs of wood resources and materials. Due to weak level of development of the wood industry, the scale of these tasks required restructuring of the branch, its inclusion to the centralized economic system, the direction of large capital investments to the development of new forest areas and the construction of enterprises. It was concluded that according to the first five-year plan, the priority principles for the spatial development of the wood industry were the approach of production to forests and seaports, intrasectoral and intersectoral combining. The framework of the industry was meant to strengthen and expand by including forests to the economic turnover and building new enterprises in the European North and the Urals, where the main capital investments were sent, as well as in the Vyatka region, Transcaucasia, Siberia and the Far East.

Economic Growth Potentials and Race/Ethnicity in Tennessee

2021 ◽  
pp. 1119-1142
Author(s):  
Madhuri Sharma
Keyword(s):  
Ethnic Diversity ◽  
Community Survey ◽  
Creative Class ◽  
Regression Analyses ◽  
North East ◽  
The North ◽  
Education And Health ◽  
Central Regions ◽  
Race Ethnicity ◽  
Racial Ethnic

This article establishes relationships between racial/ethnic diversity, segregation, and employment-by-industry-types in the counties of Tennessee. Using the American Community Survey and NAICS data, diversity scores, entropy indices, and location quotients for major-employment are computed for Tennessee's 95 counties. Cartographic analysis, followed by correlations, principal components and regression analyses help establish the above relationships. The north-east and west-central regions of Tennessee have concentration in primary-sectors of economy whereas counties with concentration in creative-class economy (e.g., Williamson, Davidson) have higher presence of Asians, and with greater human capital (education). Simultaneously, these are also the most segregated despite being diverse. Counties with higher diversity and higher share of African-Americans are segregated, despite having employment concentration in diverse set of industries. Enormous growth potentials exist in the sectors of education and health-care which can help Tennessee revitalize its economy.

Equine uveitis in the UK: a retrospective study (2008–2018)

2019 ◽  
Vol 186 (3) ◽  
pp. 92-92
Author(s):  
Fernando Malalana ◽  
Jo L Ireland ◽  
Gina Pinchbeck ◽  
Cathy M McGowan
Keyword(s):  
Retrospective Study ◽  
General Hospital ◽  
Medical Records ◽  
Referral Hospital ◽  
North West ◽  
The North ◽  
The World ◽  
Recurrent Case ◽  
Hospital Population ◽  
The Uk

BackgroundUveitis appears to be less prevalent in the UK compared with other parts of the world and studies characterising the disease in the UK are lacking. The objectives of this retrospective study were to describe acute and recurrent cases presenting for management of uveitis in a referral hospital on the North West of England and compare the signalment of horses presenting with uveitis with the equine hospital population during the same period.MethodsMedical records of horses presented to the referral Equine Hospital, University of Liverpool with signs of uveitis between 2008 and 2018 were reviewed and clinical details extracted.ResultsSeventy horses presented with uveitis; 33 were classified as acute and 37 as recurrent cases. Sixteen of the horses were affected bilaterally. More bilateral cases were classified as recurrent than acute (P=0.04). No differences in age or sex were noted between acute and recurrent cases, or between cases and the general hospital population. Warmbloods and Appaloosas were over-represented when compared with the general hospital population (P<0.001). Twenty-one horses (30 per cent, 95 per cent CI 20.5 to 41.4) underwent surgery for the control of the uveitis. Fourteen of the 70 horses (20.0 per cent, 95 per cent CI 12.3 to 30.8) underwent enucleation.ConclusionWhile relatively uncommon in the UK, uveitis can affect horses from a relatively young age. The disease appears to have a relatively higher frequency than expected in Warmbloods and Appaloosas. It is more likely that a recurrent case will have both eyes affected.

Polyarteritis nodosa-like necrotizing vasculitis in Fabry disease

1993 ◽  
Vol 16 (5) ◽  
pp. 901-902 ◽  
Author(s):  
C. B. Drachenberg ◽  
E. J. Schweitzer ◽  
S. T. Bartlett ◽  
M. T. Behrens ◽  
J. C. Papadimitriou
Keyword(s):  
Fabry Disease ◽  
Polyarteritis Nodosa ◽  
Necrotizing Vasculitis

Ehre, Schwerter und das Recht. Zweikämpfe im alten Island

2014 ◽  
Vol 19 (2) ◽  
Author(s):  
Sixt Wetzler
Keyword(s):  
Political System ◽  
Main Part ◽  
Source Material ◽  
Short Introduction ◽  
The North ◽  
Medieval Europe ◽  
Scientific Approach ◽  
Central Regions ◽  
History Of ◽  
Insight Into

