scholarly journals The Relationships Between Serum DHEA-S and AMH Levels in Infertile Women: A Retrospective Cross-Sectional Study

2021 ◽  
Vol 10 (6) ◽  
pp. 1211
Author(s):  
Li-Te Lin ◽  
Kuan-Hao Tsui
Keyword(s):  
Generalized Linear Models ◽  
Large Scale ◽  
Linear Models ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Dehydroepiandrosterone Sulphate ◽  
Sectional Study ◽  
Cross Sectional ◽  
Infertile Women ◽  
The Relationship

The relationship between serum dehydroepiandrosterone sulphate (DHEA-S) and anti-Mullerian hormone (AMH) levels has not been fully established. Therefore, we performed a large-scale cross-sectional study to investigate the association between serum DHEA-S and AMH levels. The study included a total of 2155 infertile women aged 20 to 46 years who were divided into four quartile groups (Q1 to Q4) based on serum DHEA-S levels. We found that there was a weak positive association between serum DHEA-S and AMH levels in infertile women (r = 0.190, p < 0.001). After adjusting for potential confounders, serum DHEA-S levels positively correlated with serum AMH levels in infertile women (β = 0.103, p < 0.001). Infertile women in the highest DHEA-S quartile category (Q4) showed significantly higher serum AMH levels (p < 0.001) compared with women in the lowest DHEA-S quartile category (Q1). The serum AMH levels significantly increased across increasing DHEA-S quartile categories in infertile women (p = 0.014) using generalized linear models after adjustment for potential confounders. Our data show that serum DHEA-S levels are positively associated with serum AMH levels.

scholarly journals Relationship among atrial fibrillation, the CHA2DS2-VASc score and ischaemic stroke in patients with coronary artery disease: a propensity score matching study in Hebei, China

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Boqun Shi ◽  
Demin Liu ◽  
Qian Wang ◽  
Xue Geng ◽  
Qian Hou ◽  
...  
Keyword(s):  
Ischaemic Stroke ◽  
Generalized Linear Models ◽  
Linear Models ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Stroke Patients ◽  
Cross Sectional ◽  
Stroke Group ◽  
Artery Disease ◽  
The Relationship

Abstract Background Recent evidence has shown that the pathogenesis of ischaemic stroke associated with atrial fibrillation (AF) is complex and involves other factors in addition to arrhythmias. The purpose of this study was to investigate the relationship among AF, CHA2DS2-VASc score and ischaemic stroke in patients with coronary artery disease (CAD) in Hebei, China. Methods A total of 2,335 patients with CAD from September 2016 to May 2019 at the Second Hospital of Hebei Medical University were included (mean age 62.73 ± 10.35 years, range 26–92 years; 41.58% female). This was a cross-sectional study, and participants were divided into non-stroke (n = 1997) and ischaemic stroke groups (n = 338). Propensity score matching (PSM) was performed to match ischaemic stroke patients with non-stroke patients in a 1:4 ratio. The relationship among AF, the CHA2DS2-VASc score and ischaemic stroke was evaluated using univariable generalized linear models for different sex, age, body mass index (BMI), CAD and CHA2DS2-VASc score subgroups. Univariable and multivariable generalized linear models were used to evaluate the relationship between AF and ischaemic stroke in the different models. Results Compared with that in the non-stroke group, the prevalence of AF (8.81% vs. 14.20%, P = 0.002) in the ischaemic stroke group was higher. The proportion of patients with ischaemic stroke was significantly different between the AF group and the non-AF group (28.74% vs. 19.04%, P = 0.003). An increasing CHA2DS2-VASc score was associated with a gradual increase in the prevalence of AF (P for trend < 0.001). Subgroup analysis showed that the trend towards increased stroke risk in the AF group was consistent across the various subgroups. The multivariable analysis demonstrated that AF was not associated with ischaemic stroke compared with the absence of AF (OR = 1.55, 95% CI 0.94–2.56, P = 0.087). Conclusion In our cross-sectional study, after adjustment for confounding factors, there was no association between AF and ischaemic stroke. The increased risk of ischaemic stroke associated with AF was attenuated by atherosclerotic factors. Our study supports the current view that enhanced control of modifiable cardiovascular risk factors in patients with AF is essential.

