BioBoard

2007 ◽  
Vol 11 (05) ◽  
pp. 259-267
Keyword(s):  
South Korea ◽  
Brain Research ◽  
Basic Research ◽  
Hiv Infections ◽  
Breast Cancer Patients ◽  
Bird Flu ◽  
Polio Vaccine ◽  
Set Up ◽  
Hep B ◽  
Start Ups

Australia — Australian Scientists Discover a Treatment for Malaria. Australia — Australian of the Year Wins Science Medal. Australia — Industry Researchers Receives Prestigious Awards. Australia — Australia Supports Biotech Start-ups. Australia — Phylogica Receives Funding for Brain Research. China — Enshi Pharma Wins Top Honors. China — Nutra Pharma to Start HIV Drug Production in China. China — CAS, INSERM and Wuhan University to Set Up a Hepatopathy Institute. China — Novartis to Launch Hep B Drug in China. China — China's Top 10 Advances in Basic Research in 2006. China — Local Researchers Rake in 42 National Science Awards. China — China Invited to Join Global Fight Against Disease. China — GlaxoSmithKline to Build Research Center in China. China — China and France to Jointly Develop Traditional Chinese Medicine. India — India Shows a Decline in Number of AIDS Sufferers. India — India and Norway Collaborate on Vaccination Research. India — India Launches Polio Vaccine Drive. India — Agilent Earmarks US$35 Million for India. Indonesia — Vaccine May Treat Many Bird Flu Strains. Malaysia — Malaysian Scientists Develop Herbal Drug for Dengue. New Zealand — New Trans-Tasman Bioscience Pact. Singapore — Scientists Discover Risk Gene in Breast Cancer Patients. Singapore — Ciba to Build Antioxidant Plant in Singapore. South Korea — South Korea Culls 35,000 Ducks in Latest Bird Flu Outbreak. Taiwan — Taiwan Biotech Output Valued at Over US$5.36 Billion. Taiwan — Scientists Plan China, Hong Kong, Taiwan Stem Cell Trial. Taiwan — Taiwan Government Revamps Pharma Regulations. Vietnam — Bird Flu Resurfaces in Southern Vietnam. Others — Asia to Fight Tuberculosis and HIV Infections.

BioBoard

2007 ◽  
Vol 11 (04) ◽  
pp. 203-211
Keyword(s):  
South Korea ◽  
Human Sperm ◽  
Quality Of Healthcare ◽  
High Achievers ◽  
Bird Flu ◽  
Research Activities ◽  
Innovation Fund ◽  
Medical Program ◽  
Bio Imaging ◽  
Set Up

Australia — The Number of Biotech Jobs in Australia Increases. Australia — Scientists Invent New Parkinson's Disease Diagnostic Test. Australia — Two Australian High Achievers Honored. Australia — A*STAR's Institute of Microelectronics (IME), Australian-based BioChip Innovations and Singapore-based SiMEMS Team Up for Biochip Research. Australia — QUT Develops HIV Nanofilters. China — CAS Declares its Notion of Science. China — China Bans Illegal Trade in Human Sperm and Eggs. China — Guangdong On Alert against SARS. China — Nationwide Medical Program Halted after Device Found Unreliable. China — US National Stem Cell Team Travels to China for Collaborations. China — Rabies—A Top Killer in East China. China — Six People Tried in Shanghai for Pirating Tamiflu. China — Chinese Authorities Release HIV/AIDS Advocate. China — CEO of WuXi PharmaTech, Dr Ge Li Wins Top Science Award. Hong Kong — New Discoveries on Bird Flu Virus. India — CIPI Collaborates with CPMA. India — Deakin University to Set Up Institute for Research in Biotech, Nanotech in India. India — ICMR Launches Medical Innovation Fund. Indonesia — Indonesia to Prepare for Measles Vaccination Drive. Indonesia — Indonesia Agrees to Share Bird Flu Samples. Indonesia — Indonesia's Dengue Death Toll Rises. Philippines — Female Rice Researcher Wins International Award. Singapore — Singapore to Focus on Quality of Healthcare. Singapore — GleneaglesCRC Opens New Offices in Australia, South Korea and Indonesia. Singapore — Israel and Singapore Team Up on Research Activities. Singapore — Workshop for Life Science Held in Singapore. Singapore — Kuwait Finance Ties Up with Singapore Firm to Set Up Medical Centers. Singapore — A*STAR Invests $10 million to Focus on Bio-Imaging and Immunology. South Korea — Scientists Develop Medicinal Supplements using Carbon Dioxide. South Korea — South Korea's to Increase its National R&D Budget. Taiwan — TaiGen Appoints Dr Luke Lin as VP of Clinical Research and Development. Others — WHO Reports Promising Results on Avian Influenza Vaccines.

