scholarly journals Do the associations of body mass index and waist circumference with back pain change as people age? 32 years of follow-up in a British birth cohort

BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e039197
Author(s):  
Stella Muthuri ◽  
Rachel Cooper ◽  
Diana Kuh ◽  
Rebecca Hardy
Keyword(s):  
Body Mass Index ◽  
Back Pain ◽  
Waist Circumference ◽  
Birth Cohort ◽  
Body Mass ◽  
Smoking Status ◽  
Later Life ◽  
Birth Cohort Study ◽  
Occupational Class ◽  
Cross Sectional

ObjectivesTo investigate whether cross-sectional and longitudinal associations of body mass index (BMI) and waist circumference (WC) with back pain change with age and extend into later life.DesignBritish birth cohort study.SettingEngland, Scotland and Wales.ParticipantsUp to 3426 men and women from the MRC National Survey of Health and Development.Primary outcome measuresBack pain (sciatica, lumbago or recurring/severe backache all or most of the time) was self-reported during nurse interviews at ages 36, 43, 53 and 60–64 years and in a postal questionnaire using a body manikin at age 68.ResultsFindings from mixed-effects logistic regression models indicated that higher BMI was consistently associated with increased odds of back pain across adulthood. Sex-adjusted ORs of back pain per 1 SD increase in BMI were: 1.13 (95% CI: 1.01 to 1.26), 1.11 (95% CI: 1.00 to 1.23), 1.17 (95% CI: 1.05 to 1.30), 1.31 (95% CI: 1.15 to 1.48) and 1.08 (95% CI: 0.95 to 1.24) at ages 36, 43, 53, 60–64 and 68–69, respectively. Similar patterns of associations were observed for WC. These associations were maintained when potential confounders, including education, occupational class, height, cigarette smoking status, physical activity and symptoms of anxiety and depression were accounted for. BMI showed stronger associations than WC in models including both measures.ConclusionsThese findings demonstrate that higher BMI is a persistent risk factor for back pain across adulthood. This highlights the potential lifelong consequences on back pain of the rising prevalence of obesity within the population.

scholarly journals Maternal pre-pregnancy body mass index explains infant's weight and BMI at 14 months: results from a multi-ethnic birth cohort study

2009 ◽  
Vol 94 (8) ◽  
pp. 587-595 ◽  
Author(s):  
I Mesman ◽  
T J Roseboom ◽  
G J Bonsel ◽  
R J Gemke ◽  
M F van der Wal ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cohort Study ◽  
Birth Cohort ◽  
Body Mass ◽  
Birth Cohort Study

scholarly journals Life course body mass index and risk of knee osteoarthritis at the age of 53 years: evidence from the 1946 British birth cohort study

2011 ◽  
Vol 71 (5) ◽  
pp. 655-660 ◽  
Author(s):  
Andrew K Wills ◽  
Stephanie Black ◽  
Rachel Cooper ◽  
Russell J Coppack ◽  
Rebecca Hardy ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Knee Osteoarthritis ◽  
Birth Cohort ◽  
Body Mass ◽  
Prolonged Exposure ◽  
Birth Cohort Study ◽  
Activity Levels ◽  
Z Score ◽  
Knee Oa ◽  
High Bmi

IntroductionThe authors examined how body mass index (BMI) across life is linked to the risk of midlife knee osteoarthritis (OA), testing whether prolonged exposure to high BMI or high BMI at a particular period has the greatest influence on the risk of knee OA.MethodsA population-based British birth cohort of 3035 men and women underwent clinical examination for knee OA at age 53 years.Heights and weights were measured 10 times from 2 to 53 years. Analyses were stratified by gender and adjusted for occupation and activity levels.ResultsThe prevalence of knee OA was higher in women than in men (12.9% (n=194) vs 7.4% (n=108)). In men, the association between BMI and later knee OA was evident at 20 years (p=0.038) and remained until 53 years (OR per z-score 1.38 (95% CI 1.11 to 1.71)). In women, there was evidence for an association at 15 years (p=0.003); at 53 years, the OR was 1.89 (95% CI 1.59 to 2.24) per z-score increase in BMI. Changes in BMI from childhood in women and from adolescence in men were also positively associated with knee OA. A structured modelling approach to disentange the way in which BMI is linked to knee OA suggested that prolonged exposure to high BMI throughout adulthood carried the highest risk and that there was no additional risk conferred from adolescence once adult BMI had been accounted for.ConclusionThis study suggests that the risk of knee OA accumulates from exposure to a high BMI through adulthood.

scholarly journals The Relationship between Body Mass Index, Obesity, and LINE-1 Methylation: A Cross-Sectional Study on Women from Southern Italy

