PWE-185 Beliefs About Management Of Irritable Bowel Syndrome In Primary Care: Cross-sectional Survey: Abstract PWE-185 Table 1

AimTo examine beliefs about irritable bowel syndrome (IBS) management among primary care physicians.BackgroundThere have been considerable advances in evidence synthesis concerning management of IBS in the last five years, with guidelines for its management in primary care published by the National Institute for Health and Care Excellence (NICE).MethodsThis was a cross-sectional web-based questionnaire survey of 275 primary care physicians. We emailed a link to a SurveyMonkey questionnaire, containing 18 items, to all eligible primary care physicians registered with three clinical commissioning groups in Leeds, UK. Participants were given one month to respond, with a reminder sent out after two weeks.FindingsOne-hundred and two (37.1%) primary care physicians responded. Among responders, 70% believed IBS was a diagnosis of exclusion, and >80% checked coeliac serology often or always in suspected IBS. Between >50% and >70% believed soluble fibre, antispasmodics, peppermint oil, and psychological therapies were potentially efficacious therapies. The respondents were less convinced that antidepressants or probiotics were effective. Despite perceived efficacy of psychological therapies, 80% stated these were not easily available. Levels of use of soluble fibre, antispasmodics, and peppermint oil were in the range of 40% to >50%. Most primary care physicians obtained up-to-date evidence about IBS management from NICE guidelines. Most primary care physicians still believe IBS is a diagnosis of exclusion, and many are reluctant to use antidepressants or probiotics to treat IBS. More research studies addressing diagnosis and treatment of IBS based in primary are required.

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Risks of Major Mental Disorders and Irritable Bowel Syndrome among the Offspring of Parents with Irritable Bowel Syndrome: A Nationwide Study

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18094679 ◽

2021 ◽

Vol 18 (9) ◽

pp. 4679

Author(s):

Ta-Chuan Yeh ◽

Ya-Mei Bai ◽

Shih-Jen Tsai ◽

Tzeng-Ji Chen ◽

Chih-Sung Liang ◽

...

Keyword(s):

Irritable Bowel Syndrome ◽

Mental Disorders ◽

Autism Spectrum ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Logistic Regression Models ◽

Early Implementation ◽

Increased Risk ◽

Nationally Representative ◽

Irritable Bowel

Irritable bowel syndrome (IBS) is a functional bowel disorder that is highly comorbid with mental disorders. However, few studies have examined the risk of attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), bipolar disorder, major depressive disorder (MDD), and schizophrenia in the offspring of parents with IBS. We used nationally representative cross-sectional survey data to analyze cross-generational transmission patterns of both IBS and major mental disorders. Odds ratio (OR) was calculated by using logistic regression models with adjustment for potential confounding factors. Offspring of parents with IBS were more likely to develop IBS themselves (OR = 2.41, 95% confidence interval (CI), 2.09–2.78), ADHD (OR = 1.33, 95% CI, 1.08–1.62), and MDD (OR = 1.32, 95% CI, 1.04–1.68) than the controls. Data stratification by parental sex revealed that paternal IBS increased risk of ADHD (OR = 1.34, 95% CI, 1.01–1.77) in the offspring, while maternal IBS increased the risk of MDD (OR = 1.51, 95% CI, 1.11–2.06). This is the first study to reveal parental IBS is associated with IBS, ADHD, and MDD among offspring, suggesting the necessity for early implementation of prevention strategies for at-risk children.

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Patients Suspected of Irritable Bowel Syndrome—Cross-Sectional Study Exploring the Sensitivity of Rome III Criteria in Primary Care

The American Journal of Gastroenterology ◽

10.1038/ajg.2013.15 ◽

2013 ◽

Vol 108 (6) ◽

pp. 972-980 ◽

Cited By ~ 37

Author(s):

Anne Line Engsbro ◽

Luise Mølenberg Begtrup ◽

Jens Kjeldsen ◽

Pia Veldt Larsen ◽

Ove Schaffalitzky de Muckadell ◽

...

Keyword(s):

Primary Care ◽

Irritable Bowel Syndrome ◽

Cross Sectional Study ◽

Sectional Study ◽

Rome Iii Criteria ◽

Cross Sectional ◽

Rome Iii ◽

Irritable Bowel

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Perception and Reality - A Study of Public Knowledge and Perceptions about Irritable Bowel Syndrome

Saudi Journal of Internal Medicine ◽

10.32790/sjim.2016.6.1.3 ◽

2016 ◽

Vol 6 (1) ◽

pp. 13-20

Author(s):

Yousef A. Qari

Keyword(s):

Irritable Bowel Syndrome ◽

Average Frequency ◽

Underlying Disease ◽

Public Knowledge ◽

Common Condition ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Poor Understanding ◽

