The emergence of Web 2.0 and its rapid adoption by the corporate world, known as Enterprise 2.0, has radically modified access to tacit knowledge and significantly reduced business latency. Meanwhile, technology for wireless LAN and mobile communication, combined with advances in handsets, has allowed for superior quality of experience with acceptable productivity level. Combining mobility with Enterprise 2.0 is the next big step in evolution. This article presents the drivers for Enterprise 2.0 and the challenge of tapping tacit knowledge and, in parallel, the evolution of wireless and mobile technologies. The era of mobile broadband life is made possible, creating new ways of use and expectations for Millennials. The next business generation will be able to unleash the full potential of mobility and Enterprise 2.0. Three scenarios selected from different vertical domains—healthcare, education and emergency services—illustrate the benefits of mobility and Enterprise 2.0 in action. With the expected continued strong growth of wireless access, mobility support is one, if not the, key success factor for Enterprise 2.0.