Exploring the relationship of human–nature interaction and mindfulness: a cross-sectional study

2021 ◽  
Author(s):  
Pooja Sahni ◽  
Jyoti Kumar
Keyword(s):  
Mental Health Problems ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Significant Positive Association ◽  
Cross Sectional ◽  
Nature Relatedness ◽  
Relationship Of ◽  
The Relationship ◽  
Nature Experience

History is replete with examples where humans have sought refuge in nature for psychological restoration. In this cross-sectional study we explore the relationship of nature experience and mindfulness. Nature experience is assessed through “nature in the neighbourhood”, “frequency of visit” to nature-rich spaces, as well as one's inherent connection with nature described as “nature relatedness”. The study sample consisted of 334 Indian adults. The findings from this study show that frequency of visit to nature-rich spaces has a significant positive association with mindfulness. The hierarchical regression analysis suggests an interaction effect of “nature relatedness” in the association of the presence of nature rich spaces in the neighbourhood, frequency of visit as well as mindfulness. Interestingly, when childhood experiences were explored they had a significant association with “nature relatedness” and mindfulness. The evidence from this research suggests that nature experience may find its application as one of the mindfulness techniques prescribed for self-management of mental health problems.

scholarly journals Higher Pro-Inflammatory Dietary Score is Associated with Higher Hyperuricemia Risk: Results from the Case-Controlled Korean Genome and Epidemiology Study_Cardiovascular Disease Association Study

Nutrients ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1803 ◽  
Author(s):  
Hye Sun Kim ◽  
Minji Kwon ◽  
Hyun Yi Lee ◽  
Nitin Shivappa ◽  
James R. Hébert ◽  
...  
Keyword(s):  
Large Scale ◽  
Cross Sectional Study ◽  
Disease Association ◽  
Dietary Inflammatory Index ◽  
Sectional Study ◽  
Cross Sectional ◽  
Food Frequency ◽  
Inflammatory Index ◽  
The Relationship ◽  
Dietary Score

In previous studies, the elevated dietary inflammatory index (DII®) scores have been consistently associated with several chronic diseases. However, the relationship with hyperuricemia remains unknown. The aim of this study was to determine if the DII is associated with hyperuricemia risk. The study included 13,701 participants (men 5102; women 8599) in a large-scale cross-sectional study in South Korea. A validated semi-quantitative food frequency questionnaire (SQFFQ) was used to measure dietary intake, and blood samples were obtained to determine hyperuricemia. As the DII score increased, the hyperuricemia risk increased among women (OR 1.35, 95% CI 1.03–1.77, p trend = 0.02). However, no significant results were found for men. Women with lower BMI scores had higher risks of hyperuricemia with higher DII scores (OR 1.62, 95% CI 1.05–2.52, p trend = 0.03). As the DII increased, however, only women who consumed alcohol (“past or current drinkers”) had higher risks of hyperuricemia (OR 1.92, 1.22–3.02, p trend = 0.004). Among the DII components, intake of flavonoids showed a significant association with the hyperuricemia risk in women (OR 0.75, 0.59–0.96, p trend = 0.03). Our results suggest that higher intake of pro-inflammatory diet is significantly associated with higher risk of hyperuricemia among women. These results reinforce the importance of less pro-inflammatory habitual dietary patterns in lowering the risk of hyperuricemia and secondary afflictions such as cardiovascular diseases.

scholarly journals Positive association of SCD1 genetic variation and metabolic syndrome in dialysis patients in China

2020 ◽  
Vol 17 (2) ◽  
pp. 111-119
Author(s):  
Yanyan Guo ◽  
Zibo Xiong ◽  
Meiling Su ◽  
Limin Huang ◽  
Jinlan Liao ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Genetic Variation ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Renal Diseases ◽  
Sectional Study ◽  
Dialysis Patients ◽  
Cross Sectional ◽  
Relationship Of ◽  
The Relationship

Aim: Metabolic syndrome (MetS) diagnosed in the dialysis patients is increasingly reported which worsens the prognosis of the renal diseases. The relationship of SCD1 with MetS is largely unknown. The purpose of this study was to investigate the relationship between SCD1 polymorphism and MetS in dialysis patients. Methods: A cross-sectional study was conducted on 323 Chinese dialysis patients, and the correlation between the seven SNPs of SCD1 gene (rs10883465, rs2060792, rs1502593, rs522951, rs3071, rs3978768 and rs1393492) and MetS was analyzed. Results: One tag-SNP (rs1393492) has significantly associated with the prevalence of MetS. Dialysis patients with rs1393492 AA genotype of SCD1 are more prone to MetS (p = 0.021). Conclusion: This study shows that the rs1393492 variations of SCD1 gene are related with the development of MetS in Chinese dialysis patients.

