scholarly journals Demographic, lifestyle and comorbid risk factors for all-cause mortality in a Danish cohort of middle-aged adults with incident asthma

BMJ Open ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. e049243
Author(s):  
Oliver Djurhuus Tupper ◽  
Zorana Jovanovic Andersen ◽  
Charlotte Suppli Ulrik
Keyword(s):  
Physical Activity ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Secondary Outcome ◽  
Long Term Study ◽  
Increased Risk ◽  
All Cause Mortality ◽  
Incident Asthma ◽  
First Time

ObjectiveWe aimed to identify factors associated with all-cause mortality in adults with incident asthma.Design and settingCross-sectional cohort study, in the metropolitan areas of Copenhagen and Aarhus, Denmark.ParticipantsAdults aged 50–64 years enrolled in the Danish Diet, Cancer, and Health cohort were followed up from baseline (1993–1997) in the National Patients Registry for first-time admissions for asthma and vital status. We defined incident asthma as at least one first-time hospital admission with asthma as the primary registered diagnosis between baseline and end of follow-up (2013) in participants without previously known asthma. Among the cohort comprising 57 053 individuals, we identified 785 adults (aged 50—64) with incident asthma, of whom 76 died during follow-up.Primary and secondary outcome measuresBaseline reported socioeconomic and lifestyle traits, and comorbidities associated with all-cause mortality.ResultsSelf-reported leisure-time physical activity was associated with a substantial reduction in risk with an HR of 0.53 (95% CI 0.33 to 0.85). Being male, single and having a diagnosis of hypertension or diabetes were associated with an increased risk of all-cause mortality with an HR of 1.83 (95% CI 1.14 to 2.38), 2.16 (95% CI 2.06 to 4.40), 2.47 (95% CI 1.54 to 3.95) and of 2.42 (95% CI 0.96 to 6.11), respectively.ConclusionsThis long-term study of adults with hospital contacts for incident asthma revealed that self-reported leisure-time physical activity is associated with an approximately 50% reduction in all-cause mortality. In contrast, both hypertension and diabetes were associated with a higher risk of mortality.

Physical Activity Among Preadolescents Modifies the Long-Term Association Between Sedentary Time Spent Using Digital Media and the Increased Risk of Being Overweight

2021 ◽  
pp. 1-8
Author(s):  
Elina Engberg ◽  
Marja H. Leppänen ◽  
Catharina Sarkkola ◽  
Heli Viljakainen
Keyword(s):  
Physical Activity ◽  
Digital Media ◽  
Leisure Time ◽  
Media Use ◽  
Leisure Time Physical Activity ◽  
Normal Weight ◽  
Web Based ◽  
Increased Risk

Background: This study aimed to examine whether sedentary digital media use in preadolescence increases the risk of being overweight 3 years later, and whether this association differs based on preadolescents’ leisure-time physical activity (LTPA) levels. Methods: The authors conducted a 3-year follow-up study among 4661 participants with a mean (SD) age of 11 (1) years at baseline and 14 (1) years at follow-up. A web-based questionnaire assessed sedentary digital media use and LTPA. The authors categorized baseline LTPA duration into 3 levels: 0 to 5 (low), 6 to 8 (moderate), and ≥9 (high) hours per week. In addition, the authors categorized adolescents as normal weight or overweight/obese at follow-up. Results: Greater amounts of sedentary digital media use at baseline associated with an increased risk of being overweight 3 years later even after adjusting for confounders. This only held for preadolescents with low baseline LTPA (OR = 1.14; 95% confidence interval, 1.05–1.24), but not among those with moderate (OR = 1.02; 0.91–1.15) or high (OR = 0.96; 0.85–1.08) LTPA. Conclusions: Preadolescent LTPA modified the long-term association between sedentary digital media use and being overweight; specifically, 6 hours per week or more of LTPA mitigated the increased risk of being overweight associated with higher amounts of digital media use.

scholarly journals The physical activity paradox in cardiovascular disease and all-cause mortality: the contemporary Copenhagen General Population Study with 104 046 adults

2021 ◽  
Vol 42 (15) ◽  
pp. 1499-1511 ◽  
Author(s):  
Andreas Holtermann ◽  
Peter Schnohr ◽  
Børge Grønne Nordestgaard ◽  
Jacob Louis Marott
Keyword(s):  
Physical Activity ◽  
Cardiovascular Disease ◽  
General Population ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Occupational Physical Activity ◽  
General Population Study ◽  
Hazard Ratios ◽  
All Cause Mortality

Abstract Aims  Leisure time physical activity associates with reduced risk of cardiovascular disease and all-cause mortality, while these relationships for occupational physical activity are unclear. We tested the hypothesis that leisure time physical activity associates with reduced major adverse cardiovascular events (MACE) and all-cause mortality risk, while occupational physical activity associates with increased risks. Methods and results  We studied 104 046 women and men aged 20–100 years in the Copenhagen General Population Study with baseline measurements in 2003–2014 and median 10-year follow-up. Both leisure and occupational physical activity were based on self-report with four response categories. We observed 7913 (7.6%) MACE and 9846 (9.5%) deaths from all causes. Compared to low leisure time physical activity, multivariable adjusted (for lifestyle, health, living conditions, and socioeconomic factors) hazard ratios for MACE were 0.86 (0.78–0.96) for moderate, 0.77 (0.69–0.86) for high, and 0.85 (0.73–0.98) for very high activity; corresponding values for higher occupational physical activity were 1.04 (0.95–1.14), 1.15 (1.04–1.28), and 1.35 (1.14–1.59), respectively. For all-cause mortality, corresponding hazard ratios for higher leisure time physical activity were 0.74 (0.68–0.81), 0.59 (0.54–0.64), and 0.60 (0.52–0.69), and for higher occupational physical activity 1.06 (0.96–1.16), 1.13 (1.01–1.27), and 1.27 (1.05–1.54), respectively. Similar results were found within strata on lifestyle, health, living conditions, and socioeconomic factors, and when excluding individuals dying within the first 5 years of follow-up. Levels of the two domains of physical activity did not interact on risk of MACE (P = 0.40) or all-cause mortality (P = 0.31). Conclusion  Higher leisure time physical activity associates with reduced MACE and all-cause mortality risk, while higher occupational physical activity associates with increased risks, independent of each other.

