Effects of Moxibustion on Cellular Immunocomptence of γ-Irradiated Mice

1989 ◽  
Vol 17 (03n04) ◽  
pp. 157-163 ◽  
Author(s):  
Dou-Mong Hau ◽  
Jing-Chong Wu ◽  
Yung-Hsien Chang ◽  
Jen-Tzw Hwang
Keyword(s):  
Inhibitory Effect ◽  
The Body ◽  
Lymphoid Cells ◽  
Whole Body ◽  
Control Group ◽  
Thymidine Uptake ◽  
Γ Irradiation ◽  
Group A ◽  
Γ Ray ◽  
Group B

The effects of moxibustion on cellular immunocompetence of γ-irradiated mice were investigated in this study. A total of 240 male young mice (ICR strain), 6–8 weeks of age, were chosen and divided into three groups. Group A was the normal control. Group B, the experimental control, was treated with 400 rad whole body γ-irradiation. Group C, the experimental group, was treated with moxibustion (MT) after being exposed to γ-irradiation. Six to eight mice from each group were sacrified on days 1, 5, 12, 19, 26 and 33 post-irradiation. The body and splenic weights of mice in each group were measured. The cellular immunocompetence was measured by 3H-thymidine uptake in each experimental mouse. The results revealed that 400 rad of γ-ray irridiation inhibited the increase of body and splenic weights, and exerted a pronounced inhibitory effect on the incorporative rates of 3H-thymidine after being stimulated by mitogens such as PHA, PWM, Con A and LPS in the splenic lymphoid cells. MT seemed to help the recovery of the cellular immunocompetence in the γ-ray irradiated mice.

Effects of Ganoderma Lucidum and Krestin on Subset T-cell in Spleen of γ-irradiated Mice

1995 ◽  
Vol 23 (03n04) ◽  
pp. 289-298 ◽  
Author(s):  
Wang-Chi Chen ◽  
Dou-Mong Hau ◽  
Chih-Chung Wang ◽  
I-Hsin Lin ◽  
Shiuh-Sheng Lee
Keyword(s):  
Body Weight ◽  
Ganoderma Lucidum ◽  
Radiation Treatment ◽  
Whole Body ◽  
Control Group ◽  
Γ Irradiation ◽  
Group A ◽  
Group B ◽  
Group D ◽  
Better Than

Effects of Ganoderma lucidum (Gl) and Krestin (PSK) extracts on spleen, thymus and splenocytes in γ-irradiated mice were investigated in this study. ICR strain male mice were divided into five groups. Group A was the normal control. Group B, the experimental control, was treated with Gl. Group C, the radiation treatment control, was treated with whole body exposure to 4 Gy γ-irradiation (RT). Group D was treated with RT and Gl. Group E was treated with RT and PSK. The dosage of Gl was 400 mg/day/kg body weight and PSK was 500 mg/day/kg body weight. Our results indicated that the relative thymus weight in groups D and E were higher than group C on day 28 after γ-irradiation. Group D was the highest in all the experimental groups. CD4 and CD8 splenocytes in group D were higher than group C on days 7 and 28. Gl was better than PSK in repairing the damage of subset T-cells in the spleen of γ-irradiated mice.

Effects of Kuei-Pi-Tang on Cellular Immunocompetence of γ-Irradiated Mice

1993 ◽  
Vol 21 (02) ◽  
pp. 151-158 ◽  
Author(s):  
Hsue-yin Hsu ◽  
Dou-mong Hau ◽  
Chun-ching Lin
Keyword(s):  
Thymidine Incorporation ◽  
Inhibitory Effect ◽  
The Body ◽  
Lymphoid Cells ◽  
Whole Body ◽  
Therapeutic Effects ◽  
Radiation Injuries ◽  
Male Mice ◽  
Splenic Cells ◽  
Γ Ray