Association of Serum 25-(OH)-D3 with Osteosarcopenic Obesity: A Cross-Sectional Study of Older Chinese

2020 ◽  
Author(s):  
Yanan Ma ◽  
Yuyan Liu ◽  
Shen Zhang ◽  
Lu Cao ◽  
Yu He ◽  
...  
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
Vitamin D Deficiency ◽  
Muscle Mass ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Osteosarcopenic Obesity ◽  
The Relationship

Abstract Background Limited and inconsistent epidemiological evidence for the relationship between vitamin D level and risk of osteosarcopenic obesity. We aimed to find out the relationship between serum level of 25-(OH)-D3 and osteosarcopenic obesity.Methods This study was a cross-sectional study. Residents from nine communities of the Tiexi District of Shenyang City were enrolled from May to October 2017. We included 4,506 eligible participants (1,601 men) for analyses. Participants were asked for an overnight fast. Thereafter, Blood samples were collected, and serum level of 25-(OH)-D3 was estimated using liquid chromatography–tandem mass spectrometry. We undertook logistic regression models adjusted for most known osteosarcopenic obesity risk factors. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated.Results Our study included a total of 4,506 participants (2,905 women). In multivariable-adjusted analyses, compared to the lowest tertile, a higher 25-(OH)-D3 level (OR was 0.77, 95% CI was 0.61, 0.98; and P for trend was 0.026) was inversely correlated with osteosarcopenic obesity. A positive association between vitamin D deficiency and osteosarcopenic obesity was found (OR was 1.33, 95% CI was 1.10, 1.62). Inverse relationships between serum level of 25-(OH)-D3 and low bone mass, as well as low muscle mass were found (P values for trend were 0.035 and 0.014, respectively). However, vitamin D deficiency only showed a positive correlation with low muscle mass (OR=1.26, 95 %CI: 1.07, 1.44).Conclusion An independent inverse dose-response association of serum 25-(OH)-D3 level with osteosarcopenic obesity, as well as its compositions was found. Our findings implied that serum 25-(OH)-D3 could be a good predictor of osteosarcopenic obesity in older northeastern Chinese.

scholarly journals Smartphone and Tablet Usage during COVID-19 Pandemic Confinement in Children under 48 Months in Barcelona (Spain)

Healthcare ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 96
Author(s):  
Àurea Cartanyà-Hueso ◽  
Cristina Lidón-Moyano ◽  
Pia Cassanello ◽  
Ana Díez-Izquierdo ◽  
Juan Carlos Martín-Sánchez ◽  
...  
Keyword(s):  
Generalized Linear Models ◽  
Screen Time ◽  
Linear Models ◽  
Geometric Mean ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Time Patterns ◽  
The Government ◽  
Probabilistic Sample

Background: Total lockdown due to COVID-19 pandemic might have potentially increased screen time in children. This study aims to describe the smartphone and tablets usage in children under 48 months living in Barcelona during the COVID-19 confinement. Methods: Cross-sectional study using a non-probabilistic sample of parents with children under 48 months living in Barcelona (Spain) during COVID-19 confinement (n = 313). We calculated percentages of exposure to smartphones and tablets. Moreover, for those children were exposed, we calculated unadjusted and adjusted Geometric Mean Ratios (GMR) of daily smartphones and tablets usage and their 95% confidence intervals (95% CI) trough Generalized Linear Models with Gamma family and link log. Associations were adjusted for potential confounders. Results: During COVID-19 confinement, 67.5% of children under 48 months were daily exposed to smartphones and tablets. Further, those children who were exposed during meals, as well as before going to bed, spend longer durations using them, aGMR = 2.38 (95% CI 1.73, 3.34) and aGMR = 1.95 (95% CI 1.34, 2.91) respectively. Conclusion: Two out of three children under 48 months living in Barcelona were daily exposed to smartphones and tablets during total lockdown due to COVID-19. Taking this findings into account cohort studies are needed to assess any change in the screen time patterns due to total confinement in order to allow the Government help families, particularly those more vulnerable, in a possible pandemic resurgence.

scholarly journals Telemedicine and eHealth Literacy in the Era of COVID-19: A Cross-Sectional Study in a Peripheral Clinic in Israel

2021 ◽  
Vol 18 (18) ◽  
pp. 9556
Author(s):  
Keren Dopelt ◽  
Nofar Avni ◽  
Yana Haimov-Sadikov ◽  
Iris Golan ◽  
Nadav Davidovitch
Keyword(s):  
Positive Association ◽  
Cross Sectional Study ◽  
Intervention Programs ◽  
The Internet ◽  
Sectional Study ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Ehealth Literacy ◽  
Personal Interaction ◽  
The Relationship

