Responses of adult newts (Amphibia: Urodele) to x rays

1974 ◽  
Vol 52 (6) ◽  
pp. 665-669 ◽  
Author(s):  
F. T. Algard ◽  
G. B. Friedmann ◽  
H. M. McCurdy
Keyword(s):  
Active Phase ◽  
X Rays ◽  
Taricha Granulosa ◽  
Post Irradiation ◽  
Inactive Phase

Adult Taricha granulosa are relatively radioresistant in both their active (summer and spring) and inactive (winter) phases. Animals exposed to doses between 2700 and 3600 rads in their inactive phase died between 80 and 107 days post irradiation. Animals irradiated with similar doses in their active phase died between 40 and 75 days post irradiation. Some observations relating to changes in pigmentation are discussed.

scholarly journals Effect of a Neuropeptide Gene on Behavioral States in Caenorhabditis elegans Egg-Laying

Genetics ◽  
2000 ◽  
Vol 154 (3) ◽  
pp. 1181-1192 ◽  
Author(s):  
Laura E Waggoner ◽  
Laura Anne Hardaker ◽  
Steven Golik ◽  
William R Schafer
Keyword(s):  
Caenorhabditis Elegans ◽  
Active Phase ◽  
Egg Laying ◽  
Sensory Cues ◽  
Nematode Caenorhabditis Elegans ◽  
Inactive State ◽  
Recessive Mutations ◽  
Inactive Phase ◽  
Behavioral States ◽  
Stimulation Of

Abstract Egg-laying behavior in the nematode Caenorhabditis elegans involves fluctuation between alternative behavioral states: an inactive state, during which eggs are retained in the uterus, and an active state, during which eggs are laid in bursts. We have found that the flp-1 gene, which encodes a group of structurally related neuropeptides, functions specifically to promote the switch from the inactive to the active egg-laying state. Recessive mutations in flp-1 caused a significant increase in the duration of the inactive phase, yet egg-laying within the active phase was normal. This pattern resembled that previously observed in mutants defective in the biosynthesis of serotonin, a neuromodulator implicated in induction of the active phase. Although flp-1 mutants were sensitive to stimulation of egg-laying by serotonin, the magnitude of their serotonin response was abnormally low. Thus, the flp-1-encoded peptides and serotonin function most likely function in concert to facilitate the onset of the active egg-laying phase. Interestingly, we observed that flp-1 is necessary for animals to down-regulate their rate of egg-laying in the absence of food. Because flp-1 is known to be expressed in interneurons that are postsynaptic to a variety of chemosensory cells, the FLP-1 peptides may function to regulate the activity of the egg-laying circuitry in response to sensory cues.

scholarly journals Social relationships among captive male pygmy slow lorises (Nycticebus pygmaeus): Is forming male same-sex pairs a feasible management strategy?

2020 ◽  
Author(s):  
Yumi Yamanashi ◽  
Kei Nemoto ◽  
Josue Alejandro
Keyword(s):  
Social Relationships ◽  
Management Strategy ◽  
Active Phase ◽  
Same Sex ◽  
Slow Loris ◽  
The Social ◽  
Feasible Option ◽  
Inactive Phase ◽  
High Level ◽  
Social Management

Little is known about the social behavior of pygmy slow lorises, in particular, the social relationships of same sex individuals have rarely been investigated. The Slow Loris Conservation Centre was built at the Japan Monkey Centre to enhance the welfare of confiscated slow lorises, promote their conservation, improve public education and perform scientific research on the species. In the course of improving housing conditions, several same-sex pairs of pygmy slow lorises were formed. We monitored their behaviors and fecal glucocorticoid metabolite (FGM) levels to understand whether male same sex pairings could be a feasible management strategy. The subjects were 10 male and 6 female lorises for comparison, all of whom were over five years old. We successfully formed five pairs of male lorises after eight formation attempts. Male pairs initially showed some aggressive behaviors; however, the rate decreased approximately 10 days after introduction. All of the male pairs eventually exhibited extensive affiliative social behaviors, including allogrooming and social play, during the dark (active) phase, and sleep site sharing during the light (inactive) phase. The rate of sleep site sharing during the light phase was higher than expected, suggesting that the pairs preferred to stay near each other. There was no evidence of increased stress after a long period of male male social housing. Female same sex pairs and male female pairs demonstrated a high level of affiliative behaviors right after introduction. These results highlight the flexibility and high sociability of this species and indicate that such same sex pairings are a feasible option for their social management.

