Digestibility and nutrient value of palmitoyl-L-lysine derivatives in weanling rats

1977 ◽  
Vol 55 (3) ◽  
pp. 434-438 ◽  
Author(s):  
Christian A. Stephens ◽  
Margaret J. Veen-Baigent ◽  
Alenka Paquet ◽  
G. Harvey Anderson
Keyword(s):  
Weight Gain ◽  
Amino Acid ◽  
Food Intake ◽  
Basal Diet ◽  
Amino Acid Mixture ◽  
The Other ◽  
Acid Mixture ◽  
Lysine Content ◽  
Nutrient Value ◽  
Weanling Rats

α-N,ε-N-Dipalmitoyl-L-lysine, α-N-monopalmitoyl-L-lysine, and ε-N-monopalmitoyl-L-lysine were compared with 18% casein and lysine HCl as sources of lysine in the diets of weanling rats. The lysine derivatives and lysine HCl were added to a basal diet containing 14.1% of an amino acid mixture with no lysine. Weight gain, food intake, plasma lysine, and urine and fecal lysine were determined. Animals fed the basal and lysine derivative diets lost weight over the 10-day study period. They had lower food intake, urine and plasma lysine content, and a higher fecal lysine content than animals fed the other diets. α-N-Monopalmitoyl-L-lysine was absorbed whereas the ε-N-monopalmitoyl-L-lysine and the α-N,ε-N-dipalmitoyl compounds were not.

Olfactory Conditioning by Association with Histidine-Free or Balanced Amino Acid Loads in Rats†

1973 ◽  
Vol 25 (3) ◽  
pp. 354-359 ◽  
Author(s):  
P. C. Simson ◽  
D. A. Booth
Keyword(s):  
Amino Acid ◽  
Food Intake ◽  
Amino Acid Mixture ◽  
Conditioned Aversion ◽  
Acid Mixture ◽  
Olfactory Conditioning ◽  
Conditioned Preference ◽  
Gastric Intubation ◽  
Protein Free Diet

An histidine-devoid but otherwise balanced amino acid mixture depressed food intake from 2 hr after its gastric intubation. It induced conditioned aversion to an odour incorporated in a protein-free diet presented for 6 h following intubation. In other rats, a balanced amino acid mixture established conditioned preference for odour presented in the same diet for 6 h following intubation. The degree of preference was considerably less than the degree of aversion.

Dissociation between plasma and brain amino acid profiles and short-term food intake in the rat

1994 ◽  
Vol 266 (5) ◽  
pp. R1675-R1686 ◽  
Author(s):  
G. H. Anderson ◽  
E. T. Li ◽  
S. P. Anthony ◽  
L. T. Ng ◽  
R. Bialik
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Food Intake ◽  
Amino Acid Mixture ◽  
Acid Mixture ◽  
Short Term ◽  
Egg Albumin ◽  
Amino Acid Profiles ◽  
Total Mixture ◽  
Brain Amino Acid

The relationship between plasma and brain amino acids and short-term food intake after administration of albumin, or its constituent amino acids, was examined. Rats given protein (0.85 g chicken egg albumin) or an amino acid mixture patterned after egg albumin reduced their food intake during 1 h of feeding beginning 30 min after gavage. Similarly, when given separately, the essential (EAA) and nonessential amino acid (NEAA) fractions of egg albumin caused comparable decreases in food intake. As the dose increased from 0.5 to 1.5 g the duration of anorexia prolonged to 12 h. Little change occurred in plasma amino acids at 30 and 60 min after albumin at 0.85 g, although many increased by 25-50% at 60 min after 1.5 g. Marked changes in plasma occurred after gavage with the total mixture of constituent free amino acids and after either EAA or NEAA fractions. Brain amino acid concentrations were little affected by albumin and did not show consistent changes after the amino acid treatments. Thus the reductions in food intake after ingestion of albumin or of its constituent amino acids were not predicted from the resulting changes in either plasma or brain concentrations of amino acids.

scholarly journals EFFECT OF HYDROCHLORIDE-FREE AMINO ACID MIXTURE ON GROWTH AND FOOD INTAKE IN RATS

1974 ◽  
Vol 20 (6) ◽  
pp. 431-436
Author(s):  
Hiroshi ITOH ◽  
Tetsuya KISHI ◽  
Masahiro EMA ◽  
Ichiro CHIBATA
Keyword(s):  
Amino Acid ◽  
Food Intake ◽  
Free Amino Acid ◽  
Free Amino ◽  
Amino Acid Mixture ◽  
Acid Mixture

scholarly journals Intestinal absorption of calcium in rats given diets containing casein or amino acid mixture: the role of casein phosphopeptides

