Fundus examination of 199 851 newborns by digital imaging in China: a multicentre cross-sectional study

2018 ◽  
Vol 102 (12) ◽  
pp. 1742-1746 ◽  
Author(s):  
He Tang ◽  
Na Li ◽  
Zhan Li ◽  
Meiju Zhang ◽  
Meirong Wei ◽  
...  
Keyword(s):  
Digital Imaging ◽  
Large Scale ◽  
Imaging System ◽  
Cross Sectional Study ◽  
Wide Field ◽  
Fundus Examination ◽  
Sectional Study ◽  
Cross Sectional ◽  
Ocular Abnormalities ◽  
Ocular Health

BackgroundThe prevalence of ocular abnormalities of newborn in China has seldom been reported. To report the implementation of digital imaging in ocular screening of all newborns in multiple centres in China and to describe the abnormal findings of fundus examination, we did the cross-sectional study.MethodsFundus examinations were performed on newborns within the 42 days after birth using a RetCam wide-field digital imaging system. Digital images of the posterior pole, superior, nasal and temporal retinal fields of each participant were taken. All newborns were from eights centres across China from January 2009 to July 2017.ResultsA total of 199 851 newborns were included in the study. We detected 18 198 (9.11%) abnormal cases. The most frequent abnormality was severe retinal haemorrhage (RH) found in 12 810 cases (6.41%). The other anomalies included familial exudative vitreoretinopathy, retinopathy of prematurity, abnormal fundus pigmentation, subconjunctival haemorrhage, choroidal coloboma, idiopathic retinal venous tortuosity, exudative changes and other anomalies with uncertain identities.ConclusionThis large-scale study of newborn fundus examination showed a relatively high prevalence of ocular abnormalities. Hundreds of neonates with rare disorders that severely impair ocular health were also detected at an early age. The long-term impact of other anomalies including RHs on the ocular system should be investigated by a perspective study. Our study suggested that fundus examination of newborns can play a beneficial role in ocular health.

scholarly journals Neonatal Eye Screening for 203 Healthy Term Newborns Using a Wide-Field Digital Retinal Imaging System

2020 ◽  
Author(s):  
Kenneth Teow Kheng Leong ◽  
Siti Nur Amira Abu Kassim ◽  
Jasvinjeet Kaur Sidhu ◽  
Zayani Zohari ◽  
Thivakar Sivalingam ◽  
...  
Keyword(s):  
Imaging System ◽  
Newborn Infants ◽  
Cross Sectional Study ◽  
Common Finding ◽  
Wide Field ◽  
Retinal Haemorrhage ◽  
Cross Sectional ◽  
Ocular Abnormalities ◽  
Lower Segment Caesarean Section ◽  
Retinal Haemorrhages

Abstract Purpose: This study aimed to determine the proportion and types of ocular abnormalities detected in healthy term newborns and also the risk factors associated with retinal haemorrhages.Method: This cross-sectional study comprised of 203 participants, all healthy term newborn infants in the Obstetrics and Gynaecology ward at Hospital Kuala Lumpur over a six months period. The examination list includes external eye examination, red reflex test, and fundus imaging using a wide-field digital retinal imaging system (Phoenix Clinical ICON Paediatric Retinal Camera) by a trained Investigator. The pathologies detected were documented. The results were compared with similar studies previously published in the literature.Results: Total ocular abnormalities were detected in 34% infants. The most common finding was retinal haemorrhage in 29.6% infants, of which 53.3% occurred bilaterally. Spontaneous vaginal delivery (SVD) remained the greatest risk factor which has nearly 3.5 times higher risk of newborns developing retinal haemorrhage compared to Lower Segment Caesarean Section (LSCS). There was a 6% increased likelihood of developing retinal haemorrhage for every 1 minute increment in the duration of 2nd stage of labour. Conclusion: Universal eye screening for all newborns using a wide-field digital imaging system is possible, safe and useful in detecting posterior segment disorders. The most common abnormality detected is retinal haemorrhage. Although most resolve spontaneously, a longitudinal study is needed to study the long term effect of retinal haemorrhages in these infants.

Large-Scale Cross-Sectional Study of the Problem Areas in Diabetes Survey among Japanese Patients with Type 2 Diabetes Mellitus

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 2393-PUB
Author(s):  
KENICHIRO TAKAHASHI ◽  
MINORI SHINODA ◽  
RIKA SAKAMOTO ◽  
JUN SUZUKI ◽  
TADASHI YAMAKAWA ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Large Scale ◽  
Japanese Patients ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Diabetes Survey

scholarly journals The Relationships Between Serum DHEA-S and AMH Levels in Infertile Women: A Retrospective Cross-Sectional Study

2021 ◽  
Vol 10 (6) ◽  
pp. 1211
Author(s):  
Li-Te Lin ◽  
Kuan-Hao Tsui
Keyword(s):  
Generalized Linear Models ◽  
Large Scale ◽  
Linear Models ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Dehydroepiandrosterone Sulphate ◽  
Sectional Study ◽  
Cross Sectional ◽  
Infertile Women ◽  
The Relationship

The relationship between serum dehydroepiandrosterone sulphate (DHEA-S) and anti-Mullerian hormone (AMH) levels has not been fully established. Therefore, we performed a large-scale cross-sectional study to investigate the association between serum DHEA-S and AMH levels. The study included a total of 2155 infertile women aged 20 to 46 years who were divided into four quartile groups (Q1 to Q4) based on serum DHEA-S levels. We found that there was a weak positive association between serum DHEA-S and AMH levels in infertile women (r = 0.190, p < 0.001). After adjusting for potential confounders, serum DHEA-S levels positively correlated with serum AMH levels in infertile women (β = 0.103, p < 0.001). Infertile women in the highest DHEA-S quartile category (Q4) showed significantly higher serum AMH levels (p < 0.001) compared with women in the lowest DHEA-S quartile category (Q1). The serum AMH levels significantly increased across increasing DHEA-S quartile categories in infertile women (p = 0.014) using generalized linear models after adjustment for potential confounders. Our data show that serum DHEA-S levels are positively associated with serum AMH levels.

