scholarly journals Prevalence of Albuminuria and Associated Factors among Gout Arthritis Patients in Cipto Mangunkusumo Hospital

2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Jeffrey Christian Mahardhika ◽  
R.M. Suryo Anggoro
Keyword(s):  
Body Mass Index ◽  
Uric Acid ◽  
Body Mass ◽  
Uric Acid Level ◽  
Associated Factors ◽  
Acid Level ◽  
Kidney Diseases ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional

Background Gout arthritis associates with many comorbodities such as hyperuricemia, hypertension, hyperglycemia, obesity, and dyslipidemia, which are also factors for the development of/or predisposition factors of chronic kidney diseases (CKD). Albuminuria is a predictor factors for CKD. Screening for albuminuria is needed to be done in patients with high risk of CKD. This research was conducted to examine the prevalence of albuminuria and the associated factors in gout arthritis patients.Methods This research was a cross-sectional study from gout arthritis patients’ medical records in Cipto Mangunkusumo Hospital. We included all gout patients who treated within 2011−2015. Subjects with chronic kidney disease, in kidney replacement therapy, hypertension ≥ 10 years, and diabetes ≥ 5 years were excluded. Albuminuria was determined by urine dipstick result of protein ≥ 1+. Factors associated were age, sex, hyperuricemia, hypertension, stage of hypertension, hyperglycemia, obesity, dyslipidemia, uric acid level, and body mass index (BMI). Data associated with the factors were recorded and the associations were tested with chi square, fisher’s exact, or independent t-test.Results from 54 subjects included in this research, the prevalence of albuminuria was 20.4%. There were no significant associations between all factors and albuminuria tested by chi square and fisher’s exact test. Independent t-test’s results also showed no significant associations between all the factors and albuminuriaConclusion The prevalence of albuminuria in gout arthritis patient was 20.4%. There were no significant associatons between age, sex, hyperuricemia, hypertension, hyperglycemia, obesity, dyslipidemia, uric acid level, and body mass index (BMI) tested with albuminuria in gout arthritis patients in Cipto Mangunkusumo Hospital from 2011−2015.Keywords: Prevalence, Albuminuria, Gout Arthritis, Risk Factors

scholarly journals Prevalence of Albuminuria and Associated Factors among Gout Arthritis Patients in Cipto Mangunkusumo Hospital

2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Jeffrey Christian Mahardhika ◽  
R.M. Suryo Anggoro
Keyword(s):  
Body Mass Index ◽  
Uric Acid ◽  
Body Mass ◽  
Uric Acid Level ◽  
Associated Factors ◽  
Acid Level ◽  
Kidney Diseases ◽  
Protein A ◽  
Chi Square ◽  
Cross Sectional

Background Gout arthritis associates with many comorbodities such as hyperuricemia, hypertension, hyperglycemia, obesity, and dyslipidemia, which are also factors for the development of/or predisposition factors of chronic kidney diseases (CKD). Albuminuria is a predictor factors for CKD. Screening for albuminuria is needed to be done in patients with high risk of CKD. This research was conducted to examine the prevalence of albuminuria and the associated factors in gout arthritis patients.Methods This research was a cross-sectional study from gout arthritis patients’ medical records in Cipto Mangunkusumo Hospital. We included all gout patients who treated within 2011−2015. Subjects with chronic kidney disease, in kidney replacement therapy, hypertension ≥ 10 years, and diabetes ≥ 5 years were excluded. Albuminuria was determined by urine dipstick result of protein ≥ 1+. Factors associated were age, sex, hyperuricemia, hypertension, stage of hypertension, hyperglycemia, obesity, dyslipidemia, uric acid level, and body mass index (BMI). Data associated with the factors were recorded and the associations were tested with chi square, fisher’s exact, or independent t-test.Results from 54 subjects included in this research, the prevalence of albuminuria was 20.4%. There were no significant associations between all factors and albuminuria tested by chi square and fisher’s exact test. Independent t-test’s results also showed no significant associations between all the factors and albuminuriaConclusion The prevalence of albuminuria in gout arthritis patient was 20.4%. There were no significant associatons between age, sex, hyperuricemia, hypertension, hyperglycemia, obesity, dyslipidemia, uric acid level, and body mass index (BMI) tested with albuminuria in gout arthritis patients in Cipto Mangunkusumo Hospital from 2011−2015.Keywords: Prevalence, Albuminuria, Gout Arthritis, Risk Factors

scholarly journals Gambaran Kadar Asam Urat Serum pada Mahasiswa dengan Indeks Massa Tubuh ≥23 kg/m2 di Fakultas Kedokteran Universitas Sam Ratulangi