Kuei-Pi-Tang is a kind of traditional Chinese medicine which has been suggested to have therapeutic effects on hemato-deficient disease and radiation injuries. In order to further investigate its protection function, this study is focused on the efficacy of Kuei-Pi-Tang on cellular immunocompetence of γ-ray irradiated mice. ICR strain male mice were chosen and divided into several groups for their different treatments of 4 Gy γ-ray whole body irradiation and Kuei-Pi-Tang administration. After the treatments, six to eight mice from each group were sacrificed on days 1, 5, 12, 19, 26 and 33. The body and splenic weights of mice by different treatments were measured and the splenic cells separated thereafter. The changes of cellular immunocompetence in mice following treatments were measured by 3H-thymidine incorporation. The results revealed that 4 Gy of γ-ray irradiation inhibits the increases of body and splenic weights and exerts a pronounced inhibitory effect on the incorporative rates of 3H-thymidine in the splenic lymphoid cells which have been stimulated by mitogens. Kuei-Pi-Tang administration seems to increase the recovery of the cellular immunocompetence, especially for the treatment of Kuei-Pi-Tang administered with the concentration of 20 mg/20 g body weight after γ-ray irradiation.

scholarly journals Protocol on Comparative Clinical Efficacy of Tryushanadi Guggul and Navaka Guggul in Sthoulya (Overweight)

2021 ◽  
pp. 169-175
Author(s):  
Ashvini Dineshrao Pardhekar ◽  
Sadhana Misar(Wajpeyi) ◽  
Vinod Ade
Keyword(s):  
Clinical Efficacy ◽  
The Body ◽  
Control Group ◽  
Arm Circumference ◽  
Before And After ◽  
Group A ◽  
Excessive Intake ◽  
Group B ◽  
Excessive Accumulation

Background: Sthoulya is Medovaha Strotodushtijanya vyadhi, which includes abnormal and excessive accumulation of Medodhatu in the body. This is caused by lack of physical and mental activity, daytime sleep, excessive intake of madhur (sweet), snigdha ahar (oily diet) results in  increase Kaphadosha and meda which results in Sthoulya (overweight) having symptoms of mild dysponea, thirst, drowsiness, excess sleep, appetite, offensive smell from the body, incapability to work and incapability to participate in sexual intercourse. Aim: Comparative clinical efficacy of Tryushanadi Guggul and Navaka Guggul in Sthoulya (overweight). Materials and methods: Total 60 patients of Sthoulya will enrolled and will divided into two groups (each group contains 30). Patients in group A (experimental group) will be given 1 gram Tryushanadi Guggul two times a day after meal with honey and in group B (control group)1 gram Navaka Guggul will administered two times a day after meal with honey for 30 days. Dietary changes and walking (30 minutes) will be advised to patients of both groups. Follow up will be taken on 15th day and 30th day. Assessment of subjective parameters like kshudrashwasa (exertional dyspnoea), swedadhikya (perspiration), atikshudha (increased appetite), nidradhikya (increased sleep) and objective parameters like body weight, B.M.I., mid arm circumference, waist-hip ratio and lipid profile will be done before and after treatment. Results: Subjective and objectives outcomes will be assessed by statistical analysis. Conclusion: It will be drawn from the result obtained.

scholarly journals A Study to Compare Effect of Hold-Relax v/s Static Stretching on Elbow Flexors Muscle Spasticity in Stroke - A Comparative Study

2021 ◽  
Vol 11 (7) ◽  
pp. 309-313
Author(s):  
Dafda Renuka H ◽  
Shah Shreya R
Keyword(s):  
Functional Independence ◽  
The Body ◽  
Control Group ◽  
Elbow Flexors ◽  
Static Stretching ◽  
Muscle Spasticity ◽  
Modified Ashworth Scale ◽  
Before And After ◽  
Group A ◽  
Group B

