Density dependence of respiratory system impedances between 5 and 320 Hz in humans

1989 ◽  
Vol 67 (6) ◽  
pp. 2323-2330 ◽  
Author(s):  
A. C. Jackson ◽  
C. A. Giurdanella ◽  
H. L. Dorkin

For respiratory system impedance (Zrs), the six-element model of DuBois et al. (J. Appl. Physiol. 8: 587-594, 1956) suggests three resonant frequencies (f1,f2,f3), where f1 is the result of the sum of tissue and airway inertances and tissue compliance and f2 is the result of alveolar gas compression compliance (Cg) and tissue inertance (Iti). Three such resonant frequencies have been reported in humans. However, the parameter estimates resulting from fitting this model to the data suggested that f2 and f3 were not associated with Cg and Iti but with airway acoustic properties. In the present study, we measured Zrs between 5 and 320 Hz in 10 healthy adult humans breathing room air or 80% He-20% O2 (HeO2) to gain insight as to whether airway or tissue properties are responsible for the f2 and f3. When the subjects breathed room air, f2 occurred at 170 +/- 16 (SD) Hz, and when they breathed HeO2 it occurred at 240 +/- 24 Hz. If this resonance were due to Cg and Iti it should not have been affected to this extent by the breathing of HeO2. We thus conclude that f2 is not due to tissue elements but that it is an airway acoustic resonance. Furthermore, application of the six-element model to analyze Zrs data at these frequencies is inappropriate, and models incorporating the airway acoustic properties should be used. One such model is based on the concept of equivalent length, which is defined as the length of an open-ended, cylindrical tube that has the same fundamental acoustic resonant frequency.(ABSTRACT TRUNCATED AT 250 WORDS)

1987 ◽  
Vol 62 (2) ◽  
pp. 414-420 ◽  
Author(s):  
A. C. Jackson ◽  
K. R. Lutchen

Mechanical impedances between 4 and 64 Hz of the respiratory system in dogs have been reported (A.C. Jackson et al. J. Appl. Physiol. 57: 34–39, 1984) previously by this laboratory. It was observed that resistance (the real part of impedance) decreased slightly with frequency between 4 and 22 Hz then increased considerably with frequency above 22 Hz. In the current study, these impedance data were analyzed using nonlinear regression analysis incorporating several different lumped linear element models. The five-element model of Eyles and Pimmel (IEEE Trans. Biomed. Eng. 28: 313–317, 1981) could only fit data where resistance decreased with frequency. However, when the model was applied to these data the returned parameter estimates were not physiologically realistic. Over the entire frequency range, a significantly improved fit was obtained with the six-element model of DuBois et al. (J. Appl. Physiol. 8: 587–594, 1956), since it could follow the predominate frequency-dependent characteristic that was the increase in resistance. The resulting parameter estimates suggested that the shunt compliance represents alveolar gas compressibility, the central branch represents airways, and the peripheral branch represents lung and chest wall tissues. This six-element model could not fit, with the same set of parameter values, both the frequency-dependent decrease in Rrs and the frequency-dependent increase in resistance. A nine-element model recently proposed by Peslin et al. (J. Appl. Physiol. 39: 523–534, 1975) was capable of fitting both the frequency-dependent decrease and the frequency-dependent increase in resistance. However, the data only between 4 and 64 Hz was not sufficient to consistently determine unique values for all nine parameters.


1991 ◽  
Vol 70 (3) ◽  
pp. 1051-1058 ◽  
Author(s):  
A. C. Jackson ◽  
K. R. Lutchen

The lumped six-element model of the respiratory system proposed by DuBois et al. (J. Appl. Physiol. 8: 587-594, 1956) has often been used to analyze respiratory system impedance (Zrs) data. This model predicts a resonance (relative minimum in Zrs) at fr between 6 and 10 Hz and an antiresonance (relative maximum in Zrs) at far at higher frequencies (greater than 64 Hz). The far is due to the lumped tissue inertance (Iti) and the alveolar gas compression compliance (Cg). An fr and far have been recently reported in humans, but the far was shown to be not related to Iti and Cg, but instead it is the first acoustic antiresonance of the airways due to their axial dimensions). Zrs data to frequencies high enough to include the far have not been reported in dogs. In this study, we measured Zrs in dogs for frequencies between 5 and 320 Hz and found an fr at 7.5 +/- 1.6 Hz and two far at 97 +/- 13 and 231 +/- 27 Hz (far,1 and far,2, respectively). When breathing 80% He-20% O2, the fr shifted to 14 +/- 2 Hz, far,1 did not change (98 +/- 9 Hz), and far,2 increased to greater than 320 Hz. The behavior of fr and far,1 is consistent with the structure-function implied by the six-element model. However, the presence of an far,2 is not consistent with this model, because it is the airway acoustic antiresonance not represented in the model. These results indicate that, for frequencies that include the fr and far,1, the six-element model can be used to analyze Zrs data and reliable estimates of the model's parameters can be extracted by fitting the model to the data. However, more complex models must be used to analyze Zrs data that include far,2.