2017 ◽  
Vol 5 (2) ◽  
Author(s):  
Paterick R. Rampi ◽  
Youla A. Assa ◽  
Yanti M. Mewo
Keyword(s):  
Body Mass Index ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Body Mass ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Overweight And Obesity ◽  
Cross Sectional ◽  
Normal Limits

Abstract: Diseases caused by high uric acid levels are still commonly found in societies world wide. There is a correlation between uric acid level and increased body mass index (BMI). Higher body mass index in this case overweight and obesity is associated with higher risk of insulin resistance and excessive leptin production which may contribute to hyperuricemia. This study was aimed to obtain the profile of serum uric acid level among students with a BMI of ≥23 kg/m2 at Faculty of Medicine, Sam Ratulangi University. This was a descriptive study with a cross sectional design. Samples were obtained by using total sampling method. There were 53 respondents that met the inclusion and exclusion criteria. The results showed that there were 48 respondents (90.6%) whose serum uric acid levels were within normal limits, one respondent (1.9%) with hyperuricemia, and four respondents (7.5%) with hypouricemia. Conclusion: The majority of respondents had uric acid level within normal limit.Keywords: serum uric acid, body mass index, students Abstrak: Penyakit yang disebabkan akibat tingginya kadar asam urat masih banyak diderita oleh masyarakat dunia sekarang ini. Terdapat hubungan antara kadar asam urat dengan peningkatan indeks massa tubuh (IMT). Semakin tinggi indeks massa tubuh dalam hal ini overweight dan obesitas berhubungan dengan semakin tinggi juga risiko terjadinya resistensi insulin dan produksi leptin yang berlebih sehingga keadaan ini dapat berkontribusi menimbulkan hiperurisemia. Tujuan penelitian ini untuk mengetahui gambaran kadar asam urat serum pada mahasiswa dengan IMT ≥23 kg/m2 di Fakultas Kedokteran Universitas Sam Ratulangi. Jenis penelitian ialah deskriptif dengan desain potong lintang. Pengambilan sampel dengan menggunakan teknik total sampling. Terdapat 53 responden yang memenuhi kriteria inklusi dan eksklusi. Hasil penelitian memperlihatkan 48 responden (90,6%) memiliki kadar asam urat serum dalam batas normal, satu responden (1,9%) dengan hiperurisemia, dan empat responden (7,5%) dengan hipourisemia. Simpulan: Sebagian besar responden memiliki kadar asam urat serum dalam batas normal.Kata kunci: asam urat serum, indeks massa tubuh, mahasiswa

scholarly journals AB0932 FACTORS IN ACHIEVING TARGET SERUM URIC ACID LEVELS IN OUTPATIENT GOUT MANAGEMENT IN A MALAYSIAN TERTIARY RHEUMATOLOGY CENTRE

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1766.2-1766
Author(s):  
M. H. Mustapha ◽  
H. Baharuddin ◽  
N. Zainudin ◽  
S. S. Ch’ng ◽  
H. Mohd Yusoof ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Cross Sectional Study ◽  
British Society ◽  
Treat To Target ◽  
Tophaceous Gout ◽  
Cross Sectional ◽  
The Mean