1983 ◽  
Vol 49 (1) ◽  
pp. 67-76 ◽  
Author(s):  
Yeon Sook Lee ◽  
Tadashi Noguchi ◽  
Hiroshi Naito
Keyword(s):  
Small Intestine ◽  
Amino Acid ◽  
Calcium Absorption ◽  
Specific Effect ◽  
Basal Diet ◽  
Amino Acid Mixture ◽  
Acid Mixture ◽  
Distal Small Intestine ◽  
Casein Phosphopeptides

1. In an attempt to investigate calcium absorption in the rat during the postprandial period, with the least alteration of the physical environment, the undisturbed small intestine was ligated in situ 2·5 or 3·0 h after ingestion of a diet containing 200 g casein/kg or an equivalent amino acid mixture, or 925 g casein/kg. Estimation of Ca absorption was made by comparing the amount of soluble 40Ca or 45Ca in the contents of segments from the rats receiving 45Ca by intubation 30 min after withdrawal of food, ligated after a further 30 min, then killed after 0 or 30 min.2. Under conditions such that the estimated amount of a marker, polyethylene glycol, in segments ligated in a defined position was little changed in rats killed 30 min apart, the difference in the amount of soluble 40Ca was much higher in the rats fed on the basal diet containing 200 g casein/kg than in other groups.3. This specific effect on Ca absorption, particularly in the distal portion of the small intestine, could be seen also after 45Ca was directly injected into ligated segments in situ. The amount of 45Ca in the portal blood 15 min after injection of the label was also highest in the rats given the basal diet.4. The results were in agreement with our previous findings that the formation and accumulation of casein phosphopeptides causes an increase in the amount of soluble Ca in the distal small intestine.

Effect of amino acid imbalance on food intake and preference

1962 ◽  
Vol 202 (1) ◽  
pp. 165-170 ◽  
Author(s):  
Juan C. Sanahuja ◽  
Alfred E. Harper
Keyword(s):  
Amino Acid ◽  
Food Intake ◽  
Food Preference ◽  
Food Selection ◽  
Amino Acid Mixture ◽  
Acid Mixture ◽  
Balanced Diet ◽  
Amino Acid Imbalance ◽  
Ad Libitum ◽  
Protein Free Diet

Effects of an amino acid imbalance, caused by adding 3.8% of an amino acid mixture lacking histidine to a diet containing 6% of beef fibrin, on the food intake and food preference of protein-depleted rats are described. After being depleted, animals fed the balanced or imbalanced diets ate equal amounts for 3 days, then both growth rate and food intake of those fed the imbalanced diet dropped. When protein-depleted rats were fed the balanced or imbalanced diet together with a protein-free diet, neither group ate the protein-free diet during the first 3 days. Thereafter, animals fed the imbalanced diet began to eat the protein-free diet in preference to the imbalanced diet, even though the latter would support growth and the former would not. Animals fed ad libitum the balanced diet or the imbalanced diet plus histidine did not eat the protein-free diet at all. These observations indicate that both food intake and food selection are influenced by the amino acid pattern of the diet.

TrophAmine

PEDIATRICS ◽  
1988 ◽  
Vol 82 (3) ◽  
pp. 388-389
Author(s):  
STANLEY H. ZLOTKIN
Keyword(s):  
Weight Gain ◽  
Birth Weight ◽  
Amino Acid ◽  
Low Birth Weight ◽  
Nitrogen Retention ◽  
Amino Acid Mixture ◽  
Acid Mixture ◽  
Acid Solutions ◽  
Low Birth Weight Infants ◽  
Amino Acid Solutions

To the Editor.— Heird et al1 recently described the use of a new parenteral amino acid mixture for low birth weight infants which included a peptide of tyrosine (N-acetyl-l-tyrosine). They concluded that infants tolerated the new mixture well and stated that it was "more efficacious with respect to nitrogen retention and weight gain than other available mixtures." It is my contention that their results do not substantiate their claims. First, the efficiency of nitrogen retention with TrophAmine (70% retention) is not superior to older amino acid solutions.

scholarly journals Nutritional evaluation of the protein of dried tomato pomace in the rat

1976 ◽  
Vol 36 (3) ◽  
pp. 449-456 ◽  
Author(s):  
N. J. Drouliscos
Keyword(s):  
Amino Acid ◽  
Amino Acid Mixture ◽  
Acid Mixture ◽  
Nutritional Evaluation ◽  
Tomato Pomace ◽  
Weanling Rats ◽  
Bean Meal ◽  
Growth Promoting ◽  
Soya Bean Meal ◽  
Net Protein