scholarly journals Leisure time physical activity in a 22-year follow-up among Finnish adults

2012 ◽  
Vol 9 (1) ◽  
pp. 121 ◽  
Author(s):  
Katja Borodulin ◽  
Tomi E Mäkinen ◽  
Päivi Leino-Arjas ◽  
Tuija H Tammelin ◽  
Markku Heliövaara ◽  
...  
Keyword(s):  
Physical Activity ◽  
Leisure Time ◽  
Leisure Time Physical Activity

scholarly journals Excess Body Mass and Leisure Time Physical Activity in the Incidence and Persistence of Chronic Pain

Pain Medicine ◽  
2020 ◽  
Vol 21 (11) ◽  
pp. 3094-3101
Author(s):  
Rahman Shiri ◽  
Tea Lallukka ◽  
Ossi Rahkonen ◽  
Päivi Leino-Arjas
Keyword(s):  
Physical Activity ◽  
Chronic Pain ◽  
Body Mass ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
The Body ◽  
Health Study ◽  
Highly Active ◽  
The City

Abstract Objective To estimate the effects of excess body mass and leisure time physical activity on the incidence and persistence of chronic pain. Design A prospective cohort study. Methods As a part of the Finnish Helsinki Health Study, we included three cohorts of employees of the City of Helsinki (18,562 observations) and defined incident chronic pain as having pain in any part of the body for more than three months at follow-up in participants without chronic pain at baseline (N = 13,029 observations). Persistent chronic pain was defined as having pain for more than three months at both baseline and follow-up (N = 5,533 observations). Results Overweight (adjusted odds ratio [OR] = 1.18, 95% confidence interval [CI] = 1.06–1.31) and obesity (OR = 1.65, 95% CI = 1.45–1.88) increased the incidence of chronic pain. Moreover, overweight (OR = 1.16, 95% CI = 1.02–1.32) and obesity (OR = 1.48, 95% CI = 1.26–1.74) increased the risk of persistent chronic pain. Vigorous leisure time physical activity reduced the incidence of chronic pain (OR = 0.85, 95% CI = 0.75–0.96). Physical activity did not influence the risk of persistent chronic pain. Furthermore, overweight/obesity modified the effect of leisure time physical activity on incident chronic pain. Inactive overweight or obese participants were at the highest risk of chronic pain (OR = 1.71, 95% CI = 1.40–2.09), while the OR dropped to 1.44 (95% CI = 1.19–1.75) in moderately active overweight or obese participants and to 1.20 (95% CI = 0.97–1.47) in highly active overweight or obese participants. Conclusions Obesity not only increases the risk of developing chronic pain, but also increases the risk of persistent pain, while leisure time physical activity reduces the risk of developing chronic pain.

scholarly journals Longitudinal changes in body composition and waist circumference by self-reported levels of physical activity in leisure among adolescents: the Tromsø study, Fit Futures

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Nils Abel Aars ◽  
Bjarne K. Jacobsen ◽  
Bente Morseth ◽  
Nina Emaus ◽  
Sameline Grimsgaard
Keyword(s):  
Physical Activity ◽  
Body Composition ◽  
Waist Circumference ◽  
Fat Mass ◽  
Lean Mass ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
First Year ◽  
Fat Mass Index

Abstract Background It is not clear how physical activity affects body composition in adolescents. Physical activity levels are often reduced during this period, and the relative proportion of body fat mass and lean mass undergo natural changes in growing adolescents. We aimed to examine whether self-reported physical activity in leisure time at baseline or change in activity during follow-up affect changes in four measures of body composition; body mass index (kg/m2), waist circumference, fat mass index (fat mass in kg/m2) and lean mass index (lean mass in kg/m2). Methods We used data from the Tromsø Study Fit Futures, which invited all first year students in upper secondary high school in two municipalities in northern Norway in 2010–2011. They were reexamined in 2012–2013. Longitudinal data was available for 292 boys and 354 girls. We used multiple linear regression analyses to assess whether self-reported level of physical activity in leisure time at baseline predicted changes in body composition, and analysis of covariance to assess the effects of change in level of activity during follow-up on change in body composition. All analyses were performed sex-specific, and a p-value of < 0.05 was considered statistically significant. Results There were no associations between self-reported leisure time physical activity in the first year of upper secondary high school and changes in any of the considered measure of body composition after 2 years of follow up, with the exception of waist circumference in boys (p = 0.05). In boys, change in fat mass index differed significantly between groups of activity change (p < 0.01), with boys adopting activity or remaining physically active having less increase in fat mass index than the consistently inactive. In girls, change in lean mass index differed significantly between groups of activity change (p = 0.04), with girls adopting physical activity having the highest increase. Conclusions Self-reported leisure time physical activity does not predict changes in body composition in adolescents after 2 years of follow up. Change in the level of physical activity is associated with change in fat mass index in boys and lean mass index in girls.

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