Irritable Bowel ◽

Self Administered Questionnaire

Objective: This study aims to assess the publications knowledge base and attitudes toward irritable bowel syndrome. Methods: This cross-sectional survey was conducted from February 1 through May 1, 2015, at public venues in Jeddah. A self-administered questionnaire was designed to assess the participants' knowledge of irritable bowel syndrome. Questions were categorized as high- or low-impact based on the relevance of the question to explore more serious underlying disease. An independent t-test was used to compare group means, assuming normal distribution. Results: We recruited 376 participants; women accounted for 79.8% of the sample. Participants had fair knowledge about irritable bowel syndrome: the average frequency of correct answers on all 16 questions was 8.9 ± 2.0 (range, 3-14). One hundred sixty-one (42.8%) participants responded correctly to at least half of the questions that assessed knowledge of irritable bowel syndrome causes. Three hundred forty-four (91.5%) participants responded correctly to at least half of the questions that assessed knowledge of symptoms. Females were more knowledgeable on irritable bowel syndrome symptoms (p = 0.003). Respondents who had attended university were also more knowledgeable about irritable bowel syndrome symptoms (p = 0.032) and performed better on high-impact questions (4.3 ± 1.6 versus 3.8 ± 1.6 for respondents who had not attended university; p = 0.006). Conclusion: Participants had a poor understanding of the causes and complications of irritable bowel syndrome, suggesting that there is room for appropriate programs to educate the population about this common condition.

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Validation of a questionnaire for the assessment of knowledge, attitude, and practices in patients with irritable bowel syndrome

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20203597 ◽

2020 ◽

Vol 7 (9) ◽

pp. 1347

Author(s):

Sanjeev Khanna ◽

Abdul Khaliq ◽

Jaiprakash Kewlani ◽

Sachin Gupta ◽

Sanjay Kumar

Keyword(s):

Irritable Bowel Syndrome ◽

Internal Consistency ◽

Ordinal Scale ◽

Cronbach’S Alpha ◽

Cross Sectional Survey ◽

Knowledge Domain ◽

Cross Sectional ◽

Cronbach's Alpha ◽

Validated Questionnaire ◽

Irritable Bowel

Background: Irritable bowel syndrome (IBS) is a common disorder with a significant impact on the patients’ quality of life. The objective if this study was to develop and validate knowledge, attitude, and practices (KAP) questionnaire in patients with IBS.Methods: The questionnaire was developed by medical experts by a consultative process using available literature on KAP for patients with IBS. Contents of the questionnaire were validated based on content clarity and relevance using a 4-point ordinal scale. A cross-sectional survey of 100 individuals with IBS was carried out to establish internal consistency, followed by the establishment of the construct validity of the questionnaire.Results: The original KAP questionnaire included 32 items categorized under the 3 domains of knowledge (22 items), attitude (6 items), and practices (8 items). During expert validation, 4 items from knowledge domain and 1 item from attitude domain were revised. For the original questionnaire, for the individual KAP domains and the overall questionnaire, the Cronbach's alpha raw values were 0.384, 0.215, 0.548, and ‑0.028, and standardized values were 0.395, 0.368, 0.490, and 0.119, respectively. Six items from knowledge domain and 1 item from attitude domain were deleted to strengthen the internal consistency without jeopardizing the purpose of study. For the questionnaire with 29 items, Cronbach's alpha values improved to 0.603, 0.314, 0.548, and 0.483 (raw values) and 0.586, 0.350, 0.490, and 0.414 (standardized values), respectively.Conclusions: The validated questionnaire with 29 items had improved homogeneity as compared with the initial questionnaire with 36 items.

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Prevalence of organic disease at colonoscopy in patients with symptoms compatible with irritable bowel syndrome: cross-sectional survey

Scandinavian Journal of Gastroenterology ◽

10.3109/00365521.2015.1007079 ◽

2015 ◽

Vol 50 (7) ◽

pp. 816-823 ◽

Cited By ~ 33

Author(s):

Purav Patel ◽

Premysl Bercik ◽

David G Morgan ◽

Carolina Bolino ◽

Maria Ines Pintos-Sanchez ◽

...

Keyword(s):

Irritable Bowel Syndrome ◽

Organic Disease ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Irritable Bowel

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Blastocystis sp. Carriage and Irritable Bowel Syndrome: Is the Association Already Established?

Biology ◽

10.3390/biology10040340 ◽

2021 ◽

Vol 10 (4) ◽

pp. 340

Author(s):

Fernando Salvador ◽

Beatriz Lobo ◽

Lidia Goterris ◽

Carmen Alonso-Cotoner ◽

Javier Santos ◽

...