Background: Stroke is a condition in which Spasticity in the body musculature greatly affect the functional independence of the patients. Hold- Relax and Static Stretching is one of the useful treatment to reduce Spasticity. Aim: To find out the effect of Hold – Relax V/S Static Stretching on Elbow flexors muscle Spasticity in Stroke Patient Materials and Methods: 20 subjects were randomly allocated into two groups (Group A and Group B). For 10 subjects in Group A Control group was given Static Stretching with conventional rehab and Group B Experimental group was given Hold- Relax with conventional rehab. Treatment were given to 3 weeks 3 sets per sessions. The outcome measure used to assess the Spasticity before and after the intervention was Modified Ashworth Scale (MAS). Results and Discussion: The Hold-Relax group showed a significant reduction in Spasticity of Elbow flexors muscle, compared to the control group (p<0.05). Conclusions: Hold- Relax is more effective than Static Stretching. Key words: Stroke, Spasticity, Hold- Relax, Static Stretching, MAS.

scholarly journals Lower weight gain after vaping cessation than after smoking quitting

2019 ◽  
pp. 253-258
Author(s):  
Ewelina Wawryk-Gawda ◽  
Michał K. Zarobkiewicz ◽  
Patrycja Chylińska-Wrzos ◽  
Barbara Jodłowska-Jędrych
Keyword(s):  
Weight Gain ◽  
Electronic Cigarettes ◽  
Mass Gain ◽  
The Body ◽  
Control Group ◽  
Prior History ◽  
History Of ◽  
Group A ◽  
Lower Weight Gain ◽  
Group B

Background. Smoking is frequently a way to control appetite and weight. The data concerning the body mass gain after quitting among the users of electronic cigarettes who have no prior history of smoking traditional cigarettes is inconsistent. Objective. In our study we have compared smoking and vaping impact on weight gain and glycaemia. Material and methods. 3 groups of rats were used. The group A was exposed to vapour and group B were exposed to smoke. Rats in the group C constituted the control group without nicotine exposition. Results. During 6 weeks of experiment weight gain of rats in the A and B groups was comparable, while animals from group C had gained signifi0cantly more. During 2 weeks after cessation of exposition to nicotine animals from group B gained more weight than rats of A and C group. Blood glucose was higher in group B than in groups A and C 24 h after last exposure to nicotine and 2 weeks after nicotine exposure cessation. Conclusion. Effects of vaping on weight increase is similar to smoking, but after vaping cassation weight gain is lower and comparable with nicotine nonusers.

scholarly journals CELECOXIB

2018 ◽  
Vol 25 (01) ◽  
pp. 50-57
Author(s):  
Sadia Sundus ◽  
Nazia Qamar ◽  
Raheela Adil ◽  
Muhammad Faisal Fahim
Keyword(s):  
Body Weight ◽  
Relative Weight ◽  
Treated Group ◽  
Renal Tissue ◽  
The Body ◽  
Control Group ◽  
Albino Rats ◽  
Group A ◽  
Group B ◽  
General Architecture

Objective: To observe the absolute, relative weight of kidney and body weightof albino rats on celecoxib induced kidney with protection by lycopene. Study Design:Experimental study. Place and Duration of study: This study was conducted in BMSI (Anatomydepartment), JPMC, Karachi, from 4th May 2015 to 3rd June 2015. Materials and Methods: Fortyhealthy adult, male Albino rats, 90-120 days old, weighing 200-220gm was taken for the study.The rats were divided into 4 groups, Group A was control group, Group B receive Celecoxib 50mg/kg body weight orally, Group C receive Celecoxib 50 mg/kg body weight orally along withlycopene50 mg/kg body weight orally and Group D receive lycopene 50 mg/kg body weightorally for 30 days. At the end of study rats were sacrificed and renal tissue sections were stainedwith hematoxylin and eosin. Results: Markedly decreased weight was observed in rats takingcelecoxib. Slides which were stained with hematoxylin and eosinshowed general architecture ofrenal parenchyma, shape and arrangement of epithelial cells. Apoptosis, hemorrhage, necrosisand vacuolation seen in Celecoxib group, whereas renal architecture were ameliorated andreverted back in celecoxib along with lycopene receiving group. Conclusion: This studyconcludes that lycopene restored the body weight, absolute and relative kidney weight incelecoxib treated group.

