Cut-off values of blood mercury concentration in relation to increased body mass index and waist circumference in Koreans

2016 ◽  
Vol 64 (4) ◽  
pp. 867-871 ◽  
Author(s):  
Suhyun Bae ◽  
Soo-Jung Park ◽  
Kyung-Jin Yeum ◽  
Beomhee Choi ◽  
Young-Sang Kim ◽  
...  

Blood mercury (methyl-mercury) from environmental exposure may be related to inflammation in our body. We investigated the cut-off values of blood mercury concentration in relation to increased body mass index (BMI) and waist circumference. On the basis of data obtained from the Korea National Health and Nutrition Examination Survey (KNHANES, 2008–2012), 11,159 subjects (5543 males and 5616 females) were analyzed cross-sectionally. Partial correlation, linear regression, and analysis of covariance (according to the mercury quartile) tests were performed to evaluate the relationship between blood mercury and BMI or waist circumference. In addition, we determined the cut-off values of blood mercury concentration in relation to increased BMI and waist circumference in both genders. Mean values of blood mercury concentration were 5.07±0.07 μg/L in males and 3.59±0.04 μg/L in females. After log transformation of blood mercury, significant (p<0.001) correlation was found between blood mercury concentration and BMI or waist circumference. BMI and waist circumference showed a significant and gradual increase as mercury quartile increased in both genders. Blood mercury concentration was weakly but significantly (p<0.001) associated with BMI and waist circumference. Cut-off values of blood mercury concentration correlated with increased BMI and waist circumference were around 3.95 μg/L in males and 3.40 μg/L in females.

1988 ◽  
Vol 7 (2) ◽  
pp. 129-132 ◽  
Author(s):  
J.C. Sherlock ◽  
M.J. Quinn

Wide discrepancies have been observed between controlled and uncontrolled intake studies of the relationship of blood mercury concentration to intake of mercury. The probable reason for the apparent discrepancies is that the within-subject variation of mercury intake in the uncontrolled studies was almost certainly considerably larger than the within-subject variation in blood mercury concentration; in these circumstances, the apparent slope obtained from a linear regression of blood mercury on intake will invariably be much smaller than the true slope. Studies of the exposure or intake of any substance should therefore include a consideration of the likely within-subject variation in the exposure or intake relative to that in the effect.


2010 ◽  
Vol 69 (11) ◽  
pp. 1976-1982 ◽  
Author(s):  
Hanneke J M Kerkhof ◽  
Sita M A Bierma-Zeinstra ◽  
Martha C Castano-Betancourt ◽  
Moniek P de Maat ◽  
Albert Hofman ◽  
...  

ObjectiveTo study the relationship between serum C reactive protein (CRP) levels, genetic variation in the CRP gene and the prevalence, incidence and progression of radiographic osteoarthritis (ROA) in the Rotterdam Study-I (RS-I). A systematic review of studies assessing the relationship between osteoarthritis (OA) and CRP levels was also performed.MethodsThe association between CRP levels and genetic variation in the CRP gene and ROA was examined in 861 patients with hand OA, 718 with knee OA, 349 with hip OA and 2806 controls in the RS-I using one-way analysis of covariance and logistic regression, respectively. PubMed was searched for articles published between January 1992 and August 2009 assessing the relationship between CRP levels and OA.ResultsIn RS-I the prevalence of knee OA, but not hip OA or hand OA, was associated with 14% higher serum CRP levels compared with controls (p=0.001). This association disappeared after adjustment for age and especially body mass index (BMI) (p=0.33). Genetic variation of the CRP gene was not consistently associated with the prevalence, incidence or progression of OA within RS-I. The systematic review included 18 studies (including RS-I) on serum CRP levels and the prevalence, incidence or progression of OA. Consistently higher crude CRP levels were found in cases of prevalent knee OA compared with controls. No association was observed between serum CRP levels and the prevalence of knee OA following adjustment for BMI (n=3 studies, meta-analysis p value=0.61).ConclusionThere is no evidence of association between serum CRP levels or genetic variation in the CRP gene with the prevalence, incidence or progression of OA independent of BMI.


2020 ◽  
Author(s):  
Wenli Zhang ◽  
Kun He ◽  
Hao Zhao ◽  
Xueqi Hu ◽  
Chunyu Yin ◽  
...  