Background:Gout is one of the most common inflammatory arthropathies. A target serum uric acid of less than 300µmol/l is recommended when tophi are present, and less than 360µmol/l for non-tophaceous gout. Urate-lowering therapy (ULT) should be titrated until the target is achieved and long-term maintenance of the target concentration is recommended. Although ULT has been proven to reduce the uric acid level, less than half of treated patients achieved the target serum uric acid (sUA) in real-world clinical practice.Objectives:To assess the mean treat-to-target achievement in outpatient management of gout by the tertiary rheumatology centre and to identify factors influencing the success rate.Methods:Retrospective cross-sectional study of all patients with gout attending out-patient clinics in a rheumatology referral centre from 1stJanuary 2018 until 31stDecember 2018. Electronic medical records were reviewed. The successful target achievement is defined as mean of all available sUA in 2018 which is ≤360 and ≤300µmol/l for non-tophaceous and tophaceous gout respectively. Chronic kidney disease (CKD) is defined as glomerular filtration rate of less than 60ml/min.Results:There were 251 patients analysed with mean age of 56.3±13.8 years and disease duration of 10.5±9.2 years. Majority were males (215, 85.7%) and 133 (53%) patients had tophaceous gout. The rate of success achieving the target SUA level of ≤360 and ≤300µmol/l were 33.9% (40) and 15.8% (21) in non-tophaceous and tophaceous gout respectively. However, in patients who are compliant, the target sUA achieved is 52.4% (33) and 31.7% (19) in non-tophaceous and tophaceous gout respectively. Characteristics of patients who achieved the targeted sUA were patients of more than 50 years old (48, 78.7%), without family history of gout (29, 65.9%), were prescribed colchicine prophylaxis upon initiating ULT (46, 76.7%), with absence of joint erosions (34, 73.9%) and those with normal creatinine clearance (40, 65.5%). There were 120 (48.4%) patients who were compliant to ULT. In 42 compliant patients who achieved target sUA, the mean allopurinol dose is 289.66mg±101.2 and 369.23mg±175 in non-tophaceous and tophaceous gout respectively. Sub-analysis in 31 compliant CKD patients, revealed no difference in allopurinol dose between those who achieved versus non-achieved target sUA (mean 243mg versus 263mg respectively). However, we noted that 11 (61%) CKD patients with tophi did not achieved target sUA at dose less than 300mg allopurinol. Lower achievement of target sUA was significantly associated with presence of tophi (p=0.001), poor compliance (p= 0.000) and presence of more than one comorbidity (p=0.041).Conclusion:There are several challenges in achieving target uric acid level contributed by both patient and clinician factors such as compliance, presence of comorbidity and ULT dose. Our study suggests that higher dosage of allopurinol is required in patients with tophaceous gout, with or without renal impairment. However, the limitation of this study is, the small number of subjects which therefore needsfurtherinvestigation.References:[1]Roddy, E., Packham, J., Obrenovic, K., Rivett, A., & Ledingham, J. M. (2018). Management of gout by UK rheumatologists: a British Society for Rheumatology national audit. Rheumatology, 57(5), 826–830.[2]Katayama A, Yokokawa H, Fukuda H, et al. Achievement of Target Serum Uric Acid Levels and Factors Associated with Therapeutic Failure among Japanese Men Treated for Hyperuricemia/Gout. Intern Med. 2019;58(9):1225–1231.Disclosure of Interests:Mariam Hamid Mustapha: None declared, Hazlyna Baharuddin Speakers bureau: Sanofi, J&J, Norliza Zainudin: None declared, Shereen Suyin Ch’ng Speakers bureau: Novartis, Pfizer, GSK, Habibah Mohd Yusoof: None declared, Ing Soo Lau: None declared, Mollyza Mohd Zain: None declared, Azmillah Rosman: None declared

scholarly journals POLA KONSUMSI SUMBER PURIN, AKTIVITAS FISIK DAN STATUS GIZI DENGAN KADAR ASAM URAT PADA LANSIA DI PUSKESMAS KECAMATAN MAKASAR JAKARTA

2020 ◽  
Vol 4 (1) ◽  
pp. 84
Author(s):  
Gina Ganda Fitriana ◽  
Adhila Fayasari
Keyword(s):  
Physical Activity ◽  
Uric Acid ◽  
Nutritional Status ◽  
Uric Acid Level ◽  
Acid Level ◽  
Consumption Pattern ◽  
Chi Square ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Significant Difference

Degenerative processes can decrease the endurance in elderly that leads to health problem such as gout. Gout is a metabolic disorder, which is indicated by an increase uric acid in bloodstream (hyperuricemia). Factors affecting high level of uric acid are purine intake, physical activity and nutritional status. The aim of this study was to analyze the relationship between consumption pattern of purine source food, nutritional status and physical activity with uric acid level in elderly. The study design was cross sectional. The sample consisted of 100 subyekts at Puskesmas Kecamatan Makasar. The analytical used chi square. Patterns of food consumption of purine sources were measured using FFQ questionnaires which was then cut off into into 2 categories: low-moderate purine category with score <55 and high purine category with a score of ≥55 physical activity and nutritional status were measured using questionnaires, uric acid levels was obtained by looking at laboratory results or from patients' medical records. There was 10% of subyekts withlo- moderate uric acid levels and 90% of subyekts with high purine consumption pattern. Based on the results of chi square test there was a significant difference (p <0.05) between the consumption pattern of purine source food with normal uric acid and high uric acid. There was a relationship between consumption pattern of purine food source with uric acid level in elderly.

scholarly journals Body mass index and age of menarche in young girls

2012 ◽  
Vol 52 (6) ◽  
pp. 309
Author(s):  
Dina Olivia ◽  
Melda Deliana ◽  
Supriatmo Supriatmo ◽  
Hakimi Hakimi ◽  
Siska Mayasari Lubis
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Age At Onset ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Young Girls ◽  
Chi Square Test ◽  
Obese Subjects ◽  
Age Of Menarche