scholarly journals Effects of Moringa oleifera on the developing cerebrum of young wistar rats

1970 ◽  
Vol 8 (1) ◽  
Author(s):  
A Z Abijo ◽  
O O Adeeyo ◽  
O A Komolafe ◽  
O S Saka ◽  
V K Abodunrin
Keyword(s):  
Frontal Cortex ◽  
Wistar Rats ◽  
Moringa Oleifera ◽  
The Body ◽  
Brain Weight ◽  
Control Group ◽  
Significant Difference ◽  
Group A ◽  
High Doses ◽  
Group B

The study evaluated the effects of moringa oleifeira on the histoarchitecture of the cerebral cortex, the body weight and brain weight of young wistar rats. Fifteen (15) young wistar rats of both sexes weighing 20-30g were used for this study. They were randomly assigned into three groups (A, B and C) of five rats each. Group A served as control and received distilled water, group B and C received 100 mg/kg and 200mg/kg of moringa oleifera respectively. Treatment lasted for a period of 6 weeks (orally). Rats were weighed and sacrificed under ketamine (30 mg/kg) anaesthesia. The cerebrum was harvested and fixed immediately in 10% formolcalcium, for further histological processing. One-way ANOVA was used to analyze data, followed by Newan-Keuls (SNK) for multiple comparisons. The results showed that there was significant increase in the feed intake of animals in groups B and C starting from the 4th week of administration. There was no significant difference in the relative brain weight and the mean weight of the rats in group B and C when compared with group A. Histological findings revealed that there was slight distortion in group B and more distortion in group C when compared with the normal histoarchitecture in control group A. The results obtained from this study showed that high doses of Moringa oleifera caused damage of some parts of histoarchitecture of the frontal cortex of developing wistarKey words: MORINGA OLEIFERA; Cerebrum; Frontal Cortex

scholarly journals Effect of epidural analgesia on the duration of labour and pains: a comparative study

2020 ◽  
Vol 9 (4) ◽  
pp. 1451
Author(s):  
Pallavi Chauhan ◽  
S. D. Shirodkar
Keyword(s):  
Pain Relief ◽  
Epidural Analgesia ◽  
New Technologies ◽  
Active Phase ◽  
The Body ◽  
Control Group ◽  
Second Stage Of Labour ◽  
Significant Difference ◽  
Group A ◽  
Group B

Background: Epidural analgesia is regional anaesthesia that blocks pain in a particular region of the body. The use of Epidural Analgesia (EA) in labor is widespread in modern labor ward practice, and its benefits in terms of pain relief are well-recognized. Objective of this study was to study the effect of epidural analgesia on the duration of labour and pains.Methods: The present study was conducted on 60 women in the department of obstetrics and gynecology at Topiwala National Medical College, Mumbai during a period from October 2014 to January 2017. The women requesting EA were assigned as the study group (Group A - 30 cases) and women not receiving EA were included in the control group (Group B - 30 cases).Results: The duration of active phase of first and second stage of labour was found to be prolonged in patients who received EA as compared to control group. An increase in number of caesarean sections and requirement of oxytocin augmentation was found to be more in Group A as compared to Group B. There was no statistically significant difference in Apgar score of newborns at 1 min and 5 min in both the groups. The patients demanding epidural drug had better pain relief during labour. In Group A, 17% of patients and in Group B, 7% of patients had nausea and vomiting. Other side effects were minimal.Conclusions: Epidural analgesia is not a totally free of disadvantages, it is the most effective mode of pain relief available compared with other techniques. The addition of patient-controlled epidural analgesia and innovations using new technologies enhance patient satisfaction.

scholarly journals Effects of probiotics and enzymes on growth performance and haematobiochemical parameters in broilers

