scholarly journals Association between exercise-induced change in body composition and change in cardiometabolic risk factors in postmenopausal South Asian women

2016 ◽  
Vol 41 (9) ◽  
pp. 931-937 ◽  
Author(s):  
Iris A. Lesser ◽  
Jordan A. Guenette ◽  
Amandah Hoogbruin ◽  
Dawn C. Mackey ◽  
Joel Singer ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Composition ◽  
South Asian ◽  
Cardiometabolic Risk ◽  
South Asians ◽  
Cardiometabolic Risk Factors ◽  
Asian Women ◽  
South Asian Women ◽  
Exercise Induced

The South Asian population suffers from a high prevalence of type 2 diabetes and cardiovascular disease (CVD). A unique obesity phenotype of elevated visceral adipose tissue (VAT) is associated with CVD risk among South Asians. Exercise-induced reduction in VAT and body fat is an effective mechanism to improve cardiometabolic risk factors but this has not been shown in South Asians. Whether exercise-induced changes in measurements such as waist circumference (WC) are independently related to changes in cardiometabolic risk factors in South Asians is unknown. Multi-slice computed tomography scanning was used to assess VAT, cardiometabolic risk factors through a fasting blood sample, and body fat using dual-energy X-ray absorptiometry. Forty- nine postmenopausal South Asian women who participated in two 12-week aerobic exercise programs were included. Bivariate correlations were used to assess associations between change in cardiometabolic risk factors and change in body composition. Regression analyses were conducted with change in glucose, insulin, and homeostatic model assessment of insulin resistance (HOMA-IR) as dependent variables and change in body composition as independent variables of interest. There were significant associations between changes in fasting insulin, glucose, and HOMA-IR with change in VAT. The association between change in VAT and these cardiometabolic risk factors was independent of change in other body composition variables of interest. South Asian women should be encouraged to engage in aerobic activity to reduce their risk of type 2 diabetes and CVD, and physicians should be aware of improvements in glucose regulation with exercise training not observed through reductions in WC.

scholarly journals Is the “South Asian Phenotype” Unique to South Asians? Comparing Cardiometabolic Risk Factors in the CARRS and NHANES Studies

Global Heart ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. 89 ◽  
Author(s):  
Shivani A. Patel ◽  
Roopa Shivashankar ◽  
Mohammed K. Ali ◽  
R.M. Anjana ◽  
M. Deepa ◽  
...  
Keyword(s):  
Risk Factors ◽  
South Asian ◽  
Cardiometabolic Risk ◽  
South Asians ◽  
Cardiometabolic Risk Factors ◽  
The South

scholarly journals Effects of Nine-Month Lifestyle Intervention on Cardiometabolic Risk Factors: Sex Differences in Obese Individuals

Obesities ◽  
2021 ◽  
Vol 1 (1) ◽  
pp. 29-35
Author(s):  
Florent Besnier ◽  
Anil Nigam ◽  
Martin Juneau ◽  
Valérie Guilbeault ◽  
Elise Latour ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Composition ◽  
Sex Differences ◽  
Body Mass ◽  
Cardiometabolic Risk ◽  
Interval Training ◽  
Cardiometabolic Risk Factors ◽  
Obese Women ◽  
Baseline Values ◽  
High Intensity Interval

Limited data is available on the sex differences and individual responses of cardiometabolic parameters adjusted with potential confounders (i.e. sex, age, baseline values) after a longer term Mediterranean diet (MedD) and high intensity interval training (HIIT) in obese subjects. The objective of this study was to compare the effects of nine-month MedD counseling and supervised HIIT on cardiometabolic risk factors and individual responses in obese women (n = 99) and obese men (n = 35). Body composition (body mass, fat mass, lean body mass, waist circumference), cardiorespiratory fitness (METs), and cardiometabolic risk factors (blood pressure, blood sample variables) were measured at baseline and after nine months of a program combining MedD and HIIT two to three times a week. When adjusted with sex, age, and baseline values, obese women similarly improved their body composition, METs, and cardiometabolic risk factors vs. obese men. The proportion of responders according to clinical cutoff levels were the same in obese women and men. A longer MedD and HIIT intervention similarly improves body composition, cardiometabolic risk factors, and individual responses in obese women and men, even after adjustment of confounders (sex, age, baseline value).

scholarly journals Functional high-intensity exercise training ameliorates insulin resistance and cardiometabolic risk factors in type 2 diabetes

2018 ◽  
Vol 103 (7) ◽  
pp. 985-994 ◽  
Author(s):  
Ciarán E. Fealy ◽  
Stephan Nieuwoudt ◽  
Julie A. Foucher ◽  
Amanda R. Scelsi ◽  
Steven K. Malin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Exercise Training ◽  
High Intensity ◽  
Cardiometabolic Risk ◽  
High Intensity Exercise ◽  
Cardiometabolic Risk Factors

80-OR: Treatment with Once-Weekly Semaglutide 2.4 mg Improves Cardiometabolic Risk Factors in Adults with Overweight/Obesity and Type 2 Diabetes: STEP 2 Post-hoc Analysis

