scholarly journals The Decerebrate Cat Generates the Essential Features of the Force Constraint Strategy

2010 ◽  
Vol 103 (6) ◽  
pp. 3266-3273 ◽  
Author(s):  
Claire F. Honeycutt ◽  
T. Richard Nichols

Cats actively respond to horizontal perturbations of the supporting surface according to the force constraint strategy. In this strategy, the force responses fall into two groups oriented in either rostral and medial directions or caudal and lateral directions, rather than in strict opposition to the direction of perturbation. When the distance between forelimbs and hindlimbs is decreased, the responses are less constrained and directed more in line with the perturbation. We have recently shown that electromyographic responses from limb muscles of the decerebrate cat resemble those obtained in the intact animal. Our objectives here were to determine whether the decerebrate cat preparation would also exhibit the force constraint strategy and whether that strategy would exhibit the characteristic dependence on limb position on the strategy. Horizontal support surface perturbations were delivered and three-dimensional exerted forces were recorded from all four limbs. Clustered force responses were generated by all four limbs and were found to be statistically indistinguishable between animals decerebrated using two different levels of transection. The directionality of the force responses was preserved throughout successive time epochs during the perturbations. In addition, the clustering of force responses increased with distance between forelimbs and hindlimbs. These results indicate that the force constraint strategy used by terrestrial animals to maintain stability can be generated without the assistance of the cerebral cortices and without prior training. This suggests an important role for the lower brain stem and spinal cord in generating an appropriate strategy to maintain stability.

2016 ◽  
Vol 6 (1) ◽  
pp. 194-202
Author(s):  
Петров ◽  
Aleksey Petrov ◽  
Стеновский ◽  
Viatcheslav Stenovsky ◽  
Белоусова ◽  
...  

The aim of the study is to prevent the machine´s withdrawal from the technological trajec-tory in conditions of the slope agriculture. The object of study is the process of wheel tractor´s withdrawal of a given course in the mode of operation on sloping areas of the support surface. The results of theoretical studies of the power balance in the process of interaction between the tread elements with an inclined supporting surface are given. The functional relationship of pow-er given on the tractorexchange rate stability and configurational, geometric parameters of the tread´s working elements of the wheel mover.


2009 ◽  
Vol 101 (6) ◽  
pp. 2751-2761 ◽  
Author(s):  
Claire F. Honeycutt ◽  
Jinger S. Gottschall ◽  
T. Richard Nichols

The sensory and neural mechanisms underlying postural control have received much attention in recent decades but remain poorly understood. Our objectives were 1) to establish the decerebrate cat as an appropriate model for further research into the sensory mechanisms of postural control and 2) to observe what elements of the postural response can be generated by the brain stem and spinal cord. Ten animals were decerebrated using a modified premammillary technique, which consists of a premammillary decerebration that is modified with a vertical transection near the subthalamic nucleus to eliminate spontaneous locomotion. Horizontal support surface perturbations were applied to all four limbs and electromyographic recordings were collected from 14 muscles of the right hindlimb. Muscle activation was quantified with tuning curves, which compared increases and decreases in muscle activity to background and graphed the difference against perturbation direction. Parallels were drawn between these tuning curves, which were further quantified with a principal direction and breadth (range of directions of muscle activation), and data collected by other researchers from the intact animal. We found a strong similarity in the direction and breadth of the tuning curves generated in the decerebrate and intact cat. These results support our hypothesis that directionally specific tuning of muscles in response to support surface perturbations does not require the cortex, further indicating a strong role for the brain stem and spinal cord circuits in mediating directionally appropriate muscle activation patterns.


2008 ◽  
Vol 73 (6-7) ◽  
pp. 873-897 ◽  
Author(s):  
Vladimír Špirko ◽  
Ota Bludský ◽  
Wolfgang P. Kraemer

The adiabatic three-dimensional potential energy surface and the corresponding dipole moment surface describing the ground electronic state of HN2+ (Χ1Σ+) are calculated at different levels of ab initio theory. The calculations cover the entire bound part of the potential up to its lowest dissociation channel including the isomerization barrier. Energies of all bound vibrational and low-lying ro-vibrational levels are determined in a fully variational procedure using the Suttcliffe-Tennyson Hamiltonian for triatomic molecules. They are in close agreement with the available experimental numbers. From the dipole moment function effective dipoles and transition moments are obtained for all the calculated vibrational and ro-vibrational states. Statistical tools such as the density of states or the nearest-neighbor level spacing distribution (NNSD) are applied to describe and analyse general patterns and characteristics of the energy and dipole results calculated for the massively large number of states of the strongly bound HN2+ ion and its deuterated isotopomer.