Abstract Background: The relationship between obesity and prevalent hypertension in older adults has predominantly been estimated using categorical measures of body mass index (BMI) and waist circumference (WC), masking the shape of the dose-response relationship. We aimed to examine the precise relationship of BMI, WC with hypertension, and to assess the appropriate level of BMI and WC for hypertension. Methods: We examined data for 126,123 individuals in Xinzheng city aged ≥60 years from a population based study from January to December 2019. Logistic regression and restricted cubic spline models were applied to assess the relationship and the appropriate level of BMI and WC for hypertension. An additive interaction analysis was used to test synergistic effects between a higher BMI and WC for hypertension. Results: The full-adjusted odds ratios (ORs) with 95% confidence intervals (CIs) of an increase of 1 kg/m2 in BMI and 1 cm in WC for hypertension were 1.084 (1.080-1.087) and 1.025 (1.024-1.027), respectively. Multivariable adjusted restricted cubic spline analyses showed the nonlinear relationships of BMI and WC with hypertension in both men and women (all P<0.001). The risk of hypertension increased steeply with increasing BMI from ≥25 kg/m2 and WC ≥ 88 cm or 86 cm for males and females, respectively. And we observed a significant additive interaction between a higher BMI and WC such that the prevalence of hypertension was significantly enhanced. Conclusion: These findings suggest increased hypertension prevalence in the elderly population with increased BMI and WC. BMI ≤ 25 kg/m2 and WC ≤ 88 cm or 86 cm for males and females may be the best suggestion with regard to primary prevention of hypertension in older adults.


2018 ◽  
Vol 12 (1) ◽  
pp. 80-87
Author(s):  
Jamal Rahmani ◽  
Hamed Kord Varkaneh ◽  
Mirsaeed Yekaninejad ◽  
Ahmad Reza Dorost Motlagh ◽  
◽  
...  

Retos ◽  
2015 ◽  
pp. 21-23
Author(s):  
Saioa Urrutia Gutierrez ◽  
Susana Irazusta Adarraga ◽  
Amaia Balerdi Iztueta ◽  
Oscar González Rodríguez ◽  
José Antonio Arruza Gabilondo

En esta sociedad, caracterizada por el desarrollo del conocimiento, de las tecnologías de la comunicación y de la generalización de los medios de transporte, los niveles de actividad física en la vida cotidiana han descendido. Esto ha traído un aumento del sedentarismo, trastornos relacionados con la salud y la alimentación y obesidad. Diferentes investigaciones han mostrado que tales co-morbilidades pueden derivarse del descenso del nivel de competencia motriz que se viene produciendo en los últimos años y su relación con la percepción de la misma. Ante esta situación, nos hemos propuesto determinar la relación entre el índice de masa corporal y la percepción de competencia. 366 sujetos de 13 a 16 años han participado en estudio. Se ha medido el peso (kgs y la altura (metros) de los sujetos y se les ha aplicado el cuestionario AMPET-R. Los resultados muestran que no hay diferencias significativas en cuanto al índice de masa corporal y que los chicos obtienen  valores más altos en Percepción de competencia motriz que las chicas. Por otro lado, se ha comprobado que el índice de masa corporal y la percepción de competencia se relacionan significativa y negativamente, tanto para los chicos como para las chicas.Palabras clave: Competencia motriz percibida; Índice de Masa Corporal; Sobrepeso; Obesidad.Abstract: This society, characterized by the development of knowledge, communication technologies and the generalization of transports, levels of physical activity in daily life have been declined. This has increased the sedentary lifestyle, health and nutrition related disorders and obesity. Different studies have demonstrated that this kind of co-morbidities may result from the decreased level of motor competence that has been occurring in recent years and the relation to the perception of it. At this point, we proposed to determine the relationship between body mass index and perceived motor competence. 366 subjects from 13 to 16 years have participated in this study. The weight (kg) and height (meters) of participants was measured while they were answering the AMPET-R questionnaire. The results show that there are not significant differences between different levels of body mass index and boys obtained higher values for perceived motor competence than girls. On the other hand, it has been show that body mass index and perceived motor competence are related significantly but negatively, for both girls and boys.Key words: Perceived motor competence; body mass index; overweight; obesity.


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