The COVID-19 pandemic mandating isolation, quarantine, and social distancing has accelerated and expanded the use of telemedicine. This study examines the extent of the use of telemedicine and the relationship between eHealth literacy and satisfaction with using telemedicine during the pandemic. A total of 156 participants from a clinic in a peripheral community in southern Israel completed an online questionnaire. We found that 85% knew how to use the internet for health information, but only one third felt safe using it to make health decisions. Furthermore, 93% used the internet for technical needs, such as renewing prescriptions or making a doctor’s appointment. Even lower use for telemedicine was found (38%) for consultation or treatment sessions. A positive association was found between eHealth literacy and satisfaction variables with using telemedicine (rp = 0.39, p < 0.001). Although respondents understood the benefits of telemedicine, they were not satisfied nor interested in online sessions after the epidemic’s end, preferring a meeting involving personal interaction. Young people and academics benefit more from telemedicine, thereby creating usage gaps and potentially increasing existing inequality. We recommend developing intervention programs, especially among vulnerable populations, to strengthen eHealth literacy and remove barriers causing skepticism about the use of telemedicine during and after the pandemic.

scholarly journals Association between Working Hours and Anxiety/Depression of Medical Staff during Large-Scale Epidemic Outbreak of COVID-19: A Cross-Sectional Study

2020 ◽  
Vol 17 (12) ◽  
pp. 1167-1174
Author(s):  
Qin Lang ◽  
Xiaojing Liu ◽  
Ying He ◽  
Qin Lv ◽  
Sibo Xu
Keyword(s):  
Medical Staff ◽  
Large Scale ◽  
Working Hours ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Epidemic Outbreak ◽  
Cross Sectional ◽  
Anxiety Depression ◽  
The Relationship ◽  
Psychological Mood

Objective This present study aimed to investigate the relationship between working hours and anxiety/depression mood of medical staff in China during COVID-19 epidemic.<br/>Methods The cross-sectional interview study was conducted during the period between February 14th and February 29th, 2020. A total of 291 Chinese medical professionals were recruited from 4 cities and participated in the study.<br/>Results In 291 participants, 116 (40.0%) medical staff experienced anxiety and 151 (51.8%) underwent depressed mood. In male, the level of GAD-7 and PHQ-9 scores increased with the elevation of working hours per day (WHPD) (β=0.579, p=0.003 and β=0.943; p=0.001) respectively. In female, nonlinear relationship mode was demonstrated. The levels of GAD-7 and PHQ-9 scores increased with the elevation of working hours when it was above 5 hours (β=1.432; p<0.001 and β=1.177; p<0.001), but it did not have a significant association with WHPD when it was less than 5 (p>0.05).<br/>Conclusion During the COVID-19 epidemic, we found a strong correlation between the psychological mood and WHPD. The correlation followed different modes in male and female medical workers. Enforcing an upper time limit of WHPD may help decrease the risk of pandemic-related psychological problems in medical workers.

scholarly journals The relationship between addictive use of social media and video games and symptoms of psychiatric disorders: A large-scale cross-sectional study.

2016 ◽  
Vol 30 (2) ◽  
pp. 252-262 ◽  
Author(s):  
Cecilie Schou Andreassen ◽  
Joël Billieux ◽  
Mark D. Griffiths ◽  
Daria J. Kuss ◽  
Zsolt Demetrovics ◽  
...  
Keyword(s):  
Social Media ◽  
Video Games ◽  
Psychiatric Disorders ◽  
Large Scale ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Use Of Social Media ◽  
The Relationship

Serum Testosterone Levels Are Positively Associated With Serum Anti-mullerian Hormone Levels in Infertile Women

2021 ◽  
Author(s):  
Li-Te Lin ◽  
Chia-Jung Li ◽  
Kuan-Hao Tsui
Keyword(s):  
Ovarian Reserve ◽  
Binary Logistic Regression ◽  
Serum Testosterone ◽  
Cross Sectional Study ◽  
Regression Analyses ◽  
Sectional Study ◽  
Androgen Excess ◽  
Cross Sectional ◽  
Infertile Women ◽  
The Relationship

Abstract Anti-Mullerian hormone (AMH) and testosterone (T) both play distinct roles in the early stages of folliculogenesis. However, the relationship between serum T and AMH levels is poorly understood. This study aimed to investigate the association between serum T and AMH levels in infertile women. A total of 1,935 infertile women aged 20 to 46 years were included in the cross-sectional study and divided into four quartile groups (Q1 to Q4) based on serum T levels. Compared to the subjects in the highest T quartile (Q4), those in the lowest T quartile (Q1) showed significantly lower AMH levels. After adjustment for age, body weight, body mass index and FSH, increasing T quartile categories were associated with higher AMH levels. Binary logistic regression analyses revealed that the odds for the risk of diminished ovarian reserve (DOR) were 11.44-fold higher in Q1 than in Q4 and the odds for the risk of excess ovarian reserve (EOR) were 10.41-fold higher in Q4 than in Q1. Our data show that serum T levels are positively associated with serum AMH levels and suggest that androgen insufficiency may be a potential risk factor for DOR; androgen excess may lead to EOR in infertile women.

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