Diabetes ◽  
2021 ◽  
Vol 70 (Supplement 1) ◽  
pp. 80-OR
Author(s):  
ROBERT F. KUSHNER ◽  
MELANIE J. DAVIES ◽  
JOHN DEANFIELD ◽  
W. TIMOTHY GARVEY ◽  
OLE JEPPESEN ◽  
...  
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Post Hoc Analysis ◽  
Post Hoc

scholarly journals Effects of Extreme Weight Loss on Cardiometabolic Health in Children With Metabolic Syndrome: A Metabolomic Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Jingxin Liu ◽  
Lin Zhu ◽  
Jing Liao ◽  
Xiaoguang Liu
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Weight Loss ◽  
Body Composition ◽  
Organic Acids ◽  
Cardiometabolic Risk ◽  
The Body ◽  
Cardiometabolic Risk Factors ◽  
Plasma Metabolites ◽  
Cardiometabolic Health

Objectives: To evaluate the effect of extreme weight loss programs on circulating metabolites and their relationship with cardiometabolic health in children with metabolic syndrome.Methods: This study was a quasi-experimental design with a pretest and post-test. Thirty children with metabolic syndrome and aged 10–17years were recruited to an extreme weight loss program (i.e., exercise combined with diet control). The primary outcomes included plasma metabolites, body composition, and cardiometabolic risk factors. A total of 324 metabolites were quantitatively detected by an ultra-performance liquid chromatography coupled to tandem mass spectrometry system, and the variable importance in the projection (VIP) value of each metabolite was calculated by the orthogonal projection to latent structures discriminant analysis. The fold change (FC) and p value of each metabolite were used to screen differential metabolites with the following values: VIP>1, p value<0.05, and |log2FC|>0.25. Pathway enrichment and correlation analyses between metabolites and cardiometabolic risk factors were also performed.Result: A large effect size was observed, presenting a weight loss of −8.9kg (Cohen’s d=1.00, p<0.001), body mass index reduction of −3.3kg/m2 (Cohen’s d=1.47, p<0.001), and body fat percent reduction of −4.1 (%) (Cohen’s d=1.22, p<0.001) after the intervention. Similar improvements were found in total cholesterol (Cohen’s d=2.65, p<0.001), triglycerides (Cohen’s d=2.59, p<0.001), low-density lipoprotein cholesterol (Cohen’s d=2.81, p<0.001), glucose metabolism, and blood pressure. A total of 59 metabolites were changed after the intervention (e.g., aminoacyl-tRNA biosynthesis, glycine, serine, and threonine metabolism; nitrogen metabolism, tricarboxylic acid cycle, and phenylalanine, tyrosine, and tryptophan biosynthesis). The changes in metabolites (e.g., amino acids, fatty acids, organic acids, and carnitine) were related to lipid metabolism improvement (p<0.05). Organic acids and carnitines were associated with changes in the body composition (p<0.05).Conclusion: Exercise combined with dietary control improved the body composition and cardiometabolic health in children with metabolic syndrome, and these changes may be related to plasma metabolites.

scholarly journals Differences in Body Composition Convey a Similar Risk of Type 2 Diabetes Among Different Ethnic Groups With Disparate Cardiometabolic Risk—The HELIUS Study

2021 ◽  
Author(s):  
Marleen Zethof ◽  
Charlotte M. Mosterd ◽  
Didier Collard ◽  
Henrike Galenkamp ◽  
Charles Agyemang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Body Composition ◽  
Ethnic Groups ◽  
South Asian ◽  
Cardiometabolic Risk ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
C Statistic ◽  
Helius Study

<b>Objective</b>: Studies have shown a disparate association between body composition and the risk of type 2 diabetes. We assessed whether associations between differences in body composition and type 2 diabetes vary among ethnic groups with disparate cardiometabolic risk. <p><b>Research Design and Methods: </b>We used data from the HELIUS study, including individuals aged 18-70 of<b> </b>African Surinamese (n=3997), South-Asian Surinamese (n=2956), Turkish (n=3546), Moroccan (n=3850), Ghanaian (n=2271) and Dutch (n=4452) origin living in Amsterdam. Type 2 diabetes was defined using the World Health Organization criteria. Logistic regression was used to assess the relation between body composition and type 2 diabetes. Waist-hip ratio, waist circumference, BMI and body fat percentage by bio-electrical impedance were used to estimate body composition.</p> <p><b>Results: </b>Per unit change in BMI only Ghanaian [OR 0.94 (95% CI 0.89-0.99)] and Moroccan [0.94 (0.89-0.99)] women had a smaller increase in type 2 diabetes per unit change in BMI compared to the Dutch population, while OR for body fat percentage were 0.94 (0.89-1.00) for Ghanaian, 0.93 (0.88-0.99) for Moroccan and 0.95 (0.90-1.00) for South-Asian Surinamese women. There was no interaction between WHR and ethnicity on the risk of type 2 diabetes, and there were no differences in men. WHR had the highest precision in predicting type 2 diabetes in both men (c-statistic=0.78) and women (c-statistic=0.81). </p> <b>Conclusions: </b>The<b> </b>association between differences in body composition and type 2 diabetes is roughly the same in all ethnic groups. WHR seems the most reliable and consistent predictor of type 2 diabetes regardless of ethnic background.<b> </b>