Bioboard

2008 ◽  
Vol 12 (08) ◽  
pp. 5-17
Keyword(s):  
South Korea ◽  
Local Governments ◽  
Tamil Nadu ◽  
Joint Venture ◽  
The Philippines ◽  
Treatment Center ◽  
Bird Flu ◽  
Flu Vaccine ◽  
Biomedical Electronics ◽  
Set Up

AUSTRALIA — New Meningococcal Test to Identify Genetic Predisposition AUSTRALIA — Scientists Discover the Double Life of Proteins AUSTRALIA — Gene Discovery Offers Cancer Hope CHINA — The American Psychiatric Association's Awards for Young Scientists Encourage Research Expertise in China CHINA — DuPont Partners with China to Increase Farm Productivity CHINA — Deadly Enterovirus Afflicts Chinese Children CHINA — CAS Researchers Decode Genome of Mosquito-Killing Bacterium CHINA — CAS, Local Governments to Jointly Set Up a Biomedical Institute in Suzhou CHINA — Chinese and US Scientists Map Papaya Genes CHINA — Genzyme to Build New R&D Center in Beijing INDIA — Avesthagen Launches Bioactive Teestar INDIA — Scientists Find Kala-azar Protein INDIA — Bayer Launches Disease-Resistant Hybrid Rice Arize Dhani INDIA — SCHOTT Forms Pharmaceutical Joint Venture in India INDIA — IIT Mumbai Develops Chip to Detect Myocardial Infarction INDIA — Tamil Nadu Plans Poison Treatment Center in Every District INDIA — RFCL Opens Integrated Manufacturing Plant in India JAPAN — Pfizer to Launch Champix® – The First Prescription Oral Smoking Cessation Aid in the Country NEW ZEALAND — Asthma Linked to High Fat Diet PHILIPPINES — Surge in Dengue Cases in the Philippines SOUTH KOREA — Bird Flu Outbreaks Spread in South Korea SINGAPORE — Edwards Lifesciences Opens Its First Heart Valve Manufacturing Facility in Singapore SINGAPORE — Bioimaging and Stem Cell Research in Singapore gets a Million Dollar Boost from Latest Grant Calls by A*STAR SINGAPORE — Maccine Receives Bio-Industry Award for Best Preclinical or Clinical CRO in Asia TAIWAN — New Group for Biomedical Electronics Established TAIWAN — Stroke Evaluation Indicator Discovered VIETNAM — Vietnam Bird Flu Vaccine Returns Positive Results

BioBoard

2007 ◽  
Vol 11 (11) ◽  
pp. 680-688
Keyword(s):  
New Zealand ◽  
South Korea ◽  
Cervical Screening ◽  
Drug Market ◽  
Tax Incentives ◽  
Patent Litigation ◽  
Tight Control ◽  
Bird Flu ◽  
Set Up ◽  
Cervical Cancer Vaccine

Australia — Glaxo Cervical Cancer Vaccine Approved in Australia. Australia — Ten Million Dollar Grant to Establish Australian Mammalian Cell Production Facility. Australia — AgResearch and CSIRO Plant Industry Collaborate. China — Bird Flu Continues to be Public a Health Threat in China. China — China to Regularly Probe Drug Market. China — China and Cuba Set Up Joint Biotech Venture. China — GlaxoSmithKline to Set up a Drug Research Center in China. China — China Commited to Control the Spread of HIV. China — China Implements Tight Control Ordered over Assisted Reproductive Technology. India — OPPI to Adopt Marketing Code for Medicines. Indonesia — Indonesia Says US Critics Helped Push WHO to Change Virus-Sharing System. Indonesia — Indonesia Hands Out Kits to Fight Bird Flu. Japan — Kobe Team Succeeds in Mass Cultivation of Stem Cells. Malaysia — Bird Flu in Selangor "Confined to Three Villages". Malaysia — Polartechnics' Cervical Screening System Goes to Malaysia. New Zealand — Ryman Donates US$120 000 to Medical Research. New Zealand — New Zealand Establishes First Private Radiotherapy Center in Auckland. New Zealand — New Zealand Offers R&D Tax Incentives. Singapore — Singapore Steps up Fight against Dengue. South Korea — Korea Opens First Proton Radiotherapy Center. South Korea — Korean Yuyu Inc Files Patent Litigation against Merck. South Korea — South Korea Slaughters Thousands of Pigs to Stem Spread of Bird Flu. Thailand — Cancer — Next Priority in Pharma War. Thailand — Population and Community Development Association (PDA) of Thailand Receives 2007 Gates Award. Thailand — Eisai Seeks Thailand's Approval for Gasmotin. Vietnam — Bird Flu Survivors' Antibodies Effective.