The synthetic activity of primordial germ cells in normal and irradiated neonatal male rats

Development ◽  
1968 ◽  
Vol 19 (2) ◽  
pp. 239-249
Author(s):  
I. C. Lett
Keyword(s):  
Germ Cells ◽  
Primordial Germ Cells ◽  
Giant Cells ◽  
Male Rats ◽  
Synthetic Activity ◽  
X Rays ◽  
Short Term ◽  
Post Irradiation ◽  
Histological Appearance ◽  
Transitional Cells

Resting primordial germ cells or gonocytes, present in the testis of the rat at birth (Beaumont & Mandl, 1963), are highly radiosensitive. A dose of 50–100 r X-rays induces complete, or almost complete, sterility, as judged by the histological appearance of the testis at 25 days post parturn (Mandl et al. 1964). Studies of short-term post-irradiation changes have revealed that gonocytes, exposed to a sterilizing dose of X-rays at birth, do not degenerate immediately after exposure but differentiate normally into transitional cells (the immediate precursors of definitive germ cells; Beaumont & Mandl, 1963; Huckins, 1963; Franchi & Mandl, 1964) so that no histological abnormalities are detectable for 5 or 6 days. Subsequently, however, the irradiated transitional cells fail to divide; they increase markedly in size and form irregularly shaped giant cells which eventually become pyknotic (Franchi & Mandl, 1966; see also Sapsford, 1965a).

Adaptive Motion and Force Control of Robots Performing a Complete Task

1999 ◽  
Author(s):  
Prabhakar R. Pagilla ◽  
Biao Yu
Keyword(s):  
Force Control ◽  
Position Control ◽  
Active Phase ◽  
Free Motion ◽  
Constrained Motion ◽  
Control Laws ◽  
Adaptive Motion ◽  
Inactive Phase ◽  
The Impact ◽  
Three Phases

Abstract In this work, we consider adaptive motion and force control of a robot performing a complete task. By a complete task we mean that the robot desired task contains both free motion and constrained motion. Further, we also consider transition from free motion to constrained motion. We divide the motion of the robot into three phases: (i) inactive phase, where the robot is in free motion, (ii) transition phase, where the transition from free motion to constrained motion takes place, and (iii) active phase, where the robot is in constrained motion with simultaneous force and position control. Uncertainty of the constraint results in the impact of robot with the constraint surface when transition from free motion to constrained motion. We design stable control laws for the three phases that results in an efficient algorithm for robots performing a complete task. Extensive experiments are conducted to show the validity of the proposed control designs.

Paget Disease

2019 ◽  
pp. 14-18
Author(s):  
Peter J. Haar
Keyword(s):  
Older Patients ◽  
Pathologic Fracture ◽  
Active Phase ◽  
Cortical Thickening ◽  
Cross Sectional ◽  
Paget Disease ◽  
Cross Sectional Imaging ◽  
Inactive Phase ◽  
Focal Zone ◽  
Sarcomatous Degeneration

Chapter 73 discusses Paget disease, which is a progressive bone disease of excessive bone turnover and abnormal, disordered bone remodeling. Paget disease generally affects older patients. Paget disease has an initial active phase with a focal zone of osteolysis and an inactive phase with bone enlargement, trabecular coarsening, and cortical thickening. The diagnosis of Paget disease is usually made with radiographs, though cross-sectional imaging can be useful for early diagnosis in the skull and spine. Rare complications of Paget disease include neural impingement and sarcomatous degeneration. Treatment is provided with medical therapy and surgical treatment of pathologic fracture or prophylactic fixation.

scholarly journals Time matters: pathological effects of repeated psychosocial stress during the active, but not inactive, phase of male mice

2012 ◽  
Vol 215 (3) ◽  
pp. 425-437 ◽  
Author(s):  
Manuela S Bartlang ◽  
Inga D Neumann ◽  
David A Slattery ◽  
Nicole Uschold-Schmidt ◽  
Dominik Kraus ◽  
...  
Keyword(s):  
Social Preference ◽  
Active Phase ◽  
Time Of Day ◽  
Dark Phase ◽  
Light Phase ◽  
Immunological Parameters ◽  
Repeated Restraint Stress ◽  
Inactive Phase ◽  
Home Cage Activity

Recent findings in rats indicated that the physiological consequences of repeated restraint stress are dependent on the time of day of stressor exposure. To investigate whether this is also true for clinically more relevant psychosocial stressors and whether repeated stressor exposure during the light phase or dark phase is more detrimental for an organism, we exposed male C57BL/6 mice to social defeat (SD) across 19 days either in the light phase between Zeitgeber time (ZT)1 and ZT3 (SDL mice) or in the dark phase between ZT13 and ZT15 (SDD mice). While SDL mice showed a prolonged increase in adrenal weight and an attenuated adrenal responsiveness to ACTHin vitroafter stressor termination, SDD mice showed reduced dark phase home-cage activity on observation days 7, 14, and 20, flattening of the diurnal corticosterone rhythm, lack of social preference, and higherin vitroIFNγ secretion from mesenteric lymph node cells on day 20/21. Furthermore, the colitis-aggravating effect of SD was more pronounced in SDD than SDL mice following dextran sulfate sodium treatment. In conclusion, the present findings demonstrate that repeated SD effects on behavior, physiology, and immunology strongly depend on the time of day of stressor exposure. Whereas physiological parameters were more affected by SD during the light/inactive phase of mice, behavioral and immunological parameters were more affected by SD during the dark phase. Our results imply that repeated daily SD exposure has a more negative outcome when applied during the dark/active phase. By contrast, the minor physiological changes seen in SDL mice might represent beneficial adaptations preventing the formation of those maladaptive consequences.