2014 ◽  
Vol 11 (1) ◽  
pp. 111-118 ◽  
Author(s):  
MS Rahman ◽  
A Mustari ◽  
M Salauddin ◽  
MM Rahman
Keyword(s):  
Growth Performance ◽  
The Body ◽  
Control Group ◽  
Broiler Chicks ◽  
Erythrocyte Sedimentation ◽  
Group A ◽  
Group B ◽  
Hb Concentration ◽  
Group D ◽  
Poultry Farming

An study was conducted on "Cobb-500" broiler chicks to evaluate the effects of probiotics and enzymes supplementation on growth performance, haematological and biochemical parameters. A total of 20, fourteen days old broiler chicks were divided randomly into four groups using five broiler chicks in each group. Group A was designated as control group was given only normal broiler ration and rest of the groups were fed probiotics and enzymes, [Group B (probiotic Microguard® @ 1 gm/L), Group C (enzymes preparation Acmezyme* 1 gm/L), Group D (Microguard* g 1 gm/L and Acmezyme @ 1 gm/L)] with drinking water respectively from 1St to 21st day of study. It was observed that probiotics and enzymes supplementation enhanced the body growth rate. At the final day of experiment the body weight was significantly increased (P<0.01) in the treated groups in comparison with that of control group. Total Erythrocyte Count (TEC), Hemoglobin (Hb) concentration, Packed Cell Volume (PCV) were significantly increased (p<0.01) in treated groups than the control group. Erythrocyte Sedimentation Rate (ESR) and Serum alanine aminotransaminase (ALT) levels were decreased significantly (p<0.01) than the control group. The serum Serum aspertate aminotransaminase (AST) level was decreased significantly (p<0.01) in all treated groups except group D than the control group. It is suggests that the poultry farming may be benefited using probiotics and enzymes. DOI: http://dx.doi.org/10.3329/jbau.v11i1.18221 J. Bangladesh Agril. Univ. 11(1): 111-118, 2013

Effects of Ganoderma Lucidum and Krestin on Cellular Immunocompetence in γ-Ray-irradiated Mice

1995 ◽  
Vol 23 (01) ◽  
pp. 71-80 ◽  
Author(s):  
Wang-Chi Chen ◽  
Dou-Mong Hau ◽  
Shiuh-Sheng Lee
Keyword(s):  
Body Weight ◽  
Ganoderma Lucidum ◽  
Radiation Treatment ◽  
Whole Body ◽  
Control Group ◽  
Con A ◽  
Γ Irradiation ◽  
Leukocyte Counts ◽  
Γ Ray ◽  
Group D

The effects of Ganoderma lucidum (Gl) and Krestin (PSK) extracts on cellular immunocompetence, leukocyte counts and differential count in γ-irradiated mice were investigated in this study. ICR strain male mice were used and randomly divided into five groups. Group A is normal control. Group B, the experimental control, was treated with Gl. Group C, the radiation treatment control, was treated with whole body exposure to 4 Gy γ-irradiation (RT). Group D was treated with RT and Gl. Group E was treated with RT and PSK. The dosage of Gl was 400 mg/day/kg body weight and PSK was 500 mg/day/kg body weight. After irradiation, six mice from each group were sacrificed on day 7 and the other six on day 28. Cellular immunocompetence was measured by means of 3 H -thymidine incorporation with splenic cells stimulated through mitogens such as PHA, Con A and LPS. The results revealed that relative splenic weight in Groups D and E were higher than group C on day 28 after γ-irradiation, Group D was the highest in all the experimental groups. Leukocyte counts were decreased significantly in Groups D and E on day 7, the former was a little higher than the latter. Gl administration showed an increase in the leukocyte count in Group D on day 28. The blastogenic response of splenocytes to PHA and Con A in groups D and E were higher than in Group C on days 7 and 28. We suggested that Gl and PSK were effective in enhancing the recovery of cellular immunocompetence from γ-ray irradiation.

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