BioBoard

2007 ◽  
Vol 11 (03) ◽  
pp. 129-138
Keyword(s):  
South Korea ◽  
Generic Drugs ◽  
Cancer Therapeutics ◽  
Cooperative Research ◽  
Indian Government ◽  
Bird Flu ◽  
Cooperative Research Center ◽  
Flu Vaccine ◽  
Set Up ◽  
National Disaster

Australia — New Cooperative Research Center for Cancer Therapeutics in Melbourne. Australia — WEHI Collaborates with Genentech to Develop New Cancer Drugs. Australia — Australia Prepares to Vaccinate its Entire Population Against Bird Flu. China — China Revokes Licenses of 160 Drug Firms. China — Three More National Laboratories to be Set up at CAS. China — Covance Expands Operations in China. China — CAS Launches a New Round of Academician Selection with Strict Procedures. China — China Slashes Cost of Overpriced Drugs. China — New Diabetic Drug Manufactured in Shanghai. Japan — Japan Confirms 32nd Mad Cow Case. Japan — New Bird Flu Outbreak Suspected in Japan. Indonesia — Indonesia to Declare Bird Flu a National Disaster. Indonesia — Baxter Collaborates with the Indonesian Government. Indonesia — Indonesia Develops a Bird Flu Vaccine. India — India to Carry Out First Multi-centric Clinical Trial with Stem Cells. India — Lotus Labs and Labindia Team Up to Build a Clinical Research Academy. India — Bangalore to Build Knowledge City. India — Indian Companies to Bid for Merck's Generics Business. India — India and Croatia Pledge One million Euros for Scientific Research. India — India to Lead in Global Stem Cell Market by 2010. India — Biotech Leaders Receive Indian Government Awards. Malaysia — Malaysia Opens a New Laboratory for Hazardous Disease Research. Philippines — Philippines Bans Imports of Live Birds and Poultry from Japan. Singapore — Singapore Keeping up Vigilance Against Infectious Diseases. Singapore — Singapore Health Ministry Considering Legislation on Biomedical Research. Singapore — TNT Appoints Onno Boots as South East Asia's Regional Managing Director. South Korea — South Korea Aims to Become Top 10 Science Nation by 2010. Taiwan — Taiwan Works on Bird Flu Vaccine. Taiwan — Taiwan Introduces World's First DNA chip. Thailand — Bird Flu Strikes in Thailand Again. Thailand — Thai Pharma Industry Against Thai Government's Decision to Produce Generic Drugs.

BioBoard

2006 ◽  
Vol 10 (23) ◽  
pp. 1325-1332
Keyword(s):  
Hong Kong ◽  
South Korea ◽  
Research Work ◽  
Compulsory License ◽  
Indian Government ◽  
Cell Bank ◽  
Bird Flu ◽  
Joint Construction ◽  
Set Up ◽  
Botanical Medicine

Australia — Australia Ends Ban on Embryo Cloning for Research. Australia — Australia Government Allocates A$500 million for Science. Australia — Gardasil Immunization Program in Australia from Next Year. China — AIDS Patients to be Compensated for Blood Infection. China — New AIDS Therapy More Effective. China — Changzhou National Hi-Tech District Creates Alliance with Samara Province in Russia For Joint Construction Of Science & Technology Park. Hong Kong — New CRO in Hong Kong to Feed China. Hong Kong — Botanical Medicine Company Chi-Med Collaborates with Merck. India — Indian Pharmaceuticals Agree to Supply Cheaper Drugs for Children with AIDS. India — British Pharmacopoeia Officials to Hold Talks with Indian officials. India — Indian Government to Set Up Five Institutes to Boost Pharma R&D. South Korea — South Korea Reports on its Second Outbreak of Bird Flu. Singapore — Scientists will Perform Research Work on New Stem Cell Bank. Singapore — Scientists Discover New Path for Malaria Drug. Singapore — Singapore's Fusionopolis Phase 2A Sells Out. Singapore — Singapore Ministries to Tackle Rise in AIDS Number. Singapore — A*STAR-Karolinska Symposium on Immunology. Singapore — Singapore to Set Up Two Biomed R&D Centers. Singapore — Human Embroynic Stem Cells Research in Singapore. Thailand — Thai Health Ministry To Issue Compulsory License For Merck's HIV/AIDS Drug Efavirenz. Others — Gardisil Research in Britain. Others — World Bank Says More Funding Needed to Fight Bird Flu.