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Andrea Maugeri ◽  
Martina Barchitta ◽  
Roberta Magnano San Lio ◽  
Giuliana Favara ◽  
Claudia La Mastra ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Dna Methylation ◽  
Body Mass ◽  
Methylation Level ◽  
Molecular Mechanisms ◽  
Smoking Status ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Relationship

Uncovering the relationship between body mass index (BMI) and DNA methylation could be useful to understand molecular mechanisms underpinning the effects of obesity. Here, we presented a cross-sectional study, aiming to evaluate the association of BMI and obesity with long interspersed nuclear elements (LINE-1) methylation, among 488 women from Catania, Italy. LINE-1 methylation was assessed in leukocyte DNA by pyrosequencing. We found a negative association between BMI and LINE-1 methylation level in both the unadjusted and adjusted linear regression models. Accordingly, obese women exhibited lower LINE-1 methylation level than their normal weight counterpart. This association was confirmed after adjusting for the effect of age, educational level, employment status, marital status, parity, menopause, and smoking status. Our findings were in line with previous evidence and encouraged further research to investigate the potential role of DNA methylation markers in the management of obesity.

Investigating the Association Between Child Television Viewing and Measured Child Adiposity Outcomes in a Large Nationally Representative Sample of New Zealanders: A Cross-Sectional Study

2021 ◽  
pp. 1-9
Author(s):  
Matthew Hobbs ◽  
Stuart J.H. Biddle ◽  
Andrew P. Kingsnorth ◽  
Lukas Marek ◽  
Melanie Tomintz ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Waist Circumference ◽  
Parent Education ◽  
Body Mass ◽  
Parental Education ◽  
Task Force ◽  
Cross Sectional Study ◽  
Effect Modification ◽  
Tv Viewing ◽  
Cross Sectional

Background: This study investigates the association between television (TV) viewing and child adiposity and if parental education and child ethnicity moderate this association. Method: Cross-sectional, pooled (2013/2014–2016/2017) adult and child New Zealand Health Survey were matched resulting in 13,039 children (2–14 y) and parent dyads. Child TV viewing was estimated using self-reported time for each weekday and weekend. The height (in centimeters), weight (in kilograms), and waist circumference of parents and children were measured. Childhood body mass index and obesity were defined using the International Obesity Task Force cutoff values. Effect modification was assessed by interaction and then by stratifying regression analyses by parent education (low, moderate, and high) and child ethnicity (Asian, European/other, Māori, and Pacific). Results: Overall, watching ≥2 hours TV on average per day in the past week, relative to <2 hours TV viewing, was associated with a higher odds of obesity (adjusted odds ratio = 1.291 [1.108–1.538]), higher body mass index z score (b = 0.123 [0.061–0.187]), and higher waist circumference (b = 0.546 [0.001–1.092]). Interactions considering this association by child ethnicity and parent education revealed little evidence of effect modification. Conclusion: While TV viewing was associated with child adiposity, the authors found little support for a moderating role of parental education and child ethnicity.

scholarly journals Anthropometric Indices and Some Aspects of Physical Fitness in Croatian Adolescents by Gender

2019 ◽  
Vol 16 (14) ◽  
pp. 2582
Author(s):  
Martin Zvonar ◽  
Mario Kasović ◽  
Lovro Štefan
Keyword(s):  
Body Mass Index ◽  
Waist Circumference ◽  
Physical Fitness ◽  
Body Mass ◽  
The Body ◽  
Linear Regression Models ◽  
Anthropometric Indices ◽  
Cross Sectional ◽  
Standing Long Jump ◽  
Long Jump

Background. The main purpose of this study was to explore the body-mass index and waist circumference associated with physical fitness by gender. Methods. In this cross-sectional study, we included 1036 adolescents (55.4% girls) from eight randomly selected secondary schools within the city of Zagreb (Croatia). Body-mass index and waist circumference were objectively measured. Physical fitness included three tests: (1) 1 min sit-ups, (2) standing long jump and (3) a sit-and-reach test. Associations were calculated using linear regression models. Results. Boys had higher body-mass index and waist circumference values, compared to girls (p < 0.001). They also performed better in 1 min sit-ups and the standing long jump tests (p < 0.001), while girls obtained higher values in the sit-and-reach test (p < 0.001). In boys, body-mass index and waist circumference were associated with 1 min sit-ups and the standing long jump. In girls, waist circumference was also associated with 1 min sit-ups and the standing long jump, while body-mass index was only associated with this standing long jump. Conclusions. Our study shows that anthropometric indices have non-linear associations with physical fitness tests in a large sample of Croatian adolescents. Screening for thinness and obesity to predict the level of physical fitness should be of a great interest.

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