1 Relationship between body mass index and blood uric acid level in chinese female population

2019 ◽  
Author(s):  
Zhuang Geng ◽  
JingWei Chi ◽  
Kui Che ◽  
JianXia Hu ◽  
Yan Zhao ◽  
...  
2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Jeffrey Christian Mahardhika ◽  
R.M. Suryo Anggoro

Background Gout arthritis associates with many comorbodities such as hyperuricemia, hypertension, hyperglycemia, obesity, and dyslipidemia, which are also factors for the development of/or predisposition factors of chronic kidney diseases (CKD). Albuminuria is a predictor factors for CKD. Screening for albuminuria is needed to be done in patients with high risk of CKD. This research was conducted to examine the prevalence of albuminuria and the associated factors in gout arthritis patients.Methods This research was a cross-sectional study from gout arthritis patients’ medical records in Cipto Mangunkusumo Hospital. We included all gout patients who treated within 2011−2015. Subjects with chronic kidney disease, in kidney replacement therapy, hypertension ≥ 10 years, and diabetes ≥ 5 years were excluded. Albuminuria was determined by urine dipstick result of protein ≥ 1+. Factors associated were age, sex, hyperuricemia, hypertension, stage of hypertension, hyperglycemia, obesity, dyslipidemia, uric acid level, and body mass index (BMI). Data associated with the factors were recorded and the associations were tested with chi square, fisher’s exact, or independent t-test.Results from 54 subjects included in this research, the prevalence of albuminuria was 20.4%. There were no significant associations between all factors and albuminuria tested by chi square and fisher’s exact test. Independent t-test’s results also showed no significant associations between all the factors and albuminuriaConclusion The prevalence of albuminuria in gout arthritis patient was 20.4%. There were no significant associatons between age, sex, hyperuricemia, hypertension, hyperglycemia, obesity, dyslipidemia, uric acid level, and body mass index (BMI) tested with albuminuria in gout arthritis patients in Cipto Mangunkusumo Hospital from 2011−2015.Keywords: Prevalence, Albuminuria, Gout Arthritis, Risk Factors


2017 ◽  
Vol 5 (2) ◽  
Author(s):  
Paterick R. Rampi ◽  
Youla A. Assa ◽  
Yanti M. Mewo

Abstract: Diseases caused by high uric acid levels are still commonly found in societies world wide. There is a correlation between uric acid level and increased body mass index (BMI). Higher body mass index in this case overweight and obesity is associated with higher risk of insulin resistance and excessive leptin production which may contribute to hyperuricemia. This study was aimed to obtain the profile of serum uric acid level among students with a BMI of ≥23 kg/m2 at Faculty of Medicine, Sam Ratulangi University. This was a descriptive study with a cross sectional design. Samples were obtained by using total sampling method. There were 53 respondents that met the inclusion and exclusion criteria. The results showed that there were 48 respondents (90.6%) whose serum uric acid levels were within normal limits, one respondent (1.9%) with hyperuricemia, and four respondents (7.5%) with hypouricemia. Conclusion: The majority of respondents had uric acid level within normal limit.Keywords: serum uric acid, body mass index, students Abstrak: Penyakit yang disebabkan akibat tingginya kadar asam urat masih banyak diderita oleh masyarakat dunia sekarang ini. Terdapat hubungan antara kadar asam urat dengan peningkatan indeks massa tubuh (IMT). Semakin tinggi indeks massa tubuh dalam hal ini overweight dan obesitas berhubungan dengan semakin tinggi juga risiko terjadinya resistensi insulin dan produksi leptin yang berlebih sehingga keadaan ini dapat berkontribusi menimbulkan hiperurisemia. Tujuan penelitian ini untuk mengetahui gambaran kadar asam urat serum pada mahasiswa dengan IMT ≥23 kg/m2 di Fakultas Kedokteran Universitas Sam Ratulangi. Jenis penelitian ialah deskriptif dengan desain potong lintang. Pengambilan sampel dengan menggunakan teknik total sampling. Terdapat 53 responden yang memenuhi kriteria inklusi dan eksklusi. Hasil penelitian memperlihatkan 48 responden (90,6%) memiliki kadar asam urat serum dalam batas normal, satu responden (1,9%) dengan hiperurisemia, dan empat responden (7,5%) dengan hipourisemia. Simpulan: Sebagian besar responden memiliki kadar asam urat serum dalam batas normal.Kata kunci: asam urat serum, indeks massa tubuh, mahasiswa


Medicine ◽  
2020 ◽  
Vol 99 (9) ◽  
pp. e19418 ◽  
Author(s):  
Lin Zhang ◽  
Jin-Long Li ◽  
Li-Li Zhang ◽  
Lei-Lei Guo ◽  
Hong Li ◽  
...  