A Re-Examination of Research on the Language of Black Children: The Need for a New Framework

1982 ◽  
Vol 164 (2) ◽  
pp. 157-172 ◽  
Author(s):  
Ida J. Stockman ◽  
Fay Boyd Vaughn-Cooke
Keyword(s):  
Working Class ◽  
Large Scale ◽  
Black Children ◽  
Cross Sectional Study ◽  
Linguistic Knowledge ◽  
Small Subset ◽  
Review Of The Literature ◽  
Sectional Study ◽  
Cross Sectional ◽  
New Framework

A review of the literature on the language of working-class Black children revealed that only a small subset of this research has focused on the acquisition and development of linguistic knowledge. Consequently major gaps exist in what is known about the linguistic abilities of these children. In an attempt to narrow these gaps, a team of researchers has initiated a large scale longitudinal and cross-sectional study of the acquisition of language by working-class Black children at the Center for Applied Linguistics in Washington, D. C. This paper will present a detailed description of the Center study. It will also critically evaluate existing research on the linguistic abilities of working-class Black children and its impact on language acquisition studies focusing on this population. The evaluation reveals that a new framework for analyzing the language of working-class Black children should be selected. The theory and methodology of the new framework are described.

scholarly journals Population preferences and attitudes towards COVID-19 vaccination: a cross-sectional study from Pakistan

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Muhammad Junaid Tahir ◽  
Muhammad Saqlain ◽  
Waleed Tariq ◽  
Summaiya Waheed ◽  
Steven H. S. Tan ◽  
...  
Keyword(s):  
Large Scale ◽  
Positive Attitude ◽  
Family Income ◽  
Vaccine Development ◽  
Population Level ◽  
Cross Sectional Study ◽  
Vaccine Uptake ◽  
Sectional Study ◽  
Government Officials ◽  
Cross Sectional

Abstract Background While vaccine development is itself a challenge; ensuring optimal vaccine uptake at population level can present an even more significant challenge. Therefore, this study aimed to assess the Pakistani population’s attitude and preferences towards the Coronavirus disease 2019 (COVID-19) vaccine. Method A cross-sectional study was carried out through an online self-administered questionnaire from 27 September 2020 to 11 October 2020. A total of 883 people responded to the survey. The questionnaire included the participants’ socio-demographic variables, attitudes, beliefs towards the COVID-19 vaccine and acceptance and rejection of vaccination, and reasons for them. Logistic regression analysis was used to analyze the predictors for vaccine acceptance and willingness to pay for the vaccine. Results A majority (70.8%) of respondents will accept the COVID-19vaccine if available, and 66.8% showed a positive attitude towards vaccination. Monthly family income, education level, self-diagnosis of COVID-19 or a friend, family member, or colleague are significant factors influencing the acceptance of COVID-19 vaccination. The dogma of being naturally immune to COVID-19 was a key reason for the refusal of the vaccine. Less than half (48%) of those who refuse will vaccinate themselves if government officials have made it compulsory. A third (33.9%) of participants were willing to pay up to (7 USD) 1000 Pkr (Pakistani Rupees) for the vaccine. Conclusion The population’s positive attitude should be improved by increasing awareness and eradicating false myths about vaccines through large-scale campaigns.

Implementation of telemedicine in times of SARS-CoV-2 in gynecology and obstetrics: Results of a nationwide cross-sectional study (Preprint)

2021 ◽  
Author(s):  
Stefan Hertling ◽  
Franziska Loos ◽  
Isabel Graul
Keyword(s):  
Large Scale ◽  
Cross Sectional Study ◽  
User Preferences ◽  
Technical Equipment ◽  
Sectional Study ◽  
Cross Sectional ◽  
Gynecology And Obstetrics ◽  
Training Courses ◽  
Economic Analyses

BACKGROUND In the COVID-19 pandemic, many consultations had to be cancelled, postponed or converted to a virtual format. Telemedicine in gynaecology (telegynaecology) could support gynaecologists and obstetricians. OBJECTIVE This study analyses the use and perception of telemedicine applications among gynaecologists in Germany. METHODS This prospective cross-sectional study was based on a survey of gynaecologists in Germany during the COVID-19 pandemic. Descriptive statistics were calculated and regression analyses were performed to show correlations. RESULTS The physicians expect telemedicine to be used in gynecology and obstetrics. 76. 4% (365/478) of the respondents rated their knowledge of telemedicine as insufficient. The majority of respondents (437/478, 91. 6%) said they did not currently use telemedicine, although 67. 3% (321/478) would like to do so. Obstacles to the introduction of telemedicine include the purchase of technical equipment (325/478, 68. 1%), administration (305/478, 64. 0%) and poor reimbursement (233/478, 48. 9%). Doctors surveyed would prefer telemedicine to communicate directly with other doctors (388/478, 81. 2%) rather than to communicate with patients (228/478, 47. 8%). In the treatment phases, 73. 2% (349/478) of the respondents would use telemedicine during follow-up. Half of the respondents would choose tele-culting as a specific approach to improving care (246/478, 51. 5%). CONCLUSIONS Telemedicine in gynecology finds little use but high acceptance among doctors. The absence of a structured framework is an obstacle to effective implementation. Training courses should be introduced to improve the limited knowledge in the use of telemedicine. More research in telegynecology is needed. These include large-scale randomized controlled trials, economic analyses and the exploration of user preferences.

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