Factors Influencing Survival of Rats in Fasting

1957 ◽  
Vol 188 (2) ◽  
pp. 332-336 ◽  
Author(s):  
R. H. Rixon ◽  
J. A. F. Stevenson

The individual duration of survival of adult rats in complete fasting varied considerably; the range at an environmental temperature of 22°C was 6–16 days, at 2–5°C, 1–7 days, and in thyroidectomized animals at 22°C, 15–25 days. This variation in survival was not closely related to the initial body weight but was related to the individual proportionate body weight loss per day and the total proportionate weight loss sustained before death. The individual proportionate rate of weight loss has been correlated with the metabolic rate indicating that the former reflected the metabolic rate of the animal. The duration of survival in fasting has been correlated with the individual metabolic rate, whether measured before or during fasting. Since fasting did not obliterate or reduce the individual differences in metabolic rate, it was possible to predict the individual duration of survival from knowledge of the prefasting metabolic rate. The total proportionate weight loss, which also influenced the survival time in fasting, was altered by changes in the environmental temperature and probably by other factors. The previous diet whether high in protein, fat or carbohydrate had little effect on the duration of survival. Fasting caused a decrease in the metabolic rate of intact rats at 22°C but no change in that of thyroidectomized rats or of rats living in the cold.

1968 ◽  
Vol 8 (35) ◽  
pp. 668 ◽  
Author(s):  
JG Morris

Groups of Hereford heifers of a mean (� SE.) body weight 187 � 3 kg were fed in yards a sole ration of sorghum grain + one per cent limestone for 26 weeks. Four groups were fed the equivalent of 1.36 kg of sorghum grain per head per day as either whole or cracked grain at either daily or twice weekly intervals. A fifth group was fed 1.64 kg of whole sorghum grain per head per day which provided a digestible dry matter intake comparable to that of 1.36 kg of cracked grain. When heifers were fed the same quantity of dry matter as whole and cracked grain, the rate of body weight loss of those fed whole grain was significantly greater than that of those fed cracked grain; and the rate of body weight loss of those fed daily was significantly greater than that of those fed twice weekly. With similar intakes of digestible dry matter from whole and cracked grain, there was no significant difference in the rate of body weight loss. Heifers from sub-groups of high initial body weight lost significantly more body weight than heifers from sub-groups of low initial body weight. The whole bodies of three heifers that died from undernutrition contained less than 0.3 per cent ether extract on a fresh weight basis, indicating complete exhaustion of body energy reserves.


2002 ◽  
Vol 56 (6) ◽  
pp. 551-556 ◽  
Author(s):  
E Bobbioni-Harsch ◽  
O Huber ◽  
Ph Morel ◽  
G Chassot ◽  
T Lehmann ◽  
...  

2020 ◽  
Vol 101 (5) ◽  
pp. 669-676
Author(s):  
T I Omarov ◽  
N Yu Bayramov ◽  
M R Huseynova ◽  
N A Zeynalov

Aim. To study of the effect of the diameter of the calibration tube and the distance from the pyloric sphincter on the outcomes of the laparoscopic sleeve gastrectomy. Methods. The study included 945 (915 women) patients with a body mass index 51.59 kg/m2. The average age of the patients was 53.58.5 years. The patients were divided into 2 groups by the type of laparoscopic surgery: in the first group (n=463), a 36 Fr calibration tube was used, the distance from the pyloric sphincter was 46 cm; in the second group (n=482), a 32 Fr calibration tube was used, the distance from the pyloric sphincter was 23 cm. The main comparison criteria was the percentage of body weight loss in the first 6 and 12 months, and an additional comparison criteria was the of concomitant diseases progress in postoperative and the existence of complications. Results. A comparative analysis showed that the first group in the first 6 months lost 593% of its initial body weight, while in 12 months 714%; in the second group, 733 and 873% of the initial weight, respectively. Concomitant diseases in the first group decreased by 7080% by the 6th month after surgery and by 8596% by the 12th month. In the 2nd group, similar remission with improvement was between 84 and 94% at the 6th month, and remained the same at the 12th month. Conclusion. The results of the study show that in laparoscopic sleeve gastrectomy with a calibration tube diameter 32 Fr and a distance of 23 cm from the pyloric sphincter, compared to a calibration tube diameter 36 Fr or more and a distance of 46 cm from the pyloric sphincter, a body weight loss faster and more effective with earlier remission of concomitant diseases, while the number of complications is comparable.


1964 ◽  
Vol 19 (5) ◽  
pp. 863-867 ◽  
Author(s):  
Arthur M. Kodama ◽  
Nello Pace

Body fat content and the melting point and fatty acid composition of body fat of hamsters exposed to 35, 27, 20, 15, 10, and 6 C for 2 weeks were determined. The relationship between exposure temperature and body fat content and composition resembled that between environmental temperature and metabolic rate. Below the critical temperature, there was a progressive decrease in total body fat content and melting point accompanied by a decrease in the mole fraction of palmitic acid and an increase in the mole fraction of oleic acid. The softening of body fat in cold-exposed animals appears to be the result of an increased mobilization of depot fat in response to a higher metabolic rate in the cold, a mobilization which is at least partially selective with respect to individual fatty acids or triglycerides. Examination of changes in whole body composition revealed that 72% of the loss in body weight of hamsters exposed to 6 C was due to a decrease in body fat content. In contrast, the decrease in body fat content accounted for only 28% of the body weight loss of pair-fed hamsters kept at 27 C on reduced caloric intake to match the body weight loss experienced by cold-exposed animals. It appears, therefore, that cold exposure induces a more effective fat depot mobilization than does reduced caloric intake. heat exposure; cold exposure; body composition Submitted on February 3, 1964


Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1965-P
Author(s):  
TEAYOUN KIM ◽  
JESSICA P. ANTIPENKO ◽  
SHELLY NASON ◽  
NATALIE PRESEDO ◽  
WILLIAM J. VAN DER POL ◽  
...  

2018 ◽  
Vol 44 (1) ◽  
Author(s):  
Ayako Ito ◽  
Aya Nozaki ◽  
Ichiro Horie ◽  
Takao Ando ◽  
Atsushi Kawakami

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