scholarly journals Optimization of a WGA-Free Molecular Tagging-Based NGS Protocol for CTCs Mutational Profiling

2020 ◽  
Vol 21 (12) ◽  
pp. 4364
Author(s):  
Giuseppa De Luca ◽  
Barbara Cardinali ◽  
Lucia Del Mastro ◽  
Sonia Lastraioli ◽  
Franca Carli ◽  
...  
Keyword(s):  
Substantial Reduction ◽  
Breast Cancer Patients ◽  
Dna Templates ◽  
Molecular Tagging ◽  
Mutational Profiling ◽  
Optimized Protocol ◽  
Set Up ◽  
Detection Of Mutations ◽  
Almost All ◽  
Next Generation Sequencing Ngs

Molecular characterization of Circulating Tumor Cells (CTCs) is still challenging, despite attempts to minimize the drawbacks of Whole Genome Amplification (WGA). In this paper, we propose a Next-Generation Sequencing (NGS) optimized protocol based on molecular tagging technology, in order to detect CTCs mutations while skipping the WGA step. MDA-MB-231 and MCF-7 cell lines, as well as leukocytes, were sorted into pools (2–5 cells) using a DEPArray™ system and were employed to set up the overall NGS procedure. A substantial reduction of reagent volume for the preparation of libraries was performed, in order to fit the limited DNA templates directly derived from cell lysates. Known variants in TP53, KRAS, and PIK3CA genes were detected in almost all the cell line pools (35/37 pools, 94.6%). No additional alterations, other than those which were expected, were found in all tested pools and no mutations were detected in leukocytes. The translational value of the optimized NGS workflow is confirmed by sequencing CTCs pools isolated from eight breast cancer patients and through the successful detection of variants. In conclusion, this study shows that the proposed NGS molecular tagging approach is technically feasible and, compared to traditional NGS approaches, has the advantage of filtering out the artifacts generated during library amplification, allowing for the reliable detection of mutations and, thus, making it highly promising for clinical use.

BioBoard

2006 ◽  
Vol 10 (22) ◽  
pp. 1267-1273
Keyword(s):  
Hong Kong ◽  
New Zealand ◽  
South Korea ◽  
Drug Approval ◽  
Influenza Virus Vaccine ◽  
Biomedical Ethics ◽  
Bird Flu ◽  
H5n1 Avian Influenza Virus ◽  
H5n1 Avian Influenza ◽  
Speed Up

Australia — Politicians Chastise Australia's Science Institute. Australia — GE Healthcare and WA Government Collaborate on Cell-based Imaging Equipment. Australia — The Goal of Imugene's H5N1 Avian Influenza Virus Vaccine. China — East China University Sparks Debate on Education Funding. China — 3D Map of SARS virus Drawn. China — Researchers Comment that Global Loss of Biodiversity is Harming Ocean Bounty. China — China Insists that there are No Variant Bird Flu Strain. China — Gene involved in Eye Lens Development. China — Cancer-causing Dye Found in Duck Eggs in China. Hong Kong — Scientists in Hong Kong Found Clues to Pandemic Bird Flu. Hong Kong — Hong Kong Bird Flu Expert Picked to Head WHO. India — Ranbaxy Signs Licensing Agreement with Swiss Company Debiopharm. India — Indian Biotechnology Park. Japan — Japan's New Premier Chases Innovation. Japan — Japan Reforms Screening to Speed up Drug Approval. New Zealand — New Zealand Invests in Neurology Project. South Korea — South Korea Gives Funding Boost to Stem-Cell Research. South Korea — South Korea Plans to Inject $253 million into Biotech. South Korea — Scientists Discover Stem Cells Might Help to Treat Mental Illness. Singapore — Renowned French Cancer Development Biologist Moves to Singapore's Biopolis. Singapore — Singapore Plans to Build Bigger Heart Center to Handle Spiraling Patient Numbers. Singapore — New Centre for Biomedical Ethics at NUS. Taiwan — Taiwan's CDC Places Order for H5N1 Vaccine. Taiwan — Tenders sought for Pingtung Agricultural Biotech Park Housing.