1990 ◽  
Vol 68 (6) ◽  
pp. 2403-2412 ◽  
Author(s):  
K. R. Lutchen ◽  
C. A. Giurdanella ◽  
A. C. Jackson

Respiratory input impedance (Zrs) from 2.5 to 320 Hz displays a high-frequency resonance, the location of which depends on the density of the resident gas in the lungs (J. Appl. Physiol. 67: 2323-2330, 1989). A previously used six-element model has suggested that the resonance is due to alveolar gas compression (Cg) resonating with tissue inertance (Iti). However, the density dependence of the resonance indicates that is associated with the first airway acoustic resonance. The goal of this study was to determine whether unique properties for tissues and airways can be extracted from Zrs data by use of models that incorporate airway acoustic phenomena. We applied several models incorporating airway acoustics to the 2.5- to 320-Hz data from nine healthy adult humans during room air (RA) and 20% He-80% O2 (HeO2) breathing. A model consisting of a single open-ended rigid tube produced a resonance far sharper than that seen in the data. To dampen the resonance features, we used a model of multiple open-ended rigid tubes in parallel. This model fit the data very well for both RA and HeO2 but required fewer and longer tubes with HeO2. Another way to dampen the resonance was to use a single rigid tube terminated with an alveolar-tissue unit. This model also fit the data well, but the alveolar Cg estimates were far smaller than those expected based on the subject's thoracic gas volume. If Cg was fixed based on the thoracic gas volume, a large number of tubes were again required. These results along with additional simulations show that from input Zrs alone one cannot uniquely identify features indigenous to alveolar Cg or to the respiratory tissues.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ahmad H. Bokhari ◽  
Martin Berggren ◽  
Daniel Noreland ◽  
Eddie Wadbro

AbstractA subwoofer generates the lowest frequency range in loudspeaker systems. Subwoofers are used in audio systems for live concerts, movie theatres, home theatres, gaming consoles, cars, etc. During the last decades, numerical simulations have emerged as a cost- and time-efficient complement to traditional experiments in the design process of different products. The aim of this study is to reduce the computational time of simulating the average response for a given subwoofer design. To this end, we propose a hybrid 2D–3D model that reduces the computational time significantly compared to a full 3D model. The hybrid model describes the interaction between different subwoofer components as interacting modules whose acoustic properties can partly be pre-computed. This allows us to efficiently compute the performance of different subwoofer design layouts. The results of the hybrid model are validated against both a lumped element model and a full 3D model over a frequency band of interest. The hybrid model is found to be both accurate and computationally efficient.


1988 ◽  
Vol 64 (2) ◽  
pp. 823-831 ◽  
Author(s):  
H. L. Dorkin ◽  
K. R. Lutchen ◽  
A. C. Jackson

Recent studies on respiratory impedance (Zrs) have predicted that at frequencies greater than 64 Hz a second resonance will occur. Furthermore, if one intends to fit a model more complicated than the simple series combination of a resistance, inertance, and compliance to Zrs data, the only way to ensure statistically reliable parameter estimates is to include data surrounding this second resonance. An additional question, however, is whether the resulting parameters are physiologically meaningful. We obtained input impedance data from eight healthy adult humans using discrete frequency forced oscillations from 4 to 200 Hz. Three resonant frequencies were seen: 8 +/- 2, 151 +/- 10, and 182 +/- 16 Hz. A seven-parameter lumped element model provided an excellent fit to the data in all subjects. This model consists of an airway resistance (Raw), which is linearly dependent on frequency, and airway inertance separated from a tissue resistance, inertance, and compliance by a shunt compliance (Cg) thought to represent gas compressibility. Model estimates of Raw and Cg were compared with those suggested by measurement of Raw and thoracic gas volume using a plethysmograph. In all subjects the model Raw and Cg were significantly lower than and not correlated with the corresponding plethysmographic measurement. We hypothesize that the statistically reliable but physiologically inconsistent parameters are a consequence of the distorting influence of airway wall compliance and/or airway quarter-wave resonance. Such factors are not inherent to the seven-parameter model.