Baru Nut Intake and Resistance Training Practice Have Potential to Reduce the Cardiometabolic Risk Factors in Type 2 Diabetes

2021 ◽  
Vol 17 ◽  
Author(s):  
John Sebastião Cardoso da Silva ◽  
Maria Sebastiana Silva ◽  
Maria Margareth Veloso Naves
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Resistance Training ◽  
Cardiometabolic Risk ◽  
Nutritional Composition ◽  
Cardiometabolic Risk Factors ◽  
Cardiometabolic Health

Background: Type 2 diabetes mellitus (T2DM) is a disease associated with several cardiometabolic risk factors (CMRF). There is strong evidence about the benefits of oilseeds intake and the practice of resistance training (RT) in the prevention and treatment of T2DM and its associated CMRF. However, no study has evaluated the combination of these interventions yet. Baru nut, an oilseed native to the Brazilian Cerrado, stands out among oilseeds due to its healthy nutritional composition, which have the potential to reduce CMRF in T2DM. RT, in turn, provides positive changes in the composition and metabolism of muscle cells, which contributes to improving cardiometabolic health. Objective: This review aimed to summarize the effects and mechanisms related to the intake of baru nut and the practice of RT in reducing CMRF in T2DM. Method: Literature research was performed using the keywords "type 2 diabetes mellitus", "Dipteryx alata Vog", "nuts", "physical exercise" and "resistance training", isolated or associated, in Web of Science and Pubmed databases. Results: Baru nut is an oilseed with high density of nutrients and bioactive compounds with antioxidant and antihypercholesterolemic properties, and the RT is associated with beneficial effects on CMRF in T2DM individuals. Thus, the consumption of baru nut and the RT have potential to improve the insulin sensitivity, glycemic control, body composition, and serum lipid profile. Conclusion: The baru nut consumption and the RT have potential to reduce the cardiometabolic risk factors in T2DM. Both interventions are innovative and promising approaches to preserve the health of T2DM individuals.

scholarly journals Interleukin-15 and irisin serum concentrations are not related to cardiometabolic risk factors in patients with type 2 diabetes from Korea and Germany

2019 ◽  
Vol 57 (3) ◽  
pp. 381-384 ◽  
Author(s):  
Kyung Mook Choi ◽  
Soon Young Hwang ◽  
Kyungdo Han ◽  
Hye Soo Chung ◽  
Nam Hoon Kim ◽  
...  
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Serum Concentrations ◽  
Interleukin 15

scholarly journals Effects of Different Resistance Training Frequencies on Body Composition, Cardiometabolic Risk Factors, and Handgrip Strength in Overweight and Obese Women: A Randomized Controlled Trial

2020 ◽  
Vol 5 (3) ◽  
pp. 51
Author(s):  
Francesco Campa ◽  
Pasqualino Maietta Latessa ◽  
Gianpiero Greco ◽  
Mario Mauro ◽  
Paolo Mazzuca ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Composition ◽  
Resistance Training ◽  
Training Program ◽  
Cardiometabolic Risk ◽  
Handgrip Strength ◽  
Cardiometabolic Risk Factors ◽  
Intervention Period ◽  
Training Frequency ◽  
Weekly Frequency

Background: Resistance training improves health in obese and overweight people. However, it is not clear what is the optimal weekly resistance training frequency and the most efficacious training protocol on body composition, cardiometabolic risk factors, and handgrip strength (HS). The aim of this study was to determine the effects of a supervised structured 24 week resistance training program on obese and overweight women. Methods: Forty-five women (BMI 37.1 ± 6.3 kg/m2; age 56.5 ± 0.7 years) were randomly assigned to one of two groups: A group with a high weekly training frequency of three times a week (HIGH) and a group that performed it only once a week (LOW). Cardiometabolic risk factors, anthropometric and HS measures were taken before and after the intervention period. Results: A significant (p < 0.05) group by time interaction was observed for body weight, body mass index, waist circumference, fat mass, plasma glucose, plasma insulin, homeostatic model assessment, and for dominant and absolute HS. Additionally, only the HIGH group saw increased HS and decreased total cholesterol and LDL-cholesterol after the intervention period (p < 0.05). The observed increase in HS was associated with an improved insulin resistance sensitivity (absolute handgrip strength: r = −0.40, p = 0.007; relative handgrip strength: r = −0.47, p = 0.001) after training, which constitutes an essential element for cardiovascular health. Conclusions: The results suggest that high weekly frequency training give greater benefits for weight loss and cardiometabolic risk factors improvement than a training program with a training session of once a week. Furthermore, the improvement of HS can be achieved with a high weekly frequency training.

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