U.S.S.R. to Set Up Fund for Basic Research

Science ◽  
1988 ◽  
Vol 242 (4875) ◽  
pp. 23-23
Author(s):  
David Dickson
Keyword(s):  
Basic Research ◽  
Set Up

scholarly journals Use of Germline Genetic Variability for Prediction of Chemoresistance and Prognosis of Breast Cancer Patients

Cancers ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 511 ◽  
Author(s):  
Viktor Hlavac ◽  
Maria Kovacova ◽  
Katerina Elsnerova ◽  
Veronika Brynychova ◽  
Renata Kozevnikovova ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Disease Free Survival ◽  
Breast Cancer Patients ◽  
Cytotoxic Therapy ◽  
Free Survival ◽  
Testing Phase ◽  
Major Allele Frequency ◽  
Set Up ◽  
Disease Free

The aim of our study was to set up a panel for targeted sequencing of chemoresistance genes and the main transcription factors driving their expression and to evaluate their predictive and prognostic value in breast cancer patients. Coding and regulatory regions of 509 genes, selected from PharmGKB and Phenopedia, were sequenced using massive parallel sequencing in blood DNA from 105 breast cancer patients in the testing phase. In total, 18,245 variants were identified of which 2565 were novel variants (without rs number in dbSNP build 150) in the testing phase. Variants with major allele frequency over 0.05 were further prioritized for validation phase based on a newly developed decision tree. Using emerging in silico tools and pharmacogenomic databases for functional predictions and associations with response to cytotoxic therapy or disease-free survival of patients, 55 putative variants were identified and used for validation in 805 patients with clinical follow up using KASPTM technology. In conclusion, associations of rs2227291, rs2293194, and rs4376673 (located in ATP7A, KCNAB1, and DFFB genes, respectively) with response to neoadjuvant cytotoxic therapy and rs1801160 in DPYD with disease-free survival of patients treated with cytotoxic drugs were validated and should be further functionally characterized.

scholarly journals An observational study of post-operative Volumetric Modulated Arc Radiotherapy (VMAT) of breast cancer by immobilizing patients on All-in-one (AIOTM) solution Breast and Lung Board without usingthermoplastic mask: Risk of collusion of gantry with couch exists if acquisition of Cone-beam Computed Tomography (CBCT)is attempted for set-up verification.

2020 ◽  
Author(s):  
Ramaiah Vinay Kumar
Keyword(s):  
Breast Cancer ◽  
Computed Tomography ◽  
Cancer Patients ◽  
Target Volume ◽  
Cone Beam ◽  
Breast Cancer Patients ◽  
Unilateral Breast Cancer ◽  
Planar Image ◽  
X Ray ◽  
Set Up

Abstract Background: Automatic Cone-beam computed tomography (CBCT) based image matching for set-up verification is recommended as compared to 2-D match for post-operative local / loco-regional radiotherapy of breast cancer patients by Volumetric Modulated Arc Therapy (VMAT) technique. However, in supine position, off-midline peripheral body Clinical Target Volume (CTV) of unilateral breast cancer patients immobilized on Breast and Lung board of All-in-One (AIO) positioning systemmay necessitate augmented movement of couch in ‘x’ and ‘z’ axis thereby raising the risk of collusion of x-ray sources / detectors system with couch. Methods and Materials: VMAT was planned by a pair of partial arc for whole target volume for seven consecutive post-operative breast cancer patients (five post-mastectomy and two post-breast conservation patients). Tattoo based set-up by shift of treatment table in x-, y- and z-axis as determined by Treatment Planning System followed by X-rays with planar image acquisition and online 2-D imaging matching was performed for set-up verification. In-room 360°rotation of x-ray source and detector system of linear accelerator (linac) was performed before x-ray planar image acquisition. Results: Completion of 360°rotation in-room of x-ray source and detector system of linacaround the machine iso-centre was not possible in six out of seven patients due to possibility of collusion of gantry with contralateral side of the couch. Conclusion: Performing CBCT for generating 3D images for computed tomography (CT) reconstruction may not be practical for patient set-up verification of post-operative radiotherapy of unilateral breast cancer patients positioned supine on breast and lung board.

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