1984 ◽  
Vol 57 (4) ◽  
pp. 1222-1230 ◽  
Author(s):  
Andrew C. Jackson ◽  
Mehrdad Tabrizi ◽  
Michael I. Kotlikoff ◽  
Jon R. Voss

A computer model of the mechanical properties of the dog respiratory system based on the asymmetrically branching airway model of Horsfield et al. (11) is described. The peripheral ends of this airway model were terminated by a lumped-parameter impedance representing gas compression in the alveoli, and lung and chest wall tissue properties were derived from measurements made in this laboratory. Using this model we predicted the respiratory system impedance and the distribution of pressures along the airways in the dog lung. Predicted total respiratory system impedances for frequencies between 4 and 64 Hz at three lung volumes were found to compare quite closely to measured impedances in dogs. Serial pressure distributions were found to be frequency-dependent and to result in higher pressures in the lung periphery than at the airway opening at some frequencies. The implications of this fading for high-frequency ventilation are discussed. impedance; high-frequency ventilation; central airway resistance; respiratory system resistance; airway pressure distribution; distribution of ventilation Submitted on November 14, 1983 Accepted on May 8, 1984


Author(s):  
Hironori Tohmyoh

Abstract This paper presents the materials evaluation and environmental monitoring techniques utilizing the acoustic resonance, which have been developed by the authors. When the ultrasound passes through thin layer, the transmission and reflection coefficients take their maximum and the minimum values at the resonant frequency. We call this acoustic resonance. The acoustic properties of a polymer film, e.g., the acoustic impedance, ultrasonic velocity, and density, can be determined by observing the acoustic resonance, which occurs at the water/film/reflection plate interface. Acoustic resonance occurs at the reflection plate/film/outer environment interface sensitively changes depending on the outer environment. With use of this, the temperature of the water as an outer environment is tried to be monitored.


2008 ◽  
Vol 2 (2) ◽  
Author(s):  
Yingchun Zhang ◽  
Gerald W. Timm ◽  
Arthur G. Erdman

Objectives: The purpose of this study is to establish pressure, distension and other parameters involved that produce tissue injury during vigorous physical activities in women, so that superior methods and devices for diagnosing and treating urinary incontinence (UI) can be created. Background: A higher prevalence of daily UI in a female athlete population was found compared to that of a randomly selected and age matched sample population, but the mechanism of UI is not clearly understood. Methods: Mechanical tissue properties of affected organ structures were determined by using specimens from cadavers. A realistic geometric model of the female pelvis was developed from patients’ specific CT images. The finite element model was built by combining the mechanical tissue properties and the geometry of organs involved, and the finite element analysis (FEA) was then performed using ABAQUS 6.7 to simulate the biomechanical response of the female pelvis during physical activities. Results: Tissue specimens from 11 cadavers were tested which included specimens of the bladder, uterus, pelvic muscle, vagina and urethra. A finite element model was built with approximately 500,000 tetrahedral elements. The force level and resulting organ displacements in the female pelvis during physical activities were investigated successfully by using the FEA method. Discussion: The knowledge of force level and organ displacements during physical activities helps to understand the mechanisms of UI occurring during physical activities.


2020 ◽  
Vol 64 (1-4) ◽  
pp. 639-647
Author(s):  
Zhichao Cai ◽  
Zhenyong Zhao ◽  
Lan Chen ◽  
Guiyun Tian

In this paper, a new electromagnetic acoustic resonance (EMAR) transducer is proposed for precise thickness measurement in specimen. The new EMAR is composed of a mirror symmetric coil (MSC) and a pair of Nd-Fe-B permanent magnets with the different polarity for enhancing the generation and detection of resonant signals. Firstly, a finite element model was established to simulate the distributions of Lorentz force produced by new EMAR and the resonant process of shear waves. Furthermore, the relationship between the frequency response characteristic of the new EMAR and the common EMAR were explored. Finally, to verify the performance of the EMAR, several experiments were performed. Compared with the common EMAR transducer, the resonant amplitude of the new EMAR transducer was increased by 121.74% and the signal-to-noise ratio was increased by 28.35%, and the resonance frequency interval of the new EMAR was twice that of the common mode in the frequency domain simulation experiment, this advantage effectively reduced the error rate of measurement. The results show that the new EMAR transducer with mirror coil structure has higher accuracy in thickness detection of specimens.


2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Yiming Luo ◽  
Tianliang Qu ◽  
Bin Zhang ◽  
Yao Pan ◽  
Pengbo Xiao

The resonator is the key element of the Coriolis Vibratory Gyroscope (CVG). The vibrational characteristics of the resonator, including the resonant frequency, vibrational amplitude, and Q factor, have a great influence on CVG’s performance. Among them, the vibrational amplitude mainly affects the scale factor and the signal-to-noise ratio, and the Q factor directly determines the precision and drift characteristics of the gyroscope. In this paper, a finite element model of a cylindrical shell resonator actuated by piezoelectric electrodes with different thicknesses is built to investigate the vibrational characteristics. The simulation results indicate that the resonant frequency barely changes with the electrode thickness, whereas the vibrational amplitude is inversely proportional to the electrode thickness under the same driving voltage. Experiments were performed with four resonators and piezoelectric electrodes of four sizes, and results were consistent with simulations. The resonant frequencies of four resonators changed within 0.36% after attaching the piezoelectric electrodes. Meanwhile, with the same driving voltage, it was shown that the vibrational amplitude decreased with the increase of electrode thickness. Moreover, thinner electrodes resulted in better Q factor and therefore better performance. This study may provide useful reference on electrode design of the CVGs.


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