2019 ◽  
Vol 26 (10) ◽  
pp. 1733-1737
Author(s):  
Sardar Muhammad Al-Fareed Zafar ◽  
Rahat Naseem ◽  
Samia Jawed ◽  
Saima Mukhtar ◽  
Farhat Ijaz ◽  
...  

Body mass index is the fat content of body whereas hyperuricemia is the condition when serum uric acid level crosses the optimum normal level. Increase in BMI may influence serum uric acid. Objective: To find out the relationship of BMI with serum uric acid level in local population. Study Design: Cross sectional study. Setting: Lady Aitchison hospital Lahore. Period: March 2017- August 2017. Material and Methods: Written informed consent was taken prior to data collection. Detailed history was asked and weight in kilograms and height in meters was noted. Body mass index was calculated. Uric acid was measured by uricase method after taking 1 ml venous blood under aseptic measures. Results: Body mass index and serum uric acid of the subjects were compared with the standard values that were 24.99kg/m2 and 5.7mg/dl and statistical analysis showed a significant difference (p-0.023 and p-0.000) respectively. Simple linear regression revealed 0.391 units change in serum uric acid level with one unit change in BMI. Conclusion: Serum uric acid increased with increase in BMI.


2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Jeffrey Christian Mahardhika ◽  
R.M. Suryo Anggoro

Background Gout arthritis associates with many comorbodities such as hyperuricemia, hypertension, hyperglycemia, obesity, and dyslipidemia, which are also factors for the development of/or predisposition factors of chronic kidney diseases (CKD). Albuminuria is a predictor factors for CKD. Screening for albuminuria is needed to be done in patients with high risk of CKD. This research was conducted to examine the prevalence of albuminuria and the associated factors in gout arthritis patients.Methods This research was a cross-sectional study from gout arthritis patients’ medical records in Cipto Mangunkusumo Hospital. We included all gout patients who treated within 2011−2015. Subjects with chronic kidney disease, in kidney replacement therapy, hypertension ≥ 10 years, and diabetes ≥ 5 years were excluded. Albuminuria was determined by urine dipstick result of protein ≥ 1+. Factors associated were age, sex, hyperuricemia, hypertension, stage of hypertension, hyperglycemia, obesity, dyslipidemia, uric acid level, and body mass index (BMI). Data associated with the factors were recorded and the associations were tested with chi square, fisher’s exact, or independent t-test.Results from 54 subjects included in this research, the prevalence of albuminuria was 20.4%. There were no significant associations between all factors and albuminuria tested by chi square and fisher’s exact test. Independent t-test’s results also showed no significant associations between all the factors and albuminuriaConclusion The prevalence of albuminuria in gout arthritis patient was 20.4%. There were no significant associatons between age, sex, hyperuricemia, hypertension, hyperglycemia, obesity, dyslipidemia, uric acid level, and body mass index (BMI) tested with albuminuria in gout arthritis patients in Cipto Mangunkusumo Hospital from 2011−2015.Keywords: Prevalence, Albuminuria, Gout Arthritis, Risk Factors


1984 ◽  
Vol 33 (2) ◽  
pp. 237-242 ◽  
Author(s):  
E. Inouye ◽  
K.S. Park ◽  
A. Asaka

AbstractApplying newly devised model, heritability (VA/VP) of plasma uric acid level, corrected for age and sex and standardized, was estimated at 0.8 in families consisting of twin parents, spouses and children. Correlation between spouses due to common genotype (ρ) was approximately 0.1, and variance due to common familial environment (VEC/Vp) was -0.3. Analysis of families of selected twin children and their parents resulted in two estimates of heritability: approximately 0.7 and 0.3, ρ being 0.34 and 0.04, and VEC/Vp being 0.04 and 0.34, respectively. Regression of IQ (y) on corrected and standardized plasma uric acid level (x) in the twin children was y = 5.56x + 123, correlation being 0.334 (p < 0.025). The result indicates a genetic basis of blood uric acid level, which may have resulted from polymorphisms in purine metabolism pathway, end product of which is uric acid in man. The significant correlation between plasma uric acid level and IQ suggests a contribution of partly common gene loci to the two quantitative traits.


Heart ◽  
2013 ◽  
Vol 99 (Suppl 3) ◽  
pp. A177.1-A177
Author(s):  
Zhang Quan-Yu ◽  
Han yaling

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