AbstractIn medieval Europe, ritualized forms of duelling were not restricted to the continent’s central regions. The North Germanic areas had developed similar practices. The best source material for the phenomenon stems from Iceland. After a short introduction to the peculiarities of the early Icelandic political system, this article will briefly discuss the possibilities and problems of a scientific approach towards the history of Iceland’s first centuries. Then, after an outline of the dominant concepts of personal and family honour and fortune at this time, the paper’s main part will provide insight into specific Old Icelandic forms of duelling – especially the

scholarly journals Empirical Study on Ecological Niche Evaluation on Regional Construction Industry in China

2014 ◽  
Vol 8 (1) ◽  
pp. 164-170
Author(s):  
Yousong Wang ◽  
Yufan Zhang ◽  
Yang Li ◽  
Martin H. Asare ◽  
Yan Zhang
Keyword(s):  
Empirical Study ◽  
Construction Industry ◽  
Ecological Niche ◽  
Statistical Data ◽  
Evaluation Model ◽  
Chinese Government ◽  
Niche Theory ◽  
The North ◽  
Central Regions ◽  
Technology Level

The ecological system of the construction industry had been divided into three aspects, i.e.economy, scale and technology. Basing on the ecological niche theory, this paper established the evaluation model and studied on the ecologi-cal niche status about national regional construction industry in China using statistical data from 2007 to 2012. The analy-sis results show that Jiangsu, Zhejiang and Liaoning have the highest scores in the economic and the scaled niche. Tianjin, Beijing and Jiangsu’s technology niche are better. Overall, Integrated niche still has a better performance in Jiangsu, Zhe-jiang and Liaoning. The calculated values are 0.1002, 0.0696 and 0.0592 respectively. In terms of the discreteness and the diversity, the score of the scaled niche is the highest. The economic niche’s score is the second. And the lowest score is belonged to the technology niche. It is also found that the national construction industry has an unbalanced development in each area. The construction industry depends on the advantage of the economic investment and scaled advantage in the eastern coastal and the central regions. The level of the management and the technology is still low in the whole industry. Therefore, it is suggested that the Chinese government should enhance the strength of the construction investment and de-velopment in the north and west regions, ensuring the good developmental situation in the eastern and central regions. The R&D and the spreading of the technological advanced achievement should be strengthened. And the management and the technology level of the construction industry should be improved.

scholarly journals Surveillance of COVID-19 Using Geospatial Data: An Emergency Department Perspective

2021 ◽  
pp. 1-9
Author(s):  
S. Ashok ◽  
Malik Zaka Ullah ◽  
Nandakumar Vadivelu ◽  
Mohammed Tariqul Islam ◽  
Safa Nasereddin ◽  
...  
Keyword(s):  
Emergency Department ◽  
Inner City ◽  
Disease Outbreaks ◽  
Spatiotemporal Analysis ◽  
Academic Hospital ◽  
Hotspot Analysis ◽  
The North ◽  
Central Regions ◽  
Spread Of Infection ◽  
Case Data

<b><i>Background:</i></b> The outbreak of coronavirus 2019 (COVID-19) which emerged in December 2019 spread rapidly and created a public health emergency. Geospatial records of case data are needed in real time to monitor and anticipate the spread of infection. <b><i>Methods:</i></b> This study aimed to identify the emerging hotspots of COVID-19 using a geographic information system (GIS)-based approach. Data of laboratory-confirmed COVID-19 patients from March 15 to June 12, 2020, who visited the emergency department of a tertiary specialized academic hospital in Dubai were evaluated using ArcGIS Pro 2.5. Spatiotemporal analysis, including optimized hotspot analysis, was performed at the community level. <b><i>Results:</i></b> The cases were spatially concentrated mostly over the inner city of Dubai. Moreover, the optimized hotspot analysis showed statistically significant hotspots (<i>p</i> &#x3c; 0.01) in the north of Dubai. Waxing and waning hotspots were also observed in the southern and central regions of Dubai. Finally, there were nonsustaining hotspots in communities with a very low population density. <b><i>Conclusion:</i></b> This study identified hotspots of COVID-19 using geospatial analysis. It is simple and can be easily reproduced to identify disease outbreaks. In the future, more attention is needed in creating a wider geodatabase and identifying hotspots with more intense transmission intensity.

Sign in / Sign up

Export Citation Format

Share Document