Keyword(s):

Irritable Bowel Syndrome ◽

Microscopic Examination ◽

Parasitic Infection ◽

Diagnostic Technique ◽

Control Group ◽

Cross Sectional ◽

Significant Difference ◽

Blastocystis Sp ◽

Irritable Bowel ◽

Asymptomatic Subjects

Background: The aim of the present study is to describe the occurrence of Blastocystis sp. detection among asymptomatic subjects and patients with irritable bowel syndrome in order to evaluate the potential association between irritable bowel syndrome and the parasitic infection. Methods: Cross-sectional study where adult patients with irritable bowel syndrome diagnosed according to Rome IV criteria were included. A control group was formed by asymptomatic subjects older than 18 years. Exclusion criteria were: immunosuppressive condition or having received any drug with demonstrated activity against Blastocystis sp. within the last 6 months before study inclusion. Epidemiological and clinical information was collected from all included participants. Two stool samples were obtained from all participants: one sample for microscopic examination and one sample for Blastocystis sp. PCR detection. Blastocystis sp. infection was defined by the positivity of any of the diagnostic techniques. Results: Seventy-two participants were included (36 asymptomatic subjects and 36 patients with irritable bowel syndrome). Thirty-five (48.6%) were men, and median age of participants was 34 (IQR 29–49) years. The overall rate of Blastocystis sp. carriage was 27.8% (20/72). The prevalence assessed through microscopic examination was 22.2% (16/72), while the prevalence measured by PCR was 15.3% (11/72). When comparing the presence of Blastocystis sp. between asymptomatic subjects and IBS patients, we did not find any statistically significant difference (36.1% vs. 19.4% respectively, p = 0.114). Conclusions: regarding the occurrence of Blastocystis sp., no differences were found between asymptomatic participants and patients with irritable bowel disease irrespective of the diagnostic technique performed.

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Prepared and highly committed despite the risk of COVID-19 infection: a cross-sectional survey of primary care physicians’ concerns and coping strategies in Singapore

BMC Family Practice ◽

10.1186/s12875-021-01370-7 ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Jerrald Lau ◽

David Hsien-Yung Tan ◽

Gretel Jianlin Wong ◽

Yii-Jen Lew ◽

Ying-Xian Chua ◽

...

Keyword(s):

Primary Care ◽

Coping Strategies ◽

Stress Management ◽

Primary Care Physicians ◽

Well Being ◽

Pandemic Preparedness ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Accessible Information ◽

And Coping

Abstract Background Primary care physicians (PCPs) are first points-of-contact between suspected cases and the healthcare system in the current COVID-19 pandemic. This study examines PCPs’ concerns, impact on personal lives and work, and level of pandemic preparedness in the context of COVID-19 in Singapore. We also examine factors and coping strategies that PCPs have used to manage stress during the outbreak. Methods Two hundred and sixteen PCPs actively practicing in either a public or private clinic were cluster sampled via email invitation from three primary care organizations in Singapore from 6th to 29th March 2020. Participants completed a cross-sectional online questionnaire consisting of items on work- and non-work-related concerns, impact on personal and work life, perceived pandemic preparedness, stress-reduction factors, and personal coping strategies related to COVID-19. Results A total of 158 questionnaires were usable for analyses. PCPs perceived themselves to be at high risk of COVID-19 infection (89.9%), and a source of risk (74.7%) and concern (71.5%) to loved ones. PCPs reported acceptance of these risks (91.1%) and the need to care for COVID-19 patients (85.4%). Overall perceived pandemic preparedness was extremely high (75.9 to 89.9%). PCPs prioritized availability of personal protective equipment, strict infection prevention guidelines, accessible information about COVID-19, and well-being of their colleagues and family as the most effective stress management factors. Conclusions PCPs continue to serve willingly on the frontlines of this pandemic despite the high perception of risk to themselves and loved ones. Healthcare organizations should continue to support PCPs by managing both their psychosocial (e.g. stress management) and professional (e.g. pandemic preparedness) needs.

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Altered Gut Microbiota in Irritable Bowel Syndrome and Its Association with Food Components

Journal of Personalized Medicine ◽

10.3390/jpm11010035 ◽

2021 ◽

Vol 11 (1) ◽

pp. 35

Author(s):

Zahra A. Barandouzi ◽

Joochul Lee ◽

Kendra Maas ◽

Angela R. Starkweather ◽

Xiaomei S. Cong

Keyword(s):

Irritable Bowel Syndrome ◽

Gut Microbiota ◽

Alpha Diversity ◽

Diversity Indices ◽

Cross Sectional Study ◽

Caffeine Intake ◽

Caffeine Consumption ◽

Cross Sectional ◽

Food Components ◽

Irritable Bowel

The interplay between diet and gut microbiota has gained interest as a potential contributor in pathophysiology of irritable bowel syndrome (IBS). The purpose of this study was to compare food components and gut microbiota patterns between IBS patients and healthy controls (HC) as well as to explore the associations of food components and microbiota profiles. A cross-sectional study was conducted with 80 young adults with IBS and 21 HC recruited. The food frequency questionnaire was used to measure food components. Fecal samples were collected and profiled by 16S rRNA Illumina sequencing. Food components were similar in both IBS and HC groups, except in caffeine consumption. Higher alpha diversity indices and altered gut microbiota were observed in IBS compared to the HC. A negative correlation existed between total observed species and caffeine intake in the HC, and a positive correlation between alpha diversity indices and dietary fiber in the IBS group. Higher alpha diversity and gut microbiota alteration were found in IBS people who consumed caffeine more than 400 mg/d. Moreover, high microbial diversity and alteration of gut microbiota composition in IBS people with high caffeine consumption may be a clue toward the effects of caffeine on the gut microbiome pattern, which warrants further study.

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