Author(s):  
MAHMUT ÇELIK ◽  
HAKAN GÜRÜN ◽  
ULAŞ ÇAYDAŞ

In this study, the effects of experimental parameters on average surface roughness and material removal rate (MRR) were experimentally investigated by machining of AISI 304 stainless steel plates by magnetic abrasive finishing (MAF) method. In the study in which three different abrasive types were used (Al2O3, B4C, SiC), the abrasive grain size was changed in two different levels (50 and 80[Formula: see text][Formula: see text]m), while the machining time was changed in three different levels (30, 45, 60[Formula: see text]min). Surface roughness values of finished surfaces were measured by using three-dimensional (3D) optical surface profilometer and surface topographies were created. MRRs were measured with the help of precision scales. The abrasive particles’ condition before and after the MAF process was examined and compared using a scanning electron microscope. As a result of the study, the surface roughness values of plates were reduced from 0.106[Formula: see text][Formula: see text]m to 0.028[Formula: see text][Formula: see text]m. It was determined that the best parameters in terms of average surface roughness were 60[Formula: see text]min machining time with 50[Formula: see text][Formula: see text]m B4C abrasives, while the best result in terms of MRR was taken in 30[Formula: see text]min with 50[Formula: see text][Formula: see text]m SiC abrasives.


2018 ◽  
Vol 17 ◽  
pp. 153601211880272 ◽  
Author(s):  
Liliya M. Yamaleyeva ◽  
K. Bridget Brosnihan ◽  
Lane M. Smith ◽  
Yao Sun

Placental oxygenation varies throughout pregnancy. The detection of early changes in placental oxygenation as pregnancy progresses is important for early identification of preeclampsia or other complications. This invited commentary discusses a recent preclinical study on the application of 3-dimensional photoacoustic imaging (PAI) for assessment of regional variations in placental oxygenation and longitudinal analysis of differences in placental oxygenation throughout normal pregnancy and pregnancy associated with hypertension or placental insufficiency in mice. Three-dimensional PAI more accurately reflects oxygen saturation, hemoglobin concentrations, and changes in oxygen saturation in whole placenta compared to 2-dimensional imaging. These studies suggest that PAI is a sensitive tool to detect different levels of oxygen saturation in the placental and fetal vasculature in pathologic and normal pregnancy in mice.


2016 ◽  
Author(s):  
Michal Gallay ◽  
Zdenko Hochmuth ◽  
Ján Kaňuk ◽  
Jaroslav Hofierka

Abstract. The change of hydrological conditions during the evolution of caves in carbonate rocks often results in a complex subterranean geomorphology which comprises specific landforms such as ceiling channels, anastomosing half tubes, or speleothems organised vertically in different levels. Studying such complex environments traditionally requires tedious mapping, however, this is being replaced with terrestrial laser scanning technology. Laser scanning overcomes the problem of reaching high ceilings providing new options to map underground landscapes with unprecedented level of detail and accuracy. The acquired point cloud can be handled conveniently with dedicated software, but applying traditional geomorphometry to analyse the cave surface is limited. This is because geomorphometry has been focused on parameterisation and analysis of surficial terrain. The theoretical and methodological concept has been based on two-dimensional scalar fields which is sufficient for most cases of the surficial terrain. The terrain surface is modelled with a bivariate function of altitude (elevation) and represented by a raster digital elevation model. However, the cave is a three-dimensional entity therefore a different approach is required for geomorphometric analysis. In this paper, we demonstrate the benefits of high resolution cave mapping and 3-D modelling to better understand the palaeohydrography of the Domica cave in Slovakia. This methodological approach adopted traditional geomorphometric methods in a unique manner and also new methods used in 3D computer graphics which can be applied to study other 3-D geomorphological forms


2019 ◽  
Vol 16 (151) ◽  
pp. 20180714 ◽  
Author(s):  
Elsa M. Quicazan-Rubio ◽  
Johan L. van Leeuwen ◽  
Klaas van Manen ◽  
Mike Fleuren ◽  
Bart J. A. Pollux ◽  
...  