scholarly journals Convective activities associated with intraseasonal variation over Sumatera, Indonesia, observed with the equatorial atmosphere radar

2004 ◽  
Vol 22 (11) ◽  
pp. 3899-3916 ◽  
Author(s):  
T. H. Seto ◽  
M. K. Yamamoto ◽  
H. Hashiguchi ◽  
S. Fukao
Keyword(s):  
Indian Ocean ◽  
Active Phase ◽  
Western Pacific ◽  
Mountainous Area ◽  
Local Circulation ◽  
Intraseasonal Variation ◽  
Cloud Clusters ◽  
Inactive Phase ◽  
The Indian Ocean ◽  
The Western Pacific

Abstract. The influence of intraseasonal variation (ISV) on convective activities over Sumatera (or Sumatra) is studied by using data derived from the Equatorial Atmosphere Radar (EAR), the Boundary Layer Radar (BLR), the surface weather station, the Geostationary Meteorological Satellite (GMS), and NCEP/NCAR reanalysis. In June 2002, convective activities over the Indian Ocean, the maritime continent, and the western Pacific were significantly modulated by the ISV. Blackbody brightness temperature observed by GMS (TBB) showed that two super cloud clusters (SCCs) developed over the Indian Ocean (70-90° E) in the first half of June 2002, and propagated eastward from the Indian Ocean to the western Pacific. Convective activities were enhanced over the western Pacific (130-160° E) in the latter half of June 2002. Convergence at 1000hPa, which prevailed over the Indian Ocean in the first half of June 2002, propagated eastward to the western Pacific in the latter half of June 2002. Zonal wind observed by EAR and surface pressure observed at the observation site suggested the existence of a Kelvin-wave-like structure of ISV. From temporal variations of TBB, zonal wind at 850hPa, and vertical shear of horizontal wind between 700 and 150hPa, we classified the observation periods into the inactive phase (1-9 June), active phase (10-19 June), and postwesterly wind burst phase of ISV (20-26 June). During the inactive phase of ISV, convective activities caused by local circulation were prominent over Sumatera. Results of radar observations indicated the dominance of convective rainfall events over the mountainous area of Sumatera during the inactive phase of ISV. During the active phase of the ISV, cloud clusters (CCs), which developed in the convective envelope of SCC with a period of 1-2 days, mainly induced the formation of convective activities over Sumatera. Results of radar observations indicated that both convective and stratiform rainfall events occurred over the mountainous area of Sumatera during the active phase of ISV. In the postwesterly wind burst phase of ISV, convective activities were suppressed over Sumatera. Features of convective activities found over Sumatera generally agreed well with those found in Tropical Ocean and Global Atmosphere/Coupled Ocean-Atmosphere Response Experiment (TOGA COARE). However, local circulation played an important role in the formation of convective activities over Sumatera in the inactive phase of ISV.

Reproductive phase dependent variation in lung-associated immune system (LAIS) and expression of melatonin receptors (Mel1a and Mel1b) in the lung of the Jungle-Bush Quail (Perdicula asiatica)

2011 ◽  
Vol 89 (1) ◽  
pp. 10-18 ◽  
Author(s):  
R. K. Kharwar ◽  
C. Haldar
Keyword(s):  
Immune System ◽  
Significant Variation ◽  
Active Phase ◽  
Melatonin Receptors ◽  
Melatonin Receptor ◽  
Reproductive Phase ◽  
Inactive Phase ◽  
Avian Lung ◽  
Circulatory Level ◽  
Reproductive Phases

The present study was performed to assess the variation of the lung-associated immune system (LAIS) in the Jungle-Bush Quail ( Perdicula asiatica (Latham, 1790)) during two different reproductive phases when differences in the circulatory level of hormones (melatonin and gonadal steroid) and environmental conditions were maximum. We noted high significant variation in size and number of bronchus-associated lymphoid tissue (BALT) nodules, as well as in the size and number of non-BALT nodules, during the reproductively inactive phase (RIP; December) compared with the active phase (RAP; June). We also noted high significant variation in the percent stimulation ratio of lung lymphocyte, as well as in the concentrations of plasma melatonin and melatonin receptors, during RIP compared with RAP. Testosterone level and number of macrophages in lungs were high during RAP. Thus, we suggest that the LAIS had reproductive phase dependent variation, which could be due to (i) variation in environmental factors (photoperiod, temperature, and humidity) and (ii) circulatory level of hormones (melatonin and testosterone). Because of the importance of melatonin in avian immune regulation, we assess and document the expression of melatonin receptor types Mel1a and Mel1b in the avian lung, which suggest that the lung is a target organ for melatonin and that melatonin is an immunomodulator for lung-associated immunity in birds.

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