Background Currently the age at onset of menarche is earlierthan in the past. Nutritional status has an important role inthe onset of menarche. Past studies have shO\vn an associationbetween body mass index (BMI) in young girls and earlier onsetof menarche.Objective To assess an association between BMI and age at onsetof menarche.Methods This cross􀁈sectional study was conducted in younggirls aged 10 to 15 years from Immanuel Elementary and JuniorHigh School, Medan in June 2010. We used purposive samplingto recruit subjects. After subjects underwent height and weightmeasurements, we calculated their BMIs. The association betweenBMI and initial age of menarche was assessed by Chi square test(P<O.05 v.ith a 95% confidence interval).Results Eighty􀁈five subjects participated in this study. There were44 subjects in the 5th􀀊85th percentile ofBMI (nonnoweight), 19subjects with 85th􀀊95th percentile of BMI (overweight) and 12subjects in the> 95th percentile ofBMI (obese). All obese subjectshad an earlier onset of menarche at ages 1O􀁈 11 years, comparedto that of non􀁈obese subjects (P=O.OOOl).Conclusion Young girls v.ith BMI > 95th percentile had anearlier age at onset of menarche than young girls v.ith lower BMls.[Paediatr lndanes. 2012,52:309-12].

scholarly journals Correlation nutritional status with uric acid level in Minangkabau men ethnicity

2018 ◽  
Vol 7 (1) ◽  
pp. 131
Author(s):  
Desmawati Desmawati ◽  
Yuniar Lestari ◽  
Ulya Uti Fasrini ◽  
Delmi Sulastri
Keyword(s):  
Uric Acid ◽  
Nutritional Status ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Significant Relationship ◽  
Acid Level ◽  
Laboratory Data ◽  
Overweight And Obesity ◽  
Chi Square ◽  
Cross Sectional

Background: Hyperuricemia is a predictor of metabolic syndrome influenced by many factors, one of which is nutritional status. A highly prevalence overweight and obesity in ethnic Minangkabau is quite high which can increase the prevalence of hyperuricemia. This study aims to determine the relationship of nutritional status intake with Minangkabau ethnic male uric acid levels.Methods: This study used a cross-sectional design, done in August to November 2016. Nutritional status was obtained through the measurement of body mass index (BMI) based on height and weight. The uric acid level examined in the Prodia laboratory. Data were analyzed by using chi-square test.Results: Most of subject were obesities. A total of 21% subjects suffers hyperuricemia. Statistic test results showed that there was a significant relationship between nutritional status and serum uric acid levels (p <0.0001).Conclusions: There was a significant relationship between nutritional status and serum uric acid levels in Minangkabau ethnic men in Padang city.

scholarly journals Body Mass Index and Dysmenorrhea in Female Teenagers

2019 ◽  
Vol 4 (1) ◽  
pp. 21
Author(s):  
Ainun Zulkiah Surur ◽  
Melda Putri ◽  
Asdar Fajrin Multazam
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Young Women ◽  
Cross Sectional Study ◽  
Primary Data ◽  
Menstrual Pain ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Female Teenagers

Dysmenorrhea is a problem experienced by more than 50% of women in each country. Pain occurs in the lower abdomen, sometimes accompanied by nausea, vomiting, dizziness and mood changes. This condition causes an increase in absenteeism in school, disruption in learning activities that affects achievements in academic and nonacademic fields. One factor that is often associated with the incidence of dysmenorrhea is an abnormal body mass index (overweight and underweight). This study aims to determine the relationship of body mass index with the degree of pain menstruation (dysmenorrhea) in young women in SMA Negeri 21 Makassar. This research is a descriptive cross-sectional study involving 110 respondents based on the purposive sampling method and carried out in February-March 2019. The data taken is primary data through measurements of body mass index based on body weight and height. After that, a normal, overweight and underweight grouping is done. Measurement of menstrual pain level is done using Visual Analog Scale (VAS). Data analysis was performed using Chi square test and the value of p = 0.00 was obtained. From this results, significant conclusions can be drawn because the value of p < 0.05 indicates that there is a significant relationship between body mass index and degree of menstrual pain (dysmenorrhoea) in young women in SMA Negeri 21 Makassar. Keywords: Dysmenorrhea, Body Mass Index, Adolescent

1 Relationship between body mass index and blood uric acid level in chinese female population

2019 ◽  
Author(s):  
Zhuang Geng ◽  
JingWei Chi ◽  
Kui Che ◽  
JianXia Hu ◽  
Yan Zhao ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Uric Acid ◽  
Body Mass ◽  
Uric Acid Level ◽  
Acid Level ◽  
Female Population ◽  
Blood Uric Acid
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