1. Nutritional evaluation of dried tomato pomace (DTP-20) as a source of protein was carried out using weanling rats. Comparisons were made with casein (CS), soya-bean meal (SOM-45) and the hydrocarbon-grown yeast Toprina (BP-T). The growth-promoting effects of the diets were evaluated over a period of 28 d ofad lib.feeding.2. The unsupplemented DPT-20 had a protein efficiency ratio (per) of 2.18±0.13 and a net protein utilization (npu) of 0.55. The addition ofdlmethionine (5 g/kg) resulted in aperof 1.74±0.15 (t2.99,P< 0.01) and anpuof 0.40, while the addition of an amino acid mixture resulted in aperof 2.33±0.08 (t1.84,P< 0.1) and anpuof 0.70.3. The reason for the decrease in growth and the reducedperandnpuvalues recorded for the methionine-supplemented group of rats is not clear and it is discussed in connexion with an imbalance or a slight toxicity caused by the added amino acid.

Effect of energy source or fibre level in concentrates fed to finishing Swaledale lambs

2002 ◽  
Vol 2002 ◽  
pp. 121-121
Author(s):  
C A Middlemass ◽  
C M Minter ◽  
M Marsden
Keyword(s):  
Energy Source ◽  
Weight Gain ◽  
Food Intake ◽  
Live Weight ◽  
Basal Diet ◽  
The Other ◽  
Secondary Infections ◽  
Selection Of ◽  
Voluntary Food Intake ◽  
Effective Growth

Concentrate finishing systems for store lambs often involves a dramatic change in the basal diet as lambs are moved from being managed on, e.g. grass and / or roots to concentrates. If this is done too quickly there is a risk of digestive disturbances leading to acidosis and secondary infections. Hence, the selection of the carbohydrate balance between starch and digestible fibre is crucial as ruminants fed high levels of starch-based concentrates can develop sub-clinical acidosis and liver abscess, leading to decreased voluntary food intake and daily live weight gain (DLWG). The aim of this study was to evaluate two concentrate formulations for effective growth for finishing of Swaledale lambs, one concentrate being starch biased the other digestible fibre biased.

scholarly journals Histidine requirement of kittens for growth, haematopoiesis and prevention of cataracts

1987 ◽  
Vol 58 (3) ◽  
pp. 521-532 ◽  
Author(s):  
Darcy D. Quam ◽  
James G. Morris ◽  
Quinton R. Rogers
Keyword(s):  
Weight Gain ◽  
Amino Acid ◽  
Food Intake ◽  
Nitrogen Retention ◽  
The Other ◽  
Daily Weight Gain ◽  
Blood Samples ◽  
Asymptotic Values ◽  
Hb Concentration ◽  
To Receive

1. The histidine requirement of growing kittens was determined from an experiment in which forty-eight kittens were randomly allocated to six amino acid-based diets supplying: 1.0, 1.5, 2.0, 2.5, 3.0 or 4.5 g histidine base/kg diet.2. By 48 d it was obvious that 1.0 and 1.5 g histidine/kg diet were grossly inadequate so the kittens receiving these two diets were removed from the experiment. The other four groups of kittens continued to receive their diets for a total of 128 d.3. Mean daily weight gain, nitrogen retention and food intake attained plateau values at 2.1 g histidine/kg diet.4. Blood samples taken at 25 and 48 d after kittens were given the diets showed a significant effect of dietary histidine on haemoglobin (Hb) concentration. Hb and packed cell volume (PCV) attained asymptotic values at 3.0 g histidine/kg diet at 48 d. At 128 d, kittens consuming diets containing 2.0–4.5 g histidine/kg had similar Hb and PCV values.5. Cataracts of both eyes were observed in two of nine female kittens which had received diets containing either 2.0 or 2.5 g histidine/kg.6. A concentration of 3 g histidine/kg diet is recommended as a practical guide for feeding kittens.7. There was a rectilinear relation (r2 0.99) between the logarithm of the histidine concentration of plasma and the concentrationof histidine in the diet over the range 1.5–3.0 g histidine/kg diet.

Comparative Effects of Casein and Amino Acid Mixture Simulating Casein on Growth and Food Intake in Rats

1973 ◽  
Vol 103 (12) ◽  
pp. 1709-1715 ◽  
Author(s):  
Hiroshi Itoh ◽  
Tesuya Kishi ◽  
Ichiro Chibata
Keyword(s):  
Amino Acid ◽  
Food Intake ◽  
Amino Acid Mixture ◽  
Acid Mixture
Sign in / Sign up

Export Citation Format

Share Document