Swimming performance of pregnant live-bearing fish is presumably constrained by the additional drag associated with the reproductive burden. Yet, it is still unclear how and to what extent the reproductive investment affects body drag of the females. We examined the effect of different levels of reproductive investment on body drag. The biggest measured increase in body volume due to pregnancy was about 43%, linked to a wetted area increase of about 16% and 69% for the frontal area. We printed three-dimensional models of live-bearing fish in a straight body posture representing different reproductive allocation (RA) levels. We measured the drag and visualized the flow around these models in a flow tunnel at different speeds. Drag grew in a power fashion with speed and exponentially with the increase of RA, thus drag penalty for becoming thicker was relatively low for low speeds compared to high ones. We show that the drag increase with increasing RA was most probably due to bigger regions of flow separation behind the enlarged belly. We suggest that the rising drag penalty with an increasing RA, possibly together with pregnancy-related negative effects on muscle- and abdominal bending performance, will reduce the maximum swimming speed.


Materials ◽  
2019 ◽  
Vol 12 (11) ◽  
pp. 1792 ◽  
Author(s):  
Xiong Wan ◽  
Kai Zhu ◽  
Yanjin Xu ◽  
Baoshuai Han ◽  
Tao Jing

It is well-known that cell morphology plays a vital role in the mechanical properties of the closed-cell aluminum foam. In this work, a three-dimensional (3D) realistic structure was obtained by using the synchrotron X-ray micro-tomography technique and then translated into a numerical model for a further finite-element simulation. In order to investigate the early compressive deformation in the closed-cell aluminum foam, we chose three different strain levels, namely, 0.2% (initiation of plastic strain), 2.8% (propagation of plastic strain band), and 6% (formation of collapse band) to discuss the evolution forms of plastic strain concentration by simulation. We found that the curvature, anisotropy, and distribution of cell volume of adjacent cells played a vital role in the initiation of plastic strain. Furthermore, the phenomenon that plastic strain band propagated along the direction aligned 45° with respect to the orientation of the compression was also investigated in the propagation of the plastic strain band and formation of the collapse band. Finally, the comparison between experimental results and simulation results was performed to illustrate the early location of these three different levels in the whole compressive deformation.


1993 ◽  
Vol 70 (6) ◽  
pp. 2337-2349 ◽  
Author(s):  
D. C. Dunbar ◽  
J. M. Macpherson

1. The electromyographic (EMG) activity of the four neuromuscular compartments in lateral gastrocnemius (LG) of cats was investigated to determine whether these intramuscular subdivisions could be activated differentially during automatic postural corrections. EMG electrodes were surgically implanted into each of the four compartments of left LG-LG1, LG2, LG3, and LGm--in two cats. Electrodes were also implanted into soleus and gluteus medius for comparative purposes. 2. Quiet quadrupedal stance was disturbed first by linearly translating the cats on a movable platform in each of 16 different horizontal directions. Mechanical events during corrections were characterized in terms of the three-dimensional forces exerted by each paw on the platform. EMG and force traces were quantified (area under the curve) and normalized, and tuning curves were constructed that relate muscle response and force change to direction of platform movement. 3. In a second series of trials, translations were presented along one direction only over a series of six velocities ranging from 5 to 16 cm/s. The third series of perturbations, termed the pop-up, consisted of a rapid upward displacement of the support under the left hindlimb only over a series of six amplitudes ranging from 1 to 10 mm. Evoked EMG activity and average change in force were normalized and regressions were computed onto velocity and amplitude, respectively. The slopes of the regressions were compared. 4. EMG tuning curves associated with the multidirectional horizontal translations revealed no differential activity across LG compartments. Similarly, there was no statistical difference among the slopes of the regressions within LG. In contrast, soleus exhibited significantly different slopes from LG for the regressions. Thus it is concluded that LG compartments are not differentially activated during automatic postural